Post-treatment With Qing-Ying-Tang, a Compound Chinese Medicine Relives Lipopolysaccharide-Induced Cerebral Microcirculation Disturbance in Mice by Hao-Min Wang, Hao-Min Wang, Hao-Min Wang, Hao-Min Wang, Hao-Min Wang, Hao-Min Wang, Ping Huang, Ping Huang, Ping Huang, Ping Huang, Ping Huang, Quan Li, Quan Li, Quan Li, Quan Li, Quan Li, Lu-Lu Yan, Lu-Lu Yan, Lu-Lu Yan, Lu-Lu Yan, Lu-Lu Yan, Kai Sun, Kai Sun, Kai Sun, Kai Sun, Kai Sun, Li Yan, Li Yan, Li Yan, Li Yan, Li Yan, Chun-Shui Pan, Chun-Shui Pan, Chun-Shui Pan, Chun-Shui Pan, Chun-Shui Pan, Xiao-Hong Wei, Xiao-Hong Wei, Xiao-Hong Wei, Xiao-Hong Wei, Xiao-Hong Wei, Yu-Ying Liu, Yu-Ying Liu, Yu-Ying Liu, Yu-Ying Liu, Yu-Ying Liu, Bai-He Hu, Bai-He Hu, Bai-He Hu, Bai-He Hu, Bai-He Hu, Chuan-She Wang, Chuan-She Wang, Chuan-She Wang, Chuan-She Wang, Chuan-She Wang, Chuan-She Wang, Jing-Yu Fan, Jing-Yu Fan, Jing-Yu Fan, Jing-Yu Fan, Jing-Yu Fan, Jing-Yan Han, Jing-Yan Han, Jing-Yan Han, Jing-Yan Han, Jing-Yan Han, Jing-Yan Han

“…QYT ameliorated the downregulation of claudin-5, occludin, JAM-1, ZO-1, collagen IV as well as the expression and phosphorylation of VE-cadherin in mouse brain.Conclusions: This study demonstrated that QYT protected cerebral microvascular barrier from disruption after LPS by acting on the transcellular pathway mediated by caveolae and paracellular pathway mediated by junction proteins. …”
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Chinese medicine Fufang Zhenzhu Tiaozhi capsule ameliorates coronary atherosclerosis in diabetes mellitus-related coronary heart disease minipigs by Lexun Wang, Dongxing Zhang, Wenjing Zhan, Zhihuan Zeng, Jianying Yin, Ke Wang, Hong Wang, Lixia Song, Zhanhui Gu, Caijuan Guo, Qin Zhong, Weixuan Wang, Xianglu Rong, Weijian Bei, Jiao Guo

“…In addition, IκB and NF-κB phosphorylation levels, as well as the protein levels of IL-1β, Bax, cleave-Caspase 3, Bcl-2, and α-SMA were dramatically increased in the DM-CHD coronary artery, whereas CD31 and VE-cadherin expressions were decreased. Similar to M+A, FTZ reversed these protein levels in the DM-CHD coronary artery. …”
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Induction of differentiation inhibits the tumorigenic potential of glioblastoma cancer stem cells by F. M. Brehar, A. V. Ciurea, R. M. Gorgan, Coralia Bleotu, A. Tascu, R. I. Radulescu, Lilia Matei, Otilia Zarnescu

“…The expression of MMPs, cadherins and cadherins decreased after exposure of the CSCs cultures to the differentiation inductor factors. …”
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Spatio-temporally restricted expression of cell adhesion molecules during chicken embryonic development. by Priti Roy, Amitabha Bandyopadhyay

“…Differential cell adhesive properties are known to regulate important developmental events like cell sorting and cell migration. Cadherins and protocadherins are known to mediate these cellular properties. …”
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Distance-dependent adhesion of vascular cells on biofunctionalized nanostructures by Biela Sarah, Striegl Britta, Frey Kerstin, Spatz Joachim P., Kemkemer Ralf

“…To investigate molecular details of cell-ECM and cadherins (cell-cell) interaction in vascular cells functional nanostructured surfaces were used Ligand-functionalized gold nanoparticles (AuNPs) with 6-8 nm diameter, are precisely immobilized on a surface and separated by non-adhesive regions so that individual integrins or cadherins can specifically interact with the ligands on the AuNPs. …”
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Implications of normal and disordered remodeling dynamics of corneodesmosomes in stratum corneum by Yasuo Kitajima

“…These junctions are connected directly with transmembrane desmosomal cadherins, desmogleins (Dsgs), and desmocollins (Dscs); mainly Dsg1/Dsc1 and Dsg3/Dsc3 in desmosomes, and Dsg1/Dsc1 with corneodesmosin in corneodesmosomes. …”
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The Dachsous/Fat/Four-Jointed Pathway Directs the Uniform Axial Orientation of Epithelial Cells in the Drosophila Abdomen by Federica Mangione, Enrique Martín-Blanco

“…The refinement of the tissue-wide expression of the atypical cadherins Ds and Ft result in their polarization and directional adhesiveness. …”
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Single-molecule force spectroscopy reveals the dynamic strength of the hair-cell tip-link connection by Eric M. Mulhall, Andrew Ward, Darren Yang, Mounir A. Koussa, David P. Corey, Wesley P. Wong

“…Here authors show that a single tip-link bond is more mechanically stable relative to classic cadherins, and that the double stranded tip-link connection is stabilized by single strand rebinding facilitated by strong cis-dimerization domains.…”
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Rabconnectin-3a regulates vesicle endocytosis and canonical Wnt signaling in zebrafish neural crest migration. by Adam M Tuttle, Trevor L Hoffman, Thomas F Schilling

“…We propose that Rbc3a and Atp6v0a1 promote endosomal maturation to coordinate Wnt signaling and intracellular trafficking of Wnt receptors and cadherins required for NC migration and cell fate determination. …”
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miR-195-5p as Regulator of γ-Catenin and Desmosome Junctions in Colorectal Cancer by Emanuele Piccinno, Viviana Scalavino, Raffaele Armentano, Gianluigi Giannelli, Grazia Serino

“…JUP closely interacts with desmosomal cadherins, and downstream, it regulates several intracellular transduction factors. …”
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Current ideas about molecular genetic subtypes of ovarian cancer: a personalized approach and a new platform for further research by A. Rybin

“…The mesenchymal subtype C5 is widely represented by mesenchymal cells, characterized by overexpression of N-cadherins and P-cadherins, low expression of differentiation markers and lower survival than C2 and C4. …”
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Cell adhesion molecules in the pathogenesis of the schizophrenia by Antonino Messina, Caterina Crescimanno, Giuseppe Cuccì, Filippo Caraci, Maria Salvina Signorelli

“…Among the CAMs, several families have been identified, such as integrins, selectins, cadherins, immunoglobulins, nectins, and the neuroligin-neurexin complex. …”
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A STUDY OF TUMOR-ASSOCIATED PROTEINS IN TISSUES AND BLOOD SERA FROM BREAST CANCER PATIENTS by T. S. Bobrova, Yu. V. Chuev

“…The proteins may be associated either with cathepsin D precursors, or mucins, or cadherins, or CD22 adhesion molecule.…”
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Cardiac desmosomal adhesion relies on ideal-, slip- and catch bonds by Manuel Göz, Sylvia M. Steinecker, Greta M. Pohl, Volker Walhorn, Hendrik Milting, Dario Anselmetti

“…Desmosomal adhesion is mediated by densely packed and organized cadherins which, in presence of Ca2+, stretch out their extracellular domains (EC) and dimerize with opposing binding partners by exchanging an N-terminal tryptophan. …”
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Conserved expression of vertebrate microvillar gene homologs in choanocytes of freshwater sponges by Jesús F. Peña, Alexandre Alié, Daniel J. Richter, Lingyu Wang, Noriko Funayama, Scott A. Nichols

“…Possible exceptions include the cadherins that form intermicrovillar links in the enterocyte brush border and hair cell stereocilia of vertebrates and cnidarians. …”
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Nck2 promotes human melanoma cell proliferation, migration and invasion <it>in vitro </it>and primary melanoma-derived tumor growth <it>in vivo</it> by Picard-Cloutier Aude, Ismaïl Salma, Dusseault Julie, Labelle-Côté Mélissa, Siegel Peter M, Larose Louise

“…By western blot analysis, we compared levels of proteins phosphorylated on tyrosine as well as cadherins and integrins in human melanoma cells overexpressing or not Nck2. …”
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Physicochemical Principles of Adhesion Mechanisms in the Brain by Katarzyna Stachowicz

“…Cell adhesion molecules (CAMs) such as cadherins, integrins, selectins, and immunoglobulin family of cell adhesion molecules (IgSF) will be discussed, and their role in physiological and pathological brain function. …”
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Mechanisms of Cell Adhesion Molecules in Endocrine-Related Cancers: A Concise Outlook by Yongsheng Ruan, Libai Chen, Danfeng Xie, Tingting Luo, Yiqi Xu, Tao Ye, Xiaona Chen, Xiaoqin Feng, Xuedong Wu

“…To understand these mechanisms, this review focuses on the role of CD44, cadherins, selectins, and integrins in CAM-DR in endocrine-related cancers.…”
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Role of TRIM16 in cancers development by L. V. Spirina, I. V. Kondakova, N. V. Tarasenko

“…The TRIM16 protein acts the proteins TPD43, Gli-1, RARβ, Snail components and MAPK signaling pathway, cadherins, caspases and is also associated with the regulation  of the immune system via direct and indirect mechanisms. …”
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The molecular structure of cell adhesion molecules. by Chothia, C, Jones, E

“…Considerable advances have been made in our knowledge of the molecular structure of cell adhesion molecules, their binding sites, and adhesion complexes. For the cadherins, protein zero, and CD2, additional experimental data support the insights obtained from structural analysis of their domains and molecular models of their adhesion complexes. …”