Esophageal Findings in the Setting of a Novel Preventive Strategy to Avoid Thermal Lesions during Hybrid Thoracoscopic Radiofrequency Ablation for Atrial Fibrillation by Rani Kronenberger, Ines Van Loo, Carlo de Asmundis, Maridi Aerts, Sandro Gelsomino, Vincent Umbrain, Gian-Battista Chierchia, Mark La Meir

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A robust local pulse wave imaging method based on digital image processing techniques by Shuyan Liu, Peilin Li, Yuanhao Tan, Geqi Ding, Bo Peng

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Phenogrouping and risk stratification of patients undergoing cardiac resynchronization therapy upgrade using topological data analysis by Walter Richard Schwertner, Márton Tokodi, Boglárka Veres, Anett Behon, Eperke Dóra Merkel, Richárd Masszi, Luca Kuthi, Ádám Szijártó, Attila Kovács, István Osztheimer, Endre Zima, László Gellér, Máté Vámos, László Sághy, Béla Merkely, Annamária Kosztin, Dávid Becker

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Long-Standing Persistent Atrial Fibrillation Ablation: How Do You Perform? Left and Right Atrial Linear Ablation in Addition to Pulmonary Vein Isolation by Michele Brunelli, Mark Adrian Sammut

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Modulation of sympathetic nervous system by means of renal denervation for treatment of atrial fibrillation by А. Б. Романов, Е. А. Покушалов, Д. А. Заманов, А. Ю. Дмитриев, Н. В. Шильников, Э. Э. Иваницкая, А. В. Пустовойтов

“…The autonomous nervous system plays a key role in modulation of cardiac electrophysiology. Despite a great body of data on the presence of anatomic and functional relations between the nervous system and the heart, there remain a number of questions unanswered. …”
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Toward a broader view of mechanisms of drug cardiotoxicity by Mamoshina, P, Rodriguez, B, Bueno-Orovio, A

“…Numerous drugs have been shown to have the potential to induce lethal arrhythmias by affecting cardiac electrophysiology, which is the focus of current preclinical testing. …”

Automated adjoints of coupled PDE-ODE systems by Farrell, P, Hake, JE, Funke, SW, Rognes, ME

“…We demonstrate the capabilities of the approach on examples from cardiac electrophysiology and mitochondrial swelling.…”

Acidosis in models of cardiac ventricular myocytes by Crampin, E, Smith, N, Langham, A, Clayton, R, Orchard, C

“…The effects of acidosis on cardiac electrophysiology and excitation-contraction coupling have been studied extensively. …”

Stimulus protocol determines the most computationally efficient preconditioner for the bidomain equations. by Bernabeu, M, Pathmanathan, P, Pitt-Francis, J, Kay, D

“…The efficient solution of the bidomain equations is a fundamental tool in the field of cardiac electrophysiology. When choosing a finite element discretization of the coupled system, one has to deal with the solution of a large, highly sparse system of linear equations. …”

Recent developments in using mechanistic cardiac modelling for drug safety evaluation by Mirams, G, Noble, D, Davies, M, Wang, K, Caruso, A, Walz, A, Lave, T, Schuler, F, Singer, T, Polonchuk, L

“…This review compares and contrasts the state-of-the-art tools from empirical to mechanistic models of cardiac electrophysiology, and how they can and should be used in combination with experimental tests for compound decision making.…”

Spatial-Temporal Signals and Clinical Indices in Electrocardiographic Imaging (I): Preprocessing and Bipolar Potentials by Raúl Caulier-Cisterna, Margarita Sanromán-Junquera, Sergio Muñoz-Romero, Manuel Blanco-Velasco, Rebeca Goya-Esteban, Arcadi García-Alberola, José Luis Rojo-Álvarez

“…This unprecedented amount of measured cardiac signals needs to be conditioned and adapted to current knowledge and methods in cardiac electrophysiology in order to maximize its support to the clinical practice. …”
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Identification of a Novel Target Implicated in Chronic Obstructive Sleep Apnea-Related Atrial Fibrillation by Integrative Analysis of Transcriptome and Proteome by Shen J, Liang J, Rejiepu M, Yuan P, Xiang J, Guo Y, Xiaokereti J, Zhang L, Tang B

“…Jun Shen,1,2,* Junqing Liang,1,2,* Manzeremu Rejiepu,1,2,* Ping Yuan,3 Jie Xiang,1,2 Yankai Guo,1,2 Jiasuoer Xiaokereti,1,2 Ling Zhang,1,2 Baopeng Tang1,2 1Xinjiang Key Laboratory of Cardiac Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Cardiac Pacing and Electrophysiology Department, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 3Department of Cardiology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ling Zhang, Xinjiang Key Laboratory of Cardiac Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China, Tel/Fax +86 18690280833, Email ydzhangling@126.com Baopeng Tang, Cardiac Pacing and Electrophysiology Department, The First Affiliated Hospital of Xinjiang Medical University, 137 Liyushan Road, Urumqi, Xinjiang, 830000, People’s Republic of China, Tel/Fax +86 13477301883, Email tangbaopeng1111@163.comObjective: This study aimed to identify a newly identified target involved in atrial fibrillation (AF) linked to chronic obstructive sleep apnea (COSA) through an integrative analysis of transcriptome and proteome.Methods: Fifteen beagle canines were randomly assigned to three groups: control (CON), obstructive sleep apnea (OSA), and OSA with superior left ganglionated plexi ablation (OSA+GP). …”
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Spatial-Temporal Signals and Clinical Indices in Electrocardiographic Imaging (II): Electrogram Clustering and T-Wave Alternans by Raúl Caulier-Cisterna, Manuel Blanco-Velasco, Rebeca Goya-Esteban, Sergio Muñoz-Romero, Margarita Sanromán-Junquera, Arcadi García-Alberola, José Luis Rojo-Álvarez

“…In addition, this work aims to demonstrate the functionality of ECGI for cardiac electrophysiology from a twofold view, namely, through the analysis of the EGM waveforms, and by studying the ventricular repolarization properties. …”
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Neuronal Nav1.8 Channels as a Novel Therapeutic Target of Acute Atrial Fibrillation Prevention by XiaoMeng Chen, LiLei Yu, ShaoBo Shi, Hong Jiang, CongXin Huang, Mayurika Desai, YiGang Li, Hector Barajas‐Martinez, Dan Hu

“…This study aimed to determine the role of Nav1.8 in cardiac electrophysiology in an acute AF model and explore possible therapeutic targets. …”
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Accuracy of cardiac ablation catheter guidance by means of a single equivalent moving dipole inverse algorithm to identify sites of origin of cardiac electrical activation by Lv, Wener, Lee, Kichang, Arai, Tatsuya, Barrett, Conor D, Hasan, Maysun Mazhar, Hayward, Alison M, Marini, Robert P., Barley, Maya E., Galea, Anna, Hirschman, Gordon, Armoundas, Antonis A, Cohen, Richard J.

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Clinical Characteristics, Genetic Findings and Arrhythmic Outcomes of Patients with Catecholaminergic Polymorphic Ventricular Tachycardia from China: A Systematic Review by Justin Leung, Sharen Lee, Jiandong Zhou, Kamalan Jeevaratnam, Ishan Lakhani, Danny Radford, Emma Coakley-Youngs, Levent Pay, Göksel Çinier, Meltem Altinsoy, Amir Hossein Behnoush, Elham Mahmoudi, Paweł T. Matusik, George Bazoukis, Sebastian Garcia-Zamora, Shaoying Zeng, Ziliang Chen, Yunlong Xia, Tong Liu, Gary Tse

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Opportunities and Challenges in Catheter-Based Irreversible Electroporation for Ventricular Tachycardia by Matthew Leonard Repp, Ikeotunye Royal Chinyere

“…The use of catheter-based irreversible electroporation in clinical cardiac laboratories, termed pulsed-field ablation (PFA), is gaining international momentum among cardiac electrophysiology proceduralists for the non-thermal management of both atrial and ventricular tachyrhythmogenic substrates. …”
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The simplified Kirchhoff network model (SKNM): a cell-based reaction–diffusion model of excitable tissue by Karoline Horgmo Jæger, Aslak Tveito

“…The widely-accepted bidomain model serves as the standard in computational cardiac electrophysiology, and under certain anisotropy ratio conditions, it is well known that it can be reduced to the simpler monodomain model. …”
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Long-Standing Persistent Atrial Fibrillation Ablation: How Do You Perform? Left and Right Atrial Linear Ablation in Addition to Pulmonary Vein Isolation by Michele Brunelli, Mark Adrian Sammut

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Editorial: Atrial fibrillation: insights on mechanisms, mapping and catheter ablation by Sergio Conti, Atul Verma, Andrea Natale, Andrea Natale, Andrea Natale, Claudio Tondo

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