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1021
IL-1 receptor–associated kinase-3 acts as an immune checkpoint in myeloid cells to limit cancer immunotherapy
Published 2023-04-01“…IRAK3 deficiency delayed the growth of carcinogen-induced and oncogene-driven murine cancer cells and induced enhanced activation in myeloid cells and T cells. …”
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1022
Primary Peritoneal Mesothelioma: Diagnostic Challenges of This Lethal Imposter
Published 2022-11-01“…The pathogenesis of all forms of mesothelioma is strongly associated with industrial pollutants, of which asbestos is the principal carcinogen. Characteristically, asbestos exposure has a strong relationship with mesothelioma of the pleura, but the peritoneal cavity is the second most commonly affected site. …”
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1023
A Novel, Simple, and Reliable Spectrophotometric Determination of Total Hexavalent Chromium by Complexation with a New Reagent of Thiazole Linked to 2H-Chromen-2-One
Published 2023-01-01“…Hexavalent chromium is a known environmental contaminant and carcinogen. In the current work, a simple, rapid, and reliable direct spectrophotometric method was used for the determination of total Cr (VI) in environmental samples. …”
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1024
Design of a Prototype Photoreactor UV-LEDs for Radiation Vulcanization of Natural Rubber Latex
Published 2018-01-01“…The UV-LED photoreactor prototype design results show that the UV-LED photoreactor prototype is ready to test the VNRLI process function that can produce NRL- irradiated free carcinogen and protein allergens.…”
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1025
Risk Factors for Breast Cancer, Including Occupational Exposures
Published 2011-03-01“…Ethylene oxide is also classified as a Group 1 carcinogen, although the evidence for carcinogenicity in epidemiologic studies, and specifically for the human breast, is limited. …”
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1026
Crises in Antimicrobial Stewardship: Misuse of Clarithromycin for <i>Helicobacter pylori</i> Therapy
Published 2024-02-01“…<i>Helicobacter pylori</i> is a class I carcinogen that infects more than 100 million individuals in the United States. …”
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1027
Morphological and chemical variations of sweet flag (Acorus calamus L.) in the Czech and Finnish gene bank collection
Published 2007-03-01“…This amount is not sufficient according to the Czech norm for Radix calami quality (minimal amount is 2%) but the content of carcinogen β-asarone, which was established at 9-21% in the essential oil in all the analyzed sweet flags, did not exceed the maximal recommended value 0.5% of dry drug mass.…”
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1028
Fucoxanthin Is a Potential Therapeutic Agent for the Treatment of Breast Cancer
Published 2022-05-01“…Other signaling molecules such as MAPK, MMP2/9, CYP and ROS are also involved in the anti-cancer effects by regulating the tumor microenvironment, cancer metastasis, carcinogen metabolism and oxidation. Besides, Fx also possesses anti-obesity effects by regulating UCP1 levels and lipid metabolism, which may help to reduce BC risk. …”
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1029
REVIEW ON AFLATOXIN IN INDONESIAN FOOD- AND FEEDSTUFFS AND THEIR PRODUCTS
Published 2011-11-01“… Aflatoxin is a human carcinogen that could contaminate food- and feedstuffs, and hence is a major food quality problem throughout the world. …”
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1030
Crosstalk between cancer stem cells and the tumor microenvironment drives progression of premalignant oral epithelium
Published 2023-01-01“…There is mounting evidence that carcinogen-initiated mucosal epithelial stem cells acquire the CSC phenotype following exposure to environmental or infectious mutagens and are responsible for promoting the malignant transformation of premalignant (dysplastic) epithelium. …”
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1031
Can yesterday’s smoking research inform today’s shiftwork research? Epistemological consequences for exposures and doses due to circadian disruption at and off work
Published 2017-09-01“…Abstract In 1950, landmark epidemiology studies by Wynder & Graham and Doll & Hill contributed to identifying smoking as a potent carcinogen. In 2007, IARC classified shiftwork involving circadian disruption (CD) as probably carcinogenic; however, epidemiological evidence in regards to the carcinogenicity of shiftwork that involves nightwork is conflicting. …”
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1032
<i>Helicobacter pylori</i> Biofilm Confers Antibiotic Tolerance in Part via A Protein-Dependent Mechanism
Published 2020-06-01“…<i>Helicobacter pylori</i>, a WHO class I carcinogen, is one of the most successful human pathogens colonizing the stomach of over 4.4 billion of the world’s population. …”
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1033
Melatonin and Cancer: A Polyhedral Network Where the Source Matters
Published 2021-02-01“…In 2007, the World Health Organization classified night shift work as a probable carcinogen due to circadian disruption, where melatonin plays a central role. …”
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1034
Inherited Genetic Mutations and Polymorphisms in Malignant Mesothelioma: A Comprehensive Review
Published 2020-06-01“…Furthermore, we identified several single nucleotide polymorphisms (SNPs) that may promote MM tumorigenesis as a result of an asbestos–gene interaction, including SNPs in DNA repair, carcinogen detoxification and other genes previously associated with other malignancies. …”
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1035
Chemopreventive Effect of <i>Cratoxylum formosum</i> (Jack) ssp. <i>pruniflorum</i> on Initial Stage Hepatocarcinogenesis in Rats
Published 2021-07-01“…This study investigated the effect of CP on early-stage hepatocarcinogenesis in rat liver when using diethylnitrosamine (DEN) as a carcinogen. Immunohistochemistry was used to detect (a) upregulation of glutathione <i>S</i>-transferase placental (GST-P) positive foci, (b) the proliferating cell nuclear antigen PCNA, and (c) apoptotic cells in the liver as indicators of early-stage carcinogenesis. …”
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1036
Bacterial infection and microbiota in carcinogenesis and tumor development
Published 2023-11-01“…Infection of Helicobacter pylori in gastric cancer carcinogenesis is recognized as class I carcinogen by the World Health Organization (WHO) decades ago. …”
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1037
The Cytolethal Distending Toxin Effects on Mammalian Cells: A DNA Damage Perspective
Published 2014-06-01“…In vivo, CDT has been shown to induce the development of dysplastic nodules and to lead to genetic instability, defining CDT as a potential carcinogen. It is therefore important to characterize the outcome of the CDT-induced DNA damage and the consequences for intoxicated cells and organisms. …”
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1038
Occupational Burden of Cancer in Korea
Published 2010-09-01“…Methods: Nine kinds of Group 1 carcinogens addressed by the International Agency for Research on Cancer (IARC) and 7 kinds of cancer were selected for the target carcinogens and diseases, respectively. …”
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1039
Dynamic changes of DNA methylation induced by benzo(a)pyrene in cancer
Published 2023-07-01“…Abstract Benzo(a)pyrene (BaP), the earliest and most significant carcinogen among polycyclic aromatic hydrocarbons (PAHs), has been found in foods, tobacco smoke, and automobiles exhaust, etc. …”
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1040
Analysis of Polycyclic Aromatic Hydrocarbons (PAHs) in Household Dusts of the City of Khorramabad, Iran
Published 2022-12-01“…Individuals spend a lot of time indoors, thus they can generally be exposed to polycyclic aromatic hydrocarbons (PAHs) as a teratogen, mutagen, and carcinogen pollutants with the potential for environmental and also human health risks. …”
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