Adjuvant chemotherapy and survival outcomes in rectal cancer patients with good response (ypT0-2N0) after neoadjuvant chemoradiotherapy and surgery: A retrospective nationwide anal... by Yu-Hsuan Kuo, Yu-Hsuan Kuo, Yun-Tzu Lin, Chung-Han Ho, Chung-Han Ho, Chia-Lin Chou, Chia-Lin Chou, Li-Chin Cheng, Chia-Jen Tsai, Wei-Ju Hong, Yi-Chen Chen, Ching-Chieh Yang, Ching-Chieh Yang

“…In this study, we aim to determinate the survival benefit of adjuvant chemotherapy for rectal cancer patients with good response (ypT0-2N0) after nCRT and surgery.MethodsThe study cohort included 720 rectal cancer patients who had good response (ypT0-2N0) after nCRT and surgery, who did or did not receive adjuvant chemotherapy between January 2007 and December 2017, from the Taiwan Cancer Registry and National Health Insurance Research database. …”
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Pancreatic cancer incidence and mortality trends in urban Shanghai, China from 1973 to 2017: a joinpoint regression and age-period-cohort analysis by Mengyin Wu, Kai Gu, Yangming Gong, Chunxiao Wu, Yi Pang, Wei Zhang, Chunfang Wang, Yan Shi, Yingbin Liu, Chen Fu, Chen Fu

“…Background and purposeTo provide a comprehensive overview of epidemiological features and temporal trends of pancreatic cancer in urban Shanghai from 1973 to 2017.MethodsData on pancreatic cancer in urban Shanghai were obtained through the Shanghai Cancer Registry and the Vital Statistics System. Joinpoint analysis was used to describe the temporal trends and annual percent changes (APCs) and age-period-cohort analysis were used to estimate the effects of age, period, and birth cohort on pancreatic cancer.ResultsThere were a total of 29,253 cases and 27,105 deaths of pancreatic cancer in urban Shanghai over the 45-year study period. …”
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Analysis and prediction of 5-year survival in patients with cutaneous melanoma: a model-based period analysis by Suzheng Zheng, Hai Yu, Xinkai Zheng, U Tim Wu, Wai-kit Ming, Hui Huang, Jiaxin Song, Xiaoxi Zhang, Jun Lyu, Jun Lyu, Liehua Deng, Liehua Deng

“…This study used population-based cancer registry data to examine the 5-year relative survival rate of CM in the US.MethodsPeriod analysis was used to assess the relative survival rate and trends of patients with CM in the Surveillance, Epidemiology, and End Results (SEER) database during 2004–2018. …”
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Predictive value of abnormal blood tests for detecting cancer in primary care patients with nonspecific abdominal symptoms: A population-based cohort study of 477,870 patients in E... by Rafiq, M, Renzi, C, White, B, Zakkak, N, Nicholson, B, Lyratzopoulos, G, Barclay, M

“…Methods and findings: Using data from the UK Clinical Practice Research Datalink (CPRD) linked to the National Cancer Registry, Hospital Episode Statistics and Index of Multiple Deprivation, we conducted a population-based cohort study of patients aged ≥30 presenting to English general practice with abdominal pain or bloating between January 2007 and October 2016. …”

Development and internal-external validation of statistical and machine learning models for breast cancer prognostication: cohort study by Clift, AK, Dodwell, D, Lord, S, Petrou, S, Brady, M, Collins, GS, Hippisley-Cox, J

“…<br><strong> Setting </strong>QResearch primary care database in England, with individual level linkage to the national cancer registry, Hospital Episodes Statistics, and national mortality registers. …”

Cytotoxicity and mechanisms of action of Zerumbone-loaded nanostructured lipid carrier in triple negative breast cancer cells, MDA-MB-231 by Hosseinpour, Mahnaz

“…According to the Malaysian National Cancer Registry (2006), breast cancer is one of the five most common cancers amongst Malaysian women. …”
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Cytotoxicity and apoptosis effects of curcumin analogue (2E,6E)-2,6-Bis(2,3-Dimethoxybenzylidine) cyclohexanone (DMCH) on human colon cancer cells HT29 and SW620 in vitro by Nurul Fattin, Che Rahim, Yazmin, Hussin, Muhammad Nazirul Mubin, Aziz, Nurul Elyani, Mohamad, Yeap, Swee Keong, Mas Jaffri, Masarudin, Rasedee, Abdullah, Akhtar, M. N., Noorjahan Banu, Alitheen

“…According to the Malaysian National Cancer Registry Report 2012-2016, colorectal cancer was the second most common cancer in Malaysia after breast cancer. …”
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The Use of Optimal Treatment for DLBCL Is Improving in All Age Groups and Is a Key Factor in Overall Survival, but Non-Clinical Factors Influence Treatment by Nicole Wong Doo, Victoria M. White, Kara Martin, Julie K. Bassett, H. Miles Prince, Simon J. Harrison, Michael Jefford, Ingrid Winship, Jeremy L. Millar, Roger L. Milne, John F. Seymour, Graham G. Giles

“…<i>Methods</i>: DLBCL cases were identified through the population-based Victorian Cancer Registry, capturing new diagnoses for two time periods: 2008&#8722;2009 and 2012&#8722;2013. …”
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Survival following hospitalization with hepatocellular carcinoma among people notified with hepatitis B or C virus in Australia (2000‐2014) by Reem Waziry, Jason Grebely, Janaki Amin, Maryam Alavi, Behzad Hajarizadeh, Jacob George, Gail V. Matthews, Matthew Law, Gregory J. Dore

“…Data on HBV (n = 54,399) and HCV (n = 96,908) notifications (1993‐2012) were linked to a hospitalization database (July 2000‐June 2014), the New South Wales Cancer Registry, and the New South Wales Death Registry. …”
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Effect of HPV vaccination and cervical cancer screening in England by ethnicity: a modelling study by Helen C Johnson, MSc, Erin I Lafferty, PhD, Rosalind M Eggo, PhD, Karly Louie, PhD, Kate Soldan, PhD, Jo Waller, PhD, W John Edmunds, PhD

“…Methods: We developed an individual-based model of HPV transmission and disease, parameterising it with the latest data for sexual behaviour (from National Survey of Sexual Attitudes and Lifestyles [Natsal-3]) and vaccine and screening uptake by ethnicity (from Public Health England [PHE]) and fitting it to data for HPV prevalence (from ARTISTIC, PHE, Natsal-3) and HPV-related disease incidence (from National Cancer Registry [ONS]). The outcome of interest was the age-adjusted incidence of HPV-related cancer (both cervical and non-cervical) in all women in England in view of differences and changes in vaccination and screening uptake by ethnicity in England, over time. …”
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Measured weight loss as a precursor to cancer diagnosis: retrospective cohort analysis of 43 302 primary care patients by Brian David Nicholson, Matthew James Thompson, Frederick David Richard Hobbs, Matthew Nguyen, Julie McLellan, Beverly Green, Jessica Chubak, Jason Lee Oke

“…Methods Retrospective cohort study of primary care electronic health records data linked to the Surveillance, Epidemiology, and End Results cancer registry (Integrated healthcare delivery system in Washington State, United States). …”
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Barriers to early diagnosis of cervical cancer: a mixed-method study in Côte d’Ivoire, West Africa by Marie K. Plaisy, Simon P. Boni, Patrick A. Coffie, Aristophane Tanon, Adoubi Innocent, Apollinaire Horo, François Dabis, Anne Bekelynck, Antoine Jaquet, for the IeDEA West Africa Collaboration

“…Information on socio-demographic and history of the disease was extracted from a rapid case ascertainement study performed by the cancer registry of Côte d’Ivoire that enrolled all women diagnosed with cervical cancer between July 2018 and June 2019. …”
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Gastric and duodenal cancer in individuals with Lynch syndrome: a nationwide cohort studyResearch in context by Irene A. Caspers, Ellis L. Eikenboom, Marta Lopez-Yurda, Nicole C.T. van Grieken, Tanya M. Bisseling, Evelien Dekker, Barbara A.J. Bastiaansen, Annemieke Cats, Monique E. van Leerdam

“…Methods: For this retrospective nationwide cohort study, clinical data of individuals with LS registered at the Dutch Hereditary Cancer Registry were matched with pathology reports filed by the Dutch Pathology registry. …”
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A Real-World Evidence Study Using Alberta-Population-Based Data to Describe Treatment Patterns for Metastatic Castration-Sensitive Prostate Cancer Patients (AWARENESS) by Safiya Karim, Jennifer Lowther, Gabriel Gyulay, Dylan O’Sullivan, Christopher J. D. Wallis, Steven M. Yip, Darren R. Brenner, Devon J. Boyne, Winson Y. Cheung

“…Data were obtained from the Alberta Cancer Registry. Patients were assigned to an ADT-alone cohort or a treatment intensification cohort (cohorts 2–5). …”
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Malignant extracranial germ cell tumors in the Netherlands between 1990 and 2018: Stable incidence and improved survival by Caroline C.C. Hulsker, Maya Schulpen, Annelies M.C. Mavinkurve-Groothuis, Otto Visser, József Zsiros, Marc H.W. Wijnen, Ronald R. de Krijger, Annette H. Bruggink, Leendert H.J. Looijenga, Henrike E. Karim-Kos, Alida F.W. van der Steeg

“…Methods: All malignant extracranial GCTs diagnosed in patients aged 0–18 years between 1990 and 2018 were selected from the Netherlands Cancer Registry. Incidence rates were calculated as the average annual number of cases per 1 million person-years. …”
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The role of postoperative adjuvant radiotherapy in local recurrence risk in medullary thyroid carcinoma by Aleksandra Kukulska, Jolanta Krajewska, Zofia Kolosza, Ewa Paliczka-Cieslik, Aleksandra Kropinska, Agnieszka Pawlaczek, Zbigniew Puch, Kornelia Ficek, Teresa Lisik, Dorota Sygula, Zbigniew Wygoda, Jozef Roskosz, Jerzy Wydmanski, Barbara Jarzab

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The impact of national holidays on postoperative radiotherapy of squamous cell carcinoma of the head and neck by Michael S. Kim, Margaret Sheridan, Murali Rajaraman, Helmut Hollenhorst, Amanda Caissie, Ashraf Mahmoud-Ahmed, Nathan Lamond, Stephanie Snow, Martin Corsten, S. Mark Taylor, Jonathan R.B. Trites, Matthew H. Rigby, Martin Bullock, Derek Wilke

“…Methods: The provincial cancer registry was queried to obtain demographic, pathologic, and outcomes data from cancer patients treated for all squamous cell carcinomas of the head and neck region treated between January 1, 2007 and November 30, 2019. …”
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Oral uracil–tegafur compared with intravenous chemotherapy as adjuvant therapy for resected early‐stage non‐small cell lung cancer patients by Sheng‐Kai Liang, Chang‐Wei Wu, Ching‐I Chang, Li‐Ta Keng, Meng‐Rui Lee, Jann‐Yuan Wang, Jen‐Chung Ko, Wei‐Yu Liao, Kuan‐Yu Chen, Chao‐Chi Ho, Jin‐Yuan Shih, Chong‐Jen Yu

“…Methods From January 2011 to December 2017, patients with early‐stage NSCLC (defined as tumor size >3 cm without mediastinal lymph node involvement or any distant metastasis) receiving either adjuvant oral UFT or intravenous chemotherapy after surgical resection were identified from the Taiwan Cancer Registry. Overall survival (OS) and relapse‐free survival (RFS) were the primary and secondary outcomes, respectively. …”
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Changes in the Number of Gastrointestinal Cancers and Stage at Diagnosis with COVID-19 Pandemic in Japan: A Multicenter Cohort Study by Kento Kuzuu, Noboru Misawa, Keiichi Ashikari, Shigeki Tamura, Shingo Kato, Kunihiro Hosono, Masato Yoneda, Takashi Nonaka, Shozo Matsushima, Tatsuji Komatsu, Atsushi Nakajima, Takuma Higurashi

“…This retrospective cohort study compared the number of newly diagnosed patients, stage at diagnosis, and detection process of gastrointestinal cancers based on hospital-based cancer registry data at two tertiary Japanese hospitals. …”
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Circulating tumor DNA as prognostic markers of relapsed breast cancer: a systematic review and meta-analysis by Na'na Guo, Qingxin Zhou, Xiaowei Chen, Baoqi Zeng, Shanshan Wu, Hongmei Zeng, Feng Sun

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