Chimeric antigen receptor T-cell as a significant player in the innovative treatment of hematological cancers by Karolina Makowska, Kinga Panuciak, Angelika Mastalerczyk, Emilia Nowicka, Michał Obel, Kamila Czyżak, Jan Lejman, Natalia Trąbka, Klaudia Jedlina, Katarzyna Pacek

“…CAR-T is a culmination of many years of research in the dynamically developing area of immunotherapy as a revolutionary therapy of hematological cancers treatments. State of knowledge: In order to explore the topic, analysis included research available in the PubMed database. …”
Get full text

New insights on the interplays between m6A modifications and microRNA or lncRNA in gastrointestinal cancers by Tao Su, Tao Su, Jiandong Liu, Nasha Zhang, Nasha Zhang, Teng Wang, Linyu Han, Suzhen Wang, Ming Yang, Ming Yang, Ming Yang, Ming Yang

“…Although there are still extensive studies on genome-wide screening of crucial lncRNAs or miRNAs involved in regulating m6A levels of mRNAs and disclosing differences on mechanisms of regulating m6A modification of lncRNAs, miRNAs or mRNAs in cancer cells, we believe that targeting m6A-related lncRNAs and miRNAs may provide novel options for gastrointestinal cancer treatments.…”
Get full text

Thread as a Low-Cost Material for Microfluidic Assays on Intact Tumor Slices by Maxwell Rumaner, Lisa Horowitz, Avital Ovadya, Albert Folch

“…Today, the need for new and effective cancer treatments is greater than ever, but unfortunately, the cost of developing new chemotherapy drugs has never been higher. …”
Get full text

Transcriptome Analysis of Human Endogenous Retroviruses at Locus-Specific Resolution in Non-Small Cell Lung Cancer by Alessandro La Ferlita, Rosario Distefano, Salvatore Alaimo, Joal D. Beane, Alfredo Ferro, Carlo M. Croce, Philip N. Tsichlis, Alfredo Pulvirenti, Giovanni Nigita

“…Despite the incredible efforts and recent advances in lung cancer treatments, patients affected by this condition still have a poor prognosis. …”
Get full text

Metabolic Reprogramming by Reduced Calorie Intake or Pharmacological Caloric Restriction Mimetics for Improved Cancer Immunotherapy by Erwan Eriau, Juliette Paillet, Guido Kroemer, Jonathan G. Pol

“…Caloric restriction and its mimetics induce autophagy to improve the efficacy of some cancer treatments that induce immunogenic cell death (ICD), a type of cellular demise that eventually elicits adaptive antitumor immunity. …”
Get full text

SERS Detection of Breast Cancer‐Derived Exosomes Using a Nanostructured Pt‐Black Template by Xinyue Li, Meysam Keshavarz, Panagiotis Kassanos, Zahra Kidy, Alfie Roddan, Eric Yeatman, Alex J. Thompson

“…Abstract At present, there are no cancer treatments that are both non‐invasive and highly accurate. …”
Get full text

Impact of deleterious passenger mutations on cancer progression by Korolev, Kirill Sergeevich, Sunyaev, Shamil R., McFarland, Christopher D., Kryukov, Gregory V., Mirny, Leonid A

“…Finally, we use our model to explore cancer treatments that exploit the load of passengers by either (i) increasing the mutation rate or (ii) exacerbating their deleterious effects. …”
Get full text
Get full text

Effect of Heat-Inactivated Clostridium sporogenes and Its Conditioned Media on 3-Dimensional Colorectal Cancer Cell Models by Bhave, Madhura Satish, Hassanbhai, Ammar Mansoor, Anand, Padmaja, Luo, Kathy Qian, Teoh, Swee Hin

“…Traditional cancer treatments, such as chemotherapy and radiation therapy continue to have limited efficacy due to tumor hypoxia. …”
Get full text
Get full text

Sickle erythrocytes target cytotoxics to hypoxic tumor microvessels and potentiate a tumoricidal response by Terman, DS, Viglianti, BL, Zennadi, R, Fels, D, Boruta, RJ, Yuan, H, Dreher, MR, Grant, G, Rabbani, ZN, Moon, EJ, Lan, L, Eble, J, Cao, Y, Sorg, B, Ashcraft, K, Palmer, G, Telen, MJ, Dewhirst, MW

“…Thus, the SSRBC appears to be a potent new tool for treatment of hypoxic solid tumors, which are notable for their resistance to existing cancer treatments.…”

The potential use of plant-derived saponins as a phytobiotic additive in poultry feed for production and health advancement: a comprehensive review by Alghirani, Mohamed M., Lim, Eric Teik Chung, Abdullah Jesse, Faez Firdaus, Sazili, Awis Qurni, Loh, Teck Chwen

“…Additionally, steroidal saponins have been commercialized as supplements for poultry, health foods for human consumption, and potential anti-cancer treatments. Therefore, the present review will critically shed light on the availability of different saponins and the influence on the production performance and immunopathology responses of poultry supplemented with different saponins extract. …”

Anxiety disorders and quality of life among patients with hematological cancer in a Malaysian hospital by Das, Priscilla, Awang, Hamidin, Md. Zain, Azhar, Naing, Khin Ohnmar@Noor Jan, Md Said, Salmiah, Khalid, Bahariah

“…Therefore flexible cancer treatments should include a referral to a health professional or psychiatrist who is able to address a patient's mental health status and quality of life.…”
Get full text
Get full text

Preparation, antioxidant potential and angiotensin converting enzyme (ACE) inhibitory activity of gum Arabic-stabilised magnesium orotate nanoparticles by Abdelkader, Hassani, Hussain, Siti Aslina, Abdullah, Norhafizah, Kamarudin, Suryani, Rosli, Rozita

“…Hence, MgOrGANPs may have great potential to be applied for cancer treatments.…”
Get full text

Ampelopsin E reduces the invasiveness of the triple negative breast cancer cell line, MDA-MB-231 by Tieng, Francis Yew Fu, Saiful Yazan, Latifah, Md Hashim, Nur Fariesha, Khaza'ai, Huzwah, Ahmat, Norizan, Gopalsamy, Banulata, Wibowo, Agustono

“…During metastasis, cancer cells are thought to form actin-rich protrusions, called invadopodia, which degrade the extracellular matrix. Current breast cancer treatments, particularly chemotherapy, comes with adverse effects like immunosuppression, resistance development and secondary tumour formation. …”
Get full text

Preparation, antioxidant potential and angiotensin converting enzyme (ACE) inhibitory activity of gum arabic-stabilized magnesium orotate nanoparticles by Abdelkader, Hassani, Hussain, Siti Aslina, Abdullah, Norhafizah, Kamarudin, Suryani, Rosli, Rozita

“…Hence, MgOrGANPs may have great potential to be applied for cancer treatments.…”
Get full text

An analysis of news media coverage of complementary and alternative medicine. by Billie Bonevski, Amanda Wilson, David A Henry

“…There was a statistically significant difference in cumulative mean scores (F = 3.72, p = 0.0001) according to the clinical outcome of interest with stories about cancer treatments (62%, 95% CI 54% to 70%) scoring highest and stories about treatments for children's behavioural and mental health concerns scoring lowest (31%, 95% CI 19% to 43%). …”
Get full text

Sexual Dysfunction of Patients with Diffuse Low-Grade Glioma: A Qualitative Review of a Neglected Concern by Arnaud Lombard, Hugues Duffau

“…As those patients are usually young and enjoy an active life, there is a need to assess more systematically the occurrence of SD in clinical routine, in order to adapt cancer treatments accordingly, to manage actively these troubles, and finally to improve patients’ QoL in the long run.…”
Get full text

Hemostasis and tumor immunity by Rachel Cantrell, Joseph S. Palumbo

“…A better understanding of these relationships will likely lead to strategies to make existing adaptive immune based therapies safer by decreasing thromboembolic risk and may also lead to novel targets to improve adaptive immune‐based cancer treatments.…”
Get full text

The ability of cancer-specific and generic preference-based instruments to discriminate across clinical and self-reported measures of cancer severities by Teckle Paulos, Peacock Stuart, McTaggart-Cowan Helen, van der Hoek Kim, Chia Stephen, Melosky Barb, Gelmon Karen

“…This raises concerns regarding the appropriateness of these instruments when comparing different cancer treatments within an economic evaluation framework.…”
Get full text

Microbes and Cancer: Friends or Faux? by Maria Manuel Azevedo, Cidália Pina-Vaz, Fátima Baltazar

“…Importantly, immunosuppressive cancer treatments increase the risk of infection, by decreasing the host defenses. …”
Get full text

Decisional Regret in Female Oncofertility Decision Making—An Integrative Narrative Review by Vânia Gonçalves

“…It is well established that fertility is an important issue for young women with cancer at reproductive age, as many have not initiated or completed their parenthood goals when diagnosed. Because cancer treatments may impair fertility, women face fertility decisions that are often complex and surrounded by uncertainty. …”
Get full text