The Association between Peptic Ulcer Disease and Gastric Cancer: Results from the Stomach Cancer Pooling (StoP) Project Consortium by Pedram Paragomi, Bashir Dabo, Claudio Pelucchi, Rossella Bonzi, Abdulaziz T. Bako, Nabila Muhammad Sanusi, Quan H. Nguyen, Zuo-Feng Zhang, Domenico Palli, Monica Ferraroni, Khanh Truong Vu, Guo-Pei Yu, Federica Turati, David Zaridze, Dmitry Maximovitch, Jinfu Hu, Lina Mu, Stefania Boccia, Roberta Pastorino, Shoichiro Tsugane, Akihisa Hidaka, Robert C. Kurtz, Areti Lagiou, Pagona Lagiou, M. Constanza Camargo, Maria Paula Curado, Nuno Lunet, Jesus Vioque, Paolo Boffetta, Eva Negri, Carlo La Vecchia, Hung N. Luu

Get full text

Identification of CT Values That Could Be Predictive of Necrosis (N-CTav) in Hepatocellular Carcinoma after Lenvatinib Treatment by Makoto Chuma, Hideki Yokoo, Atsushi Hiraoka, Kazuhiko Ueda, Takahiro Yokoyama, Kunihiko Tsuji, Noritomo Shimada, Haruki Uojima, Satoshi Kobayashi, Nobuhiro Hattori, Tomomi Okubo, Masanori Atsukawa, Toru Ishikawa, Koichi Takaguchi, Akemi Tsutsui, Hidenori Toyoda, Toshifumi Tada, Yoshinori Saito, Shunji Hirose, Takaaki Tanaka, Kazuhisa Takeda, Masako Otani, Zenjiro Sekikawa, Tsunamasa Watanabe, Hisashi Hidaka, Manabu Morimoto, Kazushi Numata, Tatehiro Kagawa, Michiie Sakamoto, Takashi Kumada, Shin Maeda

Get full text

Imaging and Molecular Annotation of Xenographs and Tumours (IMAXT): High throughput data and analysis infrastructure by Eduardo A. González-Solares, Ali Dariush, Carlos González-Fernández, Aybüke Küpcü Yoldaş, Alireza Molaeinezhad, Mohammad Al Sa’d, Leigh Smith, Tristan Whitmarsh, Neil Millar, Nicholas Chornay, Ilaria Falciatori, Atefeh Fatemi, Daniel Goodwin, Laura Kuett, Claire M. Mulvey, Marta Páez Ribes, Fatime Qosaj, Andrew Roth, Ignacio Vázquez-García, Spencer S. Watson, Jonas Windhager, Samuel Aparicio, Bernd Bodenmiller, Ed Boyden, Carlos Caldas, Owen Harris, Sohrab P. Shah, Simon Tavaré, CRUK IMAXT Grand Challenge Team, Dario Bressan, Gregory J. Hannon, Nicholas A. Walton

Get full text

Association between severe anaemia and inflammation, risk of IRIS and death in persons with HIV: A multinational cohort studyResearch in context by Mariana Ara..jo-Pereira, Virginia Sheikh, Irini Sereti, Beatriz Barreto-Duarte, Mar.ía B. Arriaga, Rafael Tib..rcio, Caian L. Vinhaes, Manuella Pinto-de-Almeida, Jing Wang, Adam Rupert, Gregg Roby, Douglas Shaffer, Jintanat Ananworanich, Nittaya Phanuphak, Fred Sawe, Bruno B. Andrade

Get full text

Building CapaCITY/É for sustainable transportation: protocol for an implementation science research program in healthy cities by Brent E Hagel, Alison Macpherson, Ben Beck, Ian Pike, Linda Rothman, Darshini Ayton, Marie-Soleil Cloutier, Kevin Manaugh, Meridith Sones, Daniel Fuller, Yan Kestens, Meghan Winters, Audrey R Giles, Helen Skouteris, Patrick Harris, Andrew Howard, M Anne Harris, Brice Batomen, Nazeem Muhajarine, Jennifer R Tomasone, Sarah Moore, Martine Shareck, David Whitehurst, Sara Kirk, Karen Laberee, Zoé Poirier Stephens, Scott Bell, Patricia Collins, Ehab Diab, Mike S Harris, Ugo Lachapelle, Raktim Mitra, Tiffany Muller Myrdahl, Christopher J Pettit, David Wachsmuth

Get full text

Looking Back: International Practice Patterns in Breast Radiation Oncology From a Case-Based Survey Across 54 Countries During the First Surge of the COVID-19 Pandemic by Oluwadamilola T. Oladeru, Samantha A. Dunn, Jian Li, Charlotte E. Coles, Chikako Yamauchi, Jee Suk Chang, Skye Hung-Chun Cheng, Orit Kaidar-Person, Icro Meattini, Duvern Ramiah, Anna Kirby, Tarek Hijal, Gustavo Nader Marta, Philip Poortmans, Josep Isern-Verdum, Yvonne Zissiadis, Birgitte Vrou Offersen, Tamer Refaat, Khaled Elsayad, Hussam Hijazi, Natalia Dengina, Yazid Belkacemi, Feng Deng Luo, Shun Lu, Colleen Griffin, Maya Collins, Phoebe Ryan, Dalia Larios, Laura E. Warren, Rinaa S. Punglia, Julia S. Wong, Daphna Y. Spiegel, Reshma Jagsi, Alphonse Taghian, Jennifer R. Bellon, Alice Y. Ho

Get full text

A Machine-Learning Approach to Developing a Predictive Signature Based on Transcriptome Profiling of Ground-Glass Opacities for Accurate Classification and Exploring the Immune Mic... by Zhenyu Zhao, Zhenyu Zhao, Wei Yin, Wei Yin, Xiong Peng, Xiong Peng, Qidong Cai, Qidong Cai, Boxue He, Boxue He, Shuai Shi, Shuai Shi, Weilin Peng, Weilin Peng, Guangxu Tu, Guangxu Tu, Yunping Li, Dateng Li, Yongguang Tao, Yongguang Tao, Yongguang Tao, Yongguang Tao, Muyun Peng, Muyun Peng, Xiang Wang, Xiang Wang, Fenglei Yu, Fenglei Yu

Get full text

A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation by Marta Castroviejo‐Bermejo, Cristina Cruz, Alba Llop‐Guevara, Sara Gutiérrez‐Enríquez, Mandy Ducy, Yasir Hussein Ibrahim, Albert Gris‐Oliver, Benedetta Pellegrino, Alejandra Bruna, Marta Guzmán, Olga Rodríguez, Judit Grueso, Sandra Bonache, Alejandro Moles‐Fernández, Guillermo Villacampa, Cristina Viaplana, Patricia Gómez, Maria Vidal, Vicente Peg, Xavier Serres‐Créixams, Graham Dellaire, Jacques Simard, Paolo Nuciforo, Isabel T Rubio, Rodrigo Dienstmann, J Carl Barrett, Carlos Caldas, José Baselga, Cristina Saura, Javier Cortés, Olivier Déas, Jos Jonkers, Jean‐Yves Masson, Stefano Cairo, Jean‐Gabriel Judde, Mark J O'Connor, Orland Díez, Judith Balmaña, Violeta Serra

Get full text

Stereotactic ablative body radiotherapy (SABR) combined with immunotherapy (L19-IL2) versus standard of care in stage IV NSCLC patients, ImmunoSABR: a multicentre, randomised contr... by Relinde I. Y. Lieverse, Evert J. Van Limbergen, Cary J. G. Oberije, Esther G. C. Troost, Sine R. Hadrup, Anne-Marie C. Dingemans, Lizza E. L. Hendriks, Franziska Eckert, Crispin Hiley, Christophe Dooms, Yolande Lievens, Monique C. de Jong, Johan Bussink, Xavier Geets, Vincenzo Valentini, Giuliano Elia, Dario Neri, Charlotte Billiet, Amir Abdollahi, David Pasquier, Pierre Boisselier, Ala Yaromina, Dirk De Ruysscher, Ludwig J. Dubois, Philippe Lambin

Get full text

Head and neck cancers survival in Europe, Taiwan, and Japan: results from RARECAREnet Asia based on a privacy-preserving federated infrastructure by Laura Botta, Tomohiro Matsuda, Hadrien Charvat, Hadrien Charvat, Chun-ju Chiang, Wen-Chung Lee, Anna Jacoba van Gestel, Frank Martin, Gijs Geleijnse, Matteo Cellamare, Simone Bonfarnuzzo, Rafael Marcos-Gragera, Rafael Marcos-Gragera, Rafael Marcos-Gragera, Marcela Guevara, Marcela Guevara, Marcela Guevara, Mohsen Mousavi, Stephanie Craig, Jessica Rodrigues, Jordi Rubió-Casadevall, Jordi Rubió-Casadevall, Lisa Licitra, Lisa Licitra, Stefano Cavalieri, Stefano Cavalieri, Carlo Resteghini, Gemma Gatta, Annalisa Trama, the RARECAREnet working group

Get full text

Aerobic exercise increases brain vessel lumen size and blood flow in young adults with elevated blood pressure. Secondary analysis of the TEPHRA randomized clinical trial by Winok Lapidaire, Nils D. Forkert, Wilby Williamson, Odaro Huckstep, Cheryl MJ Tan, Maryam Alsharqi, Afifah Mohamed, Jamie Kitt, Holger Burchert, Pauline Mouches, Helen Dawes, Charlie Foster, Thomas W. Okell, Adam J. Lewandowski, Paul Leeson

Get full text

Helpful Criteria When Implementing NGS Panels in Childhood Lymphoblastic Leukemia by Nerea Vega-Garcia, Rocío Benito, Elena Esperanza-Cebollada, Marta Llop, Cristina Robledo, Clara Vicente-Garcés, Javier Alonso, Eva Barragán, Guerau Fernández, Jesús M. Hernández-Sánchez, Marta Martín-Izquierdo, Joan Maynou, Alfredo Minguela, Adrián Montaño, Margarita Ortega, Montserrat Torrebadell, José Cervera, Joaquín Sánchez, Antonio Jiménez-Velasco, Susana Riesco, Jesús M. Hernández-Rivas, Álvaro Lassaletta, José María Fernández, Susana Rives, José Luis Dapena, Manuel Ramírez, Mireia Camós, on behalf of the Group of Leukemia of the Spanish Society of Pediatric Hematology and Oncology (SEHOP)

“…We used the same samples to assess other commercial panels (Oncomine^TM Childhood Cancer Research Assay; Archer^®FusionPlex^® ALL, and Human Comprehensive Cancer Panel GeneRead Panel v2^®). …”
Get full text

IGF-1R/mTOR Targeted Therapy for Ewing Sarcoma: A Meta-Analysis of Five IGF-1R-Related Trials Matched to Proteomic and Radiologic Predictive Biomarkers by Hesham M. Amin, Ajaykumar C. Morani, Najat C. Daw, Salah-Eddine Lamhamedi-Cherradi, Vivek Subbiah, Brian A. Menegaz, Deeksha Vishwamitra, Ghazaleh Eskandari, Bhawana George, Robert S. Benjamin, Shreyaskumar Patel, Juhee Song, Alexander J. Lazar, Wei-Lien Wang, Razelle Kurzrock, Alberto Pappo, Peter M. Anderson, Gary K. Schwartz, Dejka Araujo, Branko Cuglievan, Ravin Ratan, David McCall, Sana Mohiuddin, John A. Livingston, Eric R. Molina, Aung Naing, Joseph A. Ludwig

Get full text

Longitudinal trajectory of quality of life for patients with melanoma brain metastases: A secondary analysis from a whole brain radiotherapy randomized clinical trial by Iris Bartula, Anh D. Tran, Anna K. Nowak, Tasnia Ahmed, Rachael L. Morton, Bryan H. Burmeister, Kari Dolven-Jacobsen, Jenny Nobes, John F. Thompson, Gerald B. Fogarty, Serigne N Lo, Angela M. Hong

“…Conclusions: Poorer QoL outcomes in the first 12 months after diagnosis of melanoma brain metastases were observed in patients aged ≥ 65 years, females, having 2–3 brain metastases, non-surgical treatment of metastases or adjuvant WBRT.Clinical Trial Registration Number:Whole Brain Radiotherapy Trial (WBRTMel) was registered with the Australian Clinical Trials Registry (ACTRN12607000512426) and ClinicalTrials.gov (NCT01503827).Study Support:This project was funded by Cancer Australia PdCCRS (Grants No. 512358, 1009485, and 1084046) and the National Helath and Medical Research Coucil of Australia (NHMRC; Grant No. 1135285).ADT was supported by a Cancer Australia Priority-driven Collaborative Cancer Research Scheme. Project #1046923. RLM was supported by an NHMRC Fellowship #1194703 and a University of Sydney, Robinson Fellowship. …”
Get full text

Dysregulation of the PRUNE2/PCA3 genetic axis in human prostate cancer: from experimental discovery to validation in two independent patient cohorts by Richard C Lauer, Marc Barry, Tracey L Smith, Andrew Maltez Thomas, Jin Wu, Ruofei Du, Ji-Hyun Lee, Arpit Rao, Andrey S Dobroff, Marco A Arap, Diana N Nunes, Israel T Silva, Emmanuel Dias-Neto, Isan Chen, Dennis J McCance, Webster K Cavenee, Renata Pasqualini, Wadih Arap

Get full text

Adjuvant chemotherapy compared with observation in patients with T2aN0 stage IB lung adenocarcinoma by Po-Hsin Lee, Po-Hsin Lee, Po-Hsin Lee, Po-Hsin Lee, Chun-Ju Chiang, Chun-Ju Chiang, Jeng-Sen Tseng, Jeng-Sen Tseng, Jeng-Sen Tseng, Jeng-Sen Tseng, Zhe-Rong Zheng, Zhe-Rong Zheng, Zhe-Rong Zheng, Kun-Chieh Chen, Kun-Chieh Chen, Cheng-Hsiang Chu, Cheng-Hsiang Chu, Yen-Hsiang Huang, Yen-Hsiang Huang, Yen-Hsiang Huang, Kuo-Hsuan Hsu, Wen-Chung Lee, Wen-Chung Lee, Tsung-Ying Yang, Tsung-Ying Yang, Tsang-Wu Liu, Jiun-Yi Hsia, Jiun-Yi Hsia, Gee-Chen Chang, Gee-Chen Chang, Gee-Chen Chang, Gee-Chen Chang

Get full text

Disparities in stage at diagnosis for liver cancer in China by Tianhao Shan, Xianhui Ran, Huizhang Li, Guoshuang Feng, Siwei Zhang, Xuehong Zhang, Lei Zhang, Lingeng Lu, Lan An, Ruiying Fu, Kexin Sun, Shaoming Wang, Ru Chen, Li Li, Wanqing Chen, Wenqiang Wei, Hongmei Zeng, Jie He

Get full text

High rate of mutations in the BRCA1, BRCA2, CHEK2, NBN, and BLM genes in Russian ovarian cancer patients by Ye. I. Bateneva, M. G. Filippova, A. S. Tyulyandina, A. A. Meshcheryakov, K. I. Zhordania, A. N. Gritsai, V. V. Kadochnikova, D. D. Abramov, A. A. Ragimov, D. Yu. Trofimov, L. N. Lyubchenko

“…Whole peripheral blood samples were collected at the Clinical Subdivisions of the N.N. Blokhin Russian Cancer Research Center and at the Department of Transfusiology of the Acad. …”
Get full text

LOREALAUS: LOrlatinib REAL-World AUStralian Experience in Advanced ALK-Rearranged NSCLC by Marliese Alexander, B.Pharm(Hons), MPH, PhD, Joe Wei, MD, Sagun Parakh, MD, Thomas John, MD, Steven Kao, MD, Adnan Nagrial, MD, Samantha Bowyer, MD, Lydia Warburton, MD, Melissa Moore, MD, Brett G.M. Hughes, MD, Timothy D. Clay, MD, Nick Pavlakis, MD, Benjamin J. Solomon, MD, Malinda Itchins, MD

Get full text

Peroxidasin Deficiency Re-programs Macrophages Toward Pro-fibrolysis Function and Promotes Collagen Resolution in LiverSummary by Mozhdeh Sojoodi, Derek J. Erstad, Stephen C. Barrett, Shadi Salloum, Shijia Zhu, Tongqi Qian, Selene Colon, Eric M. Gale, Veronica Clavijo Jordan, Yongtao Wang, Shen Li, Bahar Ataeinia, Sasan Jalilifiroozinezhad, Michael Lanuti, Lawrence Zukerberg, Peter Caravan, Yujin Hoshida, Raymond T. Chung, Gautam Bhave, Georg M. Lauer, Bryan C. Fuchs, Kenneth K. Tanabe

Get full text