Development and validation of enzyme-linked immunosorbent assays for the measurement of infliximab and anti-drug antibody levels by Dong Xiang, Ninghong Li, Lu Liu, Hengyi Yu, Xiping Li, Tinghui Zhao, Dong Liu, Xuepeng Gong

“…The ADA is captured by on-plate-coated infliximab and recognized by biotin-labeled infliximab. Two bridging ELISA assays were developed and after assay optimization and validation, these assays have been applied in ten patients with inflammatory bowel disease (IBD). …”
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Wine Microbial Consortium: Seasonal Sources and Vectors Linking Vineyard and Winery Environments by Sofia Camilo, Mahesh Chandra, Patrícia Branco, Manuel Malfeito-Ferreira

“…The spoilage yeast <i>Zygosaccharomyces bailii</i> was only recovered from fermented juice. The single species bridging both vineyard and winery environments was the yeast <i>Hanseniaspora uvarum</i>, isolated from insects, rot grapes and grape juice during harvest. …”
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Autophagy activation is required for N6-methyladenosine modification to regulate ferroptosis in hepatocellular carcinoma by Yujia Li, Mei Guo, Yangling Qiu, Mengran Li, Yang Wu, Min Shen, Yingqian Wang, Feng Zhang, Jiangjuan Shao, Xuefen Xu, Zili Zhang, Shizhong Zheng

“…Additionally, while the m6A modification has been shown to regulate various forms of cell death, its role in regulating ferroptosis in HCC has been largely overlooked. Bridging this knowledge gap, our study aimed to elucidate the regulatory influence of m6A modification on HCC ferroptosis. …”
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Competitive Adsorption of NOx and Ozone on the Catalyst Surface of Ozone Converters by Xiaolong Ji, Jean-Marc Clacens, Fabien Can, Antoinette Boréave, Laurent Veyre, Sonia Gil, Valérie Meille

“…It has been proven that on palladium and manganese-based catalysts, the inhibition effect of nitrogen oxides was due to the formation of monodentate nitrites, monodentate, bidentate and bridged nitrates, which are difficult to desorb and decompose into gaseous NOx, either by oxidation or by thermal treatment. …”
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Off the Shelf Thoracic Endovascular Aortic Repair with Sandwich Technique for the Treatment of a Thoraco-Abdominal Penetrating Aortic Ulcer by Tiago F. Ribeiro, Nelson Camacho, Rita S. Ferreira, Frederico Bastos Gonçalves, Maria Emília Ferreira

“…Follow up at 18 months revealed no endoleaks and patent bridging stent grafts without visceral compromise. …”
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Nanobodies in cell-mediated immunotherapy: On the road to fight cancer by Amirhosein Maali, Amirhosein Maali, Monireh Gholizadeh, Monireh Gholizadeh, Saba Feghhi-Najafabadi, Ahmad Noei, Seyedeh Sheila Seyed-Motahari, Seyedeh Sheila Seyed-Motahari, Shafieeh Mansoori, Zahra Sharifzadeh

“…They can promote the cancer therapy either directly by bridging between tumor cells and immune cells and by targeting cancer cells using immune cell-bound nanobodies or indirectly by blocking the inhibitory ligands/receptors. …”
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Cyclin-Dependent Kinase 18 Controls Trafficking of Aquaporin-2 and Its Abundance through Ubiquitin Ligase STUB1, Which Functions as an AKAP by Alessandro Dema, Dörte Faust, Katina Lazarow, Marc Wippich, Martin Neuenschwander, Kerstin Zühlke, Andrea Geelhaar, Tamara Pallien, Eileen Hallscheidt, Jenny Eichhorst, Burkhard Wiesner, Hana Černecká, Oliver Popp, Philipp Mertins, Gunnar Dittmar, Jens Peter von Kries, Enno Klussmann

“…STUB1 functions as an A-kinase anchoring protein (AKAP) tethering PKA to the protein complex and bridging AQP2 and CDK18. The modulation of the protein complex may lead to novel concepts for the treatment of disorders which are caused or are associated with dysregulated AQP2 and for which a satisfactory treatment is not available, e.g., hyponatremia, liver cirrhosis, diabetes insipidus, ADPKD or heart failure.…”
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Survey of extreme heat public health preparedness plans and response activities in the most populous jurisdictions in the United States by Nicole A. Errett, Cat Hartwell, Juliette M. Randazza, Amruta Nori-Sarma, Kate R. Weinberger, Keith R. Spangler, Yuantong Sun, Quinn H. Adams, Gregory A. Wellenius, Jeremy J. Hess

“…Conclusions Jurisdictions can strengthen their extreme heat preparedness by expanding their consideration of at-risk populations to include communities of color, conducting formal evaluations of their responses, and by bridging the gap between the populations determined to be most at-risk and the channels of communication designed to reach them.…”
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Structural insights into the PrpTA toxin–antitoxin system in Pseudoalteromonas rubra by Chenchen Wang, Chuanying Niu, Chuanying Niu, Khan Muhammad Hidayatullah, Lu Xue, Lu Xue, Zhongliang Zhu, Liwen Niu

“…PrpA2–54-form I and II crystal structures both contain a doughnut-shaped hexadecamer formed by eight homodimers organized in a cogwheel-like form via inter-dimer interface dominated by salt bridges and hydrogen bonds. Moreover, PrpA tends to exist in solution as a homodimer other than a homotetramer (SEC-MALS) in the absence of flexible CTD. …”
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Expanding the therapeutic potential of Salvia miltiorrhiza: a review of its pharmacological applications in musculoskeletal diseases by Zhiqiang Ye, Zhiqiang Ye, Zhiqiang Ye, Yuyu Liu, Jintong Song, Jintong Song, Jintong Song, Yin Gao, Yin Gao, Yin Gao, Haiping Fang, Zilong Hu, Min Zhang, Wenwei Liao, Liao Cui, Yanzhi Liu, Yanzhi Liu, Yanzhi Liu

“…This review aims to illuminate the newfound applications of Salvia miltiorrhiza and its active ingredients in the treatment of various MSDs, effectively bridging the gap between an established medicine and an emerging field. …”
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Strengthening social capital in the Sri Lankan population: A qualitative exploration of factors driving the mothers’ support groups initiative during economic crisis by Millawage Supun Dilara Wijesinghe, Upeksha Gayani Karawita, Nissanka Achchi Kankanamalage Ayoma Iroshanee Nissanka, Balangoda Muhamdiramlage Indika Gunawardana, Weerasinghe Mudiyanselage Prasad Chathuranga Weerasinghe, Vithanage Chandima Nayani Vithana, Kanchana Lanka Kumari Mahagamage, Singappuli Arachchilage Sanjeewanie Champika Karunaratne, Ranjith Batuwanthudawe

“…The most common forms of social capital encountered in these themes were bonding, bridging, and linking. Furthermore, strengthening structural social capital is more prominent than strengthening cognitive social capital. …”
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Healthcare professionals’ views on the accessibility and acceptability of perinatal mental health services for South Asian and Black women: a qualitative study by Kiren Bains, Sarah Bicknell, Nikolina Jovanović, Maev Conneely, Rosemarie McCabe, Alex Copello, Jessica Fletcher-Rogers, Stefan Priebe, Jelena Janković

“…Reasons these are currently not being implemented deserve further research, and the potential of novel roles such as peer support workers in bridging the space between ideals and practice needs further investigation.…”
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Anticancer Diiron Vinyliminium Complexes: A Structure–Activity Relationship Study by Simona Braccini, Giorgia Rizzi, Lorenzo Biancalana, Alessandro Pratesi, Stefano Zacchini, Guido Pampaloni, Federica Chiellini, Fabio Marchetti

“…A series of 16 novel diiron complexes of general formula [Fe₂Cp₂(CO)(μ-CO){μ-η¹:η³-C(R′)C(R″)CN(R)(Y)}]CF₃SO₃ (<b>2–7</b>), bearing different substituents on the bridging vinyliminium ligand, was synthesized in 69–95% yields from the reactions of diiron μ-aminocarbyne precursors with various alkynes. …”
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Transcriptional correlates of frequency-dependent brain functional activity associated with symptom severity in degenerative cervical myelopathy by Xing Guo, Jie Li, Qian Su, Jiajun Song, Cai Cheng, Xu Chu, Rui Zhao

“…Conclusion: In conclusion, our study bridges gaps between genes, cell classes, biological processes, and brain functional correlates of DCM. …”
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Nickel(II)-Based Building Blocks with Schiff Base Derivatives: Experimental Insights and DFT Calculations by Néstor Novoa, Carolina Manzur, Thierry Roisnel, Samia Kahlal, Jean-Yves Saillard, David Carrillo, Jean-René Hamon

“…Unexpectedly, the Sonogashira cross-coupling reaction between the 4-iodopyridine derivative <b>6</b> and 4-ethynylpyridine led to the formation of the bis(4-pyridyl) acetylene bridged centrosymmetric dimer [{(L^D)Ni}₂(µ²-py-C≡C-py)] (<b>8</b>). …”
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Sentiment analysis of tweets on alopecia areata, hidradenitis suppurativa, and psoriasis: Revealing the patient experience by Irene Tai-Lin Lee, Sin-Ei Juang, Steven T. Chen, Christine Ko, Christine Ko, Kevin Sheng-Kai Ma, Kevin Sheng-Kai Ma, Kevin Sheng-Kai Ma, Kevin Sheng-Kai Ma

“…There was no definite correlation between the sentiment score and the number of retweets or likes, although negative AA tweets from public accounts received more retweets (p = 0.03511) and likes (p = 0.0228).ConclusionThe use of Twitter sentiment analysis is a promising method to document patients’ experience of skin diseases, which may improve patient care through bridging misconceptions and knowledge gaps between patients and healthcare professionals.…”
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New dual functional CYP450 gene involves in isoflavone biosynthesis in Glycine max L. by Yaying Xia, Chunfeng He, Su Yan, Jinyue Liu, Haijun Huang, Xue Li, Qian Su, Wenbo Jiang, Yongzhen Pang

“…All these results indicated that GmCYP82D26 possesses new and dual enzymatic activity, which bridges the two branches (daidzein and genistein branch) of isoflavonoid pathway in soybean.…”
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Traditional uses, chemical composition and pharmacological activities of Alstonia R. Br. (Apocynaceae): A review by Mi-xue Zhao, Jing Cai, Ying Yang, Jian Xu, Wen-yuan Liu, Toshihiro Akihisa, Wei Li, Takashi Kikuchi, Feng Feng, Jie Zhang

“…This review demonstrates that the genus Alstonia has high clinical application and medicinal value, which will bring the attention of pharmacologists and clinicians to the territory of natural products Additionally, bioactivity-related mechanisms and structure–activity relationships of chemical components are not clear. Only by bridging the gap between bioactivity-related mechanisms and structure–activity relationships of chemical components can the development of Alstonia plants be further promoted.…”
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Specific initial training standards are needed to dive for science in Europe, Occupational vs. Citizen Science Diving by Jean-Pierre Féral, Jean-Pierre Féral, Jean-Pierre Féral, Alain Norro, Alain Norro, Alain Norro

“…This will increase their recognition, acceptance and use for the benefit of scientific work. Building bridges between academic science and non-academic citizen science is possible and this is done by developing coherent projects that produce results that benefit both science and society. …”
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Modeling Tephra Fall and Sediment-Water Flows to Assess Their Impacts on a Vulnerable Building Stock in the City of Arequipa, Peru by J.-C. Thouret, E. Arapa, S. Charbonnier, A. Guerrero, K. Kelfoun, G. Cordoba, D. Rodriguez, O. Santoni

“…In both ravines, overbank flows occurred in key urban areas due to channel sinuosity and constrictions near bridges. Potential impacts on habitat stem from ranges of flow dynamic pressure and measurements of construction material. …”
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