Diabetes Induces a Transcriptional Signature in Bone Marrow–Derived CD34⁺ Hematopoietic Stem Cells Predictive of Their Progeny Dysfunction by Yuri D’Alessandra, Mattia Chiesa, Vera Vigorelli, Veronica Ricci, Erica Rurali, Angela Raucci, Gualtiero Ivanoe Colombo, Giulio Pompilio, Maria Cristina Vinci

“…Total RNA of BM-derived CD34⁺ stem cells purified from sternal biopsies of patients undergoing coronary bypass surgery with or without DM (CAD and CAD-DM patients) was sequenced. …”
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A Clinical Case of Surgical Treatment of a Patient with Two Postinfarction Left Ventricular Aneurysms by Olena K. Gogayeva, Serhii A. Rudenko, Oleksandr O. Nudchenko, Svitlana V. Fedkiv

“…After discussing the patient’s data, the cardiac team performed emergency on-pump coronary bypass surgery, resection of the LV aneurysm with thrombectomy. …”
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MANAGEMENT OF CEREBRAL OXYGENATION IN ORDER TO REDUCE THE DEVELOPMENT OF POST-OPERATIVE COMPLICATIONS IN HIGH-RISK PATIENTS UNDERGOING CARDIAC SURGERY by P. P. PEROVSKIY, D. N. PONOMАREV, E. V. FOMINSKIY, S. M. ISMOILOV, N. А. TАRKUNOV, V. А. SHMYREV, G. B. MOROZ, V. N. LOMIVOROTOV, V. V. LIKHVАNTSEV, V. V. LOMIVOROTOV

“…Subjects: Patients who underwent coronary bypass surgery and/or cardiac valve surgery with cardiopulmonary bypass, were randomly divided into two groups: the interventional group (n = 60), where a special protocol was used to manage desaturation episodes, and the control group (n = 60) where only blinded monitoring of cerebral oximetry was used. …”
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Comparison of Risk Factors, Prevalence, Type of Treatment, and Mortality Rate for Myocardial Infarction in Diabetic and Non-diabetic Older Adults: A Cohort Study by Parisa Janjani, Yaser Salehabadi, Sayeh Motevaseli, Reza Heidari Moghadam, Soraya Siabani, Nahid Salehi

“…There were no significant differences between the two groups regarding the variables of place of residence, literacy level, smoking, history of stroke, coronary angioplasty and coronary artery bypass surgery. In addition, there was no significant difference in mortality rate and type of reperfusion treatment between the two groups. …”
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Factors determining the readiness of a patient with coronary artery disease to use telemedicine technologies for rehabilitation: prospective cohort study by Tatiana N. Zvereva, Anastasia A. Pronina, Anastasia V. Babichuk, Svetlana A. Pomeshkina, Olga L. Barbarash

“…MATERIALS AND METHODS: A study of 213 patients treated for artery disease and preparing for planned coronary bypass surgery was conducted. Gender, age, socioeconomic factors, and digital literacy were analyzed. …”
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Characterization of “ICU‐30”: A Binary Composite Outcome for Neonates With Critical Congenital Heart Disease by Monique M. Gardner, Garrett Keim, Jill Hsia, Anh D. Mai, J. William Gaynor, Andrew C. Glatz, Nadir Yehya

“…Background Neonates with heart disease requiring cardiopulmonary bypass surgery are at high risk for mortality and morbidity. …”
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Acute Kidney Injury in Cardiac Surgery with Cardiopulmonary Bypass by Yu. S. Polushin, D. V. Sokolov, N. S. Molchan, R. V. Аkmalova, O. V. Galkina

“…Inclusion criteria: age over 18 years, duration of surgery (coronary bypass surgery, prosthetic heart valves) from 90 to 180 minutes, no signs of end stage kidney disease. …”
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Case Report: Variegate porphyria disclosed by post-gastric bypass complications and causing predominant painful sensorimotor axonal peripheral neuropathy by Edwige Collaud, Luis Wittwer, Luis Wittwer, Anna-Elisabeth Minder, Jean-Marie Annoni, Elisabeth I. Minder, Joelle N. Chabwine, Joelle N. Chabwine

“…Treated with carbohydrate load, neurorehabilitation, and analgesics, she slowly recovered to full mobility, with partial autonomy in her daily life activities, although fatigue and severe pain persisted, preventing her from returning to work.Conclusion: This case documents gastric bypass surgery as a trigger of severe VP invalidating neurological symptoms and illustrates how the delayed diagnosis and post-interventional complications could have been prevented by screening for porphyria cardinal symptoms prior to the intervention. …”
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Increased miR-142 Levels in Plasma and Atherosclerotic Plaques from Peripheral Artery Disease Patients with Post-Surgery Cardiovascular Events by Teodora Barbalata, Oriana E. Moraru, Camelia S. Stancu, Yvan Devaux, Maya Simionescu, Anca V. Sima, Loredan S. Niculescu

“…We aimed to determine the potential of microRNAs to predict the appearance of cardiovascular events (CVEs) in patients with peripheral artery disease (PAD) following femoral artery bypass surgery. Forty-seven PAD patients were enrolled and divided into two groups, without CVEs (<i>n</i> = 35) and with CVEs (<i>n</i> = 12), during 1 year follow-up. …”
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Effect of fluid loading with normal saline and 6% hydroxyethyl starch on stroke volume variability and left ventricular volume by Kanda H, Hirasaki Y, Iida T, Kanao M, Toyama Y, Kunisawa T, Iwasaki H

“…Hirotsugu Kanda,1 Yuji Hirasaki,2 Takafumi Iida,1 Megumi Kanao,1 Yuki Toyama,1 Takayuki Kunisawa,1 Hiroshi Iwasaki,11Department of Anesthesiology and Critical Care Medicine, Asahikawa Medical University, Asahikawa, 2Department of Anatomy, The Jikei University Graduate School of Medicine, Tokyo, JapanPurpose: The aim of this clinical trial was to investigate changes in stroke volume variability (SVV) and left ventricular end-diastolic volume (LVEDV) after a fluid bolus of crystalloid or colloid using real-time three-dimensional transesophageal echocardiography (3D-TEE) and the Vigileo-FloTrac&trade; system.Materials and methods: After obtaining Institutional Review Board approval, and informed consent from the research participants, 22 patients undergoing scheduled peripheral vascular bypass surgery were enrolled in the study. The patients were randomly assigned to receive 500 mL of hydroxyethyl starch (HES; HES group, n=11) or normal saline (Saline group, n=11) for fluid replacement therapy. …”
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ROLE OF CARDIAC-ANKLE VASCULAR INDEX IN PREDICTION OF LONG TERM ADVERSE OUTCOMES IN PATIENTS WITH NON ST ELEVATION ACUTE CORONARY SYNDROME by S. A. Berns, E. A. Schmidt, О. A. Nagirniak, I. I. Zhidkova, М. N. Litvinova, O. L. Barbarash

“…The following clinical and instrumental parameters are associated with adverse cardiovascular events in NSTEMI patients during 5 year follow-up: older age, anamnesis of myocardial infarction and coronary bypass surgery, ischemic ECG changes, decreased left ventricle ejection fraction, higher GRACE score at admission and CAVI &gt;8,55 by sphygmomanometry. …”
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Safety and Feasibility of the BYCROSS^® Atherectomy Device for the Treatment of Femoropopliteal Arterial Obstructions: Single-Center Short-Term Outcomes by Goudje L. van Leeuwen, Reinoud P. H. Bokkers, Job Oldenziel, Richte C. L. Schuurmann, Cornelis G. Vos, Jean-Paul P. M. de Vries

“…<b>Background:</b> Endovascular techniques have gained preference over peripheral arterial bypass surgery due to their minimally invasive nature; however, endovascular treatments often show limited efficacy in arterial segments with a high atherosclerotic load. …”
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The Influence of Calcification Factors and Endothelial-Dysfunction Factors on the Development of Unstable Atherosclerotic Plaques by Yana V. Polonskaya, Elena V. Kashtanova, Ivan S. Murashov, Aleksei V. Kurguzov, Evgeny V. Sadovski, Nikolay A. Maslatsov, Ekaterina M. Stakhneva, Alexander M. Chernyavskii, Yuliya I. Ragino

“…Methods: We analyzed 44 male patients with coronary atherosclerosis who underwent endarterectomy in coronary arteries during coronary bypass surgery. The endarterectomy material (intima/media) was examined using histological and biochemical methods, and the stability and calcification degree of atherosclerotic plaques were assessed. …”
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Neuroprotective effect of remote ischemic preconditioning in patients undergoing cardiac surgery: A randomized controlled trial by Shouqiang Zhu, Ziyu Zheng, Wenying Lv, Pengrong Ouyang, Jiange Han, Jiaqiang Zhang, Hailong Dong, Chong Lei

“…BackgroundThe neuroprotective effect of remote ischemic preconditioning (RIPC) in patients undergoing elective cardiopulmonary bypass (CPB)-assisted coronary artery bypass graft (CABG) or valvular cardiac surgery remains unclear.MethodsA randomized, double-blind, placebo-controlled superior clinical trial was conducted in patients undergoing elective on-pump coronary artery bypass surgery or valve surgery. Before anesthesia induction, patients were randomly assigned to RIPC (three 5-min cycles of inflation and deflation of blood pressure cuff on the upper limb) or the control group. …”
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Exploring the association between sleep insufficiency and self-reported cardiovascular disease among northeastern Greeks by Petros N. Fountoulakis, Aikaterini Terzoudi, Dimitrios Tsiptsios, Andreas S. Triantafyllis, Anestis Matziridis, Eleni Leontidou, Apostolos Manolis, Konstantinos Tsamakis, Andreas Ouranidis, Paschalis Steiropoulos, Theofanis Vorvolakos, Aspasia Serdari, Gregory Tripsianis

“…CVD was defined by a positive response to the questions: “Have you been told by a doctor that you have had a heart attack or angina or stroke or have you undergone bypass surgery?”. Sleep quality, utilizing Epworth sleepiness scale, Athens insomnia scale, Pittsburgh sleep quality index and Berlin questionnaire, was also examined. …”
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Mesenchymal Stem Cell Transplantation Has a Regenerative Effect in Ischemic Myocardium: An Experimental Rat Model Evaluated by SPECT-CT Assessment by Antonella Koutela, George Loudos, Maritina Rouchota, Dimitrios Kletsas, Andreas Karameris, George Vilaras, George C. Zografos, Despoina Myoteri, Dimitrios Dougenis, Apostolos E. Papalois

“…From a clinical perspective, this work supports the surgical administration of MSCT in the infarcted area during coronary artery bypass surgery. Aims: The regeneration of myocardial tissue and the improvement of myocardial activity after ischemia is one of the major areas of interest in cardiovascular research. …”
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Elderly Suffering from ST-Segment Elevation Myocardial Infarction—Results from a Database Analysis from Two Mediterranean Medical Centers by Leor Perl, Alfonso Franzé, Fabrizio D’Ascenzo, Noa Golomb, Amos Levi, Hana Vaknin-Assa, Gabriel Greenberg, Abid Assali, Gaetano M. De Ferrari, Ran Kornowski

“…At 1 month and 3 years after intervention, mortality was higher in the octogenarian patients (12.2 vs. 7.9%, <i>p</i> = 0.01; and 36.7 vs. 23.1%, <i>p</i> < 0.01, respectively), with no significant differences in the rates of recurrent myocardial infarction, target vessel revascularization, coronary artery bypass surgery, and cardiovascular death. Following adjustment for confounders, 3-year mortality was significantly higher in the octogenarians (HR 3.89 vs. 3.19 for septuagenarians, <i>p</i> < 0.01), but rates of major adverse cardiac events or cardiovascular death were not. …”
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RELATIONSHIP OF MULTIFOCAL ATHEROSCLEROSIS AND RENAL DYSFUNCTION WITH IN-HOSPITAL COMPLICATIONS AFTER CORONARY BYPASS OPERATION IN ISCHEMIC HEART DISEASE by K. S. Shafranskaya, M. V. Zykov, V. V. Kashtalap, O. K. Kuzmina, I. S. Bykova, V. N. Karetnikova, A. N. Sumin, S. V. Ivanov S, O. L. Barbarash

“…To assess the occurence of hemodynamically non-significant multifocal atherosclerosis (from 30% and more), renal dysfunction and their influence on the outcomes of in-hospital period of patients underwent coronary bypass surgery (CABG).Material and methods. The perioperational period of 720 patients analyzed, who were operated in 2011-2012 y. …”
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Long-term follow-up of medically treated patients with spontaneous coronary artery dissection: a prospective, Swiss single-centre cohort study by Sebastian Seidl, Hans Rickli, Sebastian Rogowski, Daniel Weilenmann, Peter Ammann, Philipp K. Haager, Lucas Joerg, Franziska Rohner, Joannis Chronis, Johannes Rigger, Micha T. Maeder

“…Seven patients were treated with percutaneous coronary intervention (PCI) and one patient underwent bypass surgery. Elective follow-up angiograms were performed in 73 asymptomatic patients after a median follow-up of 6.0 months (interquartile range [IQR] 5.5–6.5). …”
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Predictors of complications when transferring postoperative cardiac patients from the intensive care unit by K. V. Paromov, M. Yu. Kirov

“…The increase in fluid balance during ICU stay after off-pump coronary artery bypass surgery tended to result in a complicated postoperative period (AUC = 0.73, p = 0.02) and a higher risk of atrial fibrillation.…”
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