Stereotactic Radiosurgery in the Management of Brain Metastases: A Case-Based Radiosurgery Society Practice Guideline by Colton Ladbury, MD, Michael Pennock, MD, Tugba Yilmaz, MD, Nii-Kwanchie Ankrah, MBBS, Therese Andraos, MD, Emile Gogineni, DO, Grace Gwe-Ya Kim, PhD, Iris Gibbs, MD, Helen A. Shih, MD, MPH, Jona Hattangadi-Gluth, MD, Samuel T. Chao, MD, Susan C. Pannullo, MD, Ben Slotman, MD, PhD, Kristin J. Redmond, MD, MPH, Simon S. Lo, MB, ChB, Michael Schulder, MD

“…Conclusions: Case-based practice guidelines developed by the Radiosurgery Society provide a practical guide to the common scenarios noted above affecting patients with metastatic brain tumors.…”
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The role of the ZEB1–neuroinflammation axis in CNS disorders by Elham Poonaki, Ulf Dietrich Kahlert, Sven G. Meuth, Ali Gorji

“…The ZEB1–neuroinflammation axis plays a pivotal role in the pathogenesis of different CNS disorders, such as brain tumors, multiple sclerosis, cerebrovascular diseases, and neuropathic pain, by promoting tumor cell proliferation and invasiveness, formation of the hostile inflammatory micromilieu surrounding neuronal tissues, dysfunction of microglia and astrocytes, impairment of angiogenesis, and dysfunction of the blood–brain barrier. …”
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Three-Dimensional Constructive Interference in Steady State (3D CISS) Imaging and Clinical Applications in Brain Pathology by Marco Cavallaro, Alessandra Coglitore, Agostino Tessitore, Karol Galletta, Luciano Frosina, Antonino Cuffari, Roberta Ingrassia, Sarah Caroline Scarcella, Michele Caponnetto, Mirta Longo, Francesca Granata, Sergio Lucio Vinci, Enricomaria Mormina

“…Owing to the very high spatial resolution, the strong hyperintensity of the cerebrospinal fluid signal and the high contrast-to-noise ratio, 3D CISS can be employed in a wide range of scenarios, ranging from the traditional study of cranial nerves, the ventricular system, the subarachnoid cisterns and related pathology to more recently discussed applications, such as the fundamental role it can assume in the setting of acute ischemic stroke, vascular malformations, infections and several brain tumors. In this review, after briefly summarizing its fundamental physical principles, we examine in detail the various applications of 3D CISS in brain imaging, providing numerous representative cases, so as to help radiologists improve its use in imaging protocols in daily clinical practice.…”
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Study of mesenchymal stem cells of adipose tissue effect on the growth of experimental glioma of the rats’ brain by Nikolay Lisianyi, Lyudmila Belska, Vera Semenova, Larisa Stayno

“…Relevant issue is the study of mesenchymal stem cells (MSC) effect on growth of tumors with different structures, including brain tumors.Materials and methods. The study was carried out on white rats. …”
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Cellular Plasticity and Tumor Microenvironment in Gliomas: The Struggle to Hit a Moving Target by Ricardo Gargini, Berta Segura-Collar, Pilar Sánchez-Gómez

“…Brain tumors encompass a diverse group of neoplasias arising from different cell lineages. …”
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Brain Image Segmentation in Recent Years: A Narrative Review by Ali Fawzi, Anusha Achuthan, Bahari Belaton

“…From this review, it is found that deep learning-based and hybrid-based metaheuristic approaches are more efficient for the reliable segmentation of brain tumors. However, these methods fall behind in terms of computation and memory complexity.…”
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In vitro and in vivo modeling systems of supratentorial ependymomas by Emily A. Hatanaka, Emily A. Hatanaka, Joshua J. Breunig, Joshua J. Breunig, Joshua J. Breunig, Joshua J. Breunig, Joshua J. Breunig

“…Ependymomas are rare brain tumors that can occur in both children and adults. …”
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Long-term epilepsy associated-tumors (LEATs): what is new? by Sergio Rosemberg

“…Recent molecular studies have defined new clinicopathological entities, which are recognized by the WHO 2021 classification of brain tumors. Some of them such as diffuse astrocytoma MIB or MYBL1 altered, polymorphous low-grade neuroepithelial tumor of the young (PLNTY), and multilocular and vacuolating neuronal tumor (MVNT) are currently considered LEATs. …”
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Diagnostic Utility of the Immunohistochemical Expression of Serine and Arginine Rich Splicing Factor 1 (SRSF1) in the Differential Diagnosis of Adult Gliomas by Giuseppe Broggi, Lucia Salvatorelli, Davide Barbagallo, Francesco Certo, Roberto Altieri, Elena Tirrò, Michele Massimino, Paolo Vigneri, Elia Guadagno, Grazia Maugeri, Velia D’Agata, Giuseppe Musumeci, Marco Ragusa, Giuseppe Maria Vincenzo Barbagallo, Daniela Russo, Rosario Caltabiano

“…Background: The aim of this study was to investigate the immunohistochemical expression and distribution of serine and arginine rich splicing factor 1 (SRSF1) in a series of 102 cases of both diffuse and circumscribed adult gliomas to establish the potential diagnostic role of this protein in the differential diagnosis of brain tumors. Methods: This retrospective immunohistochemical study included 42 glioblastoma cases, 21 oligodendrogliomas, 15 ependymomas, 15 pilocytic astrocytomas, 5 sub-ependymal giant cell astrocytoma and 4 pleomorphic xanthoastrocytomas. …”
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Patient-derived glioblastoma cell lines with conserved genome profiles of the original tissue by Soon-Chan Kim, Young-Eun Cho, Young-Kyoung Shin, Hyeon Jong Yu, Tamrin Chowdhury, Sojin Kim, Kyung Sik Yi, Chi-Hoon Choi, Sang-Hoon Cha, Chul-Kee Park, Ja-Lok Ku

“…Although accumulating sequence data from brain tumors and matched normal tissues have facilitated a comprehensive understanding of genomic features of GBM, these in silico evaluations could gain more biological credibility when they are verified with in vitro and in vivo models. …”
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Awake craniotomy using a high-flow nasal cannula with oxygen reserve index monitoring - A report of two cases - by Joonhee Gook, Ji-Hye Kwon, Jung Won Choi, Keoungah Kim, Ik Soo Chung, Jeonjin Lee

“…Background Awake craniotomy is a well-tolerated procedure for the resection of brain tumors residing within or close to the eloquent cortical areas. …”
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Polymersomes for Sustained Delivery of a Chalcone Derivative Targeting Glioblastoma Cells by Ana Alves, Ana M. Silva, Joana Moreira, Claúdia Nunes, Salette Reis, Madalena Pinto, Honorina Cidade, Francisca Rodrigues, Domingos Ferreira, Paulo C. Costa, Marta Correia-da-Silva

“…Glioblastoma (GBM) is a primary malignant tumor of the central nervous system responsible for the most deaths among patients with primary brain tumors. Current therapies for GBM are not effective, with the average survival of GBM patients after diagnosis being limited to a few months. …”
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Electroacupuncture prevents cognitive impairments by regulating the early changes after brain irradiation in rats. by Xing-Wen Fan, Fu Chen, Yan Chen, Guan-Hao Chen, Huan-Huan Liu, Shi-Kuo Guan, Yun Deng, Yong Liu, Sheng-Jian Zhang, Wei-Jun Peng, Guo-Liang Jiang, Kai-Liang Wu

“…Our results suggest that EA applied immediately after brain irradiation can prevent cognitive impairments by protecting against the early changes induced by irradiation and may be a novel approach for preventing or ameliorating cognitive impairments in patients with brain tumors who require radiotherapy.…”
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Modernistic and Emerging Developments of Nanotechnology in Glioblastoma-Targeted Theranostic Applications by Buddolla Anantha Lakshmi, Young-Joon Kim

“…Brain tumors such as glioblastoma are typically associated with an unstoppable cell proliferation with aggressive infiltration behavior and a shortened life span. …”
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Capsaicin Nanoparticles as Therapeutic Agents against Gliomas by Evelin Martínez-Benavidez, Inocencio Higuera-Ciapara, Sara Elisa Herrera-Rodríguez, Ofelia Yadira Lugo-Melchor, FranciscoMartín Goycoolea, FranciscoJavier Guerrero Jazo

“…In this review, we analyzed the current literature regarding the development of capsaicin-loaded nanoparticles as a promising approach for the treatment of malignant brain tumors.…”
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In situ mitochondrial biomineralization for drug-free cancer therapy by Ma, Zhaoyu, Zeng, Pei, Zhai, Tianyou, Zhao, Yanli, Liang, Huageng

“…However, this is fatal for some specific clinical tumors, such as brain tumors and neuroma. This study performs a drug-free approach by encapsulating black phosphorus (BP) and calcium peroxide (CaO2) in liposomes with surface-modified triphenylphosphonium (BCLT) to develop mitochondria targeting calcification for cancer therapy without damaging normal cells. …”
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Advanced MR techniques for preoperative glioma characterization: part 1 by Hirschler, L, Sollmann, N, Schmitz-Abecassis, B, Pinto, J, Arzanforoosh, F, Barkhof, F, Booth, T, Calvo-Imirizaldu, M, Cassia, G, Chmelik, M, Clement, P, Ercan, E, Fernández-Seara, MA, Furtner, J, Fuster-Garcia, E, Grech-Sollars, M, Guven, NT, Hatay, GH, Karami, G, Keil, VC, Kim, M, Koekkoek, JAF, Kukran, S, Mancini, L, Nechifor, RE, Özcan, A, Ozturk-Isik, E, Piskin, S, Schmainda, K, Svensson, SF, Tseng, C-H, Unnikrishnan, S, Vos, F, Warnert, E, Zhao, MY, Jancalek, R, Nunes, T, Emblem, KE, Smits, M, Petr, J, Hangel, G

“…Preoperative clinical magnetic resonance imaging (MRI) protocols for gliomas, brain tumors with dismal outcomes due to their infiltrative properties, still rely on conventional structural MRI, which does not deliver information on tumor genotype and is limited in the delineation of diffuse gliomas. …”

Intraoperative squash smear cytology in CNS lesions: A study of 150 pediatric cases by Arpita Jindal, Kanwalpreet Kaur, Kusum Mathur, Vinod Kumari, Himanshi Diwan

“…Background: Tumors of the central nervous system in the pediatric age group occur relatively frequently during the early years of life. Brain tumors are the most common solid malignancies of childhood and only second to acute childhood leukemia. …”
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TMZ-BioShuttle – a reformulated Temozolomide by Waldemar Waldeck, Manfred Wiessler, Volker Ehemann, Ruediger Pipkorn, Herbert Spring, Juergen Debus, Bernd Didinger, Gabriele Mueller, Joerg Langowski, Klaus Braun

“…The re-formulation of TMZ to TMZ-BioShuttle achieved a nearly 10-fold potential of the established pharmaceutic TMZ far beyond the treatment of brain tumors cells and results in an attractive reformulated drug with enhanced therapeutic index.…”
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Qué medimos y cómo medimos. La evaluación de las secuelas neurocognitivas by Isabel Calonge

“…Brain tumors and leukemia survivors frequently suffer severe and persistent deficits in a wide range of neuropsychological functions such as attention, processing speed, memory, visuospatial skills and executive functions. …”
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