-
6181
TP53 mutations in Romanian patients with colorectal cancer
Published 2023-07-01“…The discovery of novel mutations following the efforts of The Cancer Genome Atlas and other large-scale cancer genome sequencing projects may be further evidence of the heterogeneous nature of mutations in cancer and may indicate that the identification of carcinogenic mutations is not yet saturated. Further sequencing is therefore needed, especially in less studied populations. …”
Get full text
Article -
6182
ANTIBODIES TO BENZO[A]PYRENE, ESTRADIOL AND PROGESTERONE AND GENE POLYMORPHISMS OF CYTOKINES: ASSOCIATIONS WITH LUNG CANCER IN MEN
Published 2018-03-01“…Previous studies have revealed associations of antibodies, specific to chemical carcinogens and steroid hormones with lung cancer in men. …”
Get full text
Article -
6183
Berberine inhibits intestinal carcinogenesis by suppressing intestinal pro-inflammatory genes and oncogenic factors through modulating gut microbiota
Published 2022-05-01“…Therefore, it was concluded that suppression of pro-inflammatory genes and carcinogens factors by modulating gut microbiota was an important pathway for BBR to inhibit tumor growth in conventional mice.…”
Get full text
Article -
6184
Indoor wood-burning from stoves and fireplaces and incident lung cancer among Sister Study participants
Published 2023-08-01Get full text
Article -
6185
<i>Bacillus subtilis</i> Simultaneously Detoxified Aflatoxin B1 and Zearalenone
Published 2024-02-01“…The co-occurrence of aflatoxin B1 (AFB1) and zearalenone (ZEN) in grain-based food and animal feed poses significant health risks to humans and animals due to their potent mutagenic, cytotoxic, and carcinogenic properties. Conventional physical and chemical methods are insufficient for effectively detoxifying multiple mycotoxins present in food and feed. …”
Get full text
Article -
6186
Teeth discolouration and prescribed slimming magistral formula: a case report
Published 2021-04-01“…Stains may have originated from tainted plant extracts (containing tannins or uncontrolled/unlabeled heavy metals − Fe, Cu, Cd, Sn − due to phytogeography; contaminants) or PhP (an acid–base titration reagent, changing colour according to pH), here used as a stimulant laxative, withdrawn from medicines in many European countries due to its carcinogenic potential. The hypotheses raised warrant further investigation and clarification of the role of drugs/botanicals and contaminants in tooth staining.…”
Get full text
Article -
6187
PATTERNS OF THE REGIONAL URANIUM STATUS FORMATION ON THE EXAMPLE OF THE REPUBLIC OF BASHKORTOSTAN
Published 2023-10-01“…Uranium is a radioactive, carcinogenic, toxic element that can be accumulated in human body and cause various pathologies (the risk of kidney dysfunction, the development of leukemia, colorectal cancer etc.). …”
Get full text
Article -
6188
Identification and characterization of CLEC11A and its derived immune signature in gastric cancer
Published 2024-01-01“…The expression and carcinogenic effects of CLEC11A in GC were verified by qRT−PCR, cell migration, invasion, cell cycle analysis, and in vivo model analysis. …”
Get full text
Article -
6189
Gold Nanoparticles Inhibit PMA-Induced MMP-9 Expression via microRNA-204-5p Upregulation and Deactivation of NF-κBp65 in Breast Cancer Cells
Published 2023-05-01“…These novel therapeutic potentials of AuNPs on stimulated BC cells provide novel suggestions that AuNPs inhibit carcinogenic activity via inverse regulation of microRNAs.…”
Get full text
Article -
6190
Revealing oxidative stress-related genes in osteoporosis and advanced structural biological study for novel natural material discovery regarding MAPKAPK2
Published 2022-11-01“…Then, Novel Materials Discovery demonstrated that two compounds, ZINC000014951634 and ZINC000040976869, were found binding to MAPKAPK2 with a favorable interaction energy together with a high binding affinity, relatively low hepatoxicity and carcinogenicity, high aqueous solubility and intestinal absorption levels, etc., indicating that the two compounds were ideal potential inhibitor materials targeting MAPKAPK2.ConclusionThis study found a group set of OS-related biomarkers of OP, providing further insights for OS functions in the development of OP. …”
Get full text
Article -
6191
CYTOKINE-PRODUCING RESOURCE OF IMMUNOCOMPETENT BLOOD CELLS IN BREAST TUMORS AND PRECANCEROUS CHANGES OF MAMMARY GLAND
Published 2018-11-01“…A variety of both benign and malignant events in mammary gland, the features of neoplastic growth and age of the patients require new approaches to study of carcinogenic events in mammary gland. As based on the known role of cytokines in genesis of malignancies, the aim of the study was to evaluate the cytokine-producing resource of immunocompetent blood cells in malignant, benign and precancerous mammary disorders. …”
Get full text
Article -
6192
Degradasi Zat Warna Direct Red-23 Secara Fotolisis dengan Katalis C-N-codoped TiO2
Published 2017-11-01“…Wastes generated from textile industrial processes are generally non-biodegradable organic compounds containing azo compounds and carcinogenic. Direct red-23 dye was degraded by photolysis UV Light method, solar irradiation, without and addition of C-N-codoped TiO2 catalyst. …”
Get full text
Article -
6193
Accumulation and distribution of mercury in agricultural soils, food crops and associated health risks: A case study of Shenda gold mine-Geita Tanzania
Published 2023-04-01“…Target hazard quotient (THQ) was < 1 due to consumption of vegetables while THQ value for rice was >1, indicating a potential non-carcinogenic risk to adult population from the consumption of rice grain from the study area. …”
Get full text
Article -
6194
The Presence of Aflatoxin M<sub>1</sub> in Milk and Milk Products in Bangladesh
Published 2021-06-01“…However, the presence of aflatoxin B<sub>1</sub> (AFB<sub>1</sub>) in the feed of dairy cattle results in contamination of milk and dairy products with aflatoxin M<sub>1</sub> (AFM<sub>1</sub>), a toxic metabolite of the carcinogenic mycotoxin. With the aim to determine AFM<sub>1</sub> concentrations in milk and milk products consumed in Bangladesh, in total, 145 samples were collected in four divisional regions (Sylhet, Dhaka, Chittagong, and Rajshahi). …”
Get full text
Article -
6195
Mycotoxins at the Start of the Food Chain in Costa Rica: Analysis of Six <i>Fusarium</i> Toxins and Ochratoxin A between 2013 and 2017 in Animal Feed and Aflatoxin M<sub>1</sub> in...
Published 2019-05-01“…Mycotoxins are secondary metabolites, produced by fungi of genera <i>Aspergillus</i>, <i>Penicillium</i> and <i>Fusarium</i> (among others), which produce adverse health effects on humans and animals (carcinogenic, teratogenic and immunosuppressive). In addition, mycotoxins negatively affect the productive parameters of livestock (e.g., weight, food consumption, and food conversion). …”
Get full text
Article -
6196
Volatile Organic Compounds Emitted by <i>Aspergillus flavus</i> Strains Producing or Not Aflatoxin B1
Published 2021-10-01“…<i>Aspergillus flavus</i> is a phytopathogenic fungus able to produce aflatoxin B1 (AFB1), a carcinogenic mycotoxin that can contaminate several crops and food commodities. …”
Get full text
Article -
6197
Genetic diversity, haplotype analysis, and prevalence of Hepatitis B virus MHR mutations among isolates from Kenyan blood donors.
Published 2023-01-01“…These viral genotypes and variants, in addition to carcinogenic risk, can be key predictors of therapy response and outcomes. …”
Get full text
Article -
6198
miR-3200 accelerates the growth of liver cancer cells by enhancing Rab7A
Published 2023-12-01“…Furthermore, our results suggest that miR-3200 enhances expression of RAB7A, and then Rab7A regulates the carcinogenic function of miR-3200 by increasing telomere remodeling in human liver cancer. …”
Get full text
Article -
6199
Examining differences in menstrual and intimate care product use by race/ethnicity and education among menstruating individuals
Published 2023-12-01“…However, these scent-altering products may increase exposure to carcinogenic and endocrine-disrupting chemicals. Prior research has not adequately characterized demographic differences in product use. …”
Get full text
Article -
6200
The Association between Selective Serotonin Reuptake Inhibitors (SSRIs) Use and the Risk of Bladder Cancer: A Nationwide Population-Based Cohort Study
Published 2020-05-01“…Background: Past studies suggest mixed associations between selective serotonin reuptake inhibitor (SSRI) prescription and carcinogenic risk. There is no epidemiological study reporting on the association between SSRI use and the incidence of bladder cancer. …”
Get full text
Article