Preanalytical Pitfalls in Untargeted Plasma Nuclear Magnetic Resonance Metabolomics of Endocrine Hypertension by Nikolaos G. Bliziotis, Leo A. J. Kluijtmans, Gerjen H. Tinnevelt, Parminder Reel, Smarti Reel, Katharina Langton, Mercedes Robledo, Christina Pamporaki, Alessio Pecori, Josie Van Kralingen, Martina Tetti, Udo F. H. Engelke, Zoran Erlic, Jasper Engel, Timo Deutschbein, Svenja Nölting, Aleksander Prejbisz, Susan Richter, Jerzy Adamski, Andrzej Januszewicz, Filippo Ceccato, Carla Scaroni, Michael C. Dennedy, Tracy A. Williams, Livia Lenzini, Anne-Paule Gimenez-Roqueplo, Eleanor Davies, Martin Fassnacht, Hanna Remde, Graeme Eisenhofer, Felix Beuschlein, Matthias Kroiss, Emily Jefferson, Maria-Christina Zennaro, Ron A. Wevers, Jeroen J. Jansen, Jaap Deinum, Henri J. L. M. Timmers

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Eicosapentaenoic acid and/or aspirin for preventing colorectal adenomas during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme: the seAFOod RCT by Mark A Hull, Kirsty Sprange, Trish Hepburn, Wei Tan, Aisha Shafayat, Colin J Rees, Gayle Clifford, Richard F Logan, Paul M Loadman, Elizabeth A Williams, Diane Whitham, Alan A Montgomery

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Feasibility of monitoring Global Breast Cancer Initiative Framework key performance indicators in 21 Asian National Cancer Centers Alliance member countriesResearch in context by Sok King Ong, Rei Haruyama, Cheng Har Yip, Tran Thu Ngan, Jingmei Li, Daphne Lai, Yawei Zhang, Siyan Yi, Abhishek Shankar, Evlina Suzanna, So-Youn Jung, Peh Joo Ho, Aasim Yusuf, Ashrafun Nessa, Kyu-Won Jung, Eshani Fernando, Shweta Baral, Maryam Bagherian, Prabhat Pradhan, Uranbolor Jugder, Champadeng Vongdala, Siti Norbayah Yusof, Khin Thiri, Patumrat Sripan, Clarito Cairo, Tomohiro Matsuda, Suleeporn Sangrajran, Veronique Kiak-Mien Tan, Ravi Mehrotra, Benjamin O. Anderson

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Planning preclinical confirmatory multicenter trials to strengthen translation from basic to clinical research – a multi-stakeholder workshop report by Natascha Ingrid Drude, Lorena Martinez-Gamboa, Meggie Danziger, Anja Collazo, Silke Kniffert, Janine Wiebach, Gustav Nilsonne, Frank Konietschke, Sophie K. Piper, Samuel Pawel, Charlotte Micheloud, Leonhard Held, Florian Frommlet, Daniel Segelcke, Esther M. Pogatzki-Zahn, Bernhard Voelkl, Tim Friede, Edgar Brunner, Astrid Dempfle, Bernhard Haller, Marie Juliane Jung, Lars Björn Riecken, Hans-Georg Kuhn, Matthias Tenbusch, Lina Maria Serna Higuita, Edmond J. Remarque, Servan Luciano Grüninger-Egli, Katrin Manske, Sebastian Kobold, Marion Rivalan, Lisa Wedekind, Juliane C. Wilcke, Anne-Laure Boulesteix, Marcus W. Meinhardt, Rainer Spanagel, Simone Hettmer, Irene von Lüttichau, Carla Regina, Ulrich Dirnagl, Ulf Toelch

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Early protective effect of a (“pan”) coronavirus vaccine (PanCoVac) in Roborovski dwarf hamsters after single-low dose intranasal administration by Mohammed O. Abdelaziz, Mohammed O. Abdelaziz, Martin J. Raftery, Martin J. Raftery, Martin J. Raftery, Julian Weihs, Julian Weihs, Olivia Bielawski, Richard Edel, Julia Köppke, Daria Vladimirova, Julia M. Adler, Theresa Firsching, Anne Voß, Achim D. Gruber, Luca V. Hummel, Ivan Fernandez Munoz, Francesca Müller-Marquardt, Gerald Willimsky, Gerald Willimsky, Gerald Willimsky, Nooran S. Elleboudy, Nooran S. Elleboudy, Jakob Trimpert, Günther Schönrich

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A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases by Alexander M. Bernhardt, Steffen Tiedt, Daniel Teupser, Martin Dichgans, Bernhard Meyer, Jens Gempt, Peer-Hendrik Kuhn, Mikael Simons, Carla Palleis, Endy Weidinger, Georg Nübling, Lesca Holdt, Lisa Hönikl, Christiane Gasperi, Pieter Giesbertz, Stephan A. Müller, Stephan Breimann, Stefan F. Lichtenthaler, Bernhard Kuster, Matthias Mann, Axel Imhof, Teresa Barth, Stefanie M. Hauck, Henrik Zetterberg, Markus Otto, Wilko Weichert, Bernhard Hemmer, Johannes Levin

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Evaluation of Antigen-Conjugated Fluorescent Beads to Identify Antigen-Specific B Cells by Isabel Correa, Isabel Correa, Kristina M. Ilieva, Kristina M. Ilieva, Kristina M. Ilieva, Silvia Crescioli, Silvia Crescioli, Sara Lombardi, Mariangela Figini, Anthony Cheung, Anthony Cheung, James F. Spicer, Andrew N. J. Tutt, Andrew N. J. Tutt, Frank O. Nestle, Frank O. Nestle, Frank O. Nestle, Panagiotis Karagiannis, Panagiotis Karagiannis, Panagiotis Karagiannis, Katie E. Lacy, Sophia N. Karagiannis, Sophia N. Karagiannis, Sophia N. Karagiannis

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Faecal immunochemical tests versus colonoscopy for post-polypectomy surveillance: an accuracy, acceptability and economic study by Wendy Atkin, Amanda J Cross, Ines Kralj-Hans, Eilidh MacRae, Carolyn Piggott, Sheena Pearson, Kate Wooldrage, Jeremy Brown, Fiona Lucas, Aaron Prendergast, Natalie Marchevsky, Bhavita Patel, Kevin Pack, Rosemary Howe, Hanna Skrobanski, Robert Kerrison, Nicholas Swart, Julia Snowball, Stephen W Duffy, Stephen Morris, Christian von Wagner, Stephen Halloran

“…Funding: National Institute for Health Research (NIHR) Health Technology Assessment programme, NIHR Imperial Biomedical Research Centre and the Bobby Moore Fund for Cancer Research UK. MAST Group Ltd provided FIT kits.…”
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Molecular subtypes predict the preferential site of distant metastasis in advanced breast cancer: a nationwide retrospective study by Jin-Hu Fan, Su Zhang, Huan Yang, Zong-Bi Yi, Qu-Chang Ouyang, Min Yan, Xiao-Jia Wang, Xi-Chun Hu, Ze-Fei Jiang, Tao Huang, Zhong-Sheng Tong, Shu-Sen Wang, Yong-Mei Yin, Hui Li, Run-Xiang Yang, Hua-Wei Yang, Yue-E. Teng, Tao Sun, Li Cai, Hong-Yuan Li, Xue-Nong Ouyang, Jian-Jun He, Xin-Lan Liu, Shun-E. Yang, Jia-Yu Wang, Bing-He Xu, You-Lin Qiao

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Liver and muscle circadian clocks cooperate to support glucose tolerance in mice by Jacob G. Smith, Kevin B. Koronowski, Thomas Mortimer, Tomoki Sato, Carolina M. Greco, Paul Petrus, Amandine Verlande, Siwei Chen, Muntaha Samad, Ekaterina Deyneka, Lavina Mathur, Ronnie Blazev, Jeffrey Molendijk, Arun Kumar, Oleg Deryagin, Mireia Vaca-Dempere, Valentina Sica, Peng Liu, Valerio Orlando, Benjamin L. Parker, Pierre Baldi, Patrick-Simon Welz, Cholsoon Jang, Selma Masri, Salvador Aznar Benitah, Pura Muñoz-Cánoves, Paolo Sassone-Corsi

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Dynamic altruistic cooperation within breast tumors by Muhammad Sufyan Bin Masroni, Kee Wah Lee, Victor Kwan Min Lee, Siok Bian Ng, Chao Teng Law, Kok Siong Poon, Bernett Teck-Kwong Lee, Zhehao Liu, Yuen Peng Tan, Wee Ling Chng, Steven Tucker, Lynette Su-Mien Ngo, George Wai Cheong Yip, Min En Nga, Susan Swee Shan Hue, Thomas Choudary Putti, Boon Huat Bay, Qingsong Lin, Lihan Zhou, Mikael Hartman, Tze Ping Loh, Manikandan Lakshmanan, Sook Yee Lee, Vinay Tergaonkar, Huiwen Chua, Adeline Voon Hui Lee, Eric Yew Meng Yeo, Mo-Huang Li, Chan Fong Chang, Zizheng Kee, Karen Mei-Ling Tan, Soo Yong Tan, Evelyn Siew-Chuan Koay, Marco Archetti, Sai Mun Leong

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Impact of individual level uncertainty of lung cancer polygenic risk score (PRS) on risk stratification by Xinan Wang, Ziwei Zhang, Yi Ding, Tony Chen, Lorelei Mucci, Demetrios Albanes, Maria Teresa Landi, Neil E. Caporaso, Stephen Lam, Adonina Tardon, Chu Chen, Stig E. Bojesen, Mattias Johansson, Angela Risch, Heike Bickeböller, H-Erich Wichmann, Gadi Rennert, Susanne Arnold, Paul Brennan, James D. McKay, John K. Field, Sanjay S. Shete, Loic Le Marchand, Geoffrey Liu, Angeline S. Andrew, Lambertus A. Kiemeney, Shan Zienolddiny-Narui, Annelie Behndig, Mikael Johansson, Angie Cox, Philip Lazarus, Matthew B. Schabath, Melinda C. Aldrich, Rayjean J. Hung, Christopher I. Amos, Xihong Lin, David C. Christiani

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MUlticenter STudy of tissue plasminogen activator (alteplase) use in COVID‐19 severe respiratory failure (MUST COVID): A retrospective cohort study by Christopher D. Barrett, Hunter B. Moore, Ernest E. Moore, Dudley Benjamin Christie III, Sarah Orfanos, Lorenzo Anez‐Bustillos, Rashi Jhunjhunwala, Sabiha Hussain, Shahzad Shaefi, Janice Wang, Negin Hajizadeh, Elias N. Baedorf‐Kassis, Ammar Al‐Shammaa, Krystal Capers, Valerie Banner‐Goodspeed, Franklin L. Wright, Todd Bull, Peter K. Moore, Hannah Nemec, John Thomas Buchanan, Cory Nonnemacher, Natalie Rajcooar, Ramona Ramdeo, Mena Yacoub, Ana Guevara, Aileen Espinal, Laith Hattar, Andrew Moraco, Robert McIntyre, Daniel S. Talmor, Angela Sauaia, Michael B. Yaffe

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Applying post-neoadjuvant pathologic stage as prognostic tool in esophageal squamous cell carcinoma by Weiming Han, Wei Deng, Qifeng Wang, Wenjie Ni, Chen Li, Zongmei Zhou, Jun Liang, Dongfu Chen, Qinfu Feng, Nan Bi, Tao Zhang, Xin Wang, Lei Deng, Wenqing Wang, Wenyang Liu, Jianyang Wang, Qi Xue, Yousheng Mao, Xiangyang Liu, Dekang Fang, Jian Li, Dali Wang, Jun Zhao, Zefen Xiao

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Age-related differences of cerebellar cortex and nuclei: MRI findings in healthy controls and its application to spinocerebellar ataxia (SCA6) patients by Dominik Jäschke, Katharina M. Steiner, Dae-In Chang, Jens Claaßen, Ellen Uslar, Andreas Thieme, Marcus Gerwig, Viktor Pfaffenrot, Thomas Hulst, Alexander Gussew, Stefan Maderwald, Sophia L. Göricke, Martina Minnerop, Mark E. Ladd, Jürgen R. Reichenbach, Dagmar Timmann, Andreas Deistung

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Characterizing Risk Factors for Hospitalization and Clinical Characteristics in a Cohort of COVID-19 Patients Enrolled in the GENCOV Study by Gregory Morgan, Selina Casalino, Sunakshi Chowdhary, Erika Frangione, Chun Yiu Jordan Fung, Simona Haller, Elisa Lapadula, Mackenzie Scott, Dawit Wolday, Juliet Young, Saranya Arnoldo, Navneet Aujla, Erin Bearss, Alexandra Binnie, Yvonne Bombard, Bjug Borgundvaag, Laurent Briollais, Marc Dagher, Luke Devine, Hanna Faghfoury, Steven M. Friedman, Anne-Claude Gingras, Lee W. Goneau, Zeeshan Khan, Tony Mazzulli, Shelley L. McLeod, Romina Nomigolzar, Abdul Noor, Trevor J. Pugh, David Richardson, Harpreet Kaur Satnam Singh, Jared Simpson, Seth Stern, Lisa Strug, Ahmed Taher, Jordan Lerner-Ellis, Jennifer Taher

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Re:GEN Open: The Impact of Genomics and Biotechnology on the Future of Medicine by Vasu Punj

“…The journal will cover all aspects of basic and translational biomedical research under eight broad sections: Basic Biomedical Research Translational Biomedical Research Drug Development Cancer Research Regenerative Medicine Cell and Gene Therapy Infectious Disease Synthetic and Systems Biology Synthetic biotechnology is reshaping the way humans live, but only a few journals are dedicated to this field. …”
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DNA Mismatch Repair Gene Variant Classification: Evaluating the Utility of Somatic Mutations and Mismatch Repair Deficient Colonic Crypts and Endometrial Glands by Romy Walker, Khalid Mahmood, Julia Como, Mark Clendenning, Jihoon E. Joo, Peter Georgeson, Sharelle Joseland, Susan G. Preston, Bernard J. Pope, James M. Chan, Rachel Austin, Jasmina Bojadzieva, Ainsley Campbell, Emma Edwards, Margaret Gleeson, Annabel Goodwin, Marion T. Harris, Emilia Ip, Judy Kirk, Julia Mansour, Helen Mar Fan, Cassandra Nichols, Nicholas Pachter, Abiramy Ragunathan, Allan Spigelman, Rachel Susman, Michael Christie, Mark A. Jenkins, Rish K. Pai, Christophe Rosty, Finlay A. Macrae, Ingrid M. Winship, Daniel D. Buchanan

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Transdifferentiation of Human Circulating Monocytes Into Neuronal-Like Cells in 20 Days and Without Reprograming by Alfredo Bellon, Alfredo Bellon, Alfredo Bellon, Alfredo Bellon, Alfredo Bellon, Alfredo Bellon, Alfredo Bellon, Amelie Wegener, Amelie Wegener, Amelie Wegener, Amelie Wegener, Adam R. Lescallette, Michael Valente, Michael Valente, Michael Valente, Seung-Kwon Yang, Seung-Kwon Yang, Robert Gardette, Robert Gardette, Julien Matricon, Julien Matricon, Faycal Mouaffak, Faycal Mouaffak, Faycal Mouaffak, Paula Watts, Lene Vimeux, Lene Vimeux, Lene Vimeux, Jong K. Yun, Yuka Imamura Kawasawa, Yuka Imamura Kawasawa, Gary A. Clawson, Elisabeta Blandin, Elisabeta Blandin, Boris Chaumette, Boris Chaumette, Boris Chaumette, Boris Chaumette, Therese M. Jay, Therese M. Jay, Marie-Odile Krebs, Marie-Odile Krebs, Marie-Odile Krebs, Vincent Feuillet, Vincent Feuillet, Vincent Feuillet, Anne Hosmalin, Anne Hosmalin, Anne Hosmalin

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Lack of racial and ethnic diversity in lung cancer cell lines contributes to lung cancer health disparities by Christopher Leon, Christopher Leon, Christopher Leon, Eugene Manley, Aaron M. Neely, Aaron M. Neely, Aaron M. Neely, Jonathan Castillo, Jonathan Castillo, Michele Ramos Correa, Michele Ramos Correa, Diego A. Velarde, Diego A. Velarde, Diego A. Velarde, Minxiao Yang, Minxiao Yang, Pablo E. Puente, Pablo E. Puente, Pablo E. Puente, Diana I. Romero, Bing Ren, Wenxuan Chai, Matthew Gladstone, Matthew Gladstone, Matthew Gladstone, Nazarius S. Lamango, Yong Huang, Ite A. Offringa, Ite A. Offringa, Ite A. Offringa, Ite A. Offringa

“…The lack of an appropriately diverse collection of lung cancer cell lines and lung cancer cell-of-origin lines severely limits racially and ethnically inclusive lung cancer research. It impedes the ability to develop inclusive models, screen comprehensively for effective compounds, pre-clinically test new drugs, and optimize precision medicine. …”
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