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4901
Nitrite-Free Implications on Consumer Acceptance and the Behavior of Pathogens in Cured Pork Loins
Published 2022-03-01“…The use of nitrite in meat products has been criticized due to its potential contribution to carcinogenic N-nitroso-compound formation. The present work aimed to evaluate the effect of eliminating nitrite from the manufacturing of cured loins made with wine- and water-based marinades on the color evaluation of consumers and on the behavior of <i>Clostridium sporogenes</i>, <i>Listeria monocytogenes</i>, and <i>Salmonella</i>. …”
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4902
MiR-22 Deficiency Fosters Hepatocellular Carcinoma Development in Fatty Liver
Published 2022-09-01“…Our study demonstrates that miR-22 acts as a hepatic tumor suppressor in vivo by restraining pro-carcinogenic metabolic deregulations through pleiotropic mechanisms and the overexpression of relevant oncogenes.…”
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4903
Development of gold plasmonic nanoparticles for detection of polydiallyldimethylammonium chloride at Umgeni water treatment plants: An optimised study and case application
Published 2023-06-01“…However, it is very important that residual poly-(DADMAC) is monitored because it disintegrates into a carcinogenic compound known as N-nitrosodimethylamine (NDMA) during the treatment of drinking water. …”
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4904
RNA-SSNV: A Reliable Somatic Single Nucleotide Variant Identification Framework for Bulk RNA-Seq Data
Published 2022-06-01“…In sum, RNA-SSNV will be a useful approach to accurately call expressed somatic mutations for a more insightful analysis of cancer drive genes and carcinogenic mechanisms.…”
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4905
Building a Human Physiologically Based Pharmacokinetic Model for Aflatoxin B1 to Simulate Interactions with Drugs
Published 2023-03-01“…The simulations revealed that CYP3A4/CYP1A2 inducer/inhibitor drugs might have an impact on AFB1 metabolism, altering exposure to carcinogenic metabolites. AFB1 did not have effects on the PK of drugs at representative exposure concentrations. …”
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4906
Aerobic Degradation of Trichloroethylene by Co-Metabolism Using Phenol and Gasoline as Growth Substrates
Published 2014-05-01“…Trichloroethylene (TCE) is a common groundwater contaminant of toxic and carcinogenic concern. Aerobic co-metabolic processes are the predominant pathways for TCE complete degradation. …”
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4907
A Probiotic <i>Bacillus amyloliquefaciens</i> D-1 Strain Is Responsible for Zearalenone Detoxifying in Coix Semen
Published 2023-11-01“…ZEN severely affects food/feed safety and reduces economic losses owing to its carcinogenicity, genotoxicity, reproductive toxicity, endocrine effects, and immunotoxicity. …”
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4908
Investigation and Comparison of Biosorbents for the Removal of the Heavy Metals )Cadmium, Chromium and Lead( from Industrial Wastewater
Published 2021-06-01“…Most of them are dangerous to humans and the environment due to their toxicity and carcinogenicity. Some of them, such as cadmium, lead, and chromium in low concentrations, also have toxic effects. …”
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4909
Biomass-Based Cellulose Functionalized by Phosphonic Acid with High Selectivity and Capacity for Capturing U(VI) in Aqueous Solution
Published 2020-08-01“…Uranium could be released into the aquatic ecological environment through various sorts of nuclear-related procedures, which has high toxicity and carcinogenicity even with a trace amount. A novel phosphonic acid functionalized cellulose adsorbent (PVKAP) with a simple synthesis strategy is developed based on pumpkin vine cellulose (PVK) as the substrate material for efficient and selective capturing U(VI). …”
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4910
Reduced Lipid Peroxidation Predicts Unfavorable Prognosis in Hepatocellular Carcinoma, but Not Intrahepatic Cholangiocarcinoma
Published 2023-09-01“…Oxidative stress and lipid peroxidation play a key role in chronic liver diseases and have been shown to be pivotal for tumor initiation and progression. 4-hydroxy-nonenal (4-HNE), one of the major mediators of oxidative stress and a well-established biomarker for lipid peroxidation, can act as a signal transducer, inducing inflammation and exerting carcinogenic effects. However, the role of 4-HNE in primary liver cancer remains poorly explored. …”
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4911
Familial Risks and Proportions Describing Population Landscape of Familial Cancer
Published 2021-08-01“…For the major proportion of familial clustering, where genetic testing may not be feasible, medical and behavioral intervention should be indicated for the patient and their family members, including screening recommendations and avoidance of carcinogenic exposure.…”
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4912
Biochemical composition of a smokeless tobacco product (NASWAR) used in Pakistan
Published 2024-05-01“…Conclusions: Overall, naswar contains an array of organic, inorganic, toxic, and heavy metals and aflatoxin constituents with proven toxic and carcinogenic potential. Furthermore, high pH and nicotine contents make it highly addictive. …”
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4913
Effects of COVID-19 Control Measures on the Concentration and Composition of PM<sub>2.5</sub>-Bound Polycyclic Aromatic Hydrocarbons in Shanghai
Published 2023-01-01“…During the lockdown period, the toxic equivalent concentration of PM<sub>2.5</sub>-bound PAHs in Shanghai was estimated to decrease by about 1/4, which still exhibits substantial carcinogenic risk upon exposure via inhalation.…”
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4914
Genetic Susceptibility in Head and Neck Squamous Cell Carcinoma in a Spanish Population
Published 2019-04-01“…A total of 296 human papillomavirus negative head and neck cancer (HNC) patients (126 laryngeal, 100 pharyngeal and 70 oral cavity) were included in the study, involving 29 candidate SNPs in genes within important carcinogenic pathways (oncogenesis and tumour suppression, DNA repair, inflammation, oxidation and apoptosis). …”
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4915
Chemopreventive Role of Apigenin against the Synergistic Carcinogenesis of Human Papillomavirus and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone
Published 2020-11-01“…Apigenin (AP), a typical flavonoid abundantly found in flowers of plants, vegetables, and fruits, has been demonstrated to exert an anti-carcinogenic effect on various types of cancer. In this study, we investigated the capability of AP against malignant transformation and DNA damage of immortalized human esophageal epithelial (SHEE) cells induced by the synergism of HPV18 and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). …”
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4916
Reducing Competition of Pepsin in Aflatoxin Adsorption by Modifying a Smectite with Organic Nutrients
Published 2020-01-01“…Carcinogenic aflatoxins can be inactivated by smectites (e.g., montmorillonite) through adsorption and degradation. …”
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4917
Assessing the Risk of Exposure to Aflatoxin B1 through the Consumption of Peanuts among Children Aged 6–59 Months in the Lusaka District, Zambia
Published 2024-01-01“…They constitute a public health concern due to their genotoxic and carcinogenic effects. A deterministic exposure risk assessment to AFB1 through the consumption of peanuts was conducted on children using the Margin of Exposure (MOE) and the liver cancer risk approaches. …”
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4918
Acquired Evolution of Mitochondrial Metabolism Regulated by HNF1B in Ovarian Clear Cell Carcinoma
Published 2021-05-01“…Because mitochondrial function is suppressed in ovarian CCC, these cancer cells probably acquired further metabolic evolution during the carcinogenic process in order to survive stressful environments.…”
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4919
An Overview of the Role of MicroRNAs on Carcinogenesis: A Focus on Cell Cycle, Angiogenesis and Metastasis
Published 2023-04-01“…Previous works have cited microRNAs as having a critical role in several carcinogenic mechanisms, ranging from cell cycle alterations to angiogenesis and mechanisms of distant metastatic dissemination. …”
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4920
Groundwater Hydrogeochemical Processes and Potential Threats to Human Health in Fengfeng Coal Mining Area, China
Published 2023-11-01“…The quality of the SPW was significantly worse than that of the DKW, and the nitrates in SPW carry a high non-carcinogenic risk, especially to children. The shallow pore water is not suitable for drinking water. …”
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