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541
Use and applications of sulfur dioxide surrogates in the synthesis of sulfonyl derivatives
Published 2018“…The sulfinate intermediates are synthesised from boronic acids and DABSO, under the action of a palladium catalyst. …”
Thesis -
542
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543
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544
Novel halogenation and pallado-biology strategies for biological probes
Published 2016“…This approach was compatible with a wide range of functionally diverse boronic acids, using a water-soluble and phosphine-ligand-free Pd-complex catalyst under fully aqueous conditions. …”
Thesis -
545
Cyclometalated platinum(II) complexes of pyrazole-based, N=C=N-coordinating, terdentate ligands: the contrasting influence of pyrazolyl and pyridyl rings on luminescence.
Published 2008“…Cyclic voltammetry and density functional theory calculations reinforce this interpretation, and suggest that the lowest-energy excited state is probably best described as heavily mixed pi(L)/d(Pt)/p(Cl) --> pi*(L) (IL/MLCT/LLCT) in character. 5-Aryl-substituted analogues of HL(2) are accessible in three steps from 1,3,5-tribromobenzene by Pd-catalyzed cross-coupling with aryl boronic acids, followed by copper-catalyzed bromo-iodo exchange, and subsequent amination with pyrazole under relatively mild conditions also catalyzed by copper. …”
Journal article -
546
Applications of DABSO for the delivery of sulfur dioxide in organic synthesis
Published 2015“…</p> <p><b>Chapter 4</b> documents the development of a palladium-catalysed sulfination reaction of boronic acids to access a range of sulfonyl-containing compounds. …”
Thesis -
547
Studies towards the nucleophilic dearomatisation of electron-deficient heteroaromatics and hydrogen borrowing reactions of methanol
Published 2014“…Finally, a number of nucleophiles, including nitroalkanes, amines, peroxides and boronic acids are applied to one pot methylenation/conjugate addition protocols, affording complex products after two steps in one reaction vessel. …”
Thesis -
548
Palladium(0) Catalyzed Synthesis of (<i>E</i>)-4-Bromo-<i>N</i>-((3-bromothiophen-2-yl)methylene)-2-methylaniline Derivatives via Suzuki Cross-Coupling Reaction: An Exploration of...
Published 2021-09-01“…Suzuki coupling of <b>3b</b> with different boronic acids in the presence of Pd(PPh<sub>3</sub>)<sub>4</sub>/K<sub>3</sub>PO<sub>4</sub> at 90 °C led to the synthesis of the monosubstituted and bisubstituted products <b>5a</b>–<b>5d</b> and <b>6a</b>–<b>6d</b> in moderate yields (33–40% and 31–46%, respectively). …”
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549
Synthesis of Novel Methyl 3-(hetero)arylthieno[3,2-<i>b</i>]pyridine-2-carboxylates and Antitumor Activity Evaluation: Studies In Vitro and In Ovo Grafts of Chick Chorioallantoic M...
Published 2021-03-01“…A series of novel functionalized methyl 3-(hetero)arylthieno[3,2-<i>b</i>]pyridine-2-carboxylates <b>2a</b>–<b>2h</b> were synthesized by C-C Pd-catalyzed Suzuki-Miyaura cross-coupling of methyl 3-bromothieno[3,2-<i>b</i>]pyridine-2-carboxylate with (hetero)aryl pinacol boranes, trifluoro potassium boronate salts or boronic acids. Their antitumoral potential was evaluated in two triple negative breast cancer (TNBC) cell lines—MDA-MB-231 and MDA-MB-468, by sulforhodamine B assay. …”
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550
Fabrication of fluorinated polyamide seawater reverse osmosis membrane with enhanced boron removal
Published 2023“…The fluorine-incorporated strategy employed in this present work offered a new design of the PA layer containing fluorinated molecules to obtain the desired permselectivity of TFC SWRO membranes towards efficient removal of salt and boron acid in seawater desalination.…”
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Journal Article -
551
Microenvironment responsive nanocomposite hydrogel with NIR photothermal therapy, vascularization and anti-inflammation for diabetic infected wound healing
Published 2023-08-01“…In this work, metformin-laden CuPDA NPs composite hydrogel (Met@ CuPDA NPs/HG) was fabricated by dynamic phenylborate bonding of gelatin modified by dopamine (Gel-DA), Cu-loaded polydopamine nanoparticles (CuPDA NPs) with hyaluronic acid modified by phenyl boronate acid (HA-PBA), which possessed good injectability, self-healing, adhesive and DPPH scavenging performance. …”
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552
Synthesis and Antiproliferative Activity of 2,4,6,7-Tetrasubstituted-2<i>H</i>-pyrazolo[4,3-<i>c</i>]pyridines
Published 2021-11-01“…A library of 2,4,6,7-tetrasubstituted-2<i>H</i>-pyrazolo[4,3-<i>c</i>]pyridines was prepared from easily accessible 1-phenyl-3-(2-phenylethynyl)-1<i>H</i>-pyrazole-4-carbaldehyde via an iodine-mediated electrophilic cyclization of intermediate 4-(azidomethyl)-1-phenyl-3-(phenylethynyl)-1<i>H</i>-pyrazoles to 7-iodo-2,6-diphenyl-2<i>H</i>-pyrazolo[4,3-<i>c</i>]pyridines followed by Suzuki cross-couplings with various boronic acids and alkylation reactions. The compounds were evaluated for their antiproliferative activity against K562, MV4-11, and MCF-7 cancer cell lines. …”
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553
Facile Synthesis of Functionalized Phenoxy Quinolines: Antibacterial Activities against ESBL Producing Escherichia coli and MRSA, Docking Studies, and Structural Features Determina...
Published 2022“…Commercially available 6-bromoquinolin-4-ol (3a) was reacted with different types of aryl boronic acids along with Cu(OAc)2 via Chan–Lam coupling methodology utilizing the protic and aprotic and mixed solvents. …”
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554
Facile Synthesis of Functionalized Phenoxy Quinolines: Antibacterial Activities against ESBL Producing <i>Escherichia coli</i> and MRSA, Docking Studies, and Structural Features De...
Published 2022-06-01“…Commercially available 6-bromoquinolin-4-ol (<b>3a</b>) was reacted with different types of aryl boronic acids along with Cu(OAc)<sub>2</sub> via Chan–Lam coupling methodology utilizing the protic and aprotic and mixed solvents. …”
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555
Development and applications of rhodium-catalysed reactions to explore the synthesis of heterocycles
Published 2016“…These methods utilise a variety of novel <em>S</em>- and <em>N</em>-chelating alkenyl aldehyde substrates, and exploit a Rh(I)-catalytic system for the coupling of these aldehydes with alkynes, alkenes and boronic acids.</p> <p>Chapter 1 presents a literature review surveying the development of both intramolecular and intermolecular rhodium-catalysed hydroacylation, paying particular attention to the use of chelating substrates to promote hydroacylation and suppress the decarbonylation process. …”
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556
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557
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558