ADAM10: Possible functions in enamel development by Shifa Shahid, Atsushi Ikeda, Michelle C. Layana, John D. Bartlett

“…ADAM10 may play an important role in enamel development. ADAM10 can cleave cadherins and other cell-cell junctions at specific sites where the tetraspanins have transported it and this may promote cell movement. …”
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Structural insights into SraP-mediated Staphylococcus aureus adhesion to host cells. by Yi-Hu Yang, Yong-Liang Jiang, Juan Zhang, Lei Wang, Xiao-Hui Bai, Shi-Jie Zhang, Yan-Min Ren, Na Li, Yong-Hui Zhang, Zhiyong Zhang, Qingguo Gong, Yide Mei, Ting Xue, Jing-Ren Zhang, Yuxing Chen, Cong-Zhao Zhou

“…The second module adopts a β-grasp fold similar to Ig-binding proteins, whereas the last two tandem repetitive modules resemble eukaryotic cadherins but differ in calcium coordination pattern. …”
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The desmosomal armadillo protein plakoglobin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signaling. by Carrie A Franzen, Viktor Todorović, Bhushan V Desai, Salida Mirzoeva, Ximing J Yang, Kathleen J Green, Jill C Pelling

“…Plakoglobin (PG) is an armadillo protein that associates with both classic and desmosomal cadherins, but is primarily concentrated in mature desmosomes in epithelia. …”
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Potential Immunohistochemical Biomarkers for Grading Oral Dysplasia: A Literature Review by Jakub Zdrojewski, Monika Nowak, Kacper Nijakowski, Jakub Jankowski, Andrea Scribante, Simone Gallo, Maurizio Pascadopoli, Anna Surdacka

“…Some analysed biomarkers are most frequently chosen, such as p53, Ki-67, cadherins/catenins, and other proteins used to differentiate OED grades. …”
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Adhesion Percolation Determines Global Deformation Behavior in Biomimetic Emulsions by Lorraine Montel, Iaroslava Golovkova, Silvia Grigolon, Elie Wandersman, Alexis M. Prevost, Thibault Bertrand, Lea-Laetitia Pontani

“…In particular, the intercellular adhesion forces, mediated by transmembrane proteins like cadherins, are expected to control the topology and viscoelastic behavior of tissues under mechanical stress. …”
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Antiproliferative and Proapoptotic Effects of Erucin, a Diet-Derived H₂S Donor, on Human Melanoma Cells by Daniela Claudia Maresca, Lia Conte, Benedetta Romano, Angela Ianaro, Giuseppe Ercolano

“…The proapoptotic effect of ERU was associated with the modulation of the epithelial-to-mesenchymal transition (EMT)-related cadherins and transcription factors. Moreover, ERU thwarted the migration, invasiveness and clonogenic abilities of A375 melanoma cells. …”
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Solution NMR Determination of the CDHR3 Rhinovirus-C Binding Domain, EC1 by Woonghee Lee, Ronnie O. Frederick, Marco Tonelli, Ann C. Palmenberg

“…Cadherin Related Family Member 3 (CDHR3) is the identified and required cellular receptor for all virus isolates in the rhinovirus-C species (RV-C). …”
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The role of ubiquitination and deubiquitination in the regulation of cell junctions by Junting Cai, Miranda K. Culley, Yutong Zhao, Jing Zhao

“…Ubiquitination and degradation of cadherins, claudins, and their interacting proteins are implicated in epithelial and endothelial barrier disruption. …”
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Multiple Known Mechanisms and a Possible Role of an Enhanced Immune System in Bt-Resistance in a Field Population of the Bollworm, <i>Helicoverpa zea</i>: Differences in Gene Expre... by Roger D. Lawrie, Robert D. Mitchell III, Jean Marcel Deguenon, Loganathan Ponnusamy, Dominic Reisig, Alejandro Del Pozo-Valdivia, Ryan W. Kurtz, R. Michael Roe

“…We found expected gene expression differences based on our current understanding of the Bt mode of action, including increased expression of proteases (trypsins and serine proteases) and reduced expression of Bt-interacting receptors (aminopeptidases and cadherins) in resistant bollworms. We also found additional expression differences for transcripts that were not previously investigated, i.e., transcripts from three immune pathways-Jak/STAT, Toll, and IMD. …”
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New Gene Markers of Exosomal Regulation Are Involved in Porcine Granulosa Cell Adhesion, Migration, and Proliferation by Jakub Kulus, Wiesława Kranc, Magdalena Kulus, Dorota Bukowska, Hanna Piotrowska-Kempisty, Paul Mozdziak, Bartosz Kempisty, Paweł Antosik

“…The complexity of intercellular interactions in the ovarian follicle is also based on multilevel intercellular signaling, including the mechanisms involving cadherins, integrins, and the extracellular matrix. …”
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Mechanisms of the Osteogenic Switch of Smooth Muscle Cells in Vascular Calcification: WNT Signaling, BMPs, Mechanotransduction, and EndMT by John Tyson, Kaylee Bundy, Cameron Roach, Hannah Douglas, Valerie Ventura, Mary Frances Segars, Olivia Schwartz, C. LaShan Simpson

“…In a pro-calcific environment, integrins and cadherins of vascular smooth muscle cells respond to a mechanical stimulus, activating cellular signaling pathways, ultimately resulting in gene regulation that promotes calcification of the vascular extracellular matrix (ECM). …”
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Transgenic insect-resistant Bt cotton expressing Cry1Ac/1Ab does not harm the insect predator Geocoris pallidipennis by Meng Zhang, Yamin Ma, Junyu Luo, Jichao Ji, Xueke Gao, Changcai Wu, Xiangzhen Zhu, Li Wang, Kaixin Zhang, Dongyang Li, Lisha Wang, Lin Niu, Jinjie Cui

“…Furthermore, G. pallidipennis cadherins, and those genes related to detoxification, antioxidant activity, nutrient utilization, and immune function were not differentially expressed in response to Cry1Ac exposure. …”
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Preventive effect of celecoxib use against cancer progression and occurrence of oral squamous cell carcinoma by Shang-Lun Chiang, Bharath Kumar Velmurugan, Chia-Min Chung, Shu-Hui Lin, Zhi-Hong Wang, Chun-Hung Hua, Ming-Hsui Tsai, Tzer-Min Kuo, Kun-Tu Yeh, Pei-Ying Chang, Yi-Hsin Yang, Ying-Chin Ko

“…The in-vitro findings showed that CXB is involved in the inhibition of EMT and cell mobility through blocking transcription factors (Slug, Snail and ZEB1), cytoplasmic mediators (focal adhesion kinase (FAK), vimentin and β-catenin), cell adhesion molecules (cadherins and integrins), and surface receptors (AMFR and EGFR). …”
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Modulation of cell-cell interactions for neural tissue engineering : potential therapeutic applications of cell adhesion molecules in nerve regeneration by Chooi, Wai Hon, Chew, Sing Yian

“…Therefore, modulating cell-cell interactions through cell adhesion molecules (CAMs) such as cadherins, neural cell adhesion molecules (NCAM) and L1, may be a potential alternative to improve nerve regeneration. …”
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Preclinical studies identify non-apoptotic low-level caspase-3 as therapeutic target in pemphigus vulgaris. by Camille Luyet, Katja Schulze, Beyza S Sayar, Denise Howald, Eliane J Müller, Arnaud Galichet

“…The disease is caused by auto-antibodies that bind to desmosomal cadherins desmoglein (Dsg) 3 or Dsg3 and Dsg1 in mucous membranes and skin. …”
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Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities by Simpson David A, Gardiner Tom A, Guduric-Fuchs Jasenka, Sweeney Mark, O'Neill Christina L, Medina Reinhold J, Stitt Alan W

“…In line with the expression pattern of caveolins and cadherins identified by microarray analysis, ultrastructural evaluation highlighted the presence of caveolae and adherens junctions only in OECs.…”
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A Subset of Autism-associated Genes Regulate the Structural Stability of Neurons by Yu-Chih Lin, Jeannine A Frei, Michaela B.C. Kilander, Wenjuan Shen, Gene J Blatt

“…We sub-categorize them into 1) cytoskeletal regulators, e.g. motors and small RhoGTPase regulators; 2) adhesion molecules, e.g. cadherins, NCAM, and neurexin superfamily; 3) cell surface receptors, e.g. glutamatergic receptors and receptor tyrosine kinases; 4) signaling molecules, e.g. protein kinases and phosphatases; and 5) synaptic proteins, e.g. vesicle and scaffolding proteins. …”
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The Src-Family Kinases SRC and BLK Contribute to the CLDN6-Adhesion Signaling by Naoki Ichikawa-Tomikawa, Kotaro Sugimoto, Korehito Kashiwagi, Hideki Chiba

“…Cell adhesion molecules, including integrins, cadherins, and claudins (CLDNs), are known to activate Src-family kinases (SFKs) that organize a variety of physiological and pathological processes; however, the underlying molecular basis remains unclear. …”
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LIC12254 Is a Leptospiral Protein That Interacts with Integrins via the RGD Motif by Maria F. Cavenague, Aline F. Teixeira, Luis G. V. Fernandes, Ana L. T. O. Nascimento

“…Pathogenic leptospires can bind to receptors on mammalian cells such as cadherins and integrins. <i>Leptospira</i> effectively adheres to cells, overcomes host barriers and spreads into the bloodstream, reaching internal target organs such as the lungs, liver and kidneys. …”
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Cancer as a channelopathy: ion channels and pumps in tumor development and progression by Alisa eLitan, Alisa eLitan, Sigrid A Langhans

“…This process is triggered and modulated by a combination of environmental signals, which are sensed and integrated by membrane receptors, including integrins and cadherins. Membrane receptors transduce these signals into downstream signaling pathways, often involving the Rho GTPase protein family. …”
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