Transcriptomic Analysis Reveals Candidate Ligand-Receptor Pairs and Signaling Networks Mediating Intercellular Communication between Hair Matrix Cells and Dermal Papilla Cells from... by Sen Ma, Dejun Ji, Xiaolong Wang, Yuxin Yang, Yinghua Shi, Yulin Chen

“…A few pairs, such as LEP-LEPR, IL6-EGFR, RSPO1-LRP6, and ADM-CALCRL, are found to have known or potential roles in hair growth by acting as bridges linking cells. Further, we inferred the signaling axis connecting the cells from transcriptomic data with the advantage of CCCExplorer. …”
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Identification of key genes increasing susceptibility to atrial fibrillation in nonalcoholic fatty liver disease and the potential mechanisms: mitochondrial dysfunction and systemi... by Baiyin Zhong, Zhonghui Xie, Jianhong Zhang, Xing Xie, Yuankang Xie, Binhui Xie, Jing Wang, Chuanbin Liu

“…Our study also indicates that mitochondrial dysfunction and systemic inflammation may be potential mechanisms bridging NAFLD and AF. Additionally, we identified empagliflozin as a potentially effective therapeutic agent for NAFLD-related AF at the molecular structure level. …”
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CVD phenotyping in oncologic disorders: cardio-miRNAs as a potential target to improve individual outcomes in revers cardio-oncology by Ming Yang, Tiepeng Li, Shujin Guo, Kangping Song, Chuhui Gong, Ning Huang, Dejiang Pang, Hengyi Xiao

“…The circulatory system bridges the interaction between CVD and cancer, which suggests that we need to fully consider the systemic and holistic characteristics of these two diseases in the process of clinical treatment. …”
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Cu^II Complexes and Coordination Polymers with Pyridine or Pyrazine Amides and Amino Benzamides—Structures and EPR Patterns by Ines Wackerbarth, Ni Nyoman Agnes Tri Widhyadnyani, Simon Schmitz, Kathrin Stirnat, Katharina Butsch, Ingo Pantenburg, Gerd Meyer, Axel Klein

“…In most of the cases; this occurred in chelates with the second pyridine, pyrazine or aminophenyl N function. µ-<i>O</i>,<i>N</i> ditopic bridging was frequently observed for the N = pyridine, pyrazine or aminophenyl functions, but not exclusively. …”
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Assessment of Genotoxicity of Zinc Oxide Nanoparticles Using Mosquito as Test Model by Kanwaljit Kaur Ahluwalia, Kritika Thakur, Amrik Singh Ahluwalia, Abeer Hashem, Graciela Dolores Avila-Quezada, Elsayed Fathi Abd_Allah, Neelam Thakur

“…Both structural aberrations, such as chromosomal breaks, fragments, translocations, and terminal fusions, resulting in the formation of rings and clumped chromosomes, and numerical ones, including hypo- and hyper-aneuploidy at metaphases, bridges, and laggards at the anaphase stage are observed. …”
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<i>Sulfatase</i>-2 Regulates Liver Fibrosis through the TGF-β Signaling Pathway by Ikuo Nakamura, Faizal Z. Asumda, Catherine D. Moser, Yoo Na N. Kang, Jin-Ping Lai, Lewis R. Roberts

“…We show here that knockout of SULF2 significantly decreases collagen content, as well as bands of bridging fibrosis, as demonstrated by Sirius red, Masson’s trichrome and α-SMA staining after BDL, CCl₄ and TAA injection in <i>Sulf2</i>-KO versus WT mice. …”
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Relationships between psychopathological symptoms, pandemic-related stress, perceived social support, and COVID-19 infection history: a network analysis in Chinese college students by Chi Kei Krystal Lee, Kwun Nam Joe Chan, Sau Man Corine Wong, Hou Sem Gabbie Wong, Hiu Ching Janet Lei, Yuen Kiu So, Shi Cheng Vivian Fung, Sai Ting Ryan Chu, Kar Kin Albert Chung, Pak Wing Calvin Cheng, Ka Ying Heidi Lo, Wai Chi Chan, Wing Chung Chang, Wing Chung Chang

“…Network differences by COVID-19 infection history (COVID-network vs. no_COVID-network) and network communities were examined.ResultsOur results showed that the most influential nodes were depressed mood, uncontrollable worries, and uncontrollable thoughts about COVID-19. The main bridging symptoms were concentration problems and psychomotor problems. …”
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Microstructure and Pb²⁺ Adsorption Properties of Blast Furnace Slag and Fly Ash based Geopolymers by T. J. Medina, S. P. Arredondo, R. Corral, A. Jacobo, R. A. Zárraga, C. A. Rosas, F. G. Cabrera, J. M. Bernal

“…Through Fourier transform infrared spectroscopy (FTIR), a band that was assigned to the asymmetric stretching vibration of Si-O-M (M = Na⁺ and/or Ca²⁺) non-bridging oxygen type was observed, which suggested that Na and Ca could serve as exchangeable ions in the ionic exchange process. …”
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The Role of Transjugular Intrahepatic Portosystemic Shunt (TIPS) in Treating Portal Hypertension in Patients with Hepatocellular Carcinoma by Daniele Balducci, Michele Montori, Federico De Blasio, Alessandro Di Bucchianico, Maria Eva Argenziano, Gianluca Svegliati Baroni, Emidio Scarpellini

“…In fact, HCC is often generated from noncirrhotic liver and its treatment benefits from surgical and nonsurgical approaches, potentially bridged by transjugular intrahepatic portosystemic shunt (TIPS) use. …”
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Analysis of PPI networks of transcriptomic expression identifies hub genes associated with Newcastle disease virus persistent infection in bladder cancer by Umar Ahmad, Syahril Abdullah, De Ming Chau, Suet Lin Chia, Khatijah Yusoff, Soon Choy Chan, Teng Aik Ong, Azad Hassan Razack, Abhi Veerakumarasivam

“…Based on paths and modules in the PPI network, the bridges were found mainly in the upregulated mRNA-pathways of p53 signalling, ECM-receptor interaction, and TGF-beta signalling and downregulated mRNA-pathways of antigen processing and presentation, protein processing in endoplasmic reticulum, completement and coagulation cascades in persistent TCCSUPPi cells. …”
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Green, Efficient Detection and Removal of Hg²⁺ by Water-Soluble Fluorescent Pillar[5]arene Supramolecular Self-Assembly by Xiaomei Jiang, Lingyun Wang, Xueguang Ran, Hao Tang, Derong Cao

“…Herein, we reported the facile construction of a fluorescent supramolecular system (<b>H</b><b>⊃</b><b>G</b>) in 100% water through the self-assembly of carboxylatopillar[5]arene sodium salts (<b>H</b>) and diketopyrrolopyrrole-bridged bis(quaternary ammonium) guest (<b>G</b>) by host–guest interaction. …”
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An Unprecedented CeO₂/C Non-Noble Metal Electrocatalyst for Direct Ascorbic Acid Fuel Cells by Chenxi Qiu, Qiang Zhou, Rui Gao, Yizheng Guo, Jiaqi Qin, Dongqi Wang, Yujiang Song

“…Furthermore, our density functional theory (DFT) calculation reveals that that the proton of the hydroxyl group of AA can easily migrate to the bridging O sites of CeO₂, resulting in a faster AAOR with respect to the pristine carbon, -COOH, and -C=O sites of carbon. …”
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Quantum-Chemistry Study of the Hydrolysis Reaction Profile in Borate Networks: A Benchmark by Francesco Muniz-Miranda, Leonardo Occhi, Francesco Fontanive, Maria Cristina Menziani, Alfonso Pedone

“…The modeled system consisted of two boron atoms, bridging oxygen atoms, and varying numbers of water molecules. …”
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Success in vaccination programming through community health workers: a qualitative analysis of interviews and focus group discussions from Nepal, Senegal and Zambia by William Kilembe, Matthew C Freeman, Robert Bednarczyk, Zoe Sakas, Anna S Ellis, Moussa Sarr, Kyra A Hester, Sameer Dixit, Emily A Ogutu, Katie Rodriguez, Chandni Jaishwal, Chenmua Yang, Anindya Sekhar Bose

“…With the continued projection of health worker shortages, especially in low-income countries, community health workers bridged the equity gap in access to vaccination services by enabling wider reach to underserved populations. …”
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Time-course gait pattern analysis in a rat model of foot drop induced by ventral root avulsion injury by Shu-Yen Chan, Shu-Yen Chan, Chi-Wei Kuo, Tsai-Tsen Liao, Tsai-Tsen Liao, Chih-Wei Peng, Chih-Wei Peng, Tsung-Hsun Hsieh, Tsung-Hsun Hsieh, Tsung-Hsun Hsieh, Ming-Yuan Chang, Ming-Yuan Chang, Ming-Yuan Chang

“…We conclude that the proposed foot drop rat model with a video-based gait analysis approach can precisely detect the foot drop pattern induced by VRA in rats, which can provide insight into the compensatory changes and recovery in gait patterns and might be useful for serving as a translational platform bridging human and animal studies for developing novel therapeutic strategies for foot drop.…”
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“The Gems of Water”: a co-created scientist-citizen approach for water quality monitoring by Caterina Cacciatori, Caterina Cacciatori, Giulio Mariani, Sara Comero, Daniela Marin, Maria Cabrera, Jennifer Bon-Tavarnese, Joel Gaggstatter, Simona Tavazzi, Roberta Maffettone, Jackie Myers, Vincent Pettigrove, Bernd Manfred Gawlik

“…“The Gems of Water” project contributes to data collection of rarely monitored compounds in rural and remote areas through a scientist-citizen approach, addressing knowledge gaps on water quality and building bridges between science and society. The outlook is for such an innovative approach to support bottom-up management actions which can lead to alternative solutions in water quality management.…”
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Technical Outcome, Clinical Success, and Complications of Low-Milliampere Computed Tomography Fluoroscopy-Guided Drainage of Lymphoceles Following Radical Prostatectomy with Pelvic... by Melvin D’Anastasi, Simone Ebenberger, Abdulmajeed Alghamdi, Andreas Helck, Annika Herlemann, Christian Stief, Wael Khoder, Christoph G. Trumm, Robert Stahl

“…Low-milliampere CTF-guided drainage is a safe treatment option in patients with lymphoceles following RP with pelvic LND characterized by high technical and good clinical success rates, which provides rapid symptom relief and serves as definite treatment or as a bridging therapy prior to laparoscopic marsupialisation.…”
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Blapstin, a Diapause-Specific Peptide-Like Peptide from the Chinese Medicinal Beetle Blaps rhynchopetera, Has Antifungal Function by La-Mei Zhang, Min Yang, Sheng-Wen Zhou, Hao Zhang, Ying Feng, Lei Shi, Dong-Sheng Li, Qiu-Min Lu, Zhong-He Zhang, Min Zhao

“…It is a 41-amino-acid diapause-specific peptide (DSP)-like peptide stabilized by three disulfide bridges and shows antifungal activity against Candida albicans and Trichophyton rubrum with MICs of 7 μM and 5.3 μM, respectively. …”
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Pharmacokinetics and bioavailability of a new long-acting insulin analog in healthy Chinese volunteers: an open, randomized, single-dose, two-period and two-sequence cross-over stu... by Ke-Guang Chen, Ye-Hui Zhang, Pan-Pan Ye, Xue-Hu Gao, Lin-Lin Song, Hai-Yan Zhou, Qian Li, Fu-Rong Zhao, Jin-Yi Shi, Xin-Mei Yang, Kai Shen, Sheng Feng, Wei Zhao, Wei Zhao

“…The geometric mean ratios of Cmax, AUC0–t and AUC0–∞ of T over R were 98.7% (90% CI: 92.7%–105.2%), 102.6% (90% CI: 100.0%–105.3%) and 102.8% (90% CI: 100.1%–105.5%).Conclusion: The overall PK profile of the two formulations of INS068 injection was comparable in healthy subjects, and the pen injector of INS068 had adequate safety and tolerability, supporting it as a new formulation in a phase III study and bridging PK data from early phase clinical trials.Clinical Trial Registration:clinicaltrials.gov, identifier: NCT05336071…”
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Cytopenias following anti-CD19 chimeric antigen receptor (CAR) T cell therapy: a systematic analysis for contributing factors by Yuan Xia, Jue Zhang, Jing Li, Lina Zhang, Jianyong Li, Lei Fan, Lijuan Chen

“…Subgroup analysis showed increased incidence of cytopenias in subgroups with lower median age, proportion of males (<65%) and proportion of bridging therapy (<80%) and in the subgroup with a median line of prior therapy ≥3. …”
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