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401
3-Chloropropane-1,2-diol (3-MCPD) in soy sauce: A review on the formation, reduction, and detection of this potential carcinogen
Published 2015“…There are 3 types of soy sauce: fermented, acid-hydrolyzed vegetable protein (acid- HVP), and mixtures of these. 3-Chloropropane-1,2-diol (3-MCPD) is a heat- produced contaminants formed during the preparation of soy sauce and was found to be a by-product of acid-HVPproduced soy sauce in 1978. 3-MCPD has been reported to be carcinogenic, nephrotoxic, and reproductively toxic in laboratory animal testing and has been registered as a chemosterilant for rodent control. 3-MCPD is classified as a possible carcinogenic compound, and the maximum tolerated limit in food has been established at both national and international levels. …”
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402
3-Chloropropane-1,2-diol (3-MCPD) in soy sauce: A review on the formation, reduction, and detection of this potential carcinogen
Published 2015“…There are 3 types of soy sauce: fermented, acid-hydrolyzed vegetable protein (acid- HVP), and mixtures of these. 3-Chloropropane-1,2-diol (3-MCPD) is a heat-produced contaminants formed during the preparation of soy sauce and was found to be a by-product of acid-HVP produced soy sauce in 1978. 3-MCPD has been reported to be carcinogenic, nephrotoxic, and reproductively toxic in laboratory animal testing and has been registered as a chemosterilant for rodent control. 3-MCPD is classified as a possible carcinogenic compound, and the maximum tolerated limit in food has been established at both national and international levels. …”
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403
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Gene Expression Profiling of Chemically Induced Rat Bladder Tumors
Published 2007-03-01Subjects: Get full text
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406
Arsenic Exposure and Breast Cancer Risk: A Re-Evaluation of the Literature
Published 2020-10-01Subjects: Get full text
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407
Arsenic and cadmium concentrations in legumes and cereals grown in the North Central Province, Sri Lanka and assessment of their health risk
Published 2019-02-01Subjects: Get full text
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408
MULTI-ELEMENTAL ANALYSIS AND POTENTIAL HUMAN HEALTH RISK ASSESSMENT OF SELECTED CANNED FOODS SOLD IN NIGERIA
Published 2023-12-01Subjects: Get full text
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Systems Medicine Design for Triple-Negative Breast Cancer and Non-Triple-Negative Breast Cancer Based on Systems Identification and Carcinogenic Mechanisms
Published 2021-03-01“…Comparing core signaling pathways of TNBC and non-TNBC, essential carcinogenic biomarkers resulting in multiple cellular dysfunctions including cell proliferation, autophagy, immune response, apoptosis, metastasis, angiogenesis, epithelial-mesenchymal transition (EMT), and cell differentiation could be found. …”
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412
Health Risk Assessment of Carcinogenic and Non-carcingenic Substances in Underground Water from the Shuangcun Karst System of Central-Southern Shandong Province
Published 2016-01-01“…Currently the majority of water quality assessment in China is based on comparison parameters of water with those of drinking water standards.However, to what extent the pollutants influence human health is less known.Herein, Shuangcun karst water samples in central-southern Shandong province were chosen to evaluate human health risk.Using the risk assessment model of USEPA, the risk induced by two carcinogenic substances, such as As, Cr(Ⅵ) and seven non-carcinogenic substances(Hg, F, CN-, NO2--N, NH4+-N, NO3--N, phenols) are evaluated.Results show that concentration of NO3--N and NO2--N in samples from several sites exceeds the limiting value of Hygienic Standard for Drinking Water(GB5749-2006).In terms of annual personal health risk caused by gene toxic substances through water drinking, Cr(Ⅵ) shows greater risk than As.In terms of risk caused by non-gene toxic substances, the induced risk has the sequence of NO3--N> F> NO2--N> Hg> CN-> NH4+-N> phenols.Moreover, the hazard of carcinogenic substances is much stronger than that of non-carcinogenic substances.Cr(Ⅵ) is the primary pollutant.For all the sampling sites, total risk values range from 5.0×10-5 to 10.0×10-5 a-1, and the risk level is Ⅳ(fair).It means that underground water in the sampling area is harmful to human health to some extent.Therefore, it is worth more attention when the studied water serves as the drinking water source.…”
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413
Use of Arabidopsis thaliana as a model to understand specific carcinogenic events: Comparison of the molecular machinery associated with cancer-hallmarks in plants and humans
Published 2023-04-01“…From this perspective, model organisms with short generation times and established protocols for genetic manipulation allow the understanding of basic biology principles that might guide carcinogenic onset. The cancer-hallmarks (CHs) approach, a modular perspective for cancer understanding, stands that underlying the variability among different cancer types, critical events support the carcinogenic origin and progression. …”
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Deep sequencing of HPV16 genomes: A new high-throughput tool for exploring the carcinogenicity and natural history of HPV16 infection
Published 2015-12-01“…HPV16 is a uniquely powerful carcinogenic type, causing approximately half of cervical cancer and most other HPV-related cancers. …”
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416
Olive Oil Improves While Trans Fatty Acids Further Aggravate the Hypomethylation of LINE-1 Retrotransposon DNA in an Environmental Carcinogen Model
Published 2022-02-01“…For that, mice were fed with EVOO or TFA and were pretreated with environmental carcinogen 7,12-dimethylbenz[a]anthracene (DMBA)—a harmful substance known to cause L1-RTP DNA hypomethylation. …”
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417
Osteoprotegerin (OPG) Upregulation Activates Breast Stromal Fibroblasts and Enhances Their Pro-Carcinogenic Effects through the STAT3/IL-6 Signaling
Published 2022-10-01“…However, specific OPG knock-down suppressed active CAFs and their paracrine pro-carcinogenic effects. Similar effects were observed when CAF cells were exposed to the pure recombinant OPG (rOPG) protein. …”
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Dietary supplementation of black rice bran to colon carcinogen-induced mice: Examining the development of colorectal cancer by improving environmental colon conditions
Published 2023-08-01“…The research was conducted on three groups consisting of eight Balb/c mice: two groups were fed with carcinogens, and the third group, referred to as the normal group, was supplied with Isotonic NaCl 0.9% intraperitoneally. …”
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420
Work Conditions and Practices in Norwegian Fire Departments From 1950 Until Today: A Survey on Factors Potentially Influencing Carcinogen Exposure
Published 2020-12-01“…Background: Meta-analyses have shown firefighters to be at an increased risk of several cancer types. Occupational carcinogen exposure may explain these increased risks. …”
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