Association between colorectal cancer and expression levels of miR-21, miR-17-5P, miR-155 genes and the presence of Fusobacterium nucleatum in biopsy samples obtained from Iranian... by Nazila Bostanshirin, Bahareh Hajikhani, Amir Abbas Vaezi, Fatemeh Kermanian, Fatemeh Sameni, Somayeh Yaslianifard, Mehdi Goudarzi, Masoud Dadashi

“…Abstract Background Colorectal cancer (CRC) is considered the second-deadliest and third-most common malignancy worldwide. Studying the carcinogenic mechanism of bacteria or their role in aggravating cancer can be precious. …”
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Understanding and harnessing triple-negative breast cancer-related microbiota in oncology by Ciaran Devoy, Ciaran Devoy, Ciaran Devoy, Yensi Flores Bueso, Yensi Flores Bueso, Yensi Flores Bueso, Mark Tangney, Mark Tangney, Mark Tangney, Mark Tangney

“…It may suppress or promote carcinogenesis through the release of carcinogenic metabolites, sustenance of proinflammatory environments and/or the promotion of epigenetic changes in our genome. …”
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Enhanced biodegradation of phenanthrene and anthracene using a microalgal-bacterial consortium by Mubasher Zahir Hoque, Abdulrahman Alqahtani, Saravanan Sankaran, Deepak Anand, Musa M. Musa, Musa M. Musa, Alexis Nzila, Alexis Nzila, Gea Guerriero, Khawar Sohail Siddiqui, Irshad Ahmad, Irshad Ahmad

“…The bioaccumulation, carcinogenic and mutagenic potential of PAHs necessitates the bioremediation of these contaminants. …”
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Fatty acid metabolism-related genes as a novel module biomarker for kidney renal clear cell carcinoma: Bioinformatics modeling with experimental verification by Zongming Jia, Zhenyu Fu, Ying Kong, Chengyu Wang, Bin Zhou, Yuxin Lin, Yuhua Huang

“…Conclusions: In this study, a novel risk score model and a module biomarker based on FAM-related genes were screened for KIRC prognosis. More clinical carcinogenic validations will be performed for future translational applications of the findings.…”
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Low Doses of PFOA Promote Prostate and Breast Cancer Cells Growth through Different Pathways by Aurélie Charazac, Charlotte Hinault, Bastien Dolfi, Solène Hautier, Célia Decondé Le Butor, Frédéric Bost, Nicolas Chevalier

“…Thus, our study demonstrates that even at picomolar (10⁻¹² M) concentrations PFOA and PCB153 increase the proliferation of prostate and breast cancer cell lines and can be considered possible carcinogens.…”
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p53-dependent HIF-1α /autophagy mediated glycolysis to support Cr(VI)-induced cell growth and cell migration by Yanqiu Yang, Bin Song, Minna Guo, Jianfeng Gao, Liping Jiang, Qiujuan Li, Yong Liu, Jun Cao

“…Cr(VI) is known to be seriously toxic and carcinogenic. Hypoxia-inducible factor-1α (HIF-1α) is a crucial regulator to promote tumor development. …”
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N-Glycomic Profiling of Microsatellite Unstable Colorectal Cancer by Iiris Ukkola, Pirjo Nummela, Annamari Heiskanen, Matilda Holm, Sadia Zafar, Mia Kero, Caj Haglund, Tero Satomaa, Soili Kytölä, Ari Ristimäki

“…Our results show that molecular subgroups of CRC exhibit characteristic glycan profiles that may explain certain carcinogenic properties of MSI tumors.…”
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Insoluble chitosan complex as a potential adsorbent for aflatoxin B1 in poultry feed by Armando Delgado-Cedeño, Sara Paola Hernández-Martínez, Sara Paola Hernández-Martínez, Yareellys Ramos-Zayas, Yareellys Ramos-Zayas, Alicia Guadalupe Marroquín-Cardona, Gerardo Méndez-Zamora, Gerardo Méndez-Zamora, Moisés Armides Franco-Molina, Jorge R. Kawas, Jorge R. Kawas

“…As a class of secondary metabolites or toxins produced by fungi, aflatoxins can poison humans and animals; among them, aflatoxin B1 (AFB1) is the most dangerous one owing to its carcinogenic and mutagenic properties that increase risks for hepatocellular carcinoma in humans; hence, adsorbents such as smectites are commonly included in poultry feed to mitigate their effects. …”
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A Review of Titanium Dioxide (TiO₂)-Based Photocatalyst for Oilfield-Produced Water Treatment by Hadi Nugraha Cipta Dharma, Juhana Jaafar, Nurul Widiastuti, Hideto Matsuyama, Saied Rajabsadeh, Mohd Hafiz Dzarfan Othman, Mukhlis A Rahman, Nurul Natasha Mohammad Jafri, Nuor Sariyan Suhaimin, Atikah Mohd Nasir, Nur Hashimah Alias

“…Oilfield produced water (OPW) has become a primary environmental concern due to the high concentration of dissolved organic pollutants that lead to bioaccumulation with high toxicity, resistance to biodegradation, carcinogenicity, and the inhibition of reproduction, endocrine, and non-endocrine systems in aquatic biota. …”
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Current Developments of Analytical Methodologies for Aflatoxins’ Determination in Food during the Last Decade (2013–2022), with a Particular Focus on Nuts and Nut Products by Andrea Schincaglia, Juan Aspromonte, Flavio A. Franchina, Tatiana Chenet, Luisa Pasti, Alberto Cavazzini, Giorgia Purcaro, Marco Beccaria

“…Indeed, AFs are considered carcinogenic to humans, group 1, by the International Agency for Research on Cancer (IARC). …”
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Identification regulatory noncoding RNAs of human papilloma virus type 16 <i>(Papillomaviridae: Alphapapillomavirus: Human papillomavirus)</i> in cervical tumors by Natalia P. Kisseljova, Maria D. Fedorova, Anastasia E. Zaikina, Nadezhda V. Elkina, Ekaterina E. Goldobina, Danila S. Elkin, Pavel M. Abramov, Larisa S. Pavlova, Svetlana V. Vinokurova

“…Introduction. High carcinogenic-risk human papillomaviruses (hrHPVs) are recognized as etiological agents of cervical cancer. …”
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De Novo Carcinoma after Solid Organ Transplantation to Give Insight into Carcinogenesis in General—A Systematic Review and Meta-Analysis by Eline S. Zwart, Esen Yüksel, Anne Pannekoek, Ralph de Vries, Reina E. Mebius, Geert Kazemier

“…Analysis of the occurrence of different types of de novo carcinomas in relation to specific immunosuppressive drugs may give insight into their carcinogenic process and carcinogenesis in general. Therefore, a systematic search was performed in Embase and PubMed. …”
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Translating the Manufacture of Immunotherapeutic PLGA Nanoparticles from Lab to Industrial Scale: Process Transfer and In Vitro Testing by Maria Camilla Operti, Alexander Bernhardt, Jeanette Pots, Vladimir Sincari, Eliezer Jager, Silko Grimm, Andrea Engel, Anne Benedikt, Martin Hrubý, Ingrid Jolanda M. De Vries, Carl G. Figdor, Oya Tagit

“…The investigated formulations contain three distinct synthetic peptides derived from the carcinogenic antigen New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1) together with an invariant natural killer T-cell (iNKT) activator, threitolceramide-6 (IMM60). …”
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Exploring the Mechanism of Hepatotoxicity Induced by <i>Dictamnus dasycarpus</i> Based on Network Pharmacology, Molecular Docking and Experimental Pharmacology by Peng Gao, Kun Chang, Shuo Yuan, Yanhang Wang, Kewu Zeng, Yong Jiang, Pengfei Tu, Yingyuan Lu, Xiaoyu Guo

“…Our results showed that the targets of DC included CYP1A2 and GSR, participating in heterologous steroid metabolism, REDOX metabolism, drug metabolism, heterocyclic metabolic processes, the synthesis of steroid hormone, cytochrome P450 metabolism, chemical carcinogens and bile secretion pathways. In vitro and in vivo experiments displayed that DC could result in a decrease in GSH-Px and oxidative stress, simultaneously inhibiting the expression of CYP1A2 and inducing hepatotoxicity. …”
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<i>Ascophyllum nodosum</i> (Linnaeus) Le Jolis from Arctic: Its Biochemical Composition, Antiradical Potential, and Human Health Risk by Ekaterina D. Obluchinskaya, Olga N. Pozharitskaya, Elena V. Gorshenina, Anna V. Daurtseva, Elena V. Flisyuk, Yuliya E. Generalova, Inna I. Terninko, Alexander N. Shikov

“…According to the calculated target hazard quotient (THQ) and hazard index (HI) values, Arctic <i>A. nodosum</i> samples pose no carcinogenic risk to adult and child health and are safe for regular consumption. …”
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Characteristics and Health Risk Assessment of PM_2.5-Bound PAHs during Heavy Air Pollution Episodes in Winter in Urban Area of Beijing, China by Mei Luo, Yuanyuan Ji, Yanqin Ren, Fuhong Gao, Hao Zhang, Lihui Zhang, Yanqing Yu, Hong Li

“…PAHs posed obvious carcinogenic risks to the exposed populations, and the risk was higher during heavy pollution episodes than the average value of the whole monitoring period. …”
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Characterization and Kinetic Studies of Poly(vinylidene fluoride-co-hexafluoropropylene) Polymer Inclusion Membrane for the Malachite Green Extraction by Jillin Ai Lam Soo, Muaz Mohd Zaini Makhtar, Noor Fazliani Shoparwe, Tunmise Ayode Otitoju, Mardawani Mohamad, Lian See Tan, Sanxi Li

“…Textile industry effluent contains a high amount of toxic colorants. These dyes are carcinogenic and threats to the environment and living beings. …”
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Scientific opinion on the renewal of the authorisation of SmokEz C‐10 (SF‐005) as a smoke flavouring Primary Product by EFSA Panel name on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Laurence Castle, Gisela Degen, Karl‐Heinz Engel, Paul J Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Ursula Gundert‐Remy, Rainer Gürtler, Trine Husøy, Melania Manco, Peter Moldeus, Sabina Passamonti, Romina Shah, Ine Waalkens‐Berendsen, Matthew Wright, Romualdo Benigni, Polly Boon, Claudia Bolognesi, Eugenia Cordelli, Kevin Chipman, Gisela Degen, Ullrika Sahlin, Maria Carfì, Carla Martino, Salvatore Multari, Vasantha Palaniappan, Alexandra Tard, Wim Mennes

“…Considering that the exposure estimates for these two components are above the threshold of toxicological concern (TTC) of 0.0025 μg/kg bw per day for DNA‐reactive mutagens and/or carcinogens, the Panel concluded that the Primary Product raises concern with respect to genotoxicity.…”
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Corn Flour Intake, Aflatoxin B₁ Exposure, and Risk of Esophageal Precancerous Lesions in a High-Risk Area of Huai’an, China: A Case-Control Study by Shaokang Wang, Da Pan, Ting Zhang, Ming Su, Guiju Sun, Jie Wei, Ziqi Guo, Kai Wang, Guang Song, Qingyang Yan

“…Aflatoxin B₁ (AFB₁), which has potent toxicity and carcinogenicity, is a common contaminant of important agricultural commodities. …”
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Role of the WNT/β-catenin/ZKSCAN3 Pathway in Regulating Chromosomal Instability in Colon Cancer Cell lines and Tissues by Young-Eun Cho, Jeong-Hee Kim, Young-Hyun Che, Yong-Jun Kim, Ji-Youn Sung, Yoon-Wha Kim, Bong-Geun Choe, Sun Lee, Jae-Hoon Park

“…However, most of the ZKSCAN3-induced carcinogenic mechanisms remain unknown. In this study, we identified ZKSCAN3 as a downstream effector of the oncogenic Wnt/β-catenin signaling pathway, using RNA sequencing and ChIP analyses. …”
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