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5001
Thyroid-Gut-Axis: How Does the Microbiota Influence Thyroid Function?
Published 2020-06-01“…Dysbiosis has not only been found in AITDs, but has also been reported in thyroid carcinoma, in which an increased number of carcinogenic and inflammatory bacterial strains were observed. …”
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5002
Investigation of heavy metals in selected local spices consumed in Ethiopia
Published 2021-01-01“…In this work, Nigella sativa, Ocimum basilicun, and Ruta chalepensis are good sources of Zn, Cu, Fe, and the number of toxic metals Cd and Pb are below the permissible limit as compared to the value reported in WHO. Therefore, a non-carcinogenic health risk to the consumer associated with the consumption of this spices preparation marketed in study areas.…”
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5003
An AI-driven Predictive Model for Pancreatic Cancer Patients Using Extreme Gradient Boosting
Published 2023-09-01“…Abstract Pancreatic cancer is one of the deadliest carcinogenic diseases affecting people all over the world. …”
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5004
Prognostic and diagnostic value of circRNA expression in prostate cancer: A systematic review and meta-analysis
Published 2022-11-01“…For diagnostic value, the pooled sensitivity, pooled specificity, PLR, NLR, DOR, and AUC were 0.82, 0.62, 2.17, 0.29, 7.37, and 0.81, respectively. Upregulation of carcinogenic circRNAs was associated with poor clinical parameters (Gleason score: OR = 0.222, 95% CI: 0.145–0.340; T classification: OR = 0.274, 95% CI: 0.175–0.430; lymph node metastasis: OR = 0.353, 95% CI: 0.175–0.716; tumor size: OR = 0.226, 95% CI: 0.099–0.518) and could predict poor survival outcomes (HR = 2.408, 95% CI: 1.559–3.720, p < 0.001). …”
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5005
Latifolin, a Natural Flavonoid, Isolated from the Heartwood of <i>Dalbergia odorifera</i> Induces Bioactivities through Apoptosis, Autophagy, and Necroptosis in Human Oral Squamous...
Published 2022-11-01“…Chen (<i>D. odorifera</i>) has been known to have beneficial effects on anti-aging, anti-carcinogenic, anti-inflammatory, and cardio-protective activities. …”
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5006
Evidence for novel polycyclic aromatic hydrocarbon degradation pathways in culturable marine isolates
Published 2024-01-01“…ABSTRACT Polycyclic aromatic hydrocarbons (PAHs) are common toxic and carcinogenic pollutants in marine ecosystems. Despite their prevalence in these habitats, relatively little is known about the natural microflora and biochemical pathways that contribute to their degradation. …”
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5007
Environmental Pollution and Risk of Childhood Cancer: A Scoping Review of Evidence from the Last Decade
Published 2024-03-01“…The long-term effects of environmental pollution have been of concern as several pollutants are carcinogenic, potentially inducing a variety of cancers, including childhood cancer, which is a leading cause of death around the world and, thus, is a public health issue. …”
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5008
Scientific evidence invalidates health assumptions underlying the FCC and ICNIRP exposure limit determinations for radiofrequency radiation: implications for 5G
Published 2022-10-01“…Adverse effects observed at exposures below the assumed threshold SAR include non-thermal induction of reactive oxygen species, DNA damage, cardiomyopathy, carcinogenicity, sperm damage, and neurological effects, including electromagnetic hypersensitivity. …”
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5009
EFFECT BY INTESTINAL MICROBIOM ON THE PROGRESSION OF VIRAL HEPATITIS
Published 2017-01-01“…These toxins formation and various carcinogenic metabolites from these strains leads to the inflammation development in the intestines and as a consequence to the progression of the inflammatory process in the liver. …”
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5010
The Efficient and Easy Micropropagation Protocol of <i>Phyllanthus niruri</i>
Published 2021-10-01“…<i>P. niruri </i>contains numerous medicinal benefits such as anti-tumor and anti-carcinogenic properties and a remedy for hepatitis B viral infection. …”
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5011
Human Health Risk Assessment of Heavy Metals in the Urban Road Dust of Zhengzhou Metropolis, China
Published 2021-09-01“…The results identified non-carcinogenic exposure of children to lead (HI > 0.1) in commercial and industrial areas. …”
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5012
Design, Synthesis of New 1,2,4-Triazole/1,3,4-Thiadiazole with Spiroindoline, Imidazo[4,5-b]quinoxaline and Thieno[2,3-d]pyrimidine from Isatin Derivatives as Anticancer Agents
Published 2022-01-01“…The derivatives 3-((bromophenyl) imino)-1-(morpholino (pyridine) methyl) indolin-2-one, 2-((oxoindoline) amino) benzoic acid, 3-(thiazolo-imino) indolinone, ethyl-2-((oxoindolin-3-ylidene)amino)-benzothiophene-3-carboxylate, 1-(oxoindoline)-benzo[4,5] thieno [2,3-d]pyrimidin-4(1H)-one, ethyl-2-(2-oxoindoline) hydrazine-1-carboxylate, N-(mercapto-oxo-pyrimidine)-2-(oxoindoline) hydrazine-1-carboxamide, N-(oxo-thiazolo[3,2-a] pyrimidine)-2-(oxoindolin-ylidene) hydrazine-carboxamide, 3-((amino-phenyl) amino)-3-hydroxy- indolinone, 3-((amino-phenyl) imino)-indolinone, 2-(2-((oxoindoline) amino) phenyl) isoindolinone, 2-(oxoindoline) hydrazine-carbothioamide, 5′-thioxospiro[indoline-3,3′-[1,2,4]triazolidin]-one, 5′-amino-spiro[indoline-3,2′-[1,3,4]thiadiazol]-2-one and 3-((2-thioxo-imidazo[4,5-b]quinoxaline) imino) indolinone were synthesized from the starting material 1-(morpholino (pyridine) methyl) indoline-2,3-dione and evaluated for their in vitro cytotoxic activity against carcinogenic cells. The new chemical structures were evidenced using spectroscopy (IR, NMR and MS) and elemental analysis. …”
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5013
Atrazine degradation by Bacillus safensis strain BUK_BCH_BTE6 isolated from agricultural land in northwestern Nigeria
Published 2023-09-01“…Atrazine herbicide is known to disrupt the endocrine system and is potentially carcinogenic. Its continual application leads to high residue levels in soil, causing water pollution, which when consumed is associated with devastating health effects. …”
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5014
The Contamination of “Gaz” to Aflatoxin Residue in Isfahan City, Iran
Published 2016-02-01“…Background: Aflatoxins are toxic and carcinogenic secondary metabolites usually produced by certain strains of the fungi such as Aspergillus flavus, Aspergillus parasiticus and rarely Aspergillus nomius. …”
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5015
Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolit...
Published 2023-08-01“…These simulations of reduction in GSH are also consistent with the gene expression results showing the most sensitive pathways are Nrf2-regulation of oxidative stress and GSH metabolism.Discussion: The PBPK model is used to correlate predicted tissue exposure to reactive metabolites with toxicity and carcinogenicity of CP.…”
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5016
Identification and prioritisation for risk assessment of phthalates, structurally similar substances and replacement substances potentially used as plasticisers in materials and ar...
Published 2022-05-01“…Five substances classified either as carcinogenic, mutagenic, toxic to reproduction Cat. 1 (under CLP) or as endocrine disruptors, persistent, bioaccumulative and toxic, very persistent/very bioaccumulative (under REACH) were placed into an ‘exclusion group’. …”
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5017
Impact of Polycyclic Aromatic Hydrocarbons (PAHs) from an Asphalt Mix Plant in a Suburban Residential Area
Published 2020-07-01“…Polycyclic aromatic hydrocarbons (PAHs), an important class of hazardous airborne pollutants, are mutagenic and carcinogenic substances known to be released during the paving of asphalt. …”
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5018
Effects of high and low dose of cadmium chloride on male Reproductive system in mice
Published 2012-04-01“…Background: Cadmium is highly toxic and carcinogenic environmental contaminant exposure to cadmium has been reported to reduce male fertility and there are several hypotheses that suggest how reduced male fertility may result from incorporation of cadmium. …”
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5019
Distribution and sources of polycyclic aromatic hydrocarbons in soils along the Shatt Al-Arab River Delta in southern Iraq
Published 2019-06-01“…The total toxic equivalent concentrations (Bapteq) of PAHs in the examined areas did not exceed the Dutch target values suggesting that no carcinogenic risk for the SR delta soils was found.…”
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5020
Concentration and Human Health Risk Assessment of Alkylphenols, Bisphenols and Some Heavy Metals in Selected Canned Foods in Lagos, Nigeria
Published 2023-03-01“…The results from the hazard index (HI) suggest that there is a risk of a non-carcinogenic toxic effect for canned tomatoes, canned fish, canned corn, canned beans, and canned peas as their values were greater than 1. …”
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