Development and Validation of a Nomogram Model Based on Hematological Indicators for Predicting the Prognosis of Diffused Gliomas by Song Han, Fang-wen Qu, Fang-wen Qu, Peng-fei Wang, Ying-xin Liu, Shou-wei Li, Chang-xiang Yan

“…BackgroundDiffused gliomas are aggressive malignant brain tumors. Various hematological factors have been proven to predict the prognosis of patients with gliomas. …”
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ARPC5 acts as a potential prognostic biomarker that is associated with cell proliferation, migration and immune infiltrate in gliomas by Yue Ming, Chunyuan Luo, Beihong Ji, Jian Cheng

“…Abstract Background Gliomas are the most common malignant brain tumors, with powerful invasiveness and an undesirable prognosis. …”
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Exploring the Functional Roles of Telomere Maintenance 2 in the Tumorigenesis of Glioblastoma Multiforme and Drug Responsiveness to Temozolomide by Shao-Wei Feng, Zih-Syuan Wu, Yi-Lin Chiu, Shih-Ming Huang

“…It is the most malignant primary central nervous system tumor in adults, accounting for around 15% of intracranial neoplasms and 40–50% of all primary malignant brain tumors. However, the median survival time of GBM patients is still less than 15 months, even after treatment with surgical resection, concurrent chemoradiotherapy, and adjuvant chemotherapy with temozolomide (TMZ). …”
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A general skull stripping of multiparametric brain MRIs using 3D convolutional neural network by Linmin Pei, A. K. Murat, Nourel Hoda M. Tahon, Serafettin Zenkin, Safa Alkarawi, Abdallah Kamal, Mahir Yilmaz, Lingling Chen, Mehmet Er, A. K. Nursima, Rivka Colen

“…For computer-aided methods, the presence of brain skull in structural magnetic resonance imaging (MRI) impacts brain tissue identification, which could result in serious misjudgments, specifically for patients with brain tumors. Though there are several existing works on skull stripping in literature, most of them either focus on healthy brain MRIs or only apply for a single image modality. …”
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3352 Surgical Adjuvant of Immunomodulatory Gene Circuits for Treatment of Glioblastoma by Jordan Matthew Spatz, Ming Ru Wu, Karen Weisinger, Tim Lu, Manish Aghi

“…Importantly, the co-expression of LIGHT and anti-PD-L1 therapies was recently shown to rescue PD-L1 checkpoint blockage in the preclinical models of brain tumors and significant enhance survival outcomes highlighting the benefits of novel combinations of immunomodulatory proteins for treatment of GBM. …”
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Determining the relationship between "microvessel density" and different grades of astrocytoma based on immunohistochemistry for "factor VIII-related antigen" (von Willebrand facto... by Mahzouni Parvin, Mohammadizadeh Fereshteh, Mougouei Kourosh, Moghaddam Noushin, Chehrei Ali, Mesbah Alireza

“…<b>Background:</b> Astrocytic brain tumors are the most common primary central nervous system tumors, which are classified into four grades. …”
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Leveraging a disulfidptosis‑related lncRNAs signature for predicting the prognosis and immunotherapy of glioma by Di Chen, Qiaoqiao Li, Yuan Xu, Yanfei Wei, Jianguo Li, Xuqiang Zhu, Hongjiang Li, Yan Lu, Xianzhi Liu, Dongming Yan

“…Abstract Background Gliomas, a prevalent form of primary brain tumors, are linked with a high mortality rate and unfavorable prognoses. …”
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Detection of Tumor-Specific PTPmu in Gynecological Cancer and Patient Derived Xenografts by Jason Vincent, Sonya E. L. Craig, Mette L. Johansen, Jyosthna Narla, Stefanie Avril, Analisa DiFeo, Susann M. Brady-Kalnay

“…We previously demonstrated its tissue specific distribution in high-grade brain tumors. To extend those studies to other aggressive solid tumor types, we assessed the tissue distribution of PTPmu/SBK4 in a set of matched gynecologic cancer patient derived xenografts (PDXs) and primary patient tumors, as well as a limited cohort of tumors from gynecological cancer patients. …”
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A Cross-Sectional Study to Determine the Prevalence of Calcium Metabolic Disorder in Malignant Childhood Cancers in Patients Admitted to the Pediatric Ward of Vali-Asr Hospital by Heshmat Moayeri, Zohreh Oloomi, Saudatu A. Sambo

“…The most common cancers were ALL, 44 cases (29.7%) followed by brain tumors, 19 cases (12.8%); non-Hodgkin's lymphoma, 16 cases (10.8%); 13 cases of acute myeloid leukemia (AML) (8.8%); 13 cases of Ewing sarcoma (8.8%); osteosarcoma, 9 cases (6.1%); Hodgkin's lymphoma, 6 cases (4.1%); others, 19.1%. …”
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Toward the next generation EGFR inhibitors: an overview of osimertinib resistance mediated by EGFR mutations in non-small cell lung cancer by Yufeng Li, Tianyu Mao, Jing Wang, Hongrui Zheng, Ziyi Hu, Pingping Cao, Suisui Yang, Lingyun Zhu, Shunyao Guo, Xinfei Zhao, Yue Tian, Hua Shen, Fan Lin

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Comparing presentations and outcomes of children with cancer: a study between a lower-middle-income country and a high-income country by Ahmed Farrag, Mohamed Hamdy Ghazaly, Khaled Mohammed, Ruth Volland, Barbara Hero, Frank Berthold

“…Results The most common diagnoses in SECI were leukemia (48.8%), lymphomas (24.1%), brain tumors (1%), and other solid tumors (24.7%), compared to 22.3%, 19.3%, 28.6%, and 26.5% in UKK, respectively. …”
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Cell phones usage and cancers: a review by Ahmad Fuad, Ahmad Farhan, Abdul Rahman, Hejar, Mohammad Aidid, Edre

“…Analyses by anatomic location of the brain tumors within the head revealed no unusual clustering that could be related to increased exposure to RF radiation from cellular telephones. …”
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Treating oligodendroglioma – An analysis of a homogeneous 1p/19q-codeleted and isocitrate dehydrogenase-mutant patient cohort by Luisa Allwohn, Josy Wolfgang, Julia Onken, David Wasilewski, Siyer Roohani, Daniel Zips, Felix Ehret, David Kaul

“…Background: Oligodendrogliomas (ODG) are rare, diffusely infiltrating brain tumors, defined by their 1p/19q-codeletion and isocitrate dehydrogenase (IDH) mutation. …”
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The risk analysis index demonstrates superior discriminative ability in predicting extended length of stay in pituitary adenoma resection patients when compared to the 5-point modi... by Samantha Varela, Rachel Thommen, Kavelin Rumalla, Syed Faraz Kazim, William T. Couldwell, Meic H. Schmidt, Christian A. Bowers

“…Conclusions: Pituitary adenomas account for one of the most common brain tumors in the general population, with resection being the preferred treatment for patients with most hormone producing tumors or those causing compressive symptoms. …”
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Multiparametric Characterization of Intracranial Gliomas Using Dynamic [18F]FET-PET and Magnetic Resonance Spectroscopy by Thomas Pyka, Iwona Krzyzanowska, Axel Rominger, Claire Delbridge, Bernhard Meyer, Tobias Boeckh-Behrens, Claus Zimmer, Jens Gempt

“…In conclusion, FET-PET and MRS provide complementary information to better characterize gliomas before therapy, which is particularly interesting with respect to the increasing use of hybrid PET/MRI for brain tumors.…”
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Algorithmically Deduced <i>FREM2</i> Molecular Pathway Is a Potent Grade and Survival Biomarker of Human Gliomas by Marianna Zolotovskaia, Victor Tkachev, Maxim Sorokin, Andrew Garazha, Ella Kim, Sven Rainer Kantelhardt, Sven-Ernö Bikar, Alja Zottel, Neja Šamec, Denis Kuzmin, Bettina Sprang, Alexey Moisseev, Alf Giese, Victor Efimov, Ivana Jovčevska, Anton Buzdin

“…Gliomas are the most common malignant brain tumors with high mortality rates. Recently we showed that the <i>FREM2</i> gene has a role in glioblastoma progression. …”
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OCT3/4 is a potential immunohistochemical biomarker for diagnosis and prognosis of primary intracranial germ cell tumors: a systematic review and meta-analysis by Yi Zhang, Mucong Li, Jifang Liu, Kan Deng, Huijuan Zhu, Lin Lu, Hui Pan, Renzhi Wang, Yong Yao

“…IntroductionIntracranial germ cell tumors (iGCTs), comprising of germinoma (GE) and non-germinomatous GCT (NGGCT), are a group of heterogenous brain tumors. Immunohistochemical markers, such as placental-like alkaline phosphatase (PLAP), are commonly used in diagnosis but show moderate sensitivity. …”
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Distinct Cerebrovascular Reactivity Patterns for Brain Radiation Necrosis by Giovanni Muscas, Christiaan Hendrik Bas van Niftrik, Martina Sebök, Alessandro Della Puppa, Katharina Seystahl, Nicolaus Andratschke, Michelle Brown, Michael Weller, Luca Regli, Marco Piccirelli, Jorn Fierstra

“…<i>Methods:</i> Eight consecutive patients with primary and secondary brain tumors and a multidisciplinary clinical and radiological diagnosis of radiation necrosis, and fourteen patients with a first diagnosis of glioblastoma underwent BOLD-CVR mapping. …”
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High <i>FREM2</i> Gene and Protein Expression Are Associated with Favorable Prognosis of <i>IDH</i>-WT Glioblastomas by Ivana Jovčevska, Alja Zottel, Neja Šamec, Jernej Mlakar, Maxim Sorokin, Daniil Nikitin, Anton A. Buzdin, Radovan Komel

“…World Health Organization grade IV diffuse gliomas, known as glioblastomas, are the most common malignant brain tumors, and they show poor prognosis. Multimodal treatment of surgery followed by radiation and chemotherapy is not sufficient to increase patient survival, which is 12 to 18 months after diagnosis. …”
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Targeting pediatric cancers via T-cell recognition of the monomorphic MHC class I-related protein MR1 by Aimee du Chatinier, Zsolt Sebestyen, Jürgen Kuball, Stefan Nierkens, Anja Krippner-Heidenreich, Yuyan Lu, Ana P Lopes, Ester Dunnebach, Denise A M H van den Beemt, Sebastiaan van Heesch, Annelisa M. Cornel, Loutje van der Sman, Jip T van Dinter, Marta Arrabito, Marliek van Hoesel, Thomas A Kluiver, Noël M M Dautzenberg, Linde Dekker, Jorik M van Rijn, Juliane L Buhl, Farnaz Barneh, Luca Lo Nigro, Esther Hulleman, Jarno Drost, Olaf T Heidenreich, Weng Chuan Peng

“…The dismal prognosis associated with relapsed/refractory leukemias and high-grade brain tumors highlights the promise to improve survival rates of children with these cancers.…”
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