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5661
Environmental Impact of the Reclaimed Sand Addition to Molding Sand with Furan and Phenol-Formaldehyde Resin—A Comparison
Published 2020-10-01“…However, more accurate investigations indicated that such molding sands subjected to high temperatures of liquid metal generated several harmful, even dangerous substances (carcinogenic and/or mutagenic) from the benzene, toluene, ethylbenzene and xylenes (BTEX) and polycyclic aromatic hydrocarbons groups (PAHs). …”
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5662
Indole Derivative Interacts with Estrogen Receptor Beta and Inhibits Human Ovarian Cancer Cell Growth
Published 2020-09-01“…However, the mechanism of its anti-carcinogenic activity is not well understood. Here, we offer a possible explanation of such an effect in the human ovarian cancer cell line IGROV1. …”
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5663
Clinical Outcomes of the Deleterious Effects of Aluminum on Neuro-Cognition, Inflammation, and Health: A Review
Published 2023-05-01“…Proven neurotoxicity in humans is the critical adverse effect of Al. A carcinogenic effect of Al has not been proven so far. …”
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5664
Cellular Immune Response Induced by DNA Immunization of Mice with Drug Resistant Integrases of HIV-1 Clade A Offers Partial Protection against Growth and Metastatic Activity of Int...
Published 2021-06-01“…Both were found safe in immunotoxicity tests in mice, with no inherent carcinogenicity: their expression did not enhance tumorigenic or metastatic potential of adenocarcinoma 4T1 cells. …”
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5665
Optimization of the Decolorization of the Reactive Black 5 by a Laccase-like Active Cell-Free Supernatant from <i>Coriolopsis gallica</i>
Published 2022-05-01“…The textile industry generates huge volumes of colored wastewater that require multiple treatments to remove persistent toxic and carcinogenic dyes. Here we studied the decolorization of a recalcitrant azo dye, Reactive Black 5, using laccase-like active cell-free supernatant from <i>Coriolopsis gallica</i>. …”
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5666
MULTIFOCAL BILATERAL METACHRONOUS BREAST CANCER IN MAN. CLINICAL CASE
Published 2015-04-01“…This is primarily concerned with the improvement of diagnostics, medical treatment and increased expectation of life.The increase in incidence of MMT is due to such factors as increased average expectation of life, increased intensity of carcinogenic effects, urbanization, accumulation of hereditary loading and improved diagnostics of oncologic diseases. …”
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5667
Non-coding RNA transcripts, incredible modulators of cisplatin chemo-resistance in bladder cancer through operating a broad spectrum of cellular processes and signaling mechanism
Published 2024-06-01“…The onset of BC is predominantly triggered by environmental and/or occupational exposures to carcinogens, such as tobacco. There are two distinct pathways by which BC can be developed, including non-muscle-invasive papillary tumors (NMIBC) and non-papillary (or solid) muscle-invasive tumors (MIBC). …”
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5668
The deubiquitinating enzyme MINDY2 promotes pancreatic cancer proliferation and metastasis by stabilizing ACTN4 expression and activating the PI3K/AKT/mTOR signaling pathway
Published 2023-05-01“…We also found that MINDY2 is associated with pro-carcinogenic factors such as epithelial-mesenchymal transition (EMT), inflammatory response, and angiogenesis; the ROC curve suggested that MINDY2 has a high diagnostic value in PC. …”
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5669
Heterogeneous Fenton-like Photocatalytic Process towards the Eradication of Tetracycline under UV Irradiation: Mechanism Elucidation and Environmental Risk Analysis
Published 2023-06-01“…Eventually, the non-carcinogenic risk analysis in the surface water sample was carried out using multiple photocatalytic processes for the first time. …”
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5670
The molecular mechanisms underlying arecoline-induced cardiac fibrosis in rats
Published 2021-11-01“…Arecoline, the major areca nut alkaloid, has been classified as carcinogenic to humans as it adversely affects various organs, including the brain, heart, lungs, gastrointestinal tract, and reproductive organs. …”
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5671
<i>Curcuma raktakanda</i> Induces Apoptosis and Suppresses Migration in Cancer Cells: Role of Reactive Oxygen Species
Published 2019-04-01“…Collectively, the extract from <i>C. raktakanda</i> exhibited anti-carcinogenic activities in cancer cells. We are exploring whether the phytoconstituents, individually, or collectively contribute to the anti-cancer activities of <i>C. raktakanda</i>.…”
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5672
Are There Betel Quid Mixtures Less Harmful than Others? A Scoping Review of the Association between Different Betel Quid Ingredients and the Risk of Oral Submucous Fibrosis
Published 2022-05-01“…BQ ingredients contain pro-carcinogenic bioactive compounds, but also potentially protective biomolecules, and we have shown recently that the chemical properties of different BQ recipes vary, which may explain the unequal prevalence of OSF and oral cancer in BQ users in different geographical regions. …”
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5673
Anthocyanins from <i>Lycium ruthenicum</i> Murray Mitigate Cadmium-Induced Oxidative Stress and Testicular Toxicity by Activating the Keap1/Nrf2 Signaling Pathway
Published 2024-03-01“…Cadmium (Cd) is a hazardous heavy metal environmental pollutant that has carcinogenic, teratogenic, and mutagenic properties. …”
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5674
Trace metals in transboundary (India–Myanmar–Bangladesh) anadromous fish Tenualosa ilisha and its consequences on human health
Published 2023-11-01“…Also, there was no evidence of carcinogenic risk for consumers based on the evaluation of the TR value of metals (As, Pb, Cd, and Ni) due to Hilsa shad consumption.…”
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5675
Ordinary Gasoline Emissions Induce a Toxic Response in Bronchial Cells Grown at Air-Liquid Interface
Published 2020-12-01“…Gasoline engine emissions have been classified as possibly carcinogenic to humans and represent a significant health risk. …”
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5676
Clinico-Pathological Importance of TGF-β/Phospho-Smad Signaling during Human Hepatic Fibrocarcinogenesis
Published 2018-06-01“…This review addresses TGF-β/Smad signal transduction in chronic liver injuries and carcinogenic processes. We also discuss the reversibility of Smad signaling after antiviral therapy.…”
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5677
Distribution characteristics and risk assessment of heavy metals in seawater, sediment and shellfish in the inner and outer Daya Bay, Guangdong
Published 2022-12-01“…This indicates that the probability of carcinogenic risk to the population from heavy metals in shellfish are all below unacceptable levels.…”
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5678
Association of cigarette smoking with risk of colorectal cancer subtypes classified by gut microbiota
Published 2023-08-01“…The associations of smoking with increased odds of colorectal neoplasm significantly differed by gut microbiota enterotypes (p<0.05 for heterogeneity). An increase in carcinogenic bacteria (genus Escherichia shigella ) and a decrease in probiotics (family Lachnospiraceae and Ruminococcaceae ) in type II tumors may drive disease progression by upregulating oncogenic signaling pathways and inflammatory/oxidative stress response pathways, as well as protein phospholipase D1/2, cytochrome C, and prostaglandin-endoperoxide synthase 2 expression. …”
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5679
Methyltransferases mediate cell memory of a genotoxic insult
Published 2010“…Collectively, our results impact the current understanding of risks from toxin exposures and suggest modes of intervention for suppressing genomic instability in people exposed to carcinogenic genotoxins.…”
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5680
NRF2 and the Ambiguous Consequences of Its Activation during Initiation and the Subsequent Stages of Tumourigenesis
Published 2020-12-01“…In normal cells, activation of NRF2 by a thiol-reactive stressor helps prevent, for a limited period of time, the initiation of cancer by chemical carcinogens through induction of genes encoding drug-metabolising enzymes. …”
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