Glucose Detection of 4-Mercaptophenylboronic Acid-Immobilized Gold-Silver Core-Shell Assembled Silica Nanostructure by Surface Enhanced Raman Scattering by Xuan-Hung Pham, Bomi Seong, Eunil Hahm, Kim-Hung Huynh, Yoon-Hee Kim, Jaehi Kim, Sang Hun Lee, Bong-Hyun Jun

“…Here we report on a surface-enhanced Raman scattering (SERS) detection of 4-mercaptophenyl boronic acid (4-MPBA)-immobilized gold-silver core-shell assembled silica nanostructure (SiO₂@Au@Ag@4-MPBA) for quantitative, selective detection of glucose in physiologically relevant concentration. …”
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The synthesis of boronic-imine structured compounds and identification of their anticancer, antimicrobial and antioxidant activities by Salih Pasa, Safa Aydın, Sadık Kalaycı, Mehmet Boğa, Metin Atlan, Murat Bingul, Fikrettin Şahin, Hamdi Temel

“…Boronic acid compounds with different substituted groups were handled to synthesize various ligands encoded as B1, B2, B3, B4, B5, B6, B7 and B8. …”
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High-capacity boronate affinity-based template-immobilized surface imprinted silica nanoparticles for rapid, selective, and efficient extraction and determination of lincomycin in... by Yansong Zhang, Yihan Ding, Yidan Ma, Zixin Zhang, Yipei Wang, Daojin Li, Shuangshou Wang

“…Silica nanoparticles and boronic acid ligands 3-fluoro-4-formylphenylboronic acid were used as supporting materials and functional monomers, respectively. …”
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Thiol Peroxidases as Major Regulators of Intracellular Levels of Peroxynitrite in Live <i>Saccharomyces cerevisiae</i> Cells by André Luís Condeles, Fernando Gomes, Marcos Antonio de Oliveira, Luís Eduardo Soares Netto, José Carlos Toledo Junior

“…To these ends, we developed a simple fluorescence assay using coumarin boronic acid (CBA), exploiting that fact that TP and CBA compete for peroxynitrite, with the expectation that higher TP peroxynitrite reductase activity will lower the CBA oxidation. …”
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An integrated flexible and reusable graphene field effect transistor nanosensor for monitoring glucose by Cong Huang, Zhuang Hao, Tianxu Qi, Yunlu Pan, Xuezeng Zhao

“…We present an integrated flexible and reusable graphene-based field effect transistor (GFET) nanosensor for the detection of glucose using pyrene-1-boronic acid (PBA) as the receptor. The nanosensor fabricated on the polyimide performs GFET-based rapid transduction of the glucose-PBA binding, thereby potentially allowing the detection of glucose that are sampled reliably from human bodily fluids (e.g., sweat) in wearable sensing applications. …”
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Data for 'Light-Driven, Posttranslation Installation of Reactive Protein Side Chains' by Josephson, B

“…In situ generation of easily oxidized boronic acid catechol ester derivatives generates RH2C• radicals that form the native (βCH2-γCH2) linkage of natural residues and PTMs (using as little as 100 equiv.) whereas in situ potentiation of pyridylsulfonyl derivatives by Fe(II) generates RF2C• radicals that form equivalent (βCH2-γCF2) linkages to create residues bearing instead ‘zero-size’ H→F labels (using as little as 1-2 eq in 15 min). …”

Developing kinetically facile routes to robust B-F containing compounds for bioconjugation and imaging applications by Booth, AC

“…</p> <p>Chapter 3 reports on investigations into the synthesis and fluoride binding capabilities of 1,8-bis(boryl)-naphthalene scaffolds featuring boronic acid and ester functional groups. These bidentate “ligands” were investigated for potential thermodynamic enhancement that may be attained by chelating fluoride in such a structure, and the opportunity this offered for hydrolytically robust fluoride complexes. …”

Expanding a peptide-covalent probe hybrid for PET imaging of S. aureus driven focal infections by Jyotsna Bhatt Mitra, Saurav Chatterjee, Anuj Kumar, Elina Khatoon, Ashok Chandak, Sutapa Rakshit, Anupam Bandyopadhyay, Archana Mukherjee

“…Radiolabeled UBI (29–41) is a promising SPECT and PET-based tracer for detecting focal infections. 2-APBA (2-acetyl-phenyl-boronic acid), a non-natural amino acid, specifically targets lysyl-phosphatidyl-glycerol (lysyl-PG) on the S. aureus membranes, particularly in AMP-resistant strains. …”
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One-Pot, Optimized Microwave-Assisted Synthesis of Difunctionalized and B–N Co-Doped Carbon Dots: Structural Characterization by Hector Daniel Ibarra-Prieto, Alejandra Garcia-Garcia, Faustino Aguilera-Granja, Diana Carolina Navarro-Ibarra, Ignacio Rivero-Espejel

“…Fourier-transform infrared spectroscopy and Raman spectroscopy analyses confirmed the boronic acid and amine groups’ presence, underscoring the graphitic nature of the core and the co-doping of boron and nitrogen. …”
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HMGB1-RAGE pathway drives peroxynitrite signaling-induced IBD-like inflammation in murine nonalcoholic fatty liver disease by Varun Chandrashekaran, Ratanesh K. Seth, Diptadip Dattaroy, Firas Alhasson, Jacek Ziolenka, James Carson, Franklin G. Berger, Balaraman Kalyanaraman, Anna Mae Diehl, Saurabh Chatterjee

“…Proinflammatory cytokine production was significantly blocked by the specific peroxynitrite scavenger phenyl boronic acid (FBA), AKT inhibition and NADPH oxidase inhibitor Apocynin suggesting NADPH oxidase-dependent peroxynitrite is a key mediator in TLR-4 activation and cytokine release via an AKT dependent pathway. …”
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Detection of Extended-Spectrum β-Lactamases (ESBLs) and AmpC in Class A and Class B Carbapenemase-Producing Enterobacterales by Frank Imkamp, Natalia Kolesnik-Goldmann, Elias Bodendoerfer, Reinhard Zbinden, Stefano Mancini

“…Recently, a modified version of the CLSI ESBL confirmatory combination disc diffusion (CDD) test, which involves the addition of boronic acid and EDTA on discs containing ESBL and AmpC substrates ± inhibitors, has been proposed for the detection of ESBL in class A and class B CPE. …”
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Therapeutic options for extended-spectrum β-lactamases (ESBLs), AmpC β-lactamases producing Escherichia coli and Klebsiella sp. isolated from various clinical samples by Vimal Kumar, Narinder Kaur, Shubham Chauhan, Rosy Bala, Jyoti Chauhan, Harit Kumar, Shivani Devi

“…Guring this period, various clinical samples were collected and further tested for ESBL producing E. coli and Klebsiella sp. by using the Double disc Synergy test, whereas AmpC was detected by the Boronic acid disk potentiation method. Their antibiotic susceptibility patterns were noted. …”
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GLOMERULAR MICROANGIOPATHY WITH MARKED SYSTEMIC THROMBOTIC MICROANGIOPATHY SHORTLY AFTER BORTEZOMIB IN A NEWLY DIAGNOSED POEMS SYNDROME PATIENT by Tarık Onur Tiryaki, Akın Işık, Simge Erdem, Nurana Güller, Gamze Kemeç, Halil Yazıcı, Yasemin Özlük, Işın Kılıçaslan, Sevgi Kalayoğlu Beşışık

“…Abstract: The dipeptide boronic acid analogue bortezomib as a potent and selective inhibitor of the proteasome is used for the treatment of plasma cell dyscrasias such as multiple myeloma (MM). …”
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Preclinical Pharmacokinetics, Tissue Distribution and in vitro Metabolism of FHND6091, a Novel Oral Proteasome Inhibitor by Yang X, Liu A, Yang L, Wen T, Wang J, Shi J, Zhou H, Chen Z, Lei M, Zhu Y

“…Ltd, Nanjing, People’s Republic of ChinaCorrespondence: Meng Lei; Yongqiang Zhu, Tel +86 25 85427621 ; +86 25 85891591, Email hk-lm@163.com; zhyqscu@hotmail.comIntroduction: FHND6091, a novel N-capped dipeptidyl boronic acid proteasome inhibitor with promising pharmacological properties, entirely converted into active form FHND6081 under physiological conditions. …”
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Di(arylcarbazole) Substituted Oxetanes as Efficient Hole Transporting Materials with High Thermal and Morphological Stability for OLEDs by Daiva Tavgeniene, Baohua Zhang, Saulius Grigalevicius

“…A group of di(arylcarbazole)-substituted oxetanes has been prepared in Suzuki reactions by using the key starting material 3,3-di[3-iodocarbazol-9-yl]methyloxetane and various boronic acids (fluorophenylboronic acid, phenylboronic acid or naphthalene-1-boronic acid). …”
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pH/thermal dual-responsive multifunctional drug delivery system for effective photoacoustic imaging-guided tumor chemo/photothermal therapy by Jun Wang, YanYan Wu, Kai Liu, Weitao Yang, Weiwei Zeng, Xiaolong Gao, ShiYuan Liu, Bingbo Zhang

“…The PDA shell not only conjugates with another anticancer bortezomib (Btz) to form pH-sensitive bond through boronic acid and catechol but also acts as a gatekeeper to control the release of doxorubicin and enhance the photothermal effect. …”
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Enabling the use of unstable, hazardous reagents with continuous flow synthesis by Heckman, Laurel Millikan

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Antibiotic resistance profile and co-production of extended spectrum beta lactamases and AmpC in Acinetobacter spp. in a level 1 trauma center from India by Priyam Batra, Surbhi Khurana, Aishwarya Govindaswamy, Anjana Aravinda, Vijeta Bajpai, Muruganantham Ayyanar, Purva Mathur, Rajesh Malhotra

“…Of the strains tested, 15 (9.7%), 17 (11%), 24 (15.6%), 27 (17.5%), 54 (35%), 67 (43.5%), and 72 (46.7%) strains showed ESBL production using CTX/CTX-clavulanate double-disc synergy test (DDST), CTX/CTX-clavulanate E-test, CAZ/CAZ-clavulanate DDST, CAZ/CAZ-clavulanate E-test, Piperacillin/Piperacillin-tazobactam (TZ) DDST, CTR/CTR-Sulbactum DDST, and Piperacillin/Piperacillin-TZ E-test, respectively. 20 (12.9%) and 19 (12.3%) of strains were positive for AmpC production using AmpC disc test and Boronic acid inhibition test, respectively. Genotype analysis using PCR for TEM, SHV, CTXM, PER, and VEB genes was done and 69 (51.5%) strains were positive for TEM gene. …”
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Facile Synthesis and Characterization of Palladium@Carbon Catalyst for the Suzuki-Miyaura and Mizoroki-Heck Coupling Reactions by Hamed M. Alshammari, Obaid F. Aldosari, Mohammad Hayal Alotaibi, Raja L. Alotaibi, Mosaed S. Alhumaimess, Moataz H. Morad, Syed Farooq Adil, Mohammed Rafi Shaik, Mohammad Shahidul Islam, Mujeeb Khan, Abdulrahman Alwarthan

“…The catalysts were tested as a coupling catalyst for Suzuki–Miyaura coupling reactions involving aryl halides and phenyl boronic acid. The optimization of the catalyst by varying the palladium content on the activated carbon yielded Pd/C catalysts with very high catalytic activity for Suzuki reactions of aryl halides and a Mizoroki–Heck cross-coupling reaction of 4-bromoanisol and acrylic acid in an aqueous medium. …”
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Novel Phenothiazine-Bridged Porphyrin-(Hetero)aryl dyads: Synthesis, Optical Properties, In Vitro Cytotoxicity and Staining of Human Ovarian Tumor Cell Lines by Eva Molnar, Emese Gal, Luiza Gaina, Castelia Cristea, Eva Fischer-Fodor, Maria Perde-Schrepler, Patriciu Achimas-Cadariu, Monica Focsan, Luminita Silaghi-Dumitrescu

“…We report here the synthetic procedure applied for the preparation of new AB₃-type and <i>trans</i>-A₂B₂ type <i>meso</i>-halogenophenothiazinyl-phenyl-porphyrin derivatives, their metal core complexation and their peripheral modification using Suzuki–Miyaura cross coupling reactions with various (hetero)aryl (phenothiazinyl, 7-formyl-phenothiazinyl, (9-carbazolyl)-phenyl and 4-formyl-phenyl, phenyl) boronic acid derivatives. The <i>meso</i>-phenothiazinyl-phenyl-porphyrin (MPP) dyes family was thus extended by a series of novel phenothiazine-bridged porphyrin-(hetero)aryl dyads characterized by UV–Vis absorption/emission properties typical to the porphyrin chromophore, slightly modulated by increasing the size of peripheral substituents. …”
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