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36901
Transcriptomic Analysis Reveals Candidate Ligand-Receptor Pairs and Signaling Networks Mediating Intercellular Communication between Hair Matrix Cells and Dermal Papilla Cells from...
Published 2023-06-01“…A few pairs, such as LEP-LEPR, IL6-EGFR, RSPO1-LRP6, and ADM-CALCRL, are found to have known or potential roles in hair growth by acting as bridges linking cells. Further, we inferred the signaling axis connecting the cells from transcriptomic data with the advantage of CCCExplorer. …”
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36902
Identification of key genes increasing susceptibility to atrial fibrillation in nonalcoholic fatty liver disease and the potential mechanisms: mitochondrial dysfunction and systemi...
Published 2024-03-01“…Our study also indicates that mitochondrial dysfunction and systemic inflammation may be potential mechanisms bridging NAFLD and AF. Additionally, we identified empagliflozin as a potentially effective therapeutic agent for NAFLD-related AF at the molecular structure level. …”
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36903
CVD phenotyping in oncologic disorders: cardio-miRNAs as a potential target to improve individual outcomes in revers cardio-oncology
Published 2024-01-01“…The circulatory system bridges the interaction between CVD and cancer, which suggests that we need to fully consider the systemic and holistic characteristics of these two diseases in the process of clinical treatment. …”
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36904
Cu<sup>II</sup> Complexes and Coordination Polymers with Pyridine or Pyrazine Amides and Amino Benzamides—Structures and EPR Patterns
Published 2020-12-01“…In most of the cases; this occurred in chelates with the second pyridine, pyrazine or aminophenyl N function. µ-<i>O</i>,<i>N</i> ditopic bridging was frequently observed for the N = pyridine, pyrazine or aminophenyl functions, but not exclusively. …”
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36905
Assessment of Genotoxicity of Zinc Oxide Nanoparticles Using Mosquito as Test Model
Published 2023-10-01“…Both structural aberrations, such as chromosomal breaks, fragments, translocations, and terminal fusions, resulting in the formation of rings and clumped chromosomes, and numerical ones, including hypo- and hyper-aneuploidy at metaphases, bridges, and laggards at the anaphase stage are observed. …”
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36906
<i>Sulfatase</i>-2 Regulates Liver Fibrosis through the TGF-β Signaling Pathway
Published 2021-10-01“…We show here that knockout of SULF2 significantly decreases collagen content, as well as bands of bridging fibrosis, as demonstrated by Sirius red, Masson’s trichrome and α-SMA staining after BDL, CCl<sub>4</sub> and TAA injection in <i>Sulf2</i>-KO versus WT mice. …”
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36907
Relationships between psychopathological symptoms, pandemic-related stress, perceived social support, and COVID-19 infection history: a network analysis in Chinese college students
Published 2024-02-01“…Network differences by COVID-19 infection history (COVID-network vs. no_COVID-network) and network communities were examined.ResultsOur results showed that the most influential nodes were depressed mood, uncontrollable worries, and uncontrollable thoughts about COVID-19. The main bridging symptoms were concentration problems and psychomotor problems. …”
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36908
Microstructure and Pb<sup>2+</sup> Adsorption Properties of Blast Furnace Slag and Fly Ash based Geopolymers
Published 2020-09-01“…Through Fourier transform infrared spectroscopy (FTIR), a band that was assigned to the asymmetric stretching vibration of Si-O-M (M = Na<sup>+</sup> and/or Ca<sup>2+</sup>) non-bridging oxygen type was observed, which suggested that Na and Ca could serve as exchangeable ions in the ionic exchange process. …”
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36909
The Role of Transjugular Intrahepatic Portosystemic Shunt (TIPS) in Treating Portal Hypertension in Patients with Hepatocellular Carcinoma
Published 2023-06-01“…In fact, HCC is often generated from noncirrhotic liver and its treatment benefits from surgical and nonsurgical approaches, potentially bridged by transjugular intrahepatic portosystemic shunt (TIPS) use. …”
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36910
Analysis of PPI networks of transcriptomic expression identifies hub genes associated with Newcastle disease virus persistent infection in bladder cancer
Published 2023-05-01“…Based on paths and modules in the PPI network, the bridges were found mainly in the upregulated mRNA-pathways of p53 signalling, ECM-receptor interaction, and TGF-beta signalling and downregulated mRNA-pathways of antigen processing and presentation, protein processing in endoplasmic reticulum, completement and coagulation cascades in persistent TCCSUPPi cells. …”
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36911
Green, Efficient Detection and Removal of Hg<sup>2+</sup> by Water-Soluble Fluorescent Pillar[5]arene Supramolecular Self-Assembly
Published 2022-07-01“…Herein, we reported the facile construction of a fluorescent supramolecular system (<b>H</b><b>⊃</b><b>G</b>) in 100% water through the self-assembly of carboxylatopillar[5]arene sodium salts (<b>H</b>) and diketopyrrolopyrrole-bridged bis(quaternary ammonium) guest (<b>G</b>) by host–guest interaction. …”
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36912
An Unprecedented CeO<sub>2</sub>/C Non-Noble Metal Electrocatalyst for Direct Ascorbic Acid Fuel Cells
Published 2023-09-01“…Furthermore, our density functional theory (DFT) calculation reveals that that the proton of the hydroxyl group of AA can easily migrate to the bridging O sites of CeO<sub>2</sub>, resulting in a faster AAOR with respect to the pristine carbon, -COOH, and -C=O sites of carbon. …”
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36913
Quantum-Chemistry Study of the Hydrolysis Reaction Profile in Borate Networks: A Benchmark
Published 2024-03-01“…The modeled system consisted of two boron atoms, bridging oxygen atoms, and varying numbers of water molecules. …”
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36914
Success in vaccination programming through community health workers: a qualitative analysis of interviews and focus group discussions from Nepal, Senegal and Zambia
Published 2024-04-01“…With the continued projection of health worker shortages, especially in low-income countries, community health workers bridged the equity gap in access to vaccination services by enabling wider reach to underserved populations. …”
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36915
Time-course gait pattern analysis in a rat model of foot drop induced by ventral root avulsion injury
Published 2022-12-01“…We conclude that the proposed foot drop rat model with a video-based gait analysis approach can precisely detect the foot drop pattern induced by VRA in rats, which can provide insight into the compensatory changes and recovery in gait patterns and might be useful for serving as a translational platform bridging human and animal studies for developing novel therapeutic strategies for foot drop.…”
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36916
“The Gems of Water”: a co-created scientist-citizen approach for water quality monitoring
Published 2024-03-01“…“The Gems of Water” project contributes to data collection of rarely monitored compounds in rural and remote areas through a scientist-citizen approach, addressing knowledge gaps on water quality and building bridges between science and society. The outlook is for such an innovative approach to support bottom-up management actions which can lead to alternative solutions in water quality management.…”
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36917
Technical Outcome, Clinical Success, and Complications of Low-Milliampere Computed Tomography Fluoroscopy-Guided Drainage of Lymphoceles Following Radical Prostatectomy with Pelvic...
Published 2022-10-01“…Low-milliampere CTF-guided drainage is a safe treatment option in patients with lymphoceles following RP with pelvic LND characterized by high technical and good clinical success rates, which provides rapid symptom relief and serves as definite treatment or as a bridging therapy prior to laparoscopic marsupialisation.…”
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36918
Blapstin, a Diapause-Specific Peptide-Like Peptide from the Chinese Medicinal Beetle Blaps rhynchopetera, Has Antifungal Function
Published 2023-06-01“…It is a 41-amino-acid diapause-specific peptide (DSP)-like peptide stabilized by three disulfide bridges and shows antifungal activity against Candida albicans and Trichophyton rubrum with MICs of 7 μM and 5.3 μM, respectively. …”
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36919
Pharmacokinetics and bioavailability of a new long-acting insulin analog in healthy Chinese volunteers: an open, randomized, single-dose, two-period and two-sequence cross-over stu...
Published 2023-12-01“…The geometric mean ratios of Cmax, AUC0–t and AUC0–∞ of T over R were 98.7% (90% CI: 92.7%–105.2%), 102.6% (90% CI: 100.0%–105.3%) and 102.8% (90% CI: 100.1%–105.5%).Conclusion: The overall PK profile of the two formulations of INS068 injection was comparable in healthy subjects, and the pen injector of INS068 had adequate safety and tolerability, supporting it as a new formulation in a phase III study and bridging PK data from early phase clinical trials.Clinical Trial Registration:clinicaltrials.gov, identifier: NCT05336071…”
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36920
Cytopenias following anti-CD19 chimeric antigen receptor (CAR) T cell therapy: a systematic analysis for contributing factors
Published 2022-12-01“…Subgroup analysis showed increased incidence of cytopenias in subgroups with lower median age, proportion of males (<65%) and proportion of bridging therapy (<80%) and in the subgroup with a median line of prior therapy ≥3. …”
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