Long-Term Survival in Patients with Oligometastatic Non-Small Cell Lung Cancer by a Multimodality Treatment—Comparison with Stage III Disease by Maja Guberina, Christoph Pöttgen, Nika Guberina, Christian Hoffmann, Marcel Wiesweg, Cedric Richlitzki, Martin Metzenmacher, Clemens Aigner, Servet Bölükbas, Thomas Gauler, Wilfried E. E. Eberhardt, Michael Forsting, Ken Herrmann, Dirk Theegarten, Kaid Darwiche, Verena Jendrossek, Martin Stuschke, Martin Schuler

Get full text

Multi-omics reveals specific host metabolism-microbiome associations in intracerebral hemorrhage by Lei Chen, Sai Wang, Yupeng Zhang, Ye Li, Xiangbin Zhang, Junyi Ma, Xuelun Zou, TianXing Yao, Si Li, Junyou Chen, Huifang Zhou, Lianxu Wu, Yanhong Zhou, Le Zhang

Get full text

Surgical Management of the Axilla in Clinically Node-Positive Breast Cancer Patients Converting to Clinical Node Negativity through Neoadjuvant Chemotherapy: Current Status, Knowle... by Maggie Banys-Paluchowski, Maria Luisa Gasparri, Jana de Boniface, Oreste Gentilini, Elmar Stickeler, Steffi Hartmann, Marc Thill, Isabel T. Rubio, Rosa Di Micco, Eduard-Alexandru Bonci, Laura Niinikoski, Michalis Kontos, Guldeniz Karadeniz Cakmak, Michael Hauptmann, Florentia Peintinger, David Pinto, Zoltan Matrai, Dawid Murawa, Geeta Kadayaprath, Lukas Dostalek, Helidon Nina, Petr Krivorotko, Jean-Marc Classe, Ellen Schlichting, Matilda Appelgren, Peter Paluchowski, Christine Solbach, Jens-Uwe Blohmer, Thorsten Kühn, the AXSANA Study Group

“…These results provide the rationale for the multinational prospective cohort study AXSANA initiated by EUBREAST, which started enrollment in June 2020 and aims at recruiting 3000 patients in 20 countries (NCT04373655; Funded by AGO-B, Claudia von Schilling Foundation for Breast Cancer Research, AWOgyn, EndoMag, Mammotome, and MeritMedical).…”
Get full text

What if: A retrospective reconstruction of resection cavity stereotactic radiosurgery to mimic neoadjuvant stereotactic radiosurgery by Gueliz Acker, Gueliz Acker, Gueliz Acker, Marcel Nachbar, Nina Soffried, Bohdan Bodnar, Anastasia Janas, Kiril Krantchev, Goda Kalinauskaite, Anne Kluge, David Shultz, Alfredo Conti, David Kaul, David Kaul, Daniel Zips, Peter Vajkoczy, Carolin Senger

Get full text

HIV DNA persists in hepatocytes in people with HIV-hepatitis B co-infection on antiretroviral therapyResearch in context by Jennifer M. Zerbato, Anchalee Avihingsanon, Kasha P. Singh, Wei Zhao, Claire Deleage, Elias Rosen, Mackenzie L. Cottrell, Ajantha Rhodes, Ashanti Dantanarayana, Carolin Tumpach, Surekha Tennakoon, Megan Crane, David J. Price, Sabine Braat, Hugh Mason, Michael Roche, Angela D.M. Kashuba, Peter A. Revill, Jennifer Audsley, Sharon R. Lewin

Get full text

Healthcare in England was affected by the COVID-19 pandemic across the pancreatic cancer pathway: A cohort study using OpenSAFELY-TPP by Agnieszka Lemanska, Colm Andrews, Louis Fisher, Seb Bacon, Adam E Frampton, Amir Mehrkar, Peter Inglesby, Simon Davy, Keith Roberts, Praveetha Patalay, Ben Goldacre, Brian MacKenna, The OpenSAFELY Collaborative, Alex J Walker

Get full text

A modifiable universal cotinine-chimeric antigen system of NK cells with multiple targets by Hee Young Kang, Soo Yun Lee, Hyun Min Kim, Su Ui Lee, Hyunseung Lee, Mi Young Cho, Se-Chan Oh, Se-Chan Oh, Seok-Min Kim, Seok-Min Kim, Hye Sun Park, Eun Hee Han, Seong-Eun Kim, Hyori Kim, Suk Ran Yoon, Suk Ran Yoon, Junsang Doh, Junho Chung, Kwan Soo Hong, Kwan Soo Hong, Inpyo Choi, Inpyo Choi, Tae-Don Kim, Tae-Don Kim, Tae-Don Kim, Tae-Don Kim

Get full text

Incorporation of Low Concentrations of Gold Nanoparticles: Complex Effects on Radiation Response and Fate of Cancer Cells by Lucie Dobešová, Theresa Gier, Olga Kopečná, Eva Pagáčová, Tomáš Vičar, Felix Bestvater, Jiří Toufar, Alena Bačíková, Pavel Kopel, Radek Fedr, Georg Hildenbrand, Iva Falková, Martin Falk, Michael Hausmann

Get full text

A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53 by Liz Hernandez Borrero, David T Dicker, John Santiago, Jennifer Sanders, Xiaobing Tian, Nagib Ahsan, Avital Lev, Lanlan Zhou, Wafik S El-Deiry

Get full text

Magnetic Resonance Imaging for Monitoring of Hepatic Disease Induced by Ebola Virus: a Nonhuman Primate Proof-of-Concept Study by Ji Hyun Lee, Claudia Calcagno, Irwin M. Feuerstein, Jeffrey Solomon, Venkatesh Mani, Louis Huzella, Marcelo A. Castro, Joseph Laux, Rebecca J. Reeder, Dong-Yun Kim, Gabriella Worwa, David Thomasson, Katie R. Hagen, Danny R. Ragland, Jens H. Kuhn, Reed F. Johnson

Get full text

Framework for Adoption of Next-Generation Sequencing (NGS) Globally in the Oncology Area by Denis Horgan, Yosr Hamdi, Jonathan A. Lal, Teresia Nyawira, Salomé Meyer, Dominique Kondji, Ngiambudulu M. Francisco, Roselle De Guzman, Anupriya Paul, Branka Bernard, Krishna Reddy Nallamalla, Woong-Yang Park, Vijay Triapthi, Ravikant Tripathi, Amber Johns, Mohan P. Singh, Maude E. Phipps, France Dube, Hadi Mohamad Abu Rasheed, Marta Kozaric, Joseph A. Pinto, Stephen Doral Stefani, Maria Eugenia Aponte Rueda, Ricardo Fujita Alarcon, Hugo A. Barrera-Saldana

Get full text

Comprehensive Humoral and Cellular Immune Responses to SARS-CoV-2 Variants in Diverse Chinese Population by Jiwei Li, Jing Wu, Qiuyue Long, Yan’an Wu, Xiaoyi Hu, Yukun He, Mingzheng Jiang, Jia Li, Lili Zhao, Shuoqi Yang, Xiaoyong Chen, Minghui Wang, Jianshi Zheng, Fangfang Wu, Ruiliang Wu, Lihong Ren, Liang Bu, Houzhao Wang, Ke Li, Lijuan Fu, Guojun Zhang, Yali Zheng, Zhancheng Gao

Get full text

Delphi Consensus Among International Experts on the Diagnosis, Management, and Surveillance for Lentigo Maligna by Caterina Longo, Cristian Navarrete-Dechent, Philipp Tschandl, Zoe Apalla, Giuseppe Argenziano, Ralph P. Braun, Veronique Bataille, Horacio Cabo, Rainer Hoffmann-Wellhenhof, Ana Maria Forsea, Claus Garbe, Pascale Guitera, Karls Raimond, Ashfaq A. Marghoob, Josep Malvehy, Veronique del Marmol, David Moreno, Kishwer S. Nehal, Eduardo Nagore, John Paoli, Giovanni Pellacani, Ketty Peris, Susana Puig, H. Peter Soyer, Susan Swetter, Alexander Stratigos, Wilhelm Stolz, Luc Thomas, Danica Tiodorovic, Iris Zalaudek, Harald Kittler, Aimilios Lallas

Get full text

A real-world retrospective, observational study of first-line pembrolizumab plus chemotherapy for metastatic non-squamous non-small cell lung cancer with PD-L1 tumor proportion sco... by Alessandro Cafaro, Flavia Foca, Oriana Nanni, Marco Chiumente, Marina Coppola, Paolo Baldo, Sabrina Orzetti, Fiorenza Enrico, Vito Ladisa, Rosa Lerose, Patrizia Nardulli, Piera Maiolino, Federica Gradellini, Anna Rita Gasbarro, Gisella Carrucciu, Riccardo Provasi, Paola Cristina Cappelletto, Alessandra Pasqualini, Stefano Vecchia, Marianna Veraldi, Adele Emanuela De Francesco, Lucio Crinò, Angelo Delmonte, Carla Masini

Get full text

Evaluation of pre-diagnostic blood protein measurements for predicting survival after lung cancer diagnosisResearch in context by Xiaoshuang Feng, David C. Muller, Hana Zahed, Karine Alcala, Florence Guida, Karl Smith-Byrne, Jian-Min Yuan, Woon-Puay Koh, Renwei Wang, Roger L. Milne, Julie K. Bassett, Arnulf Langhammer, Kristian Hveem, Victoria L. Stevens, Ying Wang, Mikael Johansson, Anne Tjønneland, Rosario Tumino, Mahdi Sheikh, Mattias Johansson, Hilary A. Robbins

“…Authors and data collection supported by the US National Cancer Institute (U19CA203654), INCA (France, 2019-1-TABAC-01), Cancer Research Foundation of Northern Sweden (AMP19-962), and Swedish Department of Health Ministry.…”
Get full text

Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development by Ryan J Geusz, Allen Wang, Joshua Chiou, Joseph J Lancman, Nichole Wetton, Samy Kefalopoulou, Jinzhao Wang, Yunjiang Qiu, Jian Yan, Anthony Aylward, Bing Ren, P Duc Si Dong, Kyle J Gaulton, Maike Sander

Get full text

Interobserver Agreement of PD-L1/SP142 Immunohistochemistry and Tumor-Infiltrating Lymphocytes (TILs) in Distant Metastases of Triple-Negative Breast Cancer: A Proof-of-Concept Stu... by Mieke R. Van Bockstal, Maxine Cooks, Iris Nederlof, Mariël Brinkhuis, Annemiek Dutman, Monique Koopmans, Loes Kooreman, Bert van der Vegt, Leon Verhoog, Celine Vreuls, Pieter Westenend, Marleen Kok, Paul J. van Diest, Inne Nauwelaers, Nele Laudus, Carsten Denkert, David Rimm, Kalliopi P. Siziopikou, Scott Ely, Dimitrios Zardavas, Mustimbo Roberts, Giuseppe Floris, Johan Hartman, Balazs Acs, Dieter Peeters, John M.S. Bartlett, Els Dequeker, Roberto Salgado, Fabiola Giudici, Stefan Michiels, Hugo Horlings, Carolien H. M. van Deurzen

Get full text

DNA dioxygenases TET2 deficiency promotes cigarette smoke induced chronic obstructive pulmonary disease by inducing ferroptosis of lung epithelial cell by Zihang Zeng, Tiao Li, Xiangming Liu, Yiming Ma, Lijuan Luo, ZuLi Wang, Zhiqi Zhao, Herui Li, Xue He, Huihui Zeng, Yongguang Tao, Yan Chen

Get full text

First-in-human phase Ib trial of M9241 (NHS-IL12) plus avelumab in patients with advanced solid tumors, including dose expansion in patients with advanced urothelial carcinoma by Renee N Donahue, Jeffrey Schlom, James L Gulley, Mario Sznol, Andreas Schroeder, Julius Strauss, Luc Dirix, Michele Maio, Frank Beier, Alain Ravaud, Jean-Laurent Deville, Marco Maruzzo, XiaoZhe Wang, Yulia Vugmeyster, Sarah Chennoufi, Yo-Ting Tsai, Russell K Pachynski, Theodore S Gourdin, Joerg Seebeck

Get full text

Network-based identification and prioritization of key transcriptional factors of diabetic kidney disease by Ikhlak Ahmed, Mubarak Ziab, Sahar Da’as, Waseem Hasan, Sujitha P. Jeya, Elbay Aliyev, Sabah Nisar, Ajaz A. Bhat, Khalid Adnan Fakhro, Ammira S. Alshabeeb Akil

Get full text