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13221
Exploring Herbal Medicine Use during Palliative Cancer Care: The Integrative Physician as a Facilitator of Pharmacist–Patient–Oncologist Communication
Published 2020-12-01“…This collaboration provides patients with a nonjudgmental and multidisciplinary approach to integrative medicine, echoing their own health-belief models of care during conventional cancer treatments. The role of the integrative physician is to facilitate this process, working with oncologists and pharmacists in the fostering of patient-centered palliative care, while ensuring a safe and effective treatment environment. …”
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13222
Travel, Treatment Choice, and Survival Among Breast Cancer Patients: A Population-Based Analysis
Published 2021-01-01“…Conclusions: We report two breast cancer treatments with different clinical and travel implications to show the association between travel distance, treatment decisions, and receipt of guideline-concordant treatment. …”
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13223
Dual Acting Polymeric Nano-Aggregates for Liver Cancer Therapy
Published 2018-05-01“…Liver cancer treatments are often hindered by poor drug physicochemical properties, hence there is a need for improvement in order to increase patient survival and outlook. …”
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13224
Store-operated calcium entry via ORAI1 regulates doxorubicin-induced apoptosis and prevents cardiotoxicity in cardiac fibroblasts
Published 2022-01-01“…Despite exhibiting cardiotoxicity, doxorubicin (DOX) is widely used for cancer treatments. Cardiac fibroblasts (CFs) are important in the pathogenesis of heart failure. …”
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13225
The identification of tumor antigens and immune subtypes based on the development of immunotherapies targeting head and neck squamous cell carcinomas resulting from periodontal dis...
Published 2023-08-01“…Among cancer treatments, immunotherapy is considered a promising strategy. …”
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13226
Enhanced supportive care for advanced cancer patients: study protocol for a randomized controlled trial
Published 2022-12-01“…Abstract Background Early palliative care along with standard cancer treatments is recommended in current clinical guidelines to improve the quality of life and survival of cancer patients. …”
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13227
Investigation of <i>Staphylococcus aureus</i> Biofilm-Associated Toxin as a Potential Squamous Cell Carcinoma Therapeutic
Published 2024-01-01“…Compared to traditional cancer treatments, the use of bacteria-derived compounds as cancer therapeutics could offer a higher degree of specificity, with minimal off-target effects. …”
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13228
Antioxidant, Enzyme, and H<sub>2</sub>O<sub>2</sub>-Triggered Melanoma Targeted Mesoporous Organo-Silica Nanocomposites for Synergistic Cancer Therapy
Published 2022-10-01“…The multi-stimuli responsive drug delivery system has recently attracted attention in cancer treatments, since it can reduce several side effects and enhance cancer therapeutic efficacy. …”
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13229
Role of YY1 in the Regulation of Anti-Apoptotic Gene Products in Drug-Resistant Cancer Cells
Published 2023-08-01“…In the last decade, several milestones in cancer treatments were accomplished, such as specific targeting agents or revitalizing the dormant anti-tumor immune response. …”
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13230
A single-armed proof-of-concept study of Lymfit: A personalized, virtual exercise intervention to improve health outcomes in lymphoma survivors in the pandemic.
Published 2024-01-01“…Mounting evidence indicates that physical activities are highly therapeutic in mitigating the short- and long-term side effects of cancer treatments. Yet, lymphoma survivors' participation in physical activities remains suboptimal, which has been further exacerbated by the deleterious effects of isolation during the COVID-19 pandemic. …”
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13231
Thymoquinone, an active ingredient of Black Seed (Nigela saliva) induces distinct apoptotic pathways in C33A and Siha Cervical Cancer Cell Lines)
Published 2012“…These results support further research in exploring the potential clinical usefulness of TQ for cervical cancers treatment. …”
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Proceeding Paper -
13232
Evaluation of 2D and 3D ultrasound tracking algorithms and impact on ultrasound‐guided liver radiotherapy margins
Published 2018“…<br/><strong>Purpose: </strong>Compensation for respiratory motion is important during abdominal cancer treatments. In this work we report the results of the 2015 MICCAI Challenge on Liver Ultrasound Tracking and extend the 2D results to relate them to clinical relevance in form of reducing treatment margins and hence sparing healthy tissues, while maintaining full duty cycle.…”
Journal article -
13233
The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes.
Published 2012“…If validated, these findings may give further insight into the biology of bladder carcinogenesis, allow testing of the RAD51 SNP as a potential predictive biomarker and also reveal potential targets for new cancer treatments.…”
Journal article -
13234
Phase I study of humanized monoclonal antibody AVE1642 directed against the type 1 insulin-like growth factor receptor (IGF-1R), administered in combination with anticancer therapi...
Published 2013“…This study assessed the safety, pharmacokinetics (PK), and tolerability of humanized IGF-1R antibody AVE1642 with other cancer treatments. PATIENTS: Patients with advanced solid tumors received three weekly AVE1642 dosed at 6 mg/kg, chosen following previous study, with 75 (cohort A) or 100 mg/m(2) (B) docetaxel, 1250 mg/m(2) gemcitabine/100 mg erlotinib (C1), or 60 mg/m(2) doxorubicin (D1). …”
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13235
When are breast cancer patients at highest risk of venous thromboembolism? A cohort study using English health care data
Published 2016“…However, no previous epidemiologic studies have investigated the relative impact of breast cancer treatments in a time-dependent manner. We aimed to determine the impact of breast cancer stage, biology, and treatment on the absolute and relative risks of VTE by using several recently linked data sources from England. …”
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13236
Computer-aided drug discovery of Myc-Max inhibitors as potential therapeutics for prostate cancer
Published 2018“…These findings lay a foundation for developing more potent, specific and clinically optimized Myc-Max inhibitors that may serve as promising therapeutics, alone or in combination with current anti-cancer treatments, for treatment of specific phenotypes or heterogeneous tumors.…”
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13237
Chemical composition and cytotoxic properties of Clinacanthus nutans root extracts
Published 2017“…In Malaysia, it has been widely claimed to be effective in various cancer treatments but scientific evidence is lacking. …”
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13238
Identification of novel cytotoxic peptide KENPVLSLVNGMF from marine sponge xestospongia testudinaria, with characterization of stability in human serum
Published 2018“…Marine sponges hold great promise as a source of potent cytotoxic peptides with future applications in cancer treatments. This study aimed to purify and identify cytotoxic peptides from the protein hydrolysates of the giant barrel sponge Xestospongia testudinaria, guided by a cytotoxicity assay based on the human cervical cancer cell line (HeLa). …”
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13239
Hearing loss after exposure to vincristine and platinum-based chemotherapy among childhood cancer survivors
Published 2023-01-01“…We suggest future studies investigate the underlying mechanism and causality among CCS without exposure to other ototoxic cancer treatments.…”
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13240
In Vitro Cytotoxic Activity of African Plants: A Review
Published 2022-08-01“…The high mortality rate and adverse effects associated with cancer treatments have encouraged the search for novel plant-based drugs, thus, some African plants have been studied in recent years as a source of molecules with proven cytotoxicity. …”
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Article