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13461
Building a Better Defense: Expanding and Improving Natural Killer Cells for Adoptive Cell Therapy
Published 2024-03-01“…Natural killer (NK) cells have gained attention as a promising adoptive cell therapy platform for their potential to improve cancer treatments. NK cells offer distinct advantages over T-cells, including major histocompatibility complex class I (MHC-I)-independent tumor recognition and low risk of toxicity, even in an allogeneic setting. …”
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13462
Time-related survival prediction in molecular subtypes of breast cancer using time-to-event deep-learning-based models
Published 2023-06-01“…Future clinical trials should further explore the response of different molecular subtypes to treatment in order to optimize the efficacy of breast cancer treatments.…”
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13463
Tumor infiltrating leukocyte density is independent of tumor grade and molecular subtype in aggressive breast cancer of Western Kenya
Published 2017-08-01“…Future research is required to determine if the aberrant recruitment of TILs to tumors contributes to cancer progression and response to cancer treatments.…”
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13464
Changes in Body Weight, Body Composition, Phase Angle, and Resting Metabolic Rate in Male Patients with Stage IV Non-Small-Cell Lung Cancer Undergoing Therapy
Published 2022-12-01“…<i>Background and Objectives</i>: Cancer treatments can adversely influence body weight status, body composition, phase angle (PhA), and resting metabolic rate (RMR), which could possibly affect disease course. …”
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13465
Improving the diagnosis of cancer in primary care: a feasibility economic analysis of the ThinkCancer! study.
Published 2022-03-01“…Primary care interventions to expedite the diagnosis of symptomatic cancer have the potential to reduce large costs to the NHS and improve patient and carer outcomes as later stage cancer treatments are often longer, more aggressive to patients, with larger associated healthcare costs compared to earlier stage treatment. …”
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13466
Honeybee Venom Synergistically Enhances the Cytotoxic Effect of CNS Drugs in HT-29 Colon and MCF-7 Breast Cancer Cell Lines
Published 2022-02-01“…Overall, the present study corroborates the enormous bioactive potential of honeybee venom for colon and breast cancer treatments, both alone and in combination with chemotherapy or repurposed drugs.…”
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13467
Digital Life Coaching During Stem Cell Transplantation: Development and Usability Study
Published 2022-03-01“…ConclusionsDLC may be feasible for older patients during intensive hospital-based cancer treatments such as autologous SCT for multiple myeloma. …”
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13468
Oncolytic activity of Newcastle disease virus strain AF2240 in hypoxic cancer cells
Published 2018“…Solid tumors have different microenvironment that can influence the capability of cancer treatments. Cancer cells in low oxygen condition or hypoxia, present an obstacle as they are more resistant towards chemotherapy and radiotherapy. …”
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13469
A 16-year bicentric retrospective analysis of ovarian tissue cryopreservation in pediatric units: indications, results, and outcome
Published 2023-08-01“…BackgroundCancer treatments of the last decades improve the survival rate of children and adolescents. …”
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13470
Clinical and radiological features associated with EGFR mutation in non-small-cell lung cancer: a study of 149 cases
Published 2023-10-01“…Tumor cells with EGFR mutations are very sensitive to cancer treatments called "Targeted Therapies." The search for EGFR mutations requires lung biopsies. …”
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13471
Coping After Breast Cancer: Protocol for a Randomized Controlled Trial of Stress Management eHealth Interventions
Published 2023-05-01“…If 1 or both interventions prove to be effective in reducing stress and improving psychosocial and physical complains, the StressProffen eHealth interventions could be beneficial, inexpensive, and easily implementable tools for breast cancer survivors when coping with late effects after cancer and cancer treatments. Trial RegistrationClinicaltrials.gov NCT04480203; https://clinicaltrials.gov/ct2/show/NCT04480203 International Registered Report Identifier (IRRID)DERR1-10.2196/47195…”
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13472
Comprehensive Transcriptome Analysis Reveals the Distinct Gene Expression Patterns of Tumor Microenvironment in HPV-Associated and HPV-Non Associated Tonsillar Squamous Cell Carcin...
Published 2023-11-01“…Understanding the interaction between cancer inflammation, immunity, oncogenes, and tumor suppressor genes is essential for developing effective cancer treatments. This study aimed to gain a comprehensive understanding of the transcriptomes of the TME in TSCC, both associated with human papillomavirus (HPV) and not associated with HPV. …”
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13473
Early reduction in cardiorespiratory fitness and diastolic reserve following radiation therapy for lung cancer
Published 2024-03-01“…Cardiorespiratory fitness (CRF) is an independent predictor of cardiovascular, cancer-related, and overall mortality and may serve as a sensitive measure of subclinical cardiac toxicity following anti-cancer treatments. Prior work has demonstrated a significant relationship between reduced CRF and impaired left-ventricular (LV) diastolic reserve in cancer survivors following thoracic radiotherapy. …”
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13474
Exploring pyrrolidinyl-spirooxindole natural products as promising platforms for the synthesis of novel spirooxindoles as EGFR/CDK2 inhibitors for halting breast cancer cells
Published 2024-02-01“…Cancer represents a global challenge, and the pursuit of developing new cancer treatments that are potent, safe, less prone to drug resistance, and associated with fewer side effects poses a significant challenge in cancer research and drug discovery. …”
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13475
Antioxidant activities, polyphenolic profile and chemopreventive properties of Cyphomandra betacea L. ethanolic extract on human breast and liver adenocarcinoma cells
Published 2016“…The synergistic combination of tamarillo with commercial chemotherapy drug opens a new possible approach in the cancer treatments that are more effective and less toxic effect.…”
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13476
Energy Metabolism, Metabolite, and Inflammatory Profiles in Human Ex Vivo Adipose Tissue Are Influenced by Obesity Status, Metabolic Dysfunction, and Treatment Regimes in Patients...
Published 2023-03-01“…This study demonstrates that the adipose secretome in OAC patients is enriched with mediators that could prime the tumour microenvironment to aid tumour progression and attenuate responses to conventional cancer treatments, an effect which appears to be augmented by obesity and metabolic dysfunction and exposure to different treatment regimes.…”
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13477
Histological and safety evaluation of cockle shell-derived CaCO₃ nanoparticle loaded with doxorubicin in dogs
Published 2018“…Detrimental tissue effects are associated with chemotherapeutics, despite research progress in cancer treatments. Difficulties are still encountered with tumour targeting due to cancer structural complexity. …”
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13478
Autologous Tumor-Infiltrating Lymphocyte Mono-Therapy Can Rapidly Shrank Tumor in Asian Patient with Stage III/IV Cervical Cancer: Two Cases Report
Published 2024-01-01“…Trial registration number: NCT05366478.Keywords: tumor-infiltrating lymphocytes, clinical response, immune response, metastatic cervical cancer, treatment…”
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