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6221
The proliferation of atypical hepatocytes and CDT1 expression in noncancerous tissue are associated with the postoperative recurrence of hepatocellular carcinoma
Published 2022-11-01“…We found that the strong degree of atypical hepatocytes and high CDT1 mRNA expression represent a high carcinogenic state of the liver. Thus, we consider the evaluation of degree of these could support the personalized medicine.…”
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6222
Whole exome sequencing and machine learning germline analysis of individuals presenting with extreme phenotypes of high and low risk of developing tobacco-associated lung adenocarc...
Published 2024-04-01“…Yet, while some heavy smokers develop lung cancer at a young age, other heavy smokers never develop it, even at an advanced age, suggesting a remarkable variability in the individual susceptibility to the carcinogenic effects of tobacco. We characterized the germline profile of subjects presenting these extreme phenotypes with Whole Exome Sequencing (WES) and Machine Learning (ML). …”
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6223
Prevalence, knowledge and attitude toward electronic cigarette use among male health colleges students in Saudi Arabia—A cross-sectional study
Published 2022-10-01“…Many students had misconceptions and a low level of knowledge about ECs, such as recognizing them as smoking-cessation tools and not knowing whether toxic and carcinogenic components levels in ECs are similar to conventional cigarettes, respectively. …”
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6224
Mobile phone use and brain tumour risk – COSMOS, a prospective cohort study
Published 2024-03-01“…Background: Each new generation of mobile phone technology has triggered discussions about potential carcinogenicity from exposure to radiofrequency electromagnetic fields (RF-EMF). …”
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6225
Benzo[a]pyrene exposure affects colorectal cancer susceptibility by regulating ERβ-mediated LINC02977 transcription
Published 2024-02-01“…The study also revealed that BaP and estradiol (E2) had different carcinogenic effects, with BaP promoting cell proliferation and inhibiting apoptosis, while E2 had the opposite effects. …”
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6226
Implications of oral dysbiosis and HPV infection in head and neck cancer: from molecular and cellular mechanisms to early diagnosis and therapy
Published 2023-12-01“…Oral dysbiosis is associated with the evolution of HNCs, through multiple mechanisms such as inflammation, genotoxins release, modulation of the innate and acquired immune response, carcinogens and anticarcinogens production, generation of oxidative stress, induction of mutations. …”
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6227
Baseline data and associations between urinary biomarkers of polycyclic aromatic hydrocarbons, blood pressure, hemogram, and lifestyle among wildland firefighters
Published 2024-03-01“…Firefighters who smoke presented 3-times higher total concentration of OHPAHs than non-smokers (p < 0.001); non-smoker females presented 2-fold lower total OHPAHs (p = 0.049) than males. 1-hydroxypyrene was below the recommended occupational biological exposure value (2.5 μg/L), and the metabolite of carcinogenic PAH (benzo(a)pyrene) was not detected. Blood pressure was above 120/80 mmHg in 71% of subjects. …”
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6228
Histidine-rich glycoprotein in metabolic dysfunction-associated steatohepatitis-related disease progression and liver carcinogenesis
Published 2024-02-01“…When submitted to the pro-carcinogenic protocol, HRG−/− mice showed a significant decrease in the volume and number of HCC nodules in relation to decreased infiltration of macrophages producing pro-inflammatory mediators, including IL-1β, IL-6, IL-12, IL-10, and VEGF as well as impaired angiogenesis. …”
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6229
Hydrochemical Appraisal and Driving Forces of Groundwater Quality and Potential Health Risks of Nitrate in Typical Agricultural Area of Southwestern China
Published 2023-11-01“…The entropy-weighted water quality index ranged from 15 to 94, suggesting that the groundwater samples were suitable for drinking purposes. Non-carcinogenic human health risks followed the order of children > adult females > adult males, within the average values of 0.30, 0.21, and 0.18, respectively. …”
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6230
Prevalence and Risk Factors of Infection with High Risk Human Papilloma Viruses among HIV-Positive Women with Clinical Manifestations of Tuberculosis in a Middle-Income Country
Published 2021-06-01“…Women living with HIV-1 are at high risk of infection with human papillomavirus of high carcinogenic risk (HR HPVs). <i>M. tuberculosis</i> (TB) promotes HPV infection and increases the risk to develop HPV-associated cancer. …”
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6231
Comparison of Different Self-Sampling Devices for Molecular Detection of Human Papillomavirus (HPV) and Other Sexually Transmitted Infections (STIs): A Pilot Study
Published 2022-02-01“…Background: Cervical cancer is the fourth most common cancer in women, and it is well known that high-risk human papillomavirus (hrHPV) infections are the necessary carcinogenic factors for the development of cervical tumors. …”
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6232
A novel anoikis-related prognostic signature associated with prognosis and immune infiltration landscape in clear cell renal cell carcinoma
Published 2022-10-01“…TIDE score showed a promising immunotherapy response of ccRCC patients in different risk subgroups and cluster subgroups.Conclusion: Our study revealed that ARGs play a carcinogenic role in ccRCC. Additionally, we firstly integrated multiple ARGs to establish a risk-predictive model. …”
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6233
Organochlorine pesticides and risk of papillary thyroid cancer in U.S. military personnel: a nested case-control study
Published 2024-03-01“…Environmental Protection Agency has classified HCB and other OCPs we studied here as probable human carcinogens. Our findings of increased risks for classical PTC associated with increased concentrations of HCB and β-HCCH, which were stronger among females, should be replicated in future studies of other populations.…”
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6234
PM<sub>2.5</sub>-Related Health Risk during Chinese Spring Festival in Taizhou, Zhejiang: The Health Impacts of COVID-19 Lockdown
Published 2022-12-01“…The noncarcinogenic risk posed by As, Co, Mn, and Ti in 2018 and As and Mn in 2020 was significant. The carcinogenic risk posed by As, Cr(VI), and Pb exceeded the accepted precautionary limit (1 × 10<sup>−6</sup>) in both years. …”
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6235
The Inhibitory Effect of Early Pregnancy Factor on Red Meat Neu5Gc-Mediated Antibody Production in CMAH<sup>−/−</sup> Mice
Published 2024-03-01“…This is due to the presence of a potential carcinogenic compound in red meat called <i>N</i>-ethanol neuraminic acid (Neu5Gc). …”
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6236
Efficiency of a novel nitrogen-doped Fe3O4 impregnated biochar (N/Fe3O4@BC) for arsenic (III and V) removal from aqueous solution: Insight into mechanistic understanding and reusab...
Published 2022-11-01“…Worldwide, arsenic contamination has become a matter of extreme importance owing to its potential toxic, carcinogenic and mutagenic impact on human health and the environment. …”
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6237
A computational approach to evaluate caffeoylquinic acids and flavonoids in Pluchea indica Less. leaves as potential anti-HIV agents
Published 2024-07-01“…Most test compounds did not cause hepatotoxicity, carcinogenicity, or mutagenicity. All test compounds have no cytotoxic potential. …”
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6238
Abundance, Source Apportionment and Health Risk Assessment of Polycyclic Aromatic Hydrocarbons and Nitro-Polycyclic Aromatic Hydrocarbons in PM<sub>2.5</sub> in the Urban Atmospher...
Published 2022-09-01“…The results of the total incremental lifetime cancer risk (ILCR) via three exposure routes (ingestion, inhalation and dermal absorption) for males and females during the four seasons indicated a low long-term potential carcinogenic risk, with values ranging from 10<sup>−10</sup> to 10<sup>−7</sup>. …”
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6239
miR-624 accelerates the growth of liver cancer cells by inhibiting EMC3
Published 2023-12-01“…Strikingly, excessive MEC3 abrogates the carcinogenic functions of miR-624. Importantly, our findings indicate that miR-624 affects some signaling pathway in liver cancer, including Wnt signaling pathway,Hippo signaling pathway,mTOR signaling pathway, Ras signaling pathway,MAPK signaling pathway,PI3K-Akt signaling pathway, erbB signaling pathway. …”
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6240
Synthesis of Electrospun TiO<sub>2</sub> Nanofibers and Characterization of Their Antibacterial and Antibiofilm Potential against Gram-Positive and Gram-Negative Bacteria
Published 2020-09-01“…Recently, titanium dioxide (TiO<sub>2</sub>) nanomaterials have gained increased attention because of their cost-effective, safe, stable, non-toxic, non-carcinogenic, photocatalytic, bactericidal, biomedical, industrial and waste-water treatment applications. …”
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