A novel MB-tagged aptasensor for Aflatoxin B1 detection in food using Fe3O4 nanoparticles substantiated with in silico modelling by Lyndon Naidoo, Gloria Ebube Uwaya, Florian Meier, Krishna Bisetty

“…Aspergillus fungi species found in wheat, maize, rice, and other agricultural products produce the carcinogenic mycotoxin known as Aflatoxin B1 (AFB1), which can cause cancer in animals and humans. …”
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Histopathological evaluation of lesions induced by dimethyl hydrazine in male rats by Entisar Kh. Al-Hamdany, Karam H. Al-Mallah, Hana Kh. Ismail

“…This study evaluated dimethylhydrazines' carcinogenic and toxic effect (DMH) in male rats; 30 albino rats were divided into three groups, randomly ten rates for each one. …”
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Pirfenidone regulates antioxidant response via NRF2 in an experimental model of hepatocellular carcinoma by HC Monroy-Ramírez, HO Miranda-Roblero, M Galicia-Moreno, A Santos-García, J Armendáriz-Borunda

“…Materials and methods: Eighteen Fischer-344 rats divided into three groups were used: 1) untreated (NT), 2) carcinogenic damage (HCC) generated by weekly administration of diethylnitrosamine (50mg/kg/week;i.p.) and 2-Acetylaminofluorene (25mg/ kg/wk, p.o) and 3) HCC treated with PFD (300 mg/kg, p.o.) …”
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Effect of Rs5746136 genotypes on SOD activity and biomarkers levels in breast cancer patients by Hadi Sajid Abdulabbas, Yasir Haider Al-Mawlah

“…Oxidative stress factors are among the most common carcinogens, Superoxide dismutase enzyme-2 (SOD2) is an endogenous antioxidant involved in the scavenging of superoxide anions. …”
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Redistribution of the SWI/SNF Complex Dictates Coordinated Transcriptional Control over Epithelial–Mesenchymal Transition of Normal Breast Cells through TGF-β Signaling by Sham Jdeed, Máté Lengyel, Iván P. Uray

“…However, whether modulating ARID1A function in premalignant breast epithelial cells could be exploited to reduce carcinogenic potential remains to be elucidated. In search of chromatin-modulating mechanisms activated by anti-proliferative agents in normal breast epithelial (HME-hTert) cells, we identified a distinct pattern of genome-wide H3K27 histone acetylation marks characteristic for the combined treatment by the cancer preventive rexinoid bexarotene (Bex) and carvedilol (Carv). …”
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Source apportionment and source-specific risk evaluation of potential toxic elements in oasis agricultural soils of Tarim River Basin by Yizhen Li, Jilili Abuduwaili, Long Ma, Wen Liu, Tao Zeng

“…The PTEs in the Hotan Oasis corresponded to a moderate level of risk to the ecological environment, and the noncarcinogenic risk of soil PTEs in the four oases to local children exceeded the threshold (TH > 1), while the carcinogenic risk to local residents was acceptable (1E−06 < TCR < 1E−04). …”
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Heavy metal concentration from gas flaring sites in Umuebulu Etche l.g.a and Agbada II in ObioAkpor/Ikwere l.g.a, Rivers State, Nigeria by Sordum Baridakara, Rachel Enemuguem, Barisi Samuel-Felix, Barisi Samuel-Penu

“…Heavy metal contamination is of great concern due to its effect as being carcinogenic in nature. Heavy metal concentration was determined in bitter leaf, plantain leaf, cassava leaf, cassava tuber, pepper leaf, pepper fruit, pawpaw leaf, pawpaw fruit, water leaf around gas flaring sites in Umuebulu Etche LGA and Agbada II in Obio/Akpor LGA Rivers State. …”
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Determination of Aflatoxin B₁ in Grains by Aptamer Affinity Column Enrichment and Purification Coupled with High Performance Liquid Chromatography Detection by Cong Ji, Xinyang Sun, Yong Fang, Peng Li

“…Aflatoxin B₁ (AFB₁) is a highly teratogenic and carcinogenic secondary metabolite produced by <i>Aspergillus</i>. …”
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Cell Membrane-Camouflaged Nanoparticles Mediated Nucleic Acids Delivery by Lin Y, Guan X, Su J, Chen S, Fu X, Xu X, Deng X, Chang J, Qin A, Shen A, Zhang L

“…Although viral vectors have shown high transfection efficiency, concerns regarding teratogenicity or carcinogenicity have been raised. Non-viral vehicles, including cationic polymers, liposomes, and inorganic materials possess advantages in terms of safety, ease of preparation, and low cost. …”
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Development of a method to assess the risk of aflatoxin contamination of corn within counties in southern Georgia, USA using remotely sensed data by R. Kerry, B. Ingram, M. Orellana, B.V. Ortiz, B. Scully

“…Aflatoxins (AFs) are carcinogenic toxins produced by fungi in many staple grain crops. …”
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Polychlorinated biphenyls in residential soils and their health risk and hazard in an industrial city in India by Bhupander Kumar, Virendra Kumar Verma, Satish Kumar Singh, Sanjay Kumar, Chandra Shekhar Sharma, Avinash B. Akolkar

“…Their close proximity may also lead to human exposure through ingestion, inhalation, dermal contact, and may exert neurotoxic, mutagenic and carcinogenic health effects. <br /><em>Design and Methods</em>. …”
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Dipeptidyl peptidase-4 inhibitors and the risk of skin cancer among patients with type 2 diabetes: a UK population-based cohort study by Robert W Platt, Laurent Azoulay, Oriana H Y Yu, Richeek Pradhan

“…Introduction The dipeptidyl peptidase-4 (DPP-4) enzyme significantly influences carcinogenic pathways in the skin. The objective of this study was to determine whether DPP-4 inhibitors are associated with the incidence of melanoma and nonmelanoma skin cancer, compared with sulfonylureas.Research design and methods Using the United Kingdom Clinical Practice Research Datalink, we assembled two new-user active comparator cohorts for each skin cancer outcome from 2007 to 2019. …”
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Anthropogenic hyperactivity for natural resources increases heavy metals concentrations in the environment: Toxicity of healthy food and cancer risks estimated by David Johane Machate

“…This review highlights high concentration of heavy metals and metalloids in principal food daily intake and nutritionally accepted as healthy products, which were correlated with production sites, plus carcinogenic risks calculated and some metabolic diseases associated with reported cancer risk. …”
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Impact and underlying mechanisms of osteoblast-derived exosomes on biological characteristics of prostate cancer cells by LI Jingyi, CHEN Jiajiu, LI Yaoming

“…Conclusion Osteoblast-derived exosomes are pro-carcinogenic factors in PC, and miR-223 may be a key molecule in exosomes, which plays a oncogenic role by regulating APC in PC cells. …”
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Cell Adhesion Molecules Affected by Ionizing Radiation and Estrogen in an Experimental Breast Cancer Model by Gloria M. Calaf, Leodan A. Crispin, Juan P. Muñoz, Francisco Aguayo, Gopeshwar Narayan, Debasish Roy

“…Cancer develops in a multi-step process where environmental carcinogenic exposure is a primary etiological component, and where cell–cell communication governs the biological activities of tissues. …”
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Scientific opinion on the renewal of the authorisation of Scansmoke SEF7525 (SF‐004) as a smoke flavouring Primary Product by EFSA Panel name on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Laurence Castle, Gisela Degen, Karl‐Heinz Engel, Paul J Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Ursula Gundert‐Remy, Rainer Gürtler, Trine Husøy, Melania Manco, Peter Moldeus, Sabina Passamonti, Romina Shah, Ine Waalkens‐Berendsen, Matthew Wright, Romualdo Benigni, Polly Boon, Claudia Bolognesi, Eugenia Cordelli, Kevin Chipman, Ullrika Sahlin, Maria Carfì, Edoardo Carnesecchi, Carla Martino, Agnieszka Mech, Salvatore Multari, Vasantha Palaniappan, Alexandra Tard, Wim Mennes

“…Considering that the exposure estimates for styrene and benzofuran are above the threshold of toxicological concern (TTC) value of 0.0025 kg/kg bw per day for DNA‐reactive mutagens and/or carcinogens and since further data are needed to clarify their potential genotoxicity, the Panel concluded that the potential safety concern for genotoxicity of the Primary Product cannot be ruled out.…”
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Update of the risk assessment of mineral oil hydrocarbons in food by EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, Jesús delMazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Jan Alexander, Christophe Goldbeck, Konrad Grob, Jose Ángel Gómez Ruiz, Olaf Mosbach‐Schulz, Marco Binaglia, James Kevin Chipman

“…Genotoxicity and carcinogenicity are associated with MOAH with three or more aromatic rings. …”
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Evaluation of efficiency of copper-nickel ferrite nanoparticles loaded onto multi-walled carbon nanotubes in activation of peroxymonosulfate for degradation of reactive black dye 5... by Mehdi Alhamd, Tayebeh Tabatabaie, Iman Parseh, Fazel Amiri, Nezamaddin Mengelizadeh

“…The presence of these solutions due to their toxicity and carcinogenic potential can be a threat to human health. …”
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Inflammatory cytokines and a diverse cervicovaginal microbiota associate with cervical dysplasia in a cohort of Hispanics living in Puerto Rico. by Eduardo Tosado-Rodríguez, Loyda B Mendez, Ana M Espino, Stephanie Dorta-Estremera, Edna E Aquino, Josefina Romaguera, Filipa Godoy-Vitorino

“…We found significant differences in the diversity and composition of the microbiota according to HPV type according to carcinogenic risk, cervical disease, and cytokine abundance. …”
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Comparative Risk Assessment of Three Native <i>Heliotropium</i> Species in Israel by Jakob A. Shimshoni, Shimon Barel, Patrick P. J. Mulder

“…Pyrrolizidine alkaloids (PAs) are genotoxic carcinogenic phytotoxins mostly prevalent in the Boraginaceae, Asteraceae and Fabaceae families. …”
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