Identification and validation of a novel tumor driver gene signature for diagnosis and prognosis of head and neck squamous cell carcinoma by Shixian Liu, Shixian Liu, Shixian Liu, Weiwei Liu, Weiwei Liu, Weiwei Liu, Zhao Ding, Zhao Ding, Zhao Ding, Xue Yang, Xue Yang, Xue Yang, Yuan Jiang, Yuan Jiang, Yuan Jiang, Yu Wu, Yu Wu, Yu Wu, Yehai Liu, Jing Wu

“…Objective: Head and neck squamous cell carcinoma (HNSCC) is a common heterogeneous cancer with complex carcinogenic factors. However, the current TNM staging criteria to judge its severity to formulate treatment plans and evaluate the prognosis are particularly weak. …”
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Phytochemical Characterization, Antioxidant and Anti-Inflammatory Effects of <i>Cleome arabica</i> L. Fruits Extract against Formalin Induced Chronic Inflammation in Female Wistar... by Ikram Allagui, Mabrouk Horchani, Nourhene Zammel, Maroua Jalouli, Abdelfatteh Elfeki, Choumous Kallel, Lamjed Mansour, Salah Alwasel, Abdel Halim Harrath, Hichem Ben Jannet, Mohamed Salah Allagui, Kheiria Hcini

“…In specific, the natural compounds from the Capparaceae family which has been proved to have antioxidant, anti-inflammatory, antimicrobial and anti-carcinogenic activities, by several studies. <i>Cleome arabica</i> L. …”
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Development and Preliminary Characterization of Polyester-Urethane Microparticles Used in Curcumin Drug Delivery System for Oropharyngeal Cancer by Alexandru Chioreanu, Ion Cristian Mot, Delia Ioana Horhat, Nicolae Constantin Balica, Cristian Andrei Sarau, Raluca Morar, Eugenia Maria Domuta, Catalin Dumitru, Rodica Anamaria Negrean, Bogdan Andrei Bumbu, Madhavi Ravulapalli, Satish Alambaram, Raja Akshay, Marius Pricop

“…<i>Background and Objectives</i>: Curcumin (Cc) as an active substance is known for its anti-inflammatory, anticoagulant, antioxidant, and anti-carcinogenic effects, together with its role in cholesterol regulation, and its use in different gastrointestinal derangements. …”
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Optimization of propolis ultrasound-assisted extract and identification of its phytochemical and wound healing properties by Najihah, Yusof

“…Natural products like propolis have captivated endless attention among researchers due to the presence of various beneficially active compounds such as phenolic acids and flavonoids and these compounds possess anti- inflammatory, anti- oxidative, anti- microbial, anti- carcinogenic, wound healing properties and many others. …”
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Hepatitis B surface antigen expression impairs endoplasmic reticulum stress-related autophagic flux by decreasing LAMP2 by Yaojie Liang, Xufeng Luo, Stefan Schefczyk, Lorraine T. Muungani, Hui Deng, Baoju Wang, Hideo A. Baba, Mengji Lu, Heiner Wedemeyer, Hartmut H. Schmidt, Ruth Broering

“…Methods: Hemizygous Tg(Alb1HBV)44Bri/J mice were examined for HBsAg-induced carcinogenic events. Gene set-enrichment analysis identified significant signatures in HBsAg-transgenic mice that correlated with endoplasmic reticulum (ER) stress, unfolded protein response, autophagy and proliferation. …”
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Penilaian Pencemaran Logam Berat Cd, Pb, Cu, dan Zn pada Sedimen Permukaan Perairan Matras, Sungailiat, Bangka by Mohammad Agung Nugraha, Aditya Pamungkas, Indra Ambalika Syari, Suci Puspita Sari, Umroh Umroh, Mu’alimah Hudatwi, Eva Utami, Irma Akhrianti, Agung Priyambada

“…Heavy metals are toxic and carcinogenic to aquatic biota. Sediment is a carrier of heavy metal pollutants and can act as a “sink” and a “source”. …”
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Immunological imbalance, gene polymorphism of biotransformation enzymes, and steroid hormone receptors in tumors in breast cancer patients by A. N. Glushkov, E. G. Polenok, L. A. Gordeeva, S. A. Mun, M. V. Kostyanko, A. V. Antonov, N. N. Verzhbitskaya, E. N. Voronina, G. I. Kolpinskiy

“…The decrease of steroid receptors expression seems to depend on action of genotoxic metabolites of environmental carcinogens (particularly, benzo[a]pyrene, BP) and endogenous steroids (in particular, estradiol, E2). …”
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Health risk assessment through probabilistic sensitivity analysis of carbon monoxide and fine particulate transportation exposure by E. Ernyasih, A. Mallongi, A. Daud, S. Palutturi, S. Stang, R. Thaha, E. Ibrahim, W. Al Madhoun

“…Hazard quotient and target hazard quotient calculations were used to estimate the non-carcinogenic health risks associated with exposure to these substances for both community adults and school children. …”
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N-arylsulfonyl-2-aroylamino-1,4-quinone imines and their hydrogenated analogues: prediction of toxicity and prospects for use as diuretics by K.V. Sokolova, O.A. Podpletnia, S.О. Konovalova, A.P. Avdeenko, O.Z. Komarovska-Porokhnyavets, V.I. Lubеnets, S.I. Kovalenko

“…Based on the results of the calculation, it was predicted that N-arylsulfonyl-2-aroylamino-1,4-quinone imines (2) and their hydrogenated analogues (3) have hepato-(immuno-, cyto-) toxicity, carcinogenicity (mutagenicity) similar to natural quinones and diuretics (toxicity class IV). …”
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Risk assessment of dietary exposure to 3-monochloropropane-1,2-diol esters in infant formula powders in Shanghai by Luxin QIN, Baozhang LUO, Hua CAI, Jingjin YANG, Danping QIU, Hong LIU, Chunfeng WU

“…The pollution of 3-monochloropropane-1,2-diol esters (3-MCPDE) is the most prominent. 3-MCPDE is hydrolyzed in organisms to 3-monochloropropane-1,2-diol which has been shown to have reproductive toxicity, nephrotoxicity, and potential carcinogenicity. Infant formula powders can be polluted by 3-MCPDE when refined edible oils are added during production.ObjectiveTo assess the risk of exposure to 3-MCPDE related to the consumption of infant formula powders for children aged 0-3 years in Shanghai market using the food consumption data and the data of 3-MCPDE contamination in these foods.MethodsGas chromatography-mass spectrometry was used to determine 3-MCPDE in 133 samples of infant formula powders in Shanghai. …”
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Methods and Prospects for Determination of Mycotoxins in Medicinal Herbal Raw Materials (Review) by O. V. Trineeva

“…Currently, the development of express methods for determining the content of MT with mutagenic, teratogenic and carcinogenic properties is of particular importance in the food and pharmaceutical industries. …”
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Spatial Monitoring of Wind Erosion and Some Heavy Metals in Suspended Load of Tabas City by H. Emami, M. Memarzadeh

“…In addition, the spatial variation of heavy metals indicated that the concentrations of studied heavy metals (Mn, Fe, Cu, and Zn) in suspended particles, especially in the western, northwestern, and northern in spring, are very high and they can cause carcinogenic effects on human life. Therefore, the management practices should be mostly made in these directions to control or reduce soil erosion and reduce its damage effects.…”
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Development of an analytical approach for determination of acrylamide content in roasted date seed varieties by Paniz Khaloo Kermani, Marzieh Moeenfard, Reza Farhoosh, Arminda Alves

“…However, along with color and aroma changes, carcinogenic substance such as acrylamide may also formed during the roasting process. …”
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Influence of MTHFR polymorphism, alone or in combination with smoking and alcohol consumption, on cancer susceptibility by Huang Yonghui, Hu Qiurui, Wei Zhenxia, Chen Li, Luo Ying, Li Xiaojie, Li Cuiping

“…The association between the C677T polymorphism and cancer risk among smokers was found to be significant, suggesting that the combination of tobacco and the C677T polymorphism may enhance the carcinogenic process, particularly in liver cancer. However, no similar relationship was observed for the A1298C polymorphism. …”
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Polimorfismos en los genes de desintoxicación CYP1A1, CYP2E1, GSTT1 y GSTM1 en la susceptibilidad al cáncer gástrico by Auxiliadora González, Vanessa Ramírez, Patricia Cuenca, Rafaela Sierra

“…Cytochrome P450 (CYP) and glutathione S-transferase (GST) enzymes are involved in activation and detoxification of many potential carcinogens. Genetic polymorphisms in those enzymes have been found to influence the interindividual susceptibility to cancer. …”
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DEJAR DE FUMAR: FACTOR PROTECTOR DE CÁNCER GÁSTRICO DEIXAR DE FUMAR: FATOR PROTETOR DE CÂNCER GÁSTRICO QUIT SMOKING: PROTECTION FACTOR TO GASTRIC CANCER by Eduardo Castaño Molina, Hernán Parra Sánchez

“…Among the external factors are the occupational and/or environmental exhibitions to carcinogenic or procarcinogens compounds. One of them is cigarette smoke, and therefore its possible association with GC risk was explored. …”
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Analysis of DNA damage and repair responses in cerium exposed cells and hepatocyte spheroids by Chao, Christy.

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Decolorization of metanil yellow dye by free and immobilized bacterial cells by Muliadi, Fatin Natasha Amira

“…The presence of dyes in the textile effluent also causes an unpleasant appearance by imparting the color and also their breakdown products (colorless amines) which are toxic, carcinogenic and mutagenic. One of the examples of azo dyes is Metanil Yellow (MY) dye. …”
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Biodegradation of phenol by locally isolated Acinetobacter sp. strain AQ5NOL 1 and purification of phenol hydroxylase by Ahmad, Siti Aqlima

“…These pollutants are persistent in nature and are considered highly hazardous due to their toxicity, mutagenicity and carcinogenicity towards most biological processes even at low concentrations. …”
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Optimization of glyoxalation for alkali lignin used as bulking agent in wood by Ang, Aik Fei

“…The development of bulking agent that made of modified alkali lignin, the glyoxalated alkali lignin is crucial to mitigate the concentrations of petrochemical derived phenol and carcinogenic formaldehyde. The objective of this study was to enhance the structural homogeneity and chemical reactivity of alkali lignin through sequential organic solvents fractionation and glyoxalation, and to enhance the dimensional stability of jelutong (Dyera costulata) wood using glyoxalated alkali lignin incorporated with low molecular weight phenol formaldehyde resin as bulking agent. …”
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