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13001
K-nearest-neighbor algorithm to predict the survival time and classification of various stages of oral cancer: a machine learning approach [version 2; peer review: 2 approved]
Published 2023-11-01“…Background:For years now, cancer treatments have entailed tried-and-true methods. …”
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13002
Integrative oncology for breast cancer patients: introduction of an expert-based model
Published 2012-11-01“…Herbal medicines and dietary supplements, especially, may interfere with primary cancer treatments or have other detrimental effects. Thus, expertise in this highly specialized field of integrative medicine should be available to patients so that they can be advised about the benefits and negative effects of such preparations and practices.…”
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13003
Immunomodulatory, Antioxidant, Anticancer, and Pharmacokinetic Activity of Ulvan, a Seaweed-Derived Sulfated Polysaccharide: An Updated Comprehensive Review
Published 2023-05-01“…The inefficiency of conventional cancer treatments as a result of drug resistance, nontargeted delivery, and chemotherapy-related negative side effects has caused bioactive phytochemicals to come into focus. …”
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13004
Xenogeneic cell therapy provides a novel potential therapeutic option for cancers by restoring tissue function, repairing cancer wound and reviving anti-tumor immune responses
Published 2018-01-01“…Abstract Conventional cancer treatments such as surgery, radiotherapy, chemotherapy and targeted therapy, not only destruct tumors, but also injure the normal tissues, resulting in limited efficacy. …”
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13005
KLF4 Regulates Metabolic Homeostasis in Response to Stress
Published 2021-04-01“…Collectively, these results relate KLF4 to non-Warburg metabolic behaviors that support its role as a tumor suppressor and could make KLF4 a target for new cancer treatments.…”
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13006
Combination of ethyl acetate fraction from Calotropis gigantea stem bark and sorafenib induces apoptosis in HepG2 cells.
Published 2024-01-01“…Our results present valuable knowledge to support the development of anticancer regimens derived from the CGEtOAc with the chemotherapeutic agent sorafenib, both of which were administered at half-IC50, which may minimize the toxic implications of cancer treatments while improving the therapeutic effectiveness toward future medical applications.…”
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13007
Identification of a Gene Signature That Predicts Dependence upon YAP/TAZ-TEAD
Published 2024-02-01“…Targeted therapies are effective cancer treatments when accompanied by accurate diagnostic tests that can help identify patients that will respond to those therapies. …”
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13008
Survival of Lung Cancer Patients by Histopathology in Taiwan from 2010 to 2016: A Nationwide Study
Published 2022-09-01“…Together with immune therapy, the landscape of lung cancer treatments is changing.…”
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13009
How Do We Taper and Discontinue Opioids in Cancer Patients? Considerations from the Activities of a Palliative Care Team at a University Hospital
Published 2021-09-01“…Background: The more the cancer treatments progress, the more the needs increase to taper and discontinue opioids in cancer patients. …”
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13010
Metabolic engineering of <it>Agrobacterium </it>sp. strain ATCC 31749 for production of an α-Gal epitope
Published 2010-01-01“…<p>Abstract</p> <p>Background</p> <p>Oligosaccharides containing a terminal Gal-α1,3-Gal moiety are collectively known as α-Gal epitopes. α-Gal epitopes are integral components of several medical treatments under development, including flu and HIV vaccines as well as cancer treatments. The difficulty associated with synthesizing the α-Gal epitope hinders the development and application of these treatments due to the limited availability and high cost of the α-Gal epitope. …”
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13011
Quantum Dots as a Good Carriers of Unsymmetrical Bisacridines for Modulating Cellular Uptake and the Biological Response in Lung and Colon Cancer Cells
Published 2021-02-01“…Nanotechnology-based drug delivery provides a promising area for improving the efficacy of cancer treatments. Therefore, we investigate the potential of using quantum dots (QDs) as drug carriers for antitumor unsymmetrical bisacridine derivatives (UAs) to cancer cells. …”
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13012
Exploring animal models in oral cancer research and clinical intervention: A critical review
Published 2023-07-01“…To induce cancer in rodents, xenografts are often used, but companion animals with spontaneous tumours are underutilized for rapid advancement in human and veterinary cancer treatments. Like humans with cancer, companion animals exhibit biological behaviour, treatment responses, and cytotoxic agent responses similar to humans. …”
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13013
Epigenomic perturbation of novel EGFR enhancers reduces the proliferative and invasive capacity of glioblastoma and increases sensitivity to temozolomide
Published 2023-10-01“…This study demonstrates how CRISPR/Cas9-based perturbation of enhancers can be used to modulate the expression of key cancer genes, which can help improve the effectiveness of existing cancer treatments and potentially the prognosis of difficult-to-treat cancers such as glioblastoma.…”
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13014
COVID-19 Vaccination in Cancer Patients: A Review Article
Published 2022-06-01“…Generally, the vaccine should be given before starting the chemotherapy if possible or in between chemotherapy cycles and away from nadir phase. For other cancer treatments, it is recommended to give the vaccine when there is evidence of blood count recovery. …”
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13015
A Promotive Process of Resource Gain Against Harsh and Inconsistent Discipline in Mothers Coping With Breast Cancer: A Serial Mediation Model
Published 2022-06-01“…A sample of 100 Israeli mothers receiving breast cancer treatments was recruited through social media. The participants completed online self-report questionnaires. …”
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13016
Cancer Detection Using a New Hybrid Method Based on Pattern Recognition in MicroRNAs Combining Particle Swarm Optimization Algorithm and Artificial Neural Network
Published 2024-03-01“…This method can serve as a supplementary tool for cancer diagnosis and potentially aid in developing personalized cancer treatments.…”
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13017
Preparation and Characterization of Gold Nanorods Coated with Gellan Gum and Lipoic Acid
Published 2020-11-01“…Gold nanorods (AuNRs) can combine therapeutic hyperthermia with diagnostic features, representing a smart choice to address personalized cancer treatments. In this regard, a crucial quest is the selection of the right biocompatible coating agent able to stabilize them in the physiological environment, further endowing the possibility to load bioactive molecules and/or targeting moieties. …”
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13018
Premature ovarian insufficiency in female adolescent and young adult survivors of non-gynecological cancers: a population-based cohort study
Published 2023-01-01“…Previous research has shown that there is a higher risk of premature ovarian insufficiency in adolescent and young adult cancer survivors, due to the toxicity of cancer treatments on reproductive organs. Prior research was limited in its applicability by having small sample sizes, only including childhood cancer, excluding young adults, and studying fewer types of cancer. …”
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13019
Advances in Preclinical Research Models of Radiation-Induced Cardiac Toxicity
Published 2020-02-01“…An understanding of the biological pathways and mechanisms involved in normal tissue toxicity from RT will improve future cancer treatments by reducing the risk of long-term side effects. …”
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13020
Sodium-glucose cotransporter 2 (SGLT2) inhibitor initiation and hepatocellular carcinoma prognosis.
Published 2022-01-01“…Further, we found that SGLT2 inhibitor initiation was associated with a lower risk mortality risk ranging from 14% to 60% regardless of patient demographic variables, tumor characteristics, and cancer treatments.<h4>Conclusion</h4>Our large SEER-Medicare linked data study indicates that SGLT2 inhibitor initiation was associated with improved overall survival of HCC patients with pre-existing type 2 diabetes compared with no SGLT2 inhibitor use. …”
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