Environmental Impact of the Reclaimed Sand Addition to Molding Sand with Furan and Phenol-Formaldehyde Resin—A Comparison by Mariusz Holtzer, Rafał Dańko, Angelika Kmita, Dariusz Drożyński, Michał Kubecki, Mateusz Skrzyński, Agnieszka Roczniak

“…However, more accurate investigations indicated that such molding sands subjected to high temperatures of liquid metal generated several harmful, even dangerous substances (carcinogenic and/or mutagenic) from the benzene, toluene, ethylbenzene and xylenes (BTEX) and polycyclic aromatic hydrocarbons groups (PAHs). …”
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Indole Derivative Interacts with Estrogen Receptor Beta and Inhibits Human Ovarian Cancer Cell Growth by Laura Verardi, Jessica Fiori, Vincenza Andrisano, Alessandra Locatelli, Rita Morigi, Marina Naldi, Carlo Bertucci, Elena Strocchi, Carla Boga, Gabriele Micheletti, Natalia Calonghi

“…However, the mechanism of its anti-carcinogenic activity is not well understood. Here, we offer a possible explanation of such an effect in the human ovarian cancer cell line IGROV1. …”
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Clinical Outcomes of the Deleterious Effects of Aluminum on Neuro-Cognition, Inflammation, and Health: A Review by Guilherme Renke, Vanessa Borges Pinheiro Almeida, Everton Almeida Souza, Suzana Lessa, Raila Linhares Teixeira, Leticia Rocha, Pamela Lopes Sousa, Bernardo Starling-Soares

“…Proven neurotoxicity in humans is the critical adverse effect of Al. A carcinogenic effect of Al has not been proven so far. …”
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Cellular Immune Response Induced by DNA Immunization of Mice with Drug Resistant Integrases of HIV-1 Clade A Offers Partial Protection against Growth and Metastatic Activity of Int... by Maria Isaguliants, Olga Krotova, Stefan Petkov, Juris Jansons, Ekaterina Bayurova, Dzeina Mezale, Ilze Fridrihsone, Athina Kilpelainen, Philip Podschwadt, Yulia Agapkina, Olga Smirnova, Linda Kostic, Mina Saleem, Oleg Latyshev, Olesja Eliseeva, Anastasia Malkova, Tatiana Gorodnicheva, Britta Wahren, Ilya Gordeychuk, Elizaveta Starodubova, Anastasia Latanova

“…Both were found safe in immunotoxicity tests in mice, with no inherent carcinogenicity: their expression did not enhance tumorigenic or metastatic potential of adenocarcinoma 4T1 cells. …”
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Optimization of the Decolorization of the Reactive Black 5 by a Laccase-like Active Cell-Free Supernatant from <i>Coriolopsis gallica</i> by Amal Ben Ayed, Bilel Hadrich, Giuliano Sciara, Anne Lomascolo, Emmanuel Bertrand, Craig B. Faulds, Héla Zouari-Mechichi, Eric Record, Tahar Mechichi

“…The textile industry generates huge volumes of colored wastewater that require multiple treatments to remove persistent toxic and carcinogenic dyes. Here we studied the decolorization of a recalcitrant azo dye, Reactive Black 5, using laccase-like active cell-free supernatant from <i>Coriolopsis gallica</i>. …”
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MULTIFOCAL BILATERAL METACHRONOUS BREAST CANCER IN MAN. CLINICAL CASE by E. K. Saribekyan, A. D. Zikiryakhodzhaev, M. Yu. Shkurnikov, E. V. Tyschenko, E. Yu. Fetisova, L. V. Moskvina, A. N. Petrov

“…This is primarily concerned with the improvement of diagnostics, medical treatment and increased expectation of life.The increase in incidence of MMT is due to such factors as increased average expectation of life, increased intensity of carcinogenic effects, urbanization, accumulation of hereditary loading and improved diagnostics of oncologic diseases. …”
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Non-coding RNA transcripts, incredible modulators of cisplatin chemo-resistance in bladder cancer through operating a broad spectrum of cellular processes and signaling mechanism by Mehrdad Hashem, Elaheh Mohandesi Khosroshahi, Melika Aliahmady, Morvarid Ghanei, Yasamin Soofi Rezaie, Yasamin alsadat Jafari, Fatemeh rezaei, Ramtin Khodaparast eskadehi, Kimia Kia Kojoori, faranak jamshidian, Noushin Nabavi, Mohsen Rashidi, Farzaneh Hasani Sadi, Afshin Taheriazam, Maliheh Entezari

“…The onset of BC is predominantly triggered by environmental and/or occupational exposures to carcinogens, such as tobacco. There are two distinct pathways by which BC can be developed, including non-muscle-invasive papillary tumors (NMIBC) and non-papillary (or solid) muscle-invasive tumors (MIBC). …”
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The deubiquitinating enzyme MINDY2 promotes pancreatic cancer proliferation and metastasis by stabilizing ACTN4 expression and activating the PI3K/AKT/mTOR signaling pathway by Peng Liu, Peng Liu, Songbai Liu, Changhao Zhu, Yongning Li, Ying Li, Xiaobin Fei, Junyi Hou, Xing Wang, Xing Wang, Yaozhen Pan, Yaozhen Pan

“…We also found that MINDY2 is associated with pro-carcinogenic factors such as epithelial-mesenchymal transition (EMT), inflammatory response, and angiogenesis; the ROC curve suggested that MINDY2 has a high diagnostic value in PC. …”
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Heterogeneous Fenton-like Photocatalytic Process towards the Eradication of Tetracycline under UV Irradiation: Mechanism Elucidation and Environmental Risk Analysis by Mohamadamin Amarzadeh, Moslem Azqandi, Kasra Nateq, Bahman Ramavandi, Nadeem A. Khan, Negin Nasseh

“…Eventually, the non-carcinogenic risk analysis in the surface water sample was carried out using multiple photocatalytic processes for the first time. …”
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The molecular mechanisms underlying arecoline-induced cardiac fibrosis in rats by Ku Chang-Wen, Day Cecilia Hsuan, Ou Hsiu-Chung, Ho Tsung-Jung, Chen Ray-Jade, Kumar Velmurugan Bharath, Lin Wen-Yuan, Huang Chih-Yang

“…Arecoline, the major areca nut alkaloid, has been classified as carcinogenic to humans as it adversely affects various organs, including the brain, heart, lungs, gastrointestinal tract, and reproductive organs. …”
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<i>Curcuma raktakanda</i> Induces Apoptosis and Suppresses Migration in Cancer Cells: Role of Reactive Oxygen Species by Shruti Mishra, Sumit Singh Verma, Vipin Rai, Nikee Awasthee, Jayadev S. Arya, Kaustabh K. Maiti, Subash C. Gupta

“…Collectively, the extract from <i>C. raktakanda</i> exhibited anti-carcinogenic activities in cancer cells. We are exploring whether the phytoconstituents, individually, or collectively contribute to the anti-cancer activities of <i>C. raktakanda</i>.…”
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Are There Betel Quid Mixtures Less Harmful than Others? A Scoping Review of the Association between Different Betel Quid Ingredients and the Risk of Oral Submucous Fibrosis by Nicola Cirillo, Peter Hung Duong, Wee Teng Er, Casey Thao Nhi Do, Manikkuwadura Eranda Harshan De Silva, Yining Dong, Sok Ching Cheong, Elizabeth Fitriana Sari, Michael J. McCullough, Pangzhen Zhang, Stephen S. Prime

“…BQ ingredients contain pro-carcinogenic bioactive compounds, but also potentially protective biomolecules, and we have shown recently that the chemical properties of different BQ recipes vary, which may explain the unequal prevalence of OSF and oral cancer in BQ users in different geographical regions. …”
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Anthocyanins from <i>Lycium ruthenicum</i> Murray Mitigate Cadmium-Induced Oxidative Stress and Testicular Toxicity by Activating the Keap1/Nrf2 Signaling Pathway by Mingran Dong, Juan Lu, Hongwei Xue, Yang Lou, Shuyang Li, Tao Liu, Zimian Ding, Xi Chen

“…Cadmium (Cd) is a hazardous heavy metal environmental pollutant that has carcinogenic, teratogenic, and mutagenic properties. …”
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Trace metals in transboundary (India–Myanmar–Bangladesh) anadromous fish Tenualosa ilisha and its consequences on human health by Afsana Parvin, Md Kamal Hossain, Afroza Parvin, M. Belal Hossain, Md Aftab Ali Shaikh, Mohammad Moniruzzaman, Badhan Saha, Priyanka Dey Suchi, Fahima Islam, Takaomi Arai

“…Also, there was no evidence of carcinogenic risk for consumers based on the evaluation of the TR value of metals (As, Pb, Cd, and Ni) due to Hilsa shad consumption.…”
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Ordinary Gasoline Emissions Induce a Toxic Response in Bronchial Cells Grown at Air-Liquid Interface by Tereza Cervena, Michal Vojtisek-Lom, Kristyna Vrbova, Antonin Ambroz, Zuzana Novakova, Fatima Elzeinova, Michal Sima, Vit Beranek, Martin Pechout, David Macoun, Jiri Klema, Andrea Rossnerova, Miroslav Ciganek, Jan Topinka, Pavel Rossner

“…Gasoline engine emissions have been classified as possibly carcinogenic to humans and represent a significant health risk. …”
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Clinico-Pathological Importance of TGF-β/Phospho-Smad Signaling during Human Hepatic Fibrocarcinogenesis by Katsunori Yoshida, Koichi Matsuzaki, Miki Murata, Takashi Yamaguchi, Kanehiko Suwa, Kazuichi Okazaki

“…This review addresses TGF-&beta;/Smad signal transduction in chronic liver injuries and carcinogenic processes. We also discuss the reversibility of Smad signaling after antiviral therapy.…”
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Distribution characteristics and risk assessment of heavy metals in seawater, sediment and shellfish in the inner and outer Daya Bay, Guangdong by Xiaodong Yu, Xiaodong Yu, Lianpeng Sun, Xinzhe Zhu, Guojian Bian, Wen Zhou, Qian Cao, Man Hong

“…This indicates that the probability of carcinogenic risk to the population from heavy metals in shellfish are all below unacceptable levels.…”
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Association of cigarette smoking with risk of colorectal cancer subtypes classified by gut microbiota by Jia-An Cai, Yong-Zhen Zhang, En-Da Yu, Wei-Qun Ding, Zhao-Shen Li, Liang Zhong, Quan-Cai Cai

“…The associations of smoking with increased odds of colorectal neoplasm significantly differed by gut microbiota enterotypes (p<0.05 for heterogeneity). An increase in carcinogenic bacteria (genus Escherichia shigella ) and a decrease in probiotics (family Lachnospiraceae and Ruminococcaceae ) in type II tumors may drive disease progression by upregulating oncogenic signaling pathways and inflammatory/oxidative stress response pathways, as well as protein phospholipase D1/2, cytochrome C, and prostaglandin-endoperoxide synthase 2 expression. …”
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Methyltransferases mediate cell memory of a genotoxic insult by Engelward, Bevin P., Rugo, Rebecca, Mutamba, James Tendai, Yee, Tiffany L., Chaillet, J. R., Greenberger, Joel S., Mohan, K. N.

“…Collectively, our results impact the current understanding of risks from toxin exposures and suggest modes of intervention for suppressing genomic instability in people exposed to carcinogenic genotoxins.…”
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NRF2 and the Ambiguous Consequences of Its Activation during Initiation and the Subsequent Stages of Tumourigenesis by Holly Robertson, Albena T. Dinkova-Kostova, John D. Hayes

“…In normal cells, activation of NRF2 by a thiol-reactive stressor helps prevent, for a limited period of time, the initiation of cancer by chemical carcinogens through induction of genes encoding drug-metabolising enzymes. …”
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