Nitrite-Free Implications on Consumer Acceptance and the Behavior of Pathogens in Cured Pork Loins by Luis Patarata, Filipa Carvalho, Maria João Fraqueza

“…The use of nitrite in meat products has been criticized due to its potential contribution to carcinogenic N-nitroso-compound formation. The present work aimed to evaluate the effect of eliminating nitrite from the manufacturing of cured loins made with wine- and water-based marinades on the color evaluation of consumers and on the behavior of <i>Clostridium sporogenes</i>, <i>Listeria monocytogenes</i>, and <i>Salmonella</i>. …”
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MiR-22 Deficiency Fosters Hepatocellular Carcinoma Development in Fatty Liver by Monika Gjorgjieva, Anne-Sophie Ay, Marta Correia de Sousa, Etienne Delangre, Dobrochna Dolicka, Cyril Sobolewski, Christine Maeder, Margot Fournier, Christine Sempoux, Michelangelo Foti

“…Our study demonstrates that miR-22 acts as a hepatic tumor suppressor in vivo by restraining pro-carcinogenic metabolic deregulations through pleiotropic mechanisms and the overexpression of relevant oncogenes.…”
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Development of gold plasmonic nanoparticles for detection of polydiallyldimethylammonium chloride at Umgeni water treatment plants: An optimised study and case application by Sabelo B. Mthembu, Damilola Caleb Akintayo, Brenda Moodley, Bhekumuzi P. Gumbi

“…However, it is very important that residual poly-(DADMAC) is monitored because it disintegrates into a carcinogenic compound known as N-nitrosodimethylamine (NDMA) during the treatment of drinking water. …”
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RNA-SSNV: A Reliable Somatic Single Nucleotide Variant Identification Framework for Bulk RNA-Seq Data by Qihan Long, Qihan Long, Qihan Long, Yangyang Yuan, Yangyang Yuan, Yangyang Yuan, Miaoxin Li, Miaoxin Li, Miaoxin Li, Miaoxin Li, Miaoxin Li

“…In sum, RNA-SSNV will be a useful approach to accurately call expressed somatic mutations for a more insightful analysis of cancer drive genes and carcinogenic mechanisms.…”
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Building a Human Physiologically Based Pharmacokinetic Model for Aflatoxin B1 to Simulate Interactions with Drugs by Orphélie Lootens, Marthe De Boevre, Jia Ning, Elke Gasthuys, Jan Van Bocxlaer, Sarah De Saeger, An Vermeulen

“…The simulations revealed that CYP3A4/CYP1A2 inducer/inhibitor drugs might have an impact on AFB1 metabolism, altering exposure to carcinogenic metabolites. AFB1 did not have effects on the PK of drugs at representative exposure concentrations. …”
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Aerobic Degradation of Trichloroethylene by Co-Metabolism Using Phenol and Gasoline as Growth Substrates by Yan Li, Bing Li, Cui-Ping Wang, Jun-Zhao Fan, Hong-Wen Sun

“…Trichloroethylene (TCE) is a common groundwater contaminant of toxic and carcinogenic concern. Aerobic co-metabolic processes are the predominant pathways for TCE complete degradation. …”
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A Probiotic <i>Bacillus amyloliquefaciens</i> D-1 Strain Is Responsible for Zearalenone Detoxifying in Coix Semen by Tao Deng, Yefei Chen, Jinqiang Zhang, Yanping Gao, Changgui Yang, Weike Jiang, Xiaohong Ou, Yanhong Wang, Lanping Guo, Tao Zhou, Qing-Song Yuan

“…ZEN severely affects food/feed safety and reduces economic losses owing to its carcinogenicity, genotoxicity, reproductive toxicity, endocrine effects, and immunotoxicity. …”
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Investigation and Comparison of Biosorbents for the Removal of the Heavy Metals )Cadmium, Chromium and Lead( from Industrial Wastewater by Hamide Rashidi, Forouzan Farrokhian, Somayeh Zallaghi, Meraj Amirjani

“…Most of them are dangerous to humans and the environment due to their toxicity and carcinogenicity. Some of them, such as cadmium, lead, and chromium in low concentrations, also have toxic effects. …”
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Biomass-Based Cellulose Functionalized by Phosphonic Acid with High Selectivity and Capacity for Capturing U(VI) in Aqueous Solution by Zhipeng Huo, Sheng Zhao, Jinxin Yi, Hong Zhang, Jiaxing Li

“…Uranium could be released into the aquatic ecological environment through various sorts of nuclear-related procedures, which has high toxicity and carcinogenicity even with a trace amount. A novel phosphonic acid functionalized cellulose adsorbent (PVKAP) with a simple synthesis strategy is developed based on pumpkin vine cellulose (PVK) as the substrate material for efficient and selective capturing U(VI). …”
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Reduced Lipid Peroxidation Predicts Unfavorable Prognosis in Hepatocellular Carcinoma, but Not Intrahepatic Cholangiocarcinoma by Tiemo Sven Gerber, Hagen Roland Witzel, Arndt Weinmann, Fabian Bartsch, Mario Schindeldecker, Peter R. Galle, Hauke Lang, Wilfried Roth, Dirk Andreas Ridder, Beate Katharina Straub

“…Oxidative stress and lipid peroxidation play a key role in chronic liver diseases and have been shown to be pivotal for tumor initiation and progression. 4-hydroxy-nonenal (4-HNE), one of the major mediators of oxidative stress and a well-established biomarker for lipid peroxidation, can act as a signal transducer, inducing inflammation and exerting carcinogenic effects. However, the role of 4-HNE in primary liver cancer remains poorly explored. …”
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Familial Risks and Proportions Describing Population Landscape of Familial Cancer by Kari Hemminki, Kristina Sundquist, Jan Sundquist, Asta Försti, Akseli Hemminki, Xinjun Li

“…For the major proportion of familial clustering, where genetic testing may not be feasible, medical and behavioral intervention should be indicated for the patient and their family members, including screening recommendations and avoidance of carcinogenic exposure.…”
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Biochemical composition of a smokeless tobacco product (NASWAR) used in Pakistan by Muhammad Saeed, Muhammad Asad, Muhammad Shahzad, Muhammad Akram, Zohaib Khan

“…Conclusions: Overall, naswar contains an array of organic, inorganic, toxic, and heavy metals and aflatoxin constituents with proven toxic and carcinogenic potential. Furthermore, high pH and nicotine contents make it highly addictive. …”
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Effects of COVID-19 Control Measures on the Concentration and Composition of PM_2.5-Bound Polycyclic Aromatic Hydrocarbons in Shanghai by Jialiang Feng, Fan Fan, Yi Feng, Ming Hu, Jia Chen, Yutong Shen, Qingyan Fu, Shunyao Wang

“…During the lockdown period, the toxic equivalent concentration of PM_2.5-bound PAHs in Shanghai was estimated to decrease by about 1/4, which still exhibits substantial carcinogenic risk upon exposure via inhalation.…”
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Genetic Susceptibility in Head and Neck Squamous Cell Carcinoma in a Spanish Population by Javier Fernández-Mateos, Raquel Seijas-Tamayo, Juan Carlos Adansa Klain, Miguel Pastor Borgoñón, Elisabeth Pérez-Ruiz, Ricard Mesía, Elvira del Barco, Carmen Salvador Coloma, Antonio Rueda Dominguez, Javier Caballero Daroqui, Encarnación Fernández Ruiz, Alberto Ocana, Rogelio González-Sarmiento, Juan Jesús Cruz-Hernández

“…A total of 296 human papillomavirus negative head and neck cancer (HNC) patients (126 laryngeal, 100 pharyngeal and 70 oral cavity) were included in the study, involving 29 candidate SNPs in genes within important carcinogenic pathways (oncogenesis and tumour suppression, DNA repair, inflammation, oxidation and apoptosis). …”
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Chemopreventive Role of Apigenin against the Synergistic Carcinogenesis of Human Papillomavirus and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone by Fangzheng Yin, Lijiao Zhao, Lili Zhang, Yuhe Chen, Guohui Sun, Jintao Li, Na Zhang, Yuancong Xu, Paul Kay-Sheung Chan, Rugang Zhong

“…Apigenin (AP), a typical flavonoid abundantly found in flowers of plants, vegetables, and fruits, has been demonstrated to exert an anti-carcinogenic effect on various types of cancer. In this study, we investigated the capability of AP against malignant transformation and DNA damage of immortalized human esophageal epithelial (SHEE) cells induced by the synergism of HPV18 and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). …”
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Reducing Competition of Pepsin in Aflatoxin Adsorption by Modifying a Smectite with Organic Nutrients by Ana Luisa Barrientos Velazquez, Youjun Deng

“…Carcinogenic aflatoxins can be inactivated by smectites (e.g., montmorillonite) through adsorption and degradation. …”
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Assessing the Risk of Exposure to Aflatoxin B1 through the Consumption of Peanuts among Children Aged 6–59 Months in the Lusaka District, Zambia by Grace Musawa, Flavien Nsoni Bumbangi, Chisoni Mumba, Branly Kilola Mbunga, Gladys Phiri, Vistorina Benhard, Henson Kainga, Mkuzi Banda, Enock Ndaki, Ethel Mkandawire, John Bwalya Muma

“…They constitute a public health concern due to their genotoxic and carcinogenic effects. A deterministic exposure risk assessment to AFB1 through the consumption of peanuts was conducted on children using the Margin of Exposure (MOE) and the liver cancer risk approaches. …”
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Acquired Evolution of Mitochondrial Metabolism Regulated by HNF1B in Ovarian Clear Cell Carcinoma by Ken Yamaguchi, Sachiko Kitamura, Yoko Furutake, Ryusuke Murakami, Koji Yamanoi, Mana Taki, Masayo Ukita, Junzo Hamanishi, Masaki Mandai

“…Because mitochondrial function is suppressed in ovarian CCC, these cancer cells probably acquired further metabolic evolution during the carcinogenic process in order to survive stressful environments.…”
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An Overview of the Role of MicroRNAs on Carcinogenesis: A Focus on Cell Cycle, Angiogenesis and Metastasis by Leonel Pekarek, Diego Torres-Carranza, Oscar Fraile-Martinez, Cielo García-Montero, Tatiana Pekarek, Miguel A. Saez, Francisco Rueda-Correa, Carolina Pimentel-Martinez, Luis G. Guijarro, Raul Diaz-Pedrero, Melchor Alvarez-Mon, Miguel A. Ortega

“…Previous works have cited microRNAs as having a critical role in several carcinogenic mechanisms, ranging from cell cycle alterations to angiogenesis and mechanisms of distant metastatic dissemination. …”
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Groundwater Hydrogeochemical Processes and Potential Threats to Human Health in Fengfeng Coal Mining Area, China by Zhiqiang Zhang, Haixue Li, Fawang Zhang, Jiazhong Qian, Shuangbao Han, Fenggang Dai

“…The quality of the SPW was significantly worse than that of the DKW, and the nitrates in SPW carry a high non-carcinogenic risk, especially to children. The shallow pore water is not suitable for drinking water. …”
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