Investigation into the Potential Role of <i>Propionibacterium freudenreichii</i> in Prevention of Colorectal Cancer and Its Effects on the Diversity of Gut Microbiota in Rats by Ifeoma Julieth Dikeocha, Abdelkodose Mohammed Al-Kabsi, Ahmad Faheem Ahmeda, Michael Mathai, Mohammed Abdullah Alshawsh

“…In conclusion, these results reveal that consuming PF as probiotic supplements modulates gut microbiota, inhibits the carcinogenic effects of AOM, and exerts anti-proliferative activity against CRC cells. …”
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Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue by Liu Suling, Huang Yi-Wen, Wang Li-Shu, Yan Pearlly, Lin Young C

“…Furthermore, treatment with 17β-estradiol (E₂) stimulated growth and up-regulated Bcl-2 expression in estrogen responsive breast epithelial cells; however, these carcinogenic effects were diminished by either CLA or 4-Hydroxytamoxifen (Tam) and were suppressed further by the combination of CLA and Tam. …”
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Bibliometric evaluation of nanoadsorbents for wastewater treatment and way forward in nanotechnology for clean water sustainability by Kayode Adesina Adegoke, Solomon Olanrewaju Giwa, Oyeladun Rhoda Adegoke, Nobanathi Wendy Maxakato

“…Research hotspots in the nanoadsorbents for wastewater treatment were summed up as application of nanoadsorbent to decontaminate different carcinogenic, mutagenic, and toxic compounds discharged from various processes. …”
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NATO attack on FR Yugoslavia in 1999 was used to test the effectiveness of new weapons by Mirjana N. Anđelković-Lukić, Ljubica M. Radović

“…A semi-quantitative analysis of the fibers was performed on the SEM, confirming that the metal layer of the fiber predominantly consists of aluminum, and the non-metallic layer has the highest proportion of silicon dioxide. The fiber is carcinogenic. Conclusion: In 1999, the territory of Yugoslavia was a testing ground for new combat weapons of NATO aviation - B-2 and JDAM guided bombs. …”
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Probiotics intervention in colorectal cancer: From traditional approaches to novel strategies by Suki Ha, Xiang Zhang, Jun Yu, Yuanyuan Ji

“…The underlying mechanisms of probiotic anti-cancer effects are also discussed, including the restoration of microbial composition, reinforcement of gut barrier integrity, induction of cancer cell apoptosis, inactivation of carcinogens, and modulation of host immune response. …”
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Synthesis of activated carbon from cherry tree waste and its application in removing cationic red 14 dye from aqueous environments by Roya Askari, Faezeh Mohammadi, Amir Moharrami, Shirin Afshin, Yousef Rashtbari, Mehdi Vosoughi, Abdollah Dargahi

“…The characteristics detected for the dye, e.g., toxicity and carcinogenicity, have brought severe problems for humans and aquatic organisms. …”
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Availability and accuracy of occupation in cancer registry data among Florida firefighters. by Laura A McClure, Tulay Koru-Sengul, Monique N Hernandez, Jill A Mackinnon, Natasha Schaefer Solle, Alberto J Caban-Martinez, David J Lee, David J Lee, Erin Kobetz

“…<h4>Objectives</h4>Occupational exposures significantly contribute to the risk of adverse cancer outcomes, and firefighters face many carcinogenic exposures. Occupational research using cancer registry data, however, is limited by missing and inaccurate occupation-related fields. …”
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Risk Assessment of Heavy Metals in Sediment Samples from the Mae Chaem River, Chiang Mai, Thailand by Sawaeng Kawichai, Tippawan Prapamontol, Teetawat Santijitpakdee, Susira Bootdee

“…The hazard quotient (HQ) was used to estimate the non-carcinogenic risk of exposure to heavy-metal-bound surface sediments for both children and adults. …”
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Variation in Occurrence and Aflatoxigenicity of <i>Aspergillus flavus</i> from Two Climatically Varied Regions in Kenya by Ethel Monda, Joel Masanga, Amos Alakonya

“…Aflatoxins are carcinogenic chemical metabolites produced by <i>Aspergillus</i> spp. of the section <i>Flavi.…”
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Occurrences, sources and health hazard estimation of potentially toxic elements in the groundwater of Garhwal Himalaya, India by R. S. Aswal, Mukesh Prasad, Narendra K. Patel, A. L. Srivastav, Johnbosco C. Egbueri, G. Anil Kumar, R. C. Ramola

“…Estimated water pollution indices and non-carcinogenic risk indicated that the investigated groundwater is safe for drinking purpose, as the hazard index was < 1 for all the water samples. …”
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Major radiodiagnostic imaging in pregnancy and the risk of childhood malignancy: a population-based cohort study in Ontario. by Joel G Ray, Michael J Schull, Marcelo L Urquia, John J You, Astrid Guttmann, Marian J Vermeulen

“…Since the upper confidence limit of the relative risk of malignancy may be as high as 1.8 times that of an unexposed pregnancy, we cannot exclude the possibility that fetal exposure to CT or radionuclide imaging is carcinogenic.…”
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High fat diet and exercise lead to a disrupted and pathogenic DNA methylome in mouse liver by Dan Zhou, Ryan A. Hlady, Marissa J. Schafer, Thomas A. White, Chen Liu, Jeong-Hyeon Choi, Jordan D. Miller, Lewis R. Roberts, Nathan K. LeBrasseur, Keith D. Robertson

“…Hypermethylation at a subset of gene promoters was associated with inhibition of tissue development and promotion of carcinogenic processes. Our study demonstrates extensive reprogramming of the epigenome by diet and exercise, emphasizing the functional relevance of epigenetic mechanisms as an interface between lifestyle modifications and phenotypic alterations.…”
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Bioefficacy of Nga-Mon (<i>Perilla frutescens</i>) Fresh and Dry Leaf: Assessment of Antioxidant, Antimutagenicity, and Anti-Inflammatory Potential by Payungsak Tantipaiboonwong, Komsak Pintha, Wittaya Chaiwangyen, Maitree Suttajit, Chakkrit Khanaree, Orawan Khantamat

“…Furthermore, both extracts were found to suppress intracellular ROS generation and exhibit antimutagenic activity against food-borne carcinogens in <i>S. typhimurium</i>. They also attenuated lipopolysaccharide-induced inflammation in RAW 264.7 cells by inhibiting the expression of nitric oxide, iNOS, COX-2, TNF-α, IL-1β, and IL-6 through the suppression of NF-κB activation and translocation. …”
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Inhibition of cytosine 5-hydroxymethylation during progression of cancer precursor lesions in the uterine cervix. by Jobran M Moshi, Monique Ummelen, Frank Smedts, Frans C S Ramaekers, Anton H N Hopman

“…We studied global (hydroxy)methylation during the subsequent steps in the carcinogenic process of the uterine cervix by using immunohistochemical protocols for the detection of 5-methylcytosine (5-mC) and 5-hydroxymethylcytosine (5-hmC) in paraffin-embedded tissues of the normal epithelia and (pre)malignant lesions. …”
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Expression and shedding of endothelial protein C receptor in prostate cancer cells by Eisenhofer Graeme, Klinsmann Ludwig, Tiebel Oliver, Hagelgans Albert, Menschikowski Mario, Siegert Gabriele

“…<p>Abstract</p> <p>Background</p> <p>Increasing evidences show that beyond its role in coagulation, endothelial protein C receptor (EPCR) interferes with carcinogenesis. Pro-carcinogenic effects of EPCR were linked with a raised generation of activated protein C (aPC) and anti-apoptotic signalling. …”
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Risk assessment of N‐nitrosamines in food by EFSA Panel on Contaminants in the Food Chain (EFSA CONTAM Panel), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús delMazo, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Benigni Romualdo, Cristina Fortes, Stephen Hecht, Marco Iammarino, Olaf Mosbach‐Schulz, Francesca Riolo, Anna Christodoulidou, Bettina Grasl‐Kraupp

“…The risk assessment was confined to those 10 carcinogenic N‐NAs occurring in food (TCNAs), i.e. NDMA, NMEA, NDEA, NDPA, NDBA, NMA, NSAR, NMOR, NPIP and NPYR. …”
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A Single nucleotide polymorphism in the ALDH2 gene modifies the risk of esophageal squamous cell carcinoma in BRCA2 p.K3326* carriers. by Neda Zamani, Agata Szymiczek, Ramin Shakeri, Hossein Poustchi, Akram Pourshams, Steven Narod, Reza Malekzadeh, Mohammad R Akbari

“…Recently, it has been reported that aldehydes can induce BRCA2 haploinsufficiency in cells with a heterozygous pathogenic BRCA2 mutation and predispose them to carcinogenic effects. Based on this observation, we speculate that dysfunctional variants in Aldehyde Dehydrogenase 2 Family Member (ALDH2) may result in aldehyde-induced BRCA2 haploinsufficiency and increase cancer risk in BRCA2 mutation carriers. …”
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Nitrates/Nitrites in Food—Risk for Nitrosative Stress and Benefits by Małgorzata Karwowska, Anna Kononiuk

“…This is because, for years, the cancer risks of nitrates/nitrites have been considered, since they potentially convert into the nitrosamines that have carcinogenic effects. This has resulted in the development and rapid expansion of meat products processed with plant-derived nitrates as nitrite alternatives in meat products. …”
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Effect of Nanosilica and Bentonite as Mycotoxins Adsorbent Agent in Broiler Chickens’ Diet on Growth Performance and Hepatic Histopathology by Abdallah A. Ghazalah, Mamduh O. Abd-Elsamee, Kout Elkloub M. E. Moustafa, Mohamed Abdelrazik Khattab, Abd-Elrahim A. A. Rehan

“…Mycotoxins can cause many serious complications to both humans and animals due to carcinogenic, mutagenic, and immunosuppressive disorders. …”
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Tumor‐derived endomucin promotes colorectal cancer proliferation and metastasis by Qi Huang, Xue‐mei Li, Jing‐ping Sun, Yan Zhou

“…Furthermore, functional annotation analysis indicated that these genes were considerably enriched in carcinogenic‐related functions and pathways. Collectively, the identification of EMCN‐binding partners enhanced our understanding of the mechanism of EMCN‐mediated malignant phenotypes, and this research may provide valuable insights into the molecular mechanisms underlying CRC. …”
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