Detection of the Carbapenem Resistance Gene in Gram-negative Rod Bacteria Isolated from Clinical Specimens by Byoung Seon Yang

“…Phenotypic testing using the modified Hodge test confirmed positivity in all 41 strains examined, and carbapenemase inhibitory testing using meropenem+phenyl boronic acid or meropenem+EDTA confirmed positivity in 18 and 8 strains, respectively. …”
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Palladium-Catalyzed Synthesis of Novel Quinazolinylphenyl-1,3,4-thiadiazole Conjugates by Barbara Wołek, Marcin Świątkowski, Agnieszka Kudelko

“…The elaborated protocol makes use of bromo-substituted quinazolines, boronic acid pinacol ester or diboronic acid bis(pinacol)ester of 2,5-diphenyl-1,3,4-thiadiazole, catalytic amounts of [1,10-bis(diphenylphosphino)ferrocene]dichloropalladium(II) Pd(dppf)Cl₂, sodium carbonate, and tetrabutylammonium bromide, which plays the role of a phase-transfer catalyst. …”
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Ferrocene/ β-cyclodextrin based supramolecular nanogels as theranostic systems by Khadijeh Soleimani, Siamak Beyranvand, Zeinab Souri, Zainab Ahmadian, Abdollah Yari, Abbas Faghani, Azim Shams, Mohsen Adeli

“…A supramolecular redox responsive nanogel (NG) with the ability to sense cancer cells and loaded with a releasing therapeutic agent was synthesized using hostguest interactions between polyethylene glycol-grafted-β-cyclodextrin and ferrocene boronic acid. Cyclic voltammetry matched with other spectroscopy and microscopy methods provided strong indications regarding host-guest interactions and formation of the NG. …”
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A massively parallel screening platform for converting aptamers into molecular switches by Alex M. Yoshikawa, Alexandra E. Rangel, Liwei Zheng, Leighton Wan, Linus A. Hein, Amani A. Hariri, Michael Eisenstein, H. Tom Soh

“…Using this approach, we generate multiple switches from a previously published ATP aptamer as well as a newly-selected boronic acid base-modified aptamer for glucose, which respectively undergo signal-on and signal-off switching upon binding their molecular targets with second-scale kinetics. …”
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Exploring Functionalized Magnetic Hydrogel Polyvinyl Alcohol and Chitosan Electrospun Nanofibers by Mónica Guerra, Fábio F. F. Garrudo, Célia Faustino, Maria Emilia Rosa, Maria H. L. Ribeiro

“…The viability of Caco-2 cancer cells was evaluated after being in contact with electrospun PVA + Lys and PVA/CS + Lys nanofibers, with or without boronic acid functionalation, and all were magnetized with IONPs.…”
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2,5-Diaryl 6-hydroxyphenalenones for Single-Molecule Junctions by David Vogel, Luca Ornago, Christina Wegeberg, Alessandro Prescimone, Herreder Zant van, Marcel Mayor

“…The modular synthesis is based on Suzuki cross-coupling of the aryl substituents as boronic acid precursors with 5,8-dibromo-2-(tert-butyl)-4,9-dimethoxy-2,3-dihydro-1H-phenalen-1-one, and the subsequent transformation of the product to the desired 2,5-diaryl 6-hydroxyphenalenone in a reduction/deprotection sequence. …”
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Development of novel arginase inhibitors for therapy of endothelial dysfunction by Jochen eSteppan, Daniel eNyhan, Dan eBerkowitz

“…More importantly, since the 1990s, specific arginase inhibitors such as N-hydroxy-guanidinium or N-hydroxy-nor-L-arginine, and boronic acid derivatives, such as, 2(S)-amino-6-boronohexanoic acid, and S-(2-boronoethyl)-L-cysteine (BEC), that can bridge the binuclear manganese cluster of arginase have been developed. …”
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An LC–MS Assay to Measure Superoxide Radicals and Hydrogen Peroxide in the Blood System by Ioannis Tsamesidis, Chinedu O. Egwu, Pierre Pério, Jean-Michel Augereau, Françoise Benoit-Vical, Karine Reybier

“…We therefore sought to apply a highly sensitive approach, by liquid chromatography coupled to mass spectrometry (UPLC–MS), for the quantification of reactive species such as superoxide radical and hydrogen peroxide using dihydroethidium (DHE) and coumarin boronic acid (CBA) probes respectively through the detection of 2-hydroxyethidium (2OH-E⁺) and 7-hydroxycoumarin (COH). …”
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Efficient Synthesis of Novel 1,3,4-Oxadiazoles Bearing a 4-<i>N,N</i>-Dimethylaminoquinazoline Scaffold via Palladium-Catalyzed Suzuki Cross-Coupling Reactions by Barbara Wołek, Mateusz Werłos, Magdalena Komander, Agnieszka Kudelko

“…The presented synthetic methodology is based on the use of bromine-substituted 2-phenyl-4-<i>N,N</i>-dimethylaminoquinazolines and either a boronic acid pinacol ester or a diboronic acid bis(pinacol) ester of 2,5-diphenyl-1,3,4-oxadiazole. …”
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Synthesis of Polycyclic Ether-Benzopyrans and In Vitro Inhibitory Activity against <i>Leishmania tarentolae</i> by Sarita Singh, Jacob P. Grabowski, Shilpa Pohani, C. Fiore Apuzzo, David C. Platt, Marjorie A. Jones, T. Andrew Mitchell

“…The multi-gram quantity of the requisite aryl bromide was obtained followed by effective Pd-catalyzed coupling with boronic acid derivatives. Compounds were tested in vitro using the parasitic protozoan, <i>Leishmania tarentolae</i>. …”
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Biocatalyzed Flow Oxidation of Tyrosol to Hydroxytyrosol and Efficient Production of Their Acetate Esters by Francesca Annunziata, Martina L. Contente, Cecilia Pinna, Lucia Tamborini, Andrea Pinto

“…The organic layer was purified in-line through a catch-and-release procedure using supported boronic acid that was able to trap HTy and leave the unreacted Ty in solution. …”
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Synthesis and Evaluation of Reactive Oxygen Species Sensitive Prodrugs of a NAMPT Inhibitor FK866 by Zili Xu, Huihui Wang, Haixia Liu, Hongli Chen, Biao Jiang

“…Two prodrugs, with boronic acid as a responsive group to ROS, were prepared and one of the prodrugs <b>122-066</b> also contained a fluorescence carrier. …”
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Phenylboronic Acid-Functionalized Layer-by-Layer Assemblies for Biomedical Applications by Baozhen Wang, Kentaro Yoshida, Katsuhiko Sato, Jun-ichi Anzai

“…Electrochemical glucose sensors have been fabricated by coating the surfaces of electrodes by PBA-modified LbL films, while colorimetric and fluorescence sensors can be prepared by modifying LbL films with boronic acid-modified dyes. In addition, PBA-modified LbL films and microcapsules have successfully been used in the construction of drug delivery systems (DDS). …”
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Halogenated boroxine increases propensity to apoptosis in leukemia (UT‐7) but not non‐tumor cells in vitro by Maida Hadzic, Yitong Sun, Nikolina Tomic, Eirini Tsirvouli, Martin Kuiper, Lejla Pojskic

“…Halogenated boroxine [K2(B3O3F4OH)] (HB) is a derivative of cyclic anhydride of boronic acid, with reproducible anti‐tumor and anti‐proliferative effects in different cell models. …”
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Recent Progress in Diboronic-Acid-Based Glucose Sensors by Ke Nan, Yu-Na Jiang, Meng Li, Bing Wang

“…This paper reviews the glucose recognition mechanism of boronic acids and discusses different glucose sensing strategies based on DBA-derivatives-based sensors reported in the past 10 years. …”
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Ring Opening Copolymerization (ROCOP) of boron-containing anhydride with epoxides as a controlled platform to functional polyesters by Vidal, F, Smith, S, Williams, C

“…The boronic ester-polyesters are deprotected to yield boronic acid- and borate-polyesters; the ionic polymers are water soluble and degradable under alkaline conditions. …”

Exploring new paths towards biological anion recognition by lanthanide complexes by Alexander, C

“…However, the complexes suffer from protodeboronation, leading to the cleavage of boronic acid which is reported for the first time with structural evidence. …”

Carbon Dots Embedded Hybrid Microgel with Phenylboronic Acid as Monomer for Fluorescent Glucose Sensing and Glucose-Triggered Insulin Release at Physiological pH by Jinhua Zhu, Wei Liu, Bowen Zhang, Danyang Zhou, Xiangze Fan, Xiaoge Wang, Xiuhua Liu

“…A multifunctional and biocompatible hybrid microgel (poly(VPBA-AAm)-CD) using N, S-doped carbon dots (CDs) and ethylene glycol dimethacrylate (EGDMA) as cross-linking agents, and 4-vinylbenzene boronic acid (VPBA) and acrylamide (AAm) as monomers, was designed in this work. …”
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Metallic Nanoparticles Adsorbed at the Pore Surface of Polymers with Various Porous Morphologies: Toward Hybrid Materials Meant for Heterogeneous Supported Catalysis by Benjamin Le Droumaguet, Romain Poupart, Mohamed Guerrouache, Benjamin Carbonnier, Daniel Grande

“…These systems have allowed some catalytic molecular reactions to be successfully undertaken, such as the reduction of nitroaromatic compounds or dyes, e.g., methylene blue and Eosin Y, boronic acid-based C–C homocoupling reactions, but also cascade reactions consisting of two catalytic reactions achieved in a row.…”
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Systematic Evaluation of Different Coating Chemistries Used in Thin-Film Microextraction by Jia-Wei Liu, Khaled Murtada, Nathaly Reyes-Garcés, Janusz Pawliszyn

“…The investigated coatings included graphene, graphene oxide, multi-walled carbon nanotubes (MWCNTs), carboxylated MWCNTs, as carbon-based coatings, and polystyrene-divinylbenzene (PS-DVB), octadecyl-silica particles (C18), hydrophilic–hydrophobic balance particles (HLB) and phenyl-boronic acid modified particles (PBA), as SPE-based coatings. …”
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