Cognitive Functions in Repeated Glioma Surgery by Gabriele Capo, Miran Skrap, Ilaria Guarracino, Miriam Isola, Claudio Battistella, Tamara Ius, Barbara Tomasino

“…Low-grade gliomas (LGG) are slow-growing brain tumors infiltrating the central nervous system which tend to recur, often with malignant degeneration after primary treatment. …”
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RNA Editing in Glioma as a Sexually Dimorphic Prognostic Factor That Affects mRNA Abundance in Fatty Acid Metabolism and Inflammation Pathways by Sheng-Hau Lin, Sean Chun-Chang Chen

“…However, little is known about its prognostic and regulatory roles in glioma, one of the most common types of primary brain tumors. We characterized and analyzed RNA editomes of glioblastoma and isocitrate dehydrogenase mutated (IDH-MUT) gliomas from The Cancer Genome Atlas and the Chinese Glioma Genome Atlas (CGGA). …”
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Carbon Nanotubes: Current Perspectives on Diverse Applications in Targeted Drug Delivery and Therapies by Mohamed Rahamathulla, Rohit R. Bhosale, Riyaz A. M. Osmani, Kasturi C. Mahima, Asha P. Johnson, Umme Hani, Mohammed Ghazwani, Mohammed Y. Begum, Sultan Alshehri, Mohammed M. Ghoneim, Faiyaz Shakeel, Hosahalli V. Gangadharappa

“…The entire collection and compilation of this review concluded the use of CNT approaches and their efficacy and safety for the treatment of various diseases such as brain tumors or cancer via nanotechnology-based drug delivery, phototherapy, gene therapy, antiviral therapy, antifungal therapy, antibacterial therapy and other biomedical applications. …”
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Shedding light on function of long non-coding RNAs (lncRNAs) in glioblastoma by Mehrdad Hashemi, Sophie Mousavian Roshanzamir, Sima Orouei, Pouria Daneii, Rasoul Raesi, Haleh Zokaee, Pooria Bikarannejad, Kiana Salmani, Ramin Khorrami, Mahshid Deldar Abad Paskeh, Shokooh Salimimoghadam, Mohsen Rashidi, Kiavash Hushmandi, Afshin Taheriazam, Maliheh Entezari

“…The brain tumors and especially glioblastoma, are affecting life of many people worldwide and due to their high mortality and morbidity, their treatment is of importance and has gained attention in recent years. …”
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RAR-Dependent and RAR-Independent RXR Signaling in Stem-like Glioma Cells by Amanda Dabrock, Natalie Ernesti, Florian Will, Manaf Rana, Nadja Leinung, Phillip Ehrich, Volker Tronnier, Christina Zechel

“…The significance of RA signaling in malignant brain tumors such as glioblastoma multiforme (GBM) and gliosarcoma (GS) is poorly understood. …”
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Unraveling of Functional Activity of Primary Hippocampal Neuron-Glial Networks in Photodynamic Therapy Based on Tetracyanotetra(aryl)porphyrazines by Maria O. Savyuk, Victoria D. Turubanova, Tatiana A. Mishchenko, Svetlana A. Lermontova, Larisa G. Klapshina, Dmitri V. Krysko, Maria V. Vedunova

“…Considering the significant restructuring of the functional architectonics of neuron-glial networks that can lead to severe impairments in synaptic transmission and loss of brain functions, and the feasibility of direct application of PDT based on <b>pz I</b>–<b>IV</b> in the therapy of brain tumors is highly controversial. Nevertheless, the unique properties of <b>pz I</b>–<b>IV</b> retain a great prospect of their use in the therapy of tumors of another origin and cellular metabolism.…”
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Mapping of Metabolic Heterogeneity of Glioma Using MR-Spectroscopy by Pamela Franco, Irene Huebschle, Carl Philipp Simon-Gabriel, Karam Dacca, Oliver Schnell, Juergen Beck, Hansjoerg Mast, Horst Urbach, Urs Wuertemberger, Marco Prinz, Jonas A. Hosp, Daniel Delev, Irina Mader, Dieter Henrik Heiland

“…Our study indicates a first step into combining the metabolic and molecular traits of lesions for advancing the pre-operative diagnostic workup of brain tumors and improve personalized tumor treatment.…”
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Transcriptome Analysis of Human Glioblastoma Cells Susceptible to Infection with the Leningrad-16 Vaccine Strain of Measles Virus by Yulia Ammour, Olga Susova, George Krasnov, Eugenia Nikolaeva, Vyacheslav Varachev, Yulia Schetinina, Marina Gavrilova, Alexey Mitrofanov, Anna Poletaeva, Ali Bekyashev, Evgeny Faizuloev, Vitaly V. Zverev, Oxana A. Svitich, Tatiana V. Nasedkina

“…Glioblastoma multiforme (GBM) accounts for almost half of all primary malignant brain tumors in adults and has a poor prognosis. Here we demonstrated the oncolytic potential of the L-16 vaccine strain of measles virus (MV) against primary human GBM cells and characterized the genetic patterns that determine the sensitivity of primary human GBM cells to oncolytic therapy. …”
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The Challenges and the Promise of Molecular Targeted Therapy in Malignant Gliomas by Hongxiang Wang, Tao Xu, Ying Jiang, Hanchong Xu, Yong Yan, Da Fu, Juxiang Chen

“…Malignant gliomas are the most common malignant primary brain tumors and one of the most challenging forms of cancers to treat. …”
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Dose-Dependent Suppression of Human Glioblastoma Xenograft Growth by Accelerator-Based Boron Neutron Capture Therapy with Simultaneous Use of Two Boron-Containing Compounds by Vladimir Kanygin, Ivan Razumov, Alexander Zaboronok, Evgenii Zavjalov, Aleksandr Kichigin, Olga Solovieva, Alphiya Tsygankova, Tatiana Guselnikova, Dmitrii Kasatov, Tatiana Sycheva, Bryan J. Mathis, Sergey Taskaev

“…(1) Background: Developments in accelerator-based neutron sources moved boron neutron capture therapy (BNCT) to the next phase, where new neutron radiation parameters had to be studied for the treatment of cancers, including brain tumors. We aimed to further improve accelerator-BNCT efficacy by optimizing dosimetry control, beam parameters, and combinations of boronophenylalanine (BPA) and sodium borocaptate (BSH) administration in U87MG xenograft-bearing immunodeficient mice with two different tumor locations. (2) Methods: The study included two sets of experiments. …”
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P21 Overexpression Promotes Cell Death and Induces Senescence in Human Glioblastoma by Moustafa A. Mansour, Masum Rahman, Ahmad A. Ayad, Arthur E. Warrington, Terry C. Burns

“…High-grade gliomas are the most common and aggressive adult primary brain tumors with a median survival of only 12–15 months. …”
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Antiangiogenic Compound Axitinib Demonstrates Low Toxicity and Antitumoral Effects against Medulloblastoma by Marina Pagnuzzi-Boncompagni, Vincent Picco, Valérie Vial, Victor Planas-Bielsa, Ashaina Vandenberghe, Thomas Daubon, Marie-Alix Derieppe, Christopher Montemagno, Jérôme Durivault, Renaud Grépin, Sonia Martial, Jérôme Doyen, Julie Gavard, Gilles Pagès

“…Moreover, axitinib efficiently reduced the growth rate of experimental brain tumors. Analysis of public databases showed that high expression of axitinib targets correlates with poor prognosis. …”
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Germline Variants in Cancer Predisposition Genes in Pediatric Patients with Central Nervous System Tumors by Aleksa Jovanović, Nataša Tošić, Irena Marjanović, Jovana Komazec, Branka Zukić, Marina Nikitović, Rosanda Ilić, Danica Grujičić, Dragana Janić, Sonja Pavlović

“…Bioinformatic analysis was done using an “in-house” gene list panel, which included 144 genes related to pediatric brain tumors, and the gene list panel Neoplasm (HP:0002664). …”
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An untapped window of opportunity for glioma: targeting therapy-induced senescence prior to recurrence by Cecile Riviere-Cazaux, Lucas P. Carlstrom, Bryan J. Neth, Ian E. Olson, Karishma Rajani, Masum Rahman, Samar Ikram, Moustafa A. Mansour, Bipasha Mukherjee, Arthur E. Warrington, Susan C. Short, Thomas von Zglinicki, Desmond A. Brown, Sandeep Burma, Tamar Tchkonia, Marissa J. Schafer, Darren J. Baker, Sani H. Kizilbash, James L. Kirkland, Terry C. Burns

“…Abstract High-grade gliomas are primary brain tumors that are incredibly refractory long-term to surgery and chemoradiation, with no proven durable salvage therapies for patients that have failed conventional treatments. …”
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Selenoprotein P expression in glioblastoma as a regulator of ferroptosis sensitivity: preservation of GPX4 via the cycling-selenium storage by Xi Zheng, Takashi Toyama, Stephanie Siu, Takayuki Kaneko, Hikari Sugiura, Shota Yamashita, Yoshiteru Shimoda, Masayuki Kanamori, Kotoko Arisawa, Hidenori Endo, Yoshiro Saito

“…Abstract Glioblastoma (GBM) is one of the most aggressive and deadly brain tumors; however, its current therapeutic strategies are limited. …”
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Evolving landscape of research on cancer-related cognitive impairment: A bibliometric analysis by Hongxia Xie, Niu Niu, Zhaoyan Ming, Minghui Wu, Linghui Zeng, Yingchun Zeng

“…Breast cancer and brain tumors were the dominant cancer types. The study population consisted mainly of adult cancer survivors. …”
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Polysialic Acid Sustains the Hypoxia-Induced Migration and Undifferentiated State of Human Glioblastoma Cells by Paolo Rosa, Sofia Scibetta, Giuseppe Pepe, Giorgio Mangino, Luca Capocci, Sam J. Moons, Thomas J. Boltje, Francesco Fazi, Vincenzo Petrozza, Alba Di Pardo, Vittorio Maglione, Antonella Calogero

“…Gliomas are the most common primary malignant brain tumors. Glioblastoma, IDH-wildtype (GBM, CNS WHO grade 4) is the most aggressive form of glioma and is characterized by extensive hypoxic areas that strongly correlate with tumor malignancy. …”
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Bone Morphogenetic Protein 4 Targeting Glioma Stem-Like Cells for Malignant Glioma Treatment: Latest Advances and Implications for Clinical Application by Sonali Nayak, Ashorne Mahenthiran, Yongyong Yang, Mark McClendon, Barbara Mania-Farnell, Charles David James, John A. Kessler, Tadanori Tomita, Shi-Yuan Cheng, Samuel I. Stupp, Guifa Xi

“…Here, we review current research associated with BMP4 in brain tumors, with an emphasis on pediatric malignant gliomas. …”
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Genomic and Transcriptomic Profiling of Brain Metastases by Christopher P. Wardell, Emilie Darrigues, Annick De Loose, Madison P. Lee, Murat Gokden, Issam Makhoul, Alan J. Tackett, Analiz Rodriguez

“…Brain metastases (BM) are the most common brain tumors in adults occurring in up to 40% of all cancer patients. …”
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Identification of Gender- and Subtype-Specific Gene Expression Associated with Patient Survival in Low-Grade and Anaplastic Glioma in Connection with Steroid Signaling by Alex Hirtz, Nolwenn Lebourdais, Magalie Thomassin, Fabien Rech, Hélène Dumond, Hélène Dubois-Pot-Schneider

“…Low-grade gliomas are rare primary brain tumors, which fatally evolve to anaplastic gliomas. …”
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