Mild, Organo-Catalysed Borono-Deamination as a Key to Late-Stage Pharmaceutical Precursors and 18F-Labelled Radiotracers by Raúl M. Pérez-García, Patrick J. Riss, Patrick J. Riss, Patrick J. Riss, Patrick J. Riss

“…A tris(pentafluorophenyl)borane catalysed method for the synthesis of boronic acid esters from aromatic amines in yields of up to 93% was devised. …”
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Electrochromic properties of monosubstituted benzylboronic acid viologen by Tang Shengwei, Niu Junlong, Jia Chunyang

“…Synthesis of monosubstituted benzyl boronic acid viologen (mBBV) has been achieved. The boronic acid group in mBBV can form boronic ester bonds with the hydroxyl groups in polyvinyl alcohol (PVA), resulting in an all-in-one electrochromic gel. …”
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Ketone synthesis via rhodium-catalyzed traceless chelation-controlled hydroacylation reactions by Gao, M

“…</p> <p><strong>Chapter 2</strong> describes a sequential reaction involving alkene hydroacylation, sulfide elimination and boronic acid conjugate addition, which affords products with the initial sulfide coordinating group replaced by a stereochemically defined aryl group.…”

Evaluation of Two Phenotypic Methods for the Detection of Plasmid-Mediated AmpC β-Lactamases among Enterobacteriaceae Isolates by Ronni Mol P, Khalid Mubarak Bindayna, Ganesan Shanthi

“…Conclusion Our findings suggest that inhibitor-based assay using boronic acid can be used for the detection of the isolates that harbor AmpC β-lactamases. …”
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Discovery of a novel activator of KCNQ1-KCNE1 K channel complexes. by Karen Mruk, William R Kobertz

“…Here we show that a simple boronic acid, phenylboronic acid (PBA), activates KCNQ1/KCNE1 complexes co-expressed in Xenopus oocytes at millimolar concentrations. …”
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Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors. by Inglis, SR, Zervosen, A, Woon, E, Gerards, T, Teller, N, Fischer, D, Luxen, A, Schofield, C

“…Here we report aromatic boronic acid inhibitors of the D,D-carboxypeptidase R39 from Actinomadura sp. strain. …”

HPLC with Post-Column Derivatization with Alizarin for Determination of OATD-02, an Anticancer Arginase Inhibitor in Clinical Development by Elzbieta Sobolewska, Magdalena Tyszkiewicz, Roman Blaszczyk, Magdalena Biesaga

“…The aim of this study was to develop an analytical method for selective determination of OATD-02 by high-performance liquid chromatography (HPLC) with post-column derivatization and fluorescence detection (FLD). OATD-02, a new boronic acid derivative, is a highly potent anticancer arginase inhibitor in clinical development. …”
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Arylations mediated by lead(IV) in the presence of formazan and imine ligands by Iqbal, A, Moloney, M, Siddiqui, H, Thompson, A

“…The use of formazan and imine ligands in arylations of β-dicarbonyl systems by phenyl boronic acid/lead(IV) carboxylates is examined. © 2009 Elsevier Ltd. …”

A Quantum Dot-Based FLIM Glucose Nanosensor by Consuelo Ripoll, Angel Orte, Lorena Paniza, Maria Jose Ruedas-Rama

“…When glucose bonded to the boronic acid, the PL was recovered and its lifetime was enhanced. …”
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Benzoxaboroles—Novel Autotaxin Inhibitors by Kristina Kraljić, Dubravko Jelić, Dinko Žiher, Adam Cvrtila, Snježana Dragojević, Verona Sinković, Milan Mesić

“…Other small molecules, with different binding modes, have been investigated as ATX inhibitors for cancer including compounds possessing a boronic acid motif such as HA155. In this work, we targeted new, improved inhibitors of ATX that mimic the important interactions of boronic acid using a benzoxaborole motif as the acidic warhead. …”
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Self-Healing, Stretchable, Biocompatible, and Conductive Alginate Hydrogels through Dynamic Covalent Bonds for Implantable Electronics by Yeonsun Choi, Kyuha Park, Heewon Choi, Donghee Son, Mikyung Shin

“…Herein, plant-inspired conductive alginate hydrogels composed of “boronic acid modified alginate” and “oligomerized epigallocatechin gallate,” which are extracted from plant compounds, are proposed. …”
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Synthesis and evaluation of in vitro bioactivity for polysubstituted N-arylpyrazole derivatives by Naoto Uramaru, En-Chiuan Chang, Wan-Ping Yen, Mou-Yung Yeh, Shin-Hun Juang, Fung Fuh Wong

“…New polysubstituted N-arylpyrazole derivatives were synthesized from N1-arylsydnone with acetylene and boronic acid, including 2-thiophenyl, 3-thiophenyl, 2-benzo[b]thiophenyl, or dibenzothiophenyl-4-boronic acid, via 1,3-dipolar cycloaddition and Suzuki coupling reaction. …”
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Molecular characteristics of extended-spectrum beta-lactamases and qnr determinants in Enterobacter species from Japan. by Hajime Kanamori, Hisakazu Yano, Yoichi Hirakata, Ayako Hirotani, Kazuaki Arai, Shiro Endo, Sadahiro Ichimura, Miho Ogawa, Masahiro Shimojima, Tetsuji Aoyagi, Masumitsu Hatta, Mitsuhiro Yamada, Yoshiaki Gu, Koichi Tokuda, Hiroyuki Kunishima, Miho Kitagawa, Mitsuo Kaku

“…ESBL-producing strains were assessed by the CLSI confirmatory test and the boronic acid disk test. PCR and sequencing were performed to detect CTX-M, TEM, and SHV type ESBLs and PMQR determinants. …”
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Discovery of Immunoproteasome Inhibitors Using Large-Scale Covalent Virtual Screening by Andrea Scarpino, Dávid Bajusz, Matic Proj, Martina Gobec, Izidor Sosič, Stanislav Gobec, György G. Ferenczy, György M. Keserű

“…Large-scale virtual screening of boronic acid derivatives was performed to identify nonpeptidic covalent inhibitors of the &#946;5i subunit of the immunoproteasome. …”
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Validation of a purity method for a Suzuki-Miyaura boronic ester by liquid chromatography with derivatization by John J. Salisbury, William Georgian, Michael Herr, Michele Buetti-Weekly

“…However, analyses of these boronic acid/ester products and their derivatives are rarely discussed. …”
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Structure guided development of potent reversibly binding penicillin binding protein inhibitors. by Woon, E, Zervosen, A, Sauvage, E, Simmons, K, Zivec, M, Inglis, SR, Fishwick, C, Gobec, S, Charlier, P, Luxen, A, Schofield, C

“…Following from the evaluation of different types of electrophiles, combined modeling and crystallographic analyses are used to generate potent boronic acid based inhibitors of a penicillin binding protein. …”

Spatially resolved Suzuki coupling reaction initiated and controlled using a catalytic AFM probe. by Davis, J, Coleman, K, Busuttil, K, Bagshaw, C

“…Herein we report a chemically specific Suzuki coupling reaction between a surface-confined aryl bromide and boronic acid reagents in solution achieved using a catalytic AFM probe.…”

Ameliorative Properties of Boronic Compounds in In Vitro and In Vivo Models of Alzheimer’s Disease by Panchanan Maiti, Jayeeta Manna, Zoe N. Burch, Denise B. Flaherty, Joseph D. Larkin, Gary L. Dunbar

“…Reports that certain boronic compounds can reduce amyloid accumulation and neuroinflammation prompted us to compare trans-2-phenyl-vinyl-boronic-acid-MIDA-ester (TPVA) and trans-beta-styryl-boronic-acid (TBSA) as treatments of deficits in in vitro and in vivo models of AD. …”
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Determination of Extended-Spectrum β-Lactamases and AmpC Production in Uropathogenic Isolates of Escherichia coli and Susceptibility to Fosfomycin by Varsha Gupta, Hena Rani, Nidhi Singla, Neelam Kaistha, Jagdish Chander

“…AmpC screening was done using cefoxitin disc and confirmation was done using cefoxitin/cefoxitin-boronic acid discs. In AmpC positive isolates, ESBLs was detected by modifying CLSI method using boronic acid. …”
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Construction of supramolecular dimer based on benzothiazole derivative through host–guest interaction for photocatalysis by Xin‐Long Li, Yue‐Bo Wang, Ying Wang, Rong‐Zhen Zhang, Rui‐Zhi Dong, Hui Liu, Shengsheng Yu, Ning Han, Ling‐Bao Xing

“…The generated O2⋅− could be used to catalyze the oxidative hydroxylation of aryl boronic acid. Therefore, the 2MPBT‐CB[8] had become a highly efficient photocatalyst for the oxidative hydroxylation of aryl boronic acid. …”
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