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12721
The role of microbiomes in gastrointestinal cancers: new insights
Published 2024-02-01“…Additionally, we delve into the intricate mechanisms through which intestinal microbes influence the efficacy of GI cancer treatments.…”
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12722
Molecular Determinant of DIDS Analogs Targeting RAD51 Activity
Published 2021-09-01“…It is shown that overexpression of the RAD51 protein is correlated with increased survival of cancer cells to cancer treatments. For the past decade, RAD51 overexpression-mediated resistance has justified the development of targeted inhibitors. …”
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12723
Smart Nanotherapeutics and Lung Cancer
Published 2021-11-01“…This review highlights the most advanced and novel nanotechnology-based strategies, including targeted nanodrug delivery systems, stimuli-responsive nanoparticles, and bio-nanocarriers, which have recently been employed in preclinical and clinical investigations to overcome the current challenges in lung cancer treatments.…”
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12724
The Role of Genetic Mutations in Mitochondrial-Driven Cancer Growth in Selected Tumors: Breast and Gynecological Malignancies
Published 2023-04-01“…Given that there is always room for improvement in cancer treatments and in cancer patient management, it is important to discover new therapeutic targets for affected individuals. …”
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12725
Optimal CAR T-cell Immunotherapy Strategies for a Leukemia Treatment Model
Published 2020-11-01“…Although so far, this procedure only helps 50–90% of patients and, like other cancer treatments, has serious side effects. In this work, we have proposed a controlled model for leukemia treatment to explore possible ways to improve immunotherapy methodology. …”
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12726
THE EFFECTS OF QUALITY OF LIFE ON RECONSTRUCTIVE SURGERY AND EDUCATION OF THE PATIENTS ON BREAST CANCER
Published 2009-04-01“…The education given about cancer treatments and its side effects make adaptation of patients easier in the following period and decreas psychiatric morbidity. …”
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12727
<i>Limnospira indica</i> PCC8005 and <i>Lacticaseibacillus rhamnosus</i> GG Mixed Dietary Combination Reduces Pelvic Irradiation-Induced Symptoms in Mice
Published 2023-05-01“…Throughout their cancer treatments, around half of all patients will undergo irradiation that is accompanied by several side effects reducing their quality of life and leading to the interruption or extension of their treatment course. …”
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12728
Modulation of the Tumor Stroma and Associated Novel Nanoparticle Strategies to Enhance Tumor Targeting
Published 2024-02-01“…Modulation of the TME may therefore enhance the efficacy of current cancer treatments and facilitate the development of novel treatment methods as an alternative for invasive resection procedures.…”
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12729
Radiotherapy–Immunotherapy Combination: How Will We Bridge the Gap Between Pre-Clinical Promise and Effective Clinical Delivery?
Published 2021-01-01“…Radiotherapy (RT) is highly effective at directly killing tumor cells and plays an important part in cancer treatments being delivered to around 50% of all cancer patients. …”
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12730
Extracellular Vesicles as Drug Targets and Delivery Vehicles for Cancer Therapy
Published 2022-12-01“…Furthermore, we also outline the drawbacks of the existing anti-cancer treatments and the future prospective of EV-based therapeutics.…”
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12731
A Multidisciplinary Approach to Patients with Psoriasis and a History of Malignancies or On-Treatment for Solid Tumors: A Narrative Literature Review
Published 2023-12-01“…Some patients may continue anti-psoriasis therapy during cancer treatments. Enhanced comprehension of the biological mechanisms in cancer progression and the immune microenvironment of psoriasis holds promise for refining therapeutic strategies. …”
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12732
Magnetic Nanoparticles Used in Oncology
Published 2021-10-01“…Recently, magnetic nanoparticles (MNPs) have more and more often been used in experimental studies on cancer treatments, which have become one of the biggest challenges in medical research. …”
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12733
Matrix mechanophysical factor: pore size governs the cell behavior in cancer
Published 2023-12-01“…A comprehensive interpretation of ECM pore size would contribute toward a better understanding of the reciprocal interaction between pore size and tumor progression and can be used as a promising target for cancer treatments. In this review, we abridged the knowledge pertaining to (1) ECM and pore size, (2) the importance of pore size and its interplay with cancer, and (3) current advancement in the field of biomaterials to study pore size. …”
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12734
Biological Aspects of Inflamm-Aging in Childhood Cancer Survivors
Published 2021-09-01“…Anti-cancer treatments improve survival in children with cancer. …”
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12735
Epigallocatechin-3-gallate and cancer: focus on the role of microRNAs
Published 2023-10-01“…In this review, we aim to provide an overview, based on current knowledge, on how phytochemicals, including epigallocatechin-3-gallate, can be considered as potential miRNAs modulator to improve efficacy of current cancer treatments.…”
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12736
Novel Therapies Boosting T Cell Immunity in Epstein Barr Virus-Associated Nasopharyngeal Carcinoma
Published 2020-06-01“…Its high morbidity rate is linked to both late-stage diagnosis and unresponsiveness to conventional anti-cancer treatments. Multiple aetiological factors have been described including environmental factors, genetics, and viral factors (Epstein Barr Virus, EBV), making NPC treatment that much more complex. …”
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12737
Chitosan–Hyaluronic Acid Nanoparticles for Active Targeting in Cancer Therapy
Published 2022-08-01“…Cancer is the most common cause of death worldwide; therefore, there is a need to discover novel treatment modalities to combat it. One of the cancer treatments is nanoparticle technology. Currently, nanoparticles have been modified to have desirable pharmacological effects by using chemical ligands that bind with their specific receptors on the surface of malignant cells. …”
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12738
“HLA-C: evolution, epigenetics, and pathological implications in the major histocompatibility complex”
Published 2023-07-01“…These alterations can manifest in diseases such as alopecia areata and psoriasis and can also impact susceptibility to cancer and the effectiveness of cancer treatments. By comprehending the intricate interplay between genetic and epigenetic factors that regulate HLA-C expression, researchers may develop novel strategies for preventing and treating diseases associated with HLA-C dysregulation.…”
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12739
Oxidative Damage as a Fundament of Systemic Toxicities Induced by Cisplatin—The Crucial Limitation or Potential Therapeutic Target?
Published 2023-09-01“…Despite the progress of pharmaceutical sciences and medicine and the successful application of other platinum complexes for the same purpose, cisplatin is still the therapy of choice in many cancers. Treatment for testicular, ovarian, head and neck, urothelial, cervical, esophageal, breast, and pulmonary malignancies is still unthinkable without the use of this drug. …”
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12740
Dendritic Cell-Based and Other Vaccination Strategies for Pediatric Cancer
Published 2019-09-01“…Moreover, in contrast to conventional cancer treatments such as chemotherapy, therapeutic cancer vaccines are designed to specifically target tumor cells and not healthy cells or tissues. …”
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