Showing 201 - 220 results of 6,377 for search '"cadherin"', query time: 0.14s Refine Results
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    VE-cadherin-independent cancer cell incorporation into the vascular endothelium precedes transmigration. by Susan M Hamilla, Kimberly M Stroka, Helim Aranda-Espinoza

    Published 2014-01-01
    “…During this phase, cancer cells physically displace ECs, leading to the dislocation of EC VE-cadherin away from EC junctions bordering cancer cells, and spread into the monolayer. …”
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    Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease by Rawan Tarawneh, Rachel S. Kasper, Jessie Sanford, Chia‐Ling Phuah, Jason Hassenstab, Carlos Cruchaga

    Published 2022-12-01
    “…We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD. …”
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  6. 206

    VE-Cadherin modulates β-catenin/TCF-4 to enhance Vasculogenic Mimicry by Daniel Delgado-Bellido, Esteban Zamudio-Martínez, Mónica Fernández-Cortés, Ana Belén Herrera-Campos, Joaquin Olmedo-Pelayo, Carmen Jordán Perez, José Expósito, Enrique de Álava, Ana Teresa Amaral, Francisco O’ Valle, Angel Garcia Diaz, F. J. Oliver

    Published 2023-02-01
    “…Uveal melanoma cells knockout for VE-Cadherin loses β-catenin expression while the rescue of VE-Cadherin (but not of the phosphorylation defective VE-Cadherin Y658F mutant) permits stabilization of β-catenin and tumor growth reduction in vivo experiments. …”
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    ADP-ribosylation factor 6 mediates E-cadherin recovery by chemical chaperones. by Joana Figueiredo, Joana Simões-Correia, Ola Söderberg, Gianpaolo Suriano, Raquel Seruca

    Published 2011-01-01
    “…E-cadherin plays a powerful tumor suppressor role. Germline E-cadherin mutations justify 30% of Hereditary Diffuse Gastric Cancer (HDGC) and missense mutations are found in 30% of these families. …”
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    Loss of Cadherin-11 in pancreatic ductal adenocarcinoma alters tumor-immune microenvironment by Aimy Sebastian, Kelly A. Martin, Ivana Peran, Nicholas R. Hum, Nicole F. Leon, Beheshta Amiri, Stephen P. Wilson, Matthew A. Coleman, Elizabeth K. Wheeler, Stephen W. Byers, Gabriela G. Loots, Gabriela G. Loots

    Published 2023-10-01
    “…The 5-year survival rate for PDAC is 10% following diagnosis. Cadherin 11 (Cdh11), a cell-to-cell adhesion molecule, has been suggested to promote tumor growth and immunosuppression in PDAC, and Cdh11 inhibition significantly extended survival in mice with PDAC. …”
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    Computational evidence for multi-layer crosstalk between the cadherin-11 and PDGFR pathways by Zeynep Karagöz, Fiona R. Passanha, Lars Robeerst, Martijn van Griensven, Vanessa L. S. LaPointe, Aurélie Carlier

    Published 2023-09-01
    “…Recently, cadherin-11, which is a member of the type II classical cadherin family, has been shown to be involved in the fate commitment of hMSCs. …”
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    Vitronectin increases vascular permeability by promoting VE-cadherin internalization at cell junctions. by Rong Li, Meiping Ren, Ni Chen, Mao Luo, Zhuo Zhang, Jianbo Wu

    Published 2012-01-01
    “…Cross-talk between integrins and cadherins regulates cell function. We tested the hypothesis that vitronectin (VN), a multi-functional adhesion molecule present in the extracellular matrix and plasma, regulates vascular permeability via effects on VE-cadherin, a critical regulator of endothelial cell (EC) adhesion.Addition of multimeric VN (mult VN) significantly increased VE-cadherin internalization in human umbilical vein EC (HUVEC) monolayers. …”
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    Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion by Akinobu Senoo, Sho Ito, Satoru Nagatoishi, Yutaro Saito, Go Ueno, Daisuke Kuroda, Kouhei Yoshida, Takumi Tashima, Shota Kudo, Shinsuke Sando, Kouhei Tsumoto

    Published 2021-09-01
    “…Senoo et al. describe a chemical fragment that disrupts dimerization of P-cadherin. In doing so, this fragment inhibits cadherin-mediated cell-adhesion and aggregation.…”
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