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13121
Therapeutic Role of Carotenoids in Blood Cancer: Mechanistic Insights and Therapeutic Potential
Published 2022-05-01“…To cope with these challenges, treatment strategies from phyto-medicine scaffolds have been evaluated for blood cancer treatments. Carotenoids represent a versatile class of phytochemical that offer therapeutic efficacy in the treatment of cancer, and specifically blood cancer. …”
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13122
Antioxidants as precision weapons in war against cancer chemotherapy induced toxicity – Exploring the armoury of obscurity
Published 2018-02-01“…Among the conventional cancer treatments, chemotherapy is most frequently carried out to treat malignant cancer rather than localised lesions which is amenable to surgery and radiotherapy. …”
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13123
Integration of Complementary Medicine in Supportive Cancer Care: Survey of Healthcare Providers’ Perspectives
Published 2023-09-01“…Implications to Nursing: CTM usage does involve some risks, so HCPs should be trained in why cancer patients choose to integrate CTM with conventional cancer treatments and how they can safely help them do so.…”
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13124
Luteolin Inhibits Breast Cancer Stemness and Enhances Chemosensitivity through the Nrf2-Mediated Pathway
Published 2021-10-01“…Luteolin constitutes a potential agent for use in cancer stemness-targeted breast cancer treatments.…”
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13125
Case report: Metastatic urothelial cancer with an exceptional response to immunotherapy and comprehensive understanding of the tumor and the tumor microenvironment
Published 2022-10-01“…The tumor microenvironment (TME) is recognized as a key player in tumor progression and the response to certain anti-cancer treatments. This study aims to investigate the mechanism of response using integrated genomic and transcriptomic profiling of a UC patient who was part of the KEYNOTE-045 trial and showed an exceptional response to pembrolizumab. …”
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13126
A Shiga Toxin B-Subunit-Based Lectibody Boosts T Cell Cytotoxicity towards Gb3-Positive Cancer Cells
Published 2023-07-01“…The lectibody developed in this study, therefore, highlights the potential that lectibodies and lectins in general have for usage in immunotherapeutic approaches to boost the efficacy of established cancer treatments.…”
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13127
Oxygen Nanocarriers for Improving Cardioplegic Solution Performance: Physico-Chemical Characterization
Published 2023-06-01“…Nanocarriers for oxygen delivery have been the focus of extensive research to ameliorate the therapeutic effects of current anti-cancer treatments and in the organ transplant field. In the latter application, the use of oxygenated cardioplegic solution (CS) during cardiac arrest is certainly beneficial, and fully oxygenated crystalloid solutions may be excellent means of myocardial protection, albeit for a limited time. …”
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13128
Cerebrovascular accident in a child with precursor B-cell acute lymphoblastic leukemia and coronavirus disease 2019: a case report
Published 2022-12-01“…A rare event in this report is stroke following COVID-19 disease in a patient with an immunocompromised background due to leukemia and anti-cancer treatments. Case presentation A 6-year-old iranian girl with precursor B-cell leukemia receiving vincristine therapy presented with fever and absolute neutrophil count < 500. …”
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13129
Near‐infrared‐induced drug release from antibody–drug double conjugates exerts a cytotoxic photo‐bystander effect
Published 2022-09-01“…Abstract Ideal cancer treatments specifically target and eradicate tumor cells without affecting healthy cells. …”
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13130
Role of advanced cardiovascular imaging in chemotherapy-induced cardiotoxicity
Published 2023-04-01“…The development of cardiotoxicity induced by cancer treatments has emerged as a significant clinical problem, both in the short run, as it may influence drug administration in chemotherapeutic protocols, and in the long run, because it may determine adverse cardiovascular outcomes in survivors of various malignant diseases. …”
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13131
Synthesis, Leishmanicidal, Trypanocidal, Antiproliferative Assay and Apoptotic Induction of (2-Phenoxypyridin-3-yl)naphthalene-1(2<i>H</i>)-one Derivatives
Published 2022-08-01“…Based on the structural analysis, these chalcones represent new compounds potentially useful for <i>Leishmania</i>, <i>Trypanosoma</i> <i>cruzi</i>, and some cancer treatments.…”
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13132
The Efficacy of Photobiomodulation Therapy in Improving Tissue Resilience and Healing of Radiation Skin Damage
Published 2021-12-01“…The results from this study support future mechanistic lab studies and controlled human clinical studies to utilize this innovative therapy in managing side effects from radiation cancer treatments.…”
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13133
Symptom Management and Quality of Life of Breast Cancer Patients Using Acupuncture-Related Therapies and Herbal Medicine: A Scoping Review
Published 2022-09-01“…The side effects associated with breast cancer treatments often reduce the patients’ quality of life. …”
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13134
A comprehensive review of the anticancer effects of decursin
Published 2024-02-01“…With the increasing resistance to current anticancer drugs, efforts have been made to develop effective cancer treatments. Currently, natural products are considered promising cancer therapeutic agents due to their potent anticancer activity and low intrinsic toxicity. …”
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13135
A Miniaturized Platform for Multiplexed Drug Response Imaging in Live Tumors
Published 2021-02-01“…By observing the activity of anti-cancer agents directly in tumors, there is potential to greatly expand our understanding of drug response and develop more personalized cancer treatments. Implantable microdevices (IMD) have been recently developed to deliver microdoses of chemotherapeutic agents locally into confined regions of live tumors; the tissue can be subsequently removed and analyzed to evaluate drug response. …”
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13136
Rapamycin Plus Doxycycline Combination Affects Growth Arrest and Selective Autophagy-Dependent Cell Death in Breast Cancer Cells
Published 2021-07-01“…Based on these results, we suggest considering inducing metabolic stress and targeting mTOR hyperactivity and mitochondrial functions in combined anti-cancer treatments.…”
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13137
Suicide rates among patients with first and second primary cancer
Published 2023-01-01“…Abstract Aims With advancements in cancer treatments, the survival rates of patients with their first primary cancer (FPC) have increased, resulting in a rise in the number of patients with second primary cancer (SPC). …”
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13138
KPNB1 Inhibitor Importazole Reduces Ionizing Radiation-Increased Cell Surface PD-L1 Expression by Modulating Expression and Nuclear Import of IRF1
Published 2021-05-01“…Recent reports indicate that anti-cancer treatments, such as radiation therapy, increase PD-L1 expression on the surface of tumor cells. …”
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13139
Targeting the retinoic acid signaling pathway as a modern precision therapy against cancers
Published 2023-08-01“…In addition to the genomic effects of ATRA, we also highlighted the role of ATRA in non-canonical mechanisms as an immune checkpoint inhibitor, thus targeting the immune oncological perspective of cancer treatments in the current era. The role of ATRA in activating independent mechanisms is also explained in this review. …”
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13140
The Potential of DHA as Cancer Therapy Strategies: A Narrative Review of In Vitro Cytotoxicity Trials
Published 2023-04-01“…Docosahexaenoic acid (DHA), also known as omega-3 (<i>n</i>-3) polyunsaturated fatty acid (PUFA), is a natural compound that has demonstrated pharmacological activity against several malignant neoplasms. Available cancer treatments cause side effects, affect healthy cells, reduce the quality of life of patients and may cause resistance to antineoplastics. …”
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