PEDIATRIC OPTIC PATHWAY GLIOMA: DIENCEPHALIC SYNDROME by A. F. Valiakhmetova, N. A. Mazerkina, L. I. Papusha, O. I. Bydanov, E. M. Tarasova, O. A. Medvedeva, N. K. Serova, L. A. Lazareva, L. V. Shishkina, Yu. Yu. Trunin, G. A. Novichkova, S. K. Gorelyshev, A. I. Karachunsky

“…DC usually occurs in the presence of glioma brain tumors extended into the optic pathway. These tumors are very aggressive and have poor prognosis.Objective: to analyze the clinical course of optic pathway gliomas (OPG s) in patients with and without DC .Material and Methods. …”
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Primary adult choroid plexus carcinomas: a single-center experience with a systematic review by Pengcheng Zuo, Yiying Mai, Zhuang Jiang, Bochao Zhang, Yujin Wang, Mingxin Zhang, Zhen Wu, Junting Zhang, Liwei Zhang, Liwei Zhang

“…ObjectivePrimary adult choroid plexus carcinomas (PACPCs) are extremely rare brain tumors. The existing literature primarily comprises case reports, which limits our understanding of this uncommon disease. …”
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Trace Metal Impurities Effects on the Formation of [⁶⁴Cu]Cu-diacetyl-bis(<i>N</i>⁴-methylthiosemicarbazone) ([⁶⁴Cu]Cu-ATSM) by Mitsuhiro Shinada, Hisashi Suzuki, Masayuki Hanyu, Chika Igarashi, Hiroki Matsumoto, Masashi Takahashi, Fukiko Hihara, Tomoko Tachibana, Chizuru Sogawa, Ming-Rong Zhang, Tatsuya Higashi, Hidemitsu Sato, Hiroaki Kurihara, Yukie Yoshii, Yoshihiro Doi

“…[⁶⁴Cu]Cu-diacetyl-bis(<i>N</i>⁴-methylthiosemicarbazone) ([⁶⁴Cu]Cu-ATSM) is a radioactive hypoxia-targeting therapeutic agent being investigated in clinical trials for malignant brain tumors. For the quality management of [⁶⁴Cu]Cu-ATSM, understanding trace metal impurities’ effects on the chelate formation of ⁶⁴Cu and ATSM is important. …”
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Effect of radiotherapy on cardiac-specific death in patients with non-malignant tumors of central nervous system and related clinical features by Ruxin Wang, Haowen Ye, Yongting Zhao, Li Ma, Jinjing Wei, Ying Wang, Xiaofang Zhang, Lihong Wang

“…ImportanceCardiac-specific death from radiation caused by radiation therapy (RT) in patients with malignant tumors has received extensive attention, however, little is known regarding the potential cardiotoxic effects of RT in patients with non-malignant tumors.Objectives and methodsIn this study, we used the SEER data to explore the incidence of post-radiation cardiovascular complications in patients with non-malignant tumors of central nervous system (CNS), and identify the influencing factors of cardiac-specific death.ResultsUltimately 233, 306 patients were included (97.8% of patients had brain tumors and 2.2% had spinal cord tumors). For patients with non-malignant tumors of CNS, RT {yes (odds ratio [OR] 0.851, 95% confidence interval [CI] 0.774–0.936, p = 0.001, before propensity score matching (PSM); OR 0.792, 95% CI 0.702–0.894, p &lt; 0.001, after PSM) vs. no} was associated with lower risk of cardiac-specific death, other clinical features affecting cardiac death similar to those in patients with non-malignant tumors of CNS receiving RT. …”
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The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma by Zehui Li, Nneka E. Mbah, Jean H. Overmeyer, Jeffrey G. Sarver, Sage George, Christopher J. Trabbic, Paul W. Erhardt, William A. Maltese

“…In addition to providing new insights into the underlying molecular mechanism of methuosis, the results indicate that compounds of the cytotoxic IPP class may have potential for further development as therapeutic agents for brain tumors.…”
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Extracellular vesicles derived from glioblastoma promote proliferation and migration of neural progenitor cells via PI3K-Akt pathway by Jiabin Pan, Shiyang Sheng, Ling Ye, Xiaonan Xu, Yizhao Ma, Xuanran Feng, Lisha Qiu, Zhaohuan Fan, Yi Wang, Xiaohuan Xia, Jialin C. Zheng

“…Abstract Background Glioblastomas are lethal brain tumors under the current combinatorial therapeutic strategy that includes surgery, chemo- and radio-therapies. …”
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Correlation chemical shift imaging with low-power adiabatic pulses and constant-density spiral trajectories by Andronesi, Ovidiu C., Gagoski, Borjan Aleksandar, Adalsteinsson, Elfar, Sorensen, A. Gregory

“…Here we present the first results obtained on phantoms, human volunteers and patients with brain tumors. The patient data obtained by us represent the first clinical demonstration of a feasible and robust multivoxel 2D COSY. …”
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Machine learning in computer-aided diagnosis : medical imaging intelligence and analysis / by Suzuki, Kenji, 1968 Oct. 5-

ZDHHC12 regulates tumor properties through YAP1 in glioblastoma by ZHANG Qixiang, YOU Yongping

“…Background and purpose: Glioblastoma (GBM) is one of the most malignant brain tumors, however, the pathogenesis of GBM has not been thoroughly studied. …”
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IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection by Gunjan Kak, Zachary Van Roy, Cortney E. Heim, Rachel W. Fallet, Wen Shi, Axel Roers, Bin Duan, Tammy Kielian

“…Abstract Background Treatment of brain tumors, epilepsy, or hemodynamic abnormalities requires a craniotomy to access the brain. …”
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DNTTIP2 Expression is Associated with Macrophage Infiltration and Malignant Characteristics in Low-Grade Glioma by Liu YJ, Zeng SH, Qian WH, Tao MX, Zhu YY, Li JP

“…Yuan-Jie Liu,1,2,&ast; Shu-hong Zeng,2,3,&ast; Wei-hua Qian,1 Min-xian Tao,1 Ying-ying Zhu,4 Jie-pin Li1– 3 1Department of Oncology, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang, Jiangsu, 215600, People’s Republic of China; 2Department of Oncology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, Jiangsu, 210029, People’s Republic of China; 3No. 1 Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, People’s Republic of China; 4Department of Oncology, Affiliated Aoyang Hospital of Jiangsu University, Zhangjiagang, Jiangsu, 215600, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jie-pin Li, Email zjgzy027@njucm.edu.cnPurpose: Low-grade gliomas (LGG) are primary brain tumors that often affect predominantly young adults, which usually have a painless course, and have a longer survival period compared to patients with high-grade gliomas. …”
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Efficacy and Safety of Vaccines After Conventional Treatments for Survival of Gliomas: A Systematic Review and Meta-Analysis by Elnaz Amanzadeh Jajin, Saeed Oraee Yazdani, Alireza Zali, Abolghasem Esmaeili

“…Background:Malignant gliomas are known with poor prognosis and low rate of survival among brain tumors. Resection surgery is followed by chemotherapy and radiotherapy in treatment of gliomas which is known as the conventional treatment. …”
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Interleukin-24-mediated antitumor effects against human glioblastoma via upregulation of P38 MAPK and endogenous TRAIL-induced apoptosis and LC3-II activation-dependent autophagy by Seyedeh Maliheh Babazadeh, Mohammad Reza Zolfaghari, Mohsen Zargar, Kazem Baesi, Sayed Younes Hosseini, Amir Ghaemi

“…A novel gene therapy approach to treat deadly brain tumors, recombinant mda-7 adenovirus (Ad/mda-7) efficiently kills glioma cells. …”
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Laryngeal mask airway facilitates a safe and smooth emergence from anesthesia in patients undergoing craniotomy: a prospective randomized controlled study by Cheng-Fong Wei, Yung-Tai Chung

“…Methods This prospective randomized controlled study was conducted on patients undergoing elective craniotomy for brain tumors. After the complement of the surgical procedure, the patients had anesthesia maintained with end-tidal sevoflurane concentration 2.5% and also fully regained muscle power (Time Zero), they were randomly assigned to ETT Group (n = 29) for deep extubation or to LMA Group (n = 29), where the endotracheal tube was replaced by a laryngeal mask airway. …”
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The burden and scope of childhood cancer in displaced patients in Jordan: The King Hussein Cancer Center and Foundation Experience by Rawad Rihani, Sima Jeha, Mayse Nababteh, Carlos Rodriguez-Galindo, Asem Mansour, Iyad Sultan

“…The most common cancer diagnoses were leukemia (41%), lymphoma (25%), solid tumors (24%), retinoblastoma (6%), and brain tumors (4%). Of these, 94% are alive and 51% are still receiving coverage. …”
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Recognition of a Novel Gene Signature for Human Glioblastoma by Chih-Hao Lu, Sung-Tai Wei, Jia-Jun Liu, Yu-Jen Chang, Yu-Feng Lin, Chin-Sheng Yu, Sunny Li-Yun Chang

“…Glioblastoma (GBM) is one of the most common malignant and incurable brain tumors. The identification of a gene signature for GBM may be helpful for its diagnosis, treatment, prediction of prognosis and even the development of treatments. …”
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ABO blood group and risk of glioma: A case control study from Serbia by Azanjac-Arsić Ana, Miletić-Drakulić Svetlana, Vesić Katarina, Tončev Gordana

“…Gliomas are the most common primary brain tumors and the etiology is unknown. The aim of this study was to investigate possible association between incidence in relation to glioma and certain blood groups. …”
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A novel prognostic related lncRNA signature associated with amino acid metabolism in glioma by Qiang Lei, Bo Yuan, Kun Liu, Li Peng, Li Peng, Zhiwei Xia

“…BackgroundGlioma is one of the deadliest malignant brain tumors in adults, which is highly invasive and has a poor prognosis, and long non-coding RNAs (lncRNAs) have key roles in the progression of glioma. …”
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Comprehensive analyses indicated the association between m6A related long non‐coding RNAs and various pathways in glioma by Zhuohui Chen, Wei Zhang, Zhouyi Yan, Mengqi Zhang

“…Abstract Background Glioma is one of the most malignant brain tumors and diseases. N6‐methyladenosine modification (m6A) is the most abundant and prevalent internal chemical modification of mRNA and long non‐coding RNAs (lncRNAs) in eukaryotes. …”
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Andrographolide Induces G2/M Cell Cycle Arrest and Apoptosis in Human Glioblastoma DBTRG-05MG Cell Line via ERK1/2 /c-Myc/p53 Signaling Pathway by Nurul Syamimi Othman, Daruliza Kernain Mohd Azman

“…Human glioblastoma multiforme (GBM) is one of the most malignant brain tumors, with a high mortality rate worldwide. Conventional GBM treatment is now challenged by the presence of the blood–brain barrier (BBB), drug resistance, and post-treatment adverse effects. …”
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