Exploring Herbal Medicine Use during Palliative Cancer Care: The Integrative Physician as a Facilitator of Pharmacist–Patient–Oncologist Communication by Noah Samuels, Eran Ben-Arye

“…This collaboration provides patients with a nonjudgmental and multidisciplinary approach to integrative medicine, echoing their own health-belief models of care during conventional cancer treatments. The role of the integrative physician is to facilitate this process, working with oncologists and pharmacists in the fostering of patient-centered palliative care, while ensuring a safe and effective treatment environment. …”
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Travel, Treatment Choice, and Survival Among Breast Cancer Patients: A Population-Based Analysis by Colleen F. Longacre, Hannah T. Neprash, Nathan D. Shippee, Todd M. Tuttle, Beth A. Virnig

“…Conclusions: We report two breast cancer treatments with different clinical and travel implications to show the association between travel distance, treatment decisions, and receipt of guideline-concordant treatment. …”
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Dual Acting Polymeric Nano-Aggregates for Liver Cancer Therapy by Wejdan Al-Shakarchi, Ali Alsuraifi, Anthony Curtis, Clare Hoskins

“…Liver cancer treatments are often hindered by poor drug physicochemical properties, hence there is a need for improvement in order to increase patient survival and outlook. …”
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Store-operated calcium entry via ORAI1 regulates doxorubicin-induced apoptosis and prevents cardiotoxicity in cardiac fibroblasts by Hiroko Nemoto, Masanari Umemura, Fumina Suzuki, Akane Nagasako, Kagemichi Nagao, Yuko Hidaka, Rina Nakakaji, Keiji Uchida, Shinichi Suzuki, Munetaka Masuda, Yoshihiro Ishikawa

“…Despite exhibiting cardiotoxicity, doxorubicin (DOX) is widely used for cancer treatments. Cardiac fibroblasts (CFs) are important in the pathogenesis of heart failure. …”
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The identification of tumor antigens and immune subtypes based on the development of immunotherapies targeting head and neck squamous cell carcinomas resulting from periodontal dis... by Yangju Fu, Yongbo Zheng

“…Among cancer treatments, immunotherapy is considered a promising strategy. …”
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Enhanced supportive care for advanced cancer patients: study protocol for a randomized controlled trial by Yun Young Choi, Sun Young Rha, Sungkun Cho, Hye Sun Lee, Bomi Hong, Jiyeon Lee

“…Abstract Background Early palliative care along with standard cancer treatments is recommended in current clinical guidelines to improve the quality of life and survival of cancer patients. …”
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Investigation of <i>Staphylococcus aureus</i> Biofilm-Associated Toxin as a Potential Squamous Cell Carcinoma Therapeutic by Zi Xin Ong, Bavani Kannan, Anthony R. J. Phillips, David L. Becker

“…Compared to traditional cancer treatments, the use of bacteria-derived compounds as cancer therapeutics could offer a higher degree of specificity, with minimal off-target effects. …”
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Antioxidant, Enzyme, and H₂O₂-Triggered Melanoma Targeted Mesoporous Organo-Silica Nanocomposites for Synergistic Cancer Therapy by Hyung Woo Choi, Jae Hyun Lim, Taewook Kang, Bong Geun Chung

“…The multi-stimuli responsive drug delivery system has recently attracted attention in cancer treatments, since it can reduce several side effects and enhance cancer therapeutic efficacy. …”
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Role of YY1 in the Regulation of Anti-Apoptotic Gene Products in Drug-Resistant Cancer Cells by Megan Jung, Indy Bui, Benjamin Bonavida

“…In the last decade, several milestones in cancer treatments were accomplished, such as specific targeting agents or revitalizing the dormant anti-tumor immune response. …”
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A single-armed proof-of-concept study of Lymfit: A personalized, virtual exercise intervention to improve health outcomes in lymphoma survivors in the pandemic. by Christopher Angelillo, Wing Lam Tock, Matthew Salaciak, Ryan E R Reid, Ross E Andersen, Christine Maheu, Nathalie A Johnson

“…Mounting evidence indicates that physical activities are highly therapeutic in mitigating the short- and long-term side effects of cancer treatments. Yet, lymphoma survivors' participation in physical activities remains suboptimal, which has been further exacerbated by the deleterious effects of isolation during the COVID-19 pandemic. …”
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Thymoquinone, an active ingredient of Black Seed (Nigela saliva) induces distinct apoptotic pathways in C33A and Siha Cervical Cancer Cell Lines) by Ichwan, Solachuddin JA, Al-Ani, Imad Matloub Dally, Suriyah, Wastuti, Muhammad, Taher

“…These results support further research in exploring the potential clinical usefulness of TQ for cervical cancers treatment. …”
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Evaluation of 2D and 3D ultrasound tracking algorithms and impact on ultrasound‐guided liver radiotherapy margins by De Luca, V, Banerjee, J, Hallack, A, Kondo, S, Makhinya, M, Nouri, D, Royer, L, Cifor, A, Dardenne, G, Goksel, O, Gooding, M, Klink, C, Krupa, A, Le Bras, A, Marchal, M, Moelker, A, Niessen, W, Papiez, B, Rothberg, A, Schnabel, J, Van Walsum, T, Harris, E, Bell, L, Tanner, C

“…<br/><strong>Purpose: </strong>Compensation for respiratory motion is important during abdominal cancer treatments. In this work we report the results of the 2015 MICCAI Challenge on Liver Ultrasound Tracking and extend the 2D results to relate them to clinical relevance in form of reducing treatment margins and hence sparing healthy tissues, while maintaining full duty cycle.…”

The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes. by Teo, M, Landi, D, Taylor, C, Elliott, F, Vaslin, L, Cox, D, Hall, J, Landi, S, Bishop, D, Kiltie, A

“…If validated, these findings may give further insight into the biology of bladder carcinogenesis, allow testing of the RAD51 SNP as a potential predictive biomarker and also reveal potential targets for new cancer treatments.…”

Phase I study of humanized monoclonal antibody AVE1642 directed against the type 1 insulin-like growth factor receptor (IGF-1R), administered in combination with anticancer therapi... by Macaulay, V, Middleton, M, Protheroe, A, Tolcher, A, Dieras, V, Sessa, C, Bahleda, R, Blay, J, LoRusso, P, Mery-Mignard, D, Soria, J

“…This study assessed the safety, pharmacokinetics (PK), and tolerability of humanized IGF-1R antibody AVE1642 with other cancer treatments. PATIENTS: Patients with advanced solid tumors received three weekly AVE1642 dosed at 6 mg/kg, chosen following previous study, with 75 (cohort A) or 100 mg/m(2) (B) docetaxel, 1250 mg/m(2) gemcitabine/100 mg erlotinib (C1), or 60 mg/m(2) doxorubicin (D1). …”

When are breast cancer patients at highest risk of venous thromboembolism? A cohort study using English health care data by Walker, A, West, J, Card, T, Crooks, C, Kirwan, C, Grainge, M

“…However, no previous epidemiologic studies have investigated the relative impact of breast cancer treatments in a time-dependent manner. We aimed to determine the impact of breast cancer stage, biology, and treatment on the absolute and relative risks of VTE by using several recently linked data sources from England. …”

Computer-aided drug discovery of Myc-Max inhibitors as potential therapeutics for prostate cancer by Carabet, L, Lallous, N, Leblanc, E, Ban, F, Morin, H, Lawn, S, Ghaidi, F, Lee, J, Mills, I, Gleave, M, Rennie, P, Cherkasov, A

“…These findings lay a foundation for developing more potent, specific and clinically optimized Myc-Max inhibitors that may serve as promising therapeutics, alone or in combination with current anti-cancer treatments, for treatment of specific phenotypes or heterogeneous tumors.…”

Chemical composition and cytotoxic properties of Clinacanthus nutans root extracts by Teoh, Peik Lin, Cheng, Angelina Yi Fang, Liau, Monica, Lem, Fui Fui, Grace P. Kaling, Chua, Fern Nie, Cheong, Bo Eng

“…In Malaysia, it has been widely claimed to be effective in various cancer treatments but scientific evidence is lacking. …”
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Identification of novel cytotoxic peptide KENPVLSLVNGMF from marine sponge xestospongia testudinaria, with characterization of stability in human serum by Quah, Yixian, Mohd. Ismail, Nor Ismaliza, Ooi, Jillian Lean Sim, Affendi, Yang Amri, Abd. Manan, Fazilah, Wong, Fai Chu, Chai, Tsun Thai

“…Marine sponges hold great promise as a source of potent cytotoxic peptides with future applications in cancer treatments. This study aimed to purify and identify cytotoxic peptides from the protein hydrolysates of the giant barrel sponge Xestospongia testudinaria, guided by a cytotoxicity assay based on the human cervical cancer cell line (HeLa). …”

Hearing loss after exposure to vincristine and platinum-based chemotherapy among childhood cancer survivors by Sven Strebel, Luzius Mader, Philippa Jörger, Nicolas Waespe, Seraina Uhlmann, Nicolas von der Weid, Marc Ansari, Claudia E. Kuehni

“…We suggest future studies investigate the underlying mechanism and causality among CCS without exposure to other ototoxic cancer treatments.…”
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In Vitro Cytotoxic Activity of African Plants: A Review by Isabel Canga, Pedro Vita, Ana Isabel Oliveira, María Ángeles Castro, Cláudia Pinho

“…The high mortality rate and adverse effects associated with cancer treatments have encouraged the search for novel plant-based drugs, thus, some African plants have been studied in recent years as a source of molecules with proven cytotoxicity. …”
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