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Hubbing the Cancer Cell
Published 2022-11-01“…Oncogenic transformation drives adaptive changes in a growing tumor that affect the cellular organization of cancerous cells, resulting in the loss of specialized cellular functions in the polarized compartmentalization of cells. …”
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Phosphorylated Osteopontin Secreted from Cancer Cells Induces Cancer Cell Motility
Published 2021-09-01“…Osteopontin (OPN) plays a pivotal role in cancer cell invasion and metastasis. Although OPN has a large number of phosphorylation sites, the functional significance of OPN phosphorylation in cancer cell motility remains unclear. …”
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Label-free microfluidic enrichment of cancer cells from non-cancer cells in ascites
Published 2021-09-01“…Abstract The isolation of a patient's metastatic cancer cells is the first, enabling step toward treatment of that patient using modern personalized medicine techniques. …”
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Dormant cancer cells and polyploid giant cancer cells: The roots of cancer recurrence and metastasis
Published 2024-02-01Subjects: Get full text
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Immunosurveillance of cancer cell stress
Published 2019-07-01“…Nonetheless, certain immune subsets, such as tumor-associated macrophages, have been described to promote tumor growth, unraveling a double-edge role of the immune system in cancer. Cell stress can modulate the crosstalk between immune cells and tumor cells, reshaping tumor immunogenicity and/or immune function and phenotype. …”
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Biomechanical Properties of Cancer Cells
Published 2021-04-01“…Since the crucial role of the microenvironment has been highlighted, many studies have been focused on the role of biomechanics in cancer cell growth and the invasion of the surrounding environment. …”
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Hyaluronan in the Cancer Cells Microenvironment
Published 2023-01-01“…Hyaluronan has an effect on all cancer cell behaviors, such as evasion of apoptosis, limitless replicative potential, sustained angiogenesis, and metastasis. …”
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Glutathione in Cancer Cell Death
Published 2011-03-01“…Glutathione (L-γ-glutamyl-L-cysteinyl-glycine; GSH) in cancer cells is particularly relevant in the regulation of carcinogenic mechanisms; sensitivity against cytotoxic drugs, ionizing radiations, and some cytokines; DNA synthesis; and cell proliferation and death. …”
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Metabolic features of cancer cells
Published 2018-10-01“…Abstract Cancer cells uniquely reprogram their cellular activities to support their rapid proliferation and migration and to counteract metabolic and genotoxic stress during cancer progression. …”
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Autophagy in Cancer Cell Death
Published 2019-10-01“…An alternative pro-death function of autophagy has been consistently observed in different settings, in particular, in developmental cell death of lower organisms and in drug-induced cancer cell death. This cell death is referred to as autophagic cell death (ACD) or autophagy-dependent cell death (ADCD), a type of cellular demise that may act as a backup cell death program in apoptosis-deficient tumors. …”
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Acetate metabolism in cancer cells
Published 2014“…Studies examining the nutrients used by cancer cells have focused on the contribution of glucose and glutamine carbon for biosynthesis, but the importance of other metabolic fuels is becoming apparent. …”
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Cancer Cell Image Segregation
Published 2006“…However, some weakness we face must be solved in order to obtain the accurate data from medical image such as image of breast cancer cells that is overlapping of cell image in cluster will affect the data. …”
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The Effect of Hyperthermia and Radiotherapy Sequence on Cancer Cell Death and the Immune Phenotype of Breast Cancer Cells
Published 2022-04-01“…However, currently little is known about how HT with a distinct temperature, and particularly, how the sequence of HT and RT changes the immune phenotype of breast cancer cells. Therefore, human MDA-MB-231 and MCF-7 breast cancer cells were treated with HT of different temperatures (39, 41 and 44 °C), alone and in combination with RT (2 × 5 Gy) in different sequences, with either RT or HT first, followed by the other. …”
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Exosomal Long Non-Coding RNA: Interaction Between Cancer Cells and Non-Cancer Cells
Published 2021-01-01“…Besides, we provided an overview of current research on functions of exosomal lncRNAs between cancer cells and non-cancer cells. A deep understanding of exosomal lncRNAs’ role in cancer will be facilitated to find important implications for cancer development and treatment.…”
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Umbelliprenin induces autophagy and apoptosis while inhibits cancer cell stemness in pancreatic cancer cells
Published 2023-07-01“…Umbelliprenin also reduced pancreatic cancer cell stemness by reducing Oct4, Nanog, and Sox2 mRNA levels (p < 0.01). …”
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Cancer cell sensitivity to bortezomib is associated with survivin expression and p53 status but not cancer cell types
Published 2010-01-01“…</p> <p>Results</p> <p>We found that cancer cells with wild type p53 show a low level expression of survivin and are sensitive to treatment with bortezomib, while cancer cells with a mutant or null p53 show a high level expression of survivin and are resistant to bortezomib-mediated apoptosis induction. …”
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Akt-Activated Endothelium Increases Cancer Cell Proliferation and Resistance to Treatment in Ovarian Cancer Cell Organoids
Published 2022-11-01“…Ovarian cancer (OC) is a heterogeneous disease characterized by its late diagnosis (FIGO stages III and IV) and the importance of abdominal metastases often observed at diagnosis. Detached ovarian cancer cells (OCCs) float in ascites and form multicellular spheroids. …”
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