The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019 by Tran, Khanh Bao, Lang, Justin J., Compton, Kelly, Xu, Rixing, Acheson, Alistair R., Henrikson, Hannah Jacqueline, Kocarnik, Jonathan M., Penberthy, Louise, Aali, Amirali, Abbas, Qamar, Abbasi, Behzad, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abbastabar, Hedayat, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdelwahab, Ahmed Abdelwahab, Abdoli, Gholamreza, Abdulkadir, Hanan Abdulkadir, Abedi, Aidin, Abegaz, Kedir Hussein, Abidi, Hassan, Aboagye, Richard Gyan, Abolhassani, Hassan, Absalan, Abdorrahim, Abtew, Yonas Derso, Abubaker Ali, Hiwa, Abu-Gharbieh, Eman, Achappa, Basavaprabhu

“…A total of 82 risk–outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. …”
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Immune and behavioral correlates of protection against symptomatic post-vaccination SARS-CoV-2 infection by Emilie Goguet, Emilie Goguet, Cara H. Olsen, William A. Meyer, Sara Ansari, John H. Powers, Tonia L. Conner, Si’Ana A. Coggins, Si’Ana A. Coggins, Wei Wang, Richard Wang, Luca Illinik, Luca Illinik, Margaret Sanchez Edwards, Margaret Sanchez Edwards, Belinda M. Jackson-Thompson, Belinda M. Jackson-Thompson, Monique Hollis-Perry, Gregory Wang, Gregory Wang, Yolanda Alcorta, Yolanda Alcorta, Mimi A. Wong, Mimi A. Wong, David Saunders, Roshila Mohammed, Roshila Mohammed, Bolatito Balogun, Bolatito Balogun, Priscilla Kobi, Priscilla Kobi, Lakeesha Kosh, Lakeesha Kosh, Kimberly Bishop-Lilly, Regina Z. Cer, Catherine E. Arnold, Catherine E. Arnold, Logan J. Voegtly, Logan J. Voegtly, Maren Fitzpatrick, Maren Fitzpatrick, Andrea E. Luquette, Andrea E. Luquette, Francisco Malagon, Francisco Malagon, Orlando Ortega, Orlando Ortega, Edward Parmelee, Edward Parmelee, Julian Davies, Julian Davies, Alyssa R. Lindrose, Alyssa R. Lindrose, Hannah Haines-Hull, Hannah Haines-Hull, Matthew S. Moser, Matthew S. Moser, Emily C. Samuels, Emily C. Samuels, Marana S. Rekedal, Marana S. Rekedal, Elizabeth K. Graydon, Elizabeth K. Graydon, Allison M. W. Malloy, David R. Tribble, Timothy H. Burgess, Wesley Campbell, Sara Robinson, Christopher C. Broder, Robert J. O’Connell, Carol D. Weiss, Simon Pollett, Simon Pollett, Eric D. Laing, Edward Mitre

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An updated examination of the perception of barriers for pharmacogenomics implementation and the usefulness of drug/gene pairs in Latin America and the Caribbean by Aimeé Salas-Hernández, Macarena Galleguillos, Matías Carrasco, Andrés López-Cortés, María Ana Redal, Dora Fonseca-Mendoza, Patricia Esperón, Farith González-Martínez, Ismael Lares-Asseff, Alberto Lazarowski, Verónica Loera-Castañeda, Diadelis Remírez, Matías F. Martínez, Matías F. Martínez, Rodrigo Vargas, Fabricio Rios-Santos, Antonio Macho, Juan P. Cayún, Germán R. Perez, Carolina Gutierrez, Leslie C. Cerpa, Tamara Leiva, Susan Calfunao, Susan Calfunao, Lesly Xajil, Christopher Sandoval, Christopher Sandoval, Marcelo Suárez, Marcelo Suárez, Ariana Gonzalez, Gabriela Echeverría-Garcés, Luis Sullón-Dextre, Eugenia Cordero-García, Alexis R. Morales, Andrea Avendaño, Enrique Sánchez, Laura C. Bastone, Cesar Lara, Patricia Zuluaga-Arias, Ana María Soler, Julio Da Luz, Gabriela Burgueño-Rodríguez, Marcelo Vital, Elizabeth Reyes-Reyes, Alexander Huaccha, Yeimy V. Ariza, Naomi Tzul, Ana L. Rendón, Roberto Serrano, Larissa Acosta, Angelo Motta-Pardo, Leonardo Beltrán-Angarita, Leonardo Beltrán-Angarita, Erika Brand, Miguel A. Jiménez, Gladys Maribel Hidalgo-Lozada, Marina M. J. Romero-Prado, Karla Escobar-Castro, Mariel Umaña-Rivas, Juan D. Vivas, Paola Lagos, Yineth Ballén Martínez, Sharleth Quesada, Camila Calfio, Maria L. Arias, María A. Lavanderos, Dante D. Cáceres, Alberto Salazar-Granara, Nelson M. Varela, Luis A. Quiñones, Luis A. Quiñones

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Systems biology and cancer, [Editorial] by Soto, A, Sonnenschein, C, Maini, P

“…Baker et al. have introduced the concept of “paradigm instability” when referring to current state of affairs through which the field of cancer research is traversing. Thus, they focus on a number of paradoxes that exist in this field and cautiously point at ways that might increase knowledge about the disease and also benefit patients. …”

Tisagenlecleucel utilisation and outcomes across refractory, first relapse and multiply relapsed B-cell acute lymphoblastic leukemia: a retrospective analysis of real-world pattern... by Valentin Barsan, Yimei Li, Snehit Prabhu, Christina Baggott, Khanh Nguyen, Holly Pacenta, Christine L. Phillips, Jenna Rossoff, Heather Stefanski, Julie-An Talano, Amy Moskop, Susanne Baumeister, Michael R. Verneris, Gary Douglas Myers, Nicole A. Karras, Stacy Cooper, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Amy Keating, Vanessa Fabrizio, Vasant Chinnabhandar, Michael Kunicki, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora M. Schultz

“…Baldrick's/Stand Up 2 Cancer, Parker Institute for Cancer Immunotherapy, Virginia and D.K. Ludwig Fund for Cancer Research.…”
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Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 by Daniela Matuozzo, Estelle Talouarn, Astrid Marchal, Peng Zhang, Jeremy Manry, Yoann Seeleuthner, Yu Zhang, Alexandre Bolze, Matthieu Chaldebas, Baptiste Milisavljevic, Adrian Gervais, Paul Bastard, Takaki Asano, Lucy Bizien, Federica Barzaghi, Hassan Abolhassani, Ahmad Abou Tayoun, Alessandro Aiuti, Ilad Alavi Darazam, Luis M. Allende, Rebeca Alonso-Arias, Andrés Augusto Arias, Gokhan Aytekin, Peter Bergman, Simone Bondesan, Yenan T. Bryceson, Ingrid G. Bustos, Oscar Cabrera-Marante, Sheila Carcel, Paola Carrera, Giorgio Casari, Khalil Chaïbi, Roger Colobran, Antonio Condino-Neto, Laura E. Covill, Ottavia M. Delmonte, Loubna El Zein, Carlos Flores, Peter K. Gregersen, Marta Gut, Filomeen Haerynck, Rabih Halwani, Selda Hancerli, Lennart Hammarström, Nevin Hatipoğlu, Adem Karbuz, Sevgi Keles, Christèle Kyheng, Rafael Leon-Lopez, Jose Luis Franco, Davood Mansouri, Javier Martinez-Picado, Ozge Metin Akcan, Isabelle Migeotte, Pierre-Emmanuel Morange, Guillaume Morelle, Andrea Martin-Nalda, Giuseppe Novelli, Antonio Novelli, Tayfun Ozcelik, Figen Palabiyik, Qiang Pan-Hammarström, Rebeca Pérez de Diego, Laura Planas-Serra, Daniel E. Pleguezuelo, Carolina Prando, Aurora Pujol, Luis Felipe Reyes, Jacques G. Rivière, Carlos Rodriguez-Gallego, Julian Rojas, Patrizia Rovere-Querini, Agatha Schlüter, Mohammad Shahrooei, Ali Sobh, Pere Soler-Palacin, Yacine Tandjaoui-Lambiotte, Imran Tipu, Cristina Tresoldi, Jesus Troya, Diederik van de Beek, Mayana Zatz, Pawel Zawadzki, Saleh Zaid Al-Muhsen, Mohammed Faraj Alosaimi, Fahad M. Alsohime, Hagit Baris-Feldman, Manish J. Butte, Stefan N. Constantinescu, Megan A. Cooper, Clifton L. Dalgard, Jacques Fellay, James R. Heath, Yu-Lung Lau, Richard P. Lifton, Tom Maniatis, Trine H. Mogensen, Horst von Bernuth, Alban Lermine, Michel Vidaud, Anne Boland, Jean-François Deleuze, Robert Nussbaum, Amanda Kahn-Kirby, France Mentre, Sarah Tubiana, Guy Gorochov, Florence Tubach, Pierre Hausfater, COVID Human Genetic Effort, COVIDeF Study Group, French COVID Cohort Study Group, CoV-Contact Cohort, COVID Clinicians, Orchestra Working Group, Amsterdam UMC Covid-19 Biobank, NIAID-USUHS COVID Study Group, Isabelle Meyts, Shen-Ying Zhang, Anne Puel, Luigi D. Notarangelo, Stephanie Boisson-Dupuis, Helen C. Su, Bertrand Boisson, Emmanuelle Jouanguy, Jean-Laurent Casanova, Qian Zhang, Laurent Abel, Aurélie Cobat

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Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy by Przulj Dunja, Pesola Francesca, Myers Smith Katie, McRobbie Hayden, Coleman Tim, Lewis Sarah, Griffith Christopher, Walton Robert, Whitemore Rachel, Clark Miranda, Ussher Michael, Sinclair Lesley, Seager Emily, Cooper Sue, Bauld Linda, Naughton Felix, Sasieni Peter, Manyonda Isaac, Hajek Peter

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Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 by Daniela Matuozzo, Estelle Talouarn, Astrid Marchal, Peng Zhang, Jeremy Manry, Yoann Seeleuthner, Yu Zhang, Alexandre Bolze, Matthieu Chaldebas, Baptiste Milisavljevic, Adrian Gervais, Paul Bastard, Takaki Asano, Lucy Bizien, Federica Barzaghi, Hassan Abolhassani, Ahmad Abou Tayoun, Alessandro Aiuti, Ilad Alavi Darazam, Luis M. Allende, Rebeca Alonso-Arias, Andrés Augusto Arias, Gokhan Aytekin, Peter Bergman, Simone Bondesan, Yenan T. Bryceson, Ingrid G. Bustos, Oscar Cabrera-Marante, Sheila Carcel, Paola Carrera, Giorgio Casari, Khalil Chaïbi, Roger Colobran, Antonio Condino-Neto, Laura E. Covill, Ottavia M. Delmonte, Loubna El Zein, Carlos Flores, Peter K. Gregersen, Marta Gut, Filomeen Haerynck, Rabih Halwani, Selda Hancerli, Lennart Hammarström, Nevin Hatipoğlu, Adem Karbuz, Sevgi Keles, Christèle Kyheng, Rafael Leon-Lopez, Jose Luis Franco, Davood Mansouri, Javier Martinez-Picado, Ozge Metin Akcan, Isabelle Migeotte, Pierre-Emmanuel Morange, Guillaume Morelle, Andrea Martin-Nalda, Giuseppe Novelli, Antonio Novelli, Tayfun Ozcelik, Figen Palabiyik, Qiang Pan-Hammarström, Rebeca Pérez de Diego, Laura Planas-Serra, Daniel E. Pleguezuelo, Carolina Prando, Aurora Pujol, Luis Felipe Reyes, Jacques G. Rivière, Carlos Rodriguez-Gallego, Julian Rojas, Patrizia Rovere-Querini, Agatha Schlüter, Mohammad Shahrooei, Ali Sobh, Pere Soler-Palacin, Yacine Tandjaoui-Lambiotte, Imran Tipu, Cristina Tresoldi, Jesus Troya, Diederik van de Beek, Mayana Zatz, Pawel Zawadzki, Saleh Zaid Al-Muhsen, Mohammed Faraj Alosaimi, Fahad M. Alsohime, Hagit Baris-Feldman, Manish J. Butte, Stefan N. Constantinescu, Megan A. Cooper, Clifton L. Dalgard, Jacques Fellay, James R. Heath, Yu-Lung Lau, Richard P. Lifton, Tom Maniatis, Trine H. Mogensen, Horst von Bernuth, Alban Lermine, Michel Vidaud, Anne Boland, Jean-François Deleuze, Robert Nussbaum, Amanda Kahn-Kirby, France Mentre, Sarah Tubiana, Guy Gorochov, Florence Tubach, Pierre Hausfater, COVID Human Genetic Effort, COVIDeF Study Group, French COVID Cohort Study Group, CoV-Contact Cohort, COVID-STORM Clinicians, COVID Clinicians, Orchestra Working Group, Amsterdam UMC Covid-19 Biobank, NIAID-USUHS COVID Study Group, Isabelle Meyts, Shen-Ying Zhang, Anne Puel, Luigi D. Notarangelo, Stephanie Boisson-Dupuis, Helen C. Su, Bertrand Boisson, Emmanuelle Jouanguy, Jean-Laurent Casanova, Qian Zhang, Laurent Abel, Aurélie Cobat

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Biobanks and Informed Consent by Gabriella Foe

“…Broad or categorical consent does not mention specific studies; rather, it allows participants to choose the different fields of studies toward which they would like their samples to contribute (e.g. diabetic research, cancer research). Participants determine their participation by checking boxes beside different categories. …”
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Working hours and cardiovascular disease by Reiner Rugulies

“…Night shift work has been of particular interest for cancer research (30) but might also be relevant with regard to cardiovascular diseases. …”
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Factores de riesgo asociados a metástasis en pacientes con cáncer de próstata by Emily Gabriela Chimbo Acuña, Karen Gabriela Valverde Zambrano, Iván Altamirano

“…Family History of Breast or Prostate Cancer and Prostate Cancer Risk. Clinical Cancer Research. 1 de diciembre de 2018;24(23):5910-7. …”
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A common genetic variation in GZMB may associate with cancer risk in patients with Lynch syndrome by Vince Kornél Grolmusz, Vince Kornél Grolmusz, Vince Kornél Grolmusz, Vince Kornél Grolmusz, Petra Nagy, István Likó, István Likó, Henriett Butz, Henriett Butz, Henriett Butz, Henriett Butz, Henriett Butz, Tímea Pócza, Anikó Bozsik, Anikó Bozsik, Anikó Bozsik, János Papp, János Papp, János Papp, Edit Oláh, Attila Patócs, Attila Patócs, Attila Patócs, Attila Patócs

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Prognostic value of midkine, syndecan-1, hyaluronan synthase-2, sestrin-1, laminin subunit alpha-4 and fibulin-3 for malignant pleural mesothelioma by Hakan Akgun, Selma Metintas, Guntulu Ak, Secil Demirkol Canlı, Murat Isbilen, Ali O. Gure, Muzaffer Metintas

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Current misconception 3: that subgroup-specific trial mortality results often provide a good basis for individualising patient care. by Peto, R

“…We hope that this series will prove instructive to cancer researchers in other disciplines as well as to students of epidemiology. …”

Neural functions in cancer: Data analyses and database construction by Renbo Tan, Renbo Tan, Feilong Wang, Feilong Wang, Yi Zhou, Zhenyu Huang, Zhenyu Huang, Zheng An, Ying Xu, Ying Xu

“…A database, called NGC, is developed for organizing such derived neural functions and associations, along with gene expressions and functional annotations collected from public databases, aiming to provide an integrated and publicly available information resource to enable cancer researchers to take full advantage of the relevant information in their research, facilitated by tools provided by NGC.…”
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RAS Dimers: The Novice Couple at the RAS-ERK Pathway Ball by Ana Herrero, Piero Crespo

“…Thus, the pharmacological disruption of RAS dimers has emerged as an additional target for cancer researchers in the quest for a means to curtail aberrant RAS activity.…”
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Perspectives on common chronic diseases in adult cancer patients in South Africa by Maureen Joffe, Oluwatosin A. Ayeni, Witness Mapanga, Paul Ruff, Nivashini Murugan, Herbert Cubasch, Shane A. Norris

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Molecular characterization of plasmacytoid urothelial carcinoma and the impact on treatment implications by Kristin Weiss, Kathryn H. Gessner, Alysen Demzik, Elizabeth Moreton, William Y. Kim, Sara E. Wobker, Tracy L. Rose, Matthew I. Milowsky, Marc A. Bjurlin

“…Bladder cancer researchers and clinicians have increasingly viewed tumor biology through the lens of genomic and molecular alterations, drastically improving our knowledge of the underlying disease biology. …”
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ACSL3 and ACSL4, Distinct Roles in Ferroptosis and Cancers by Yufei Yang, Ting Zhu, Xu Wang, Fen Xiong, Zhangmin Hu, Xuehan Qiao, Xiao Yuan, Deqiang Wang

“…Here, we present a summary of the current knowledge on ACSL3 and ACSL4 and their functions in various cancers. Research on the molecular mechanisms involved in the regulation of ferroptosis is critical to developing targeted therapies for cancer.…”
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3D Breast Tumor Models for Radiobiology Applications by Akhilandeshwari Ravichandran, Julien Clegg, Mark N. Adams, Madison Hampson, Andrew Fielding, Laura J. Bray

“…However, there has been significant uptake of three-dimensional (3D) in vitro models by cancer researchers over the past decade, highlighting a complimentary model for studies of radiotherapy, especially in conjunction with chemotherapy. …”
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