Aspirin for Primary and Secondary Prevention of Mortality, Cardiovascular Disease, and Kidney Failure in the Chronic Renal Insufficiency Cohort (CRIC) StudyPlain-Language Summary by Jonathan J. Taliercio, Georges Nakhoul, Ali Mehdi, Wei Yang, Daohang Sha, Jesse D. Schold, Scott Kasner, Matthew Weir, Mohamed Hassanein, Sankar D. Navaneethan, Geetha Krishnan, Radhika Kanthety, Alan S. Go, Rajat Deo, Claudia M. Lora, Bernard G. Jaar, Teresa K. Chen, Jing Chen, Jiang He, Mahboob Rahman, Lawrence J. Appel, MD, MPH, Debbie L. Cohen, MD, Harold I. Feldman, MD, MSCE, James P. Lash, MD, Robert G. Nelson, MD, PhD, MS, Panduranga S. Rao, MD, Vallabh O. Shah, PhD, MS, Mark L. Unruh, MD, MS

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Artificial Intelligence and Healthcare by Harish Rangareddy, Shashidhar Kurpad Nagaraj

“…In machine learning, the device analyses structured data such as raw data of cardiac electrophysiology, diagnostic imaging and genetics. …”
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Signal-averaged electrocardiography as a noninvasive tool for evaluating the ventricular substrate in patients with nonischemic cardiomyopathy: reassessment of an old tool by Dinh Son Ngoc Nguyen, Dinh Son Ngoc Nguyen, Chin-Yu Lin, Chin-Yu Lin, Fa-Po Chung, Fa-Po Chung, Ting-Yung Chang, Ting-Yung Chang, Li-Wei Lo, Li-Wei Lo, Yenn-Jiang Lin, Yenn-Jiang Lin, Shih-Lin Chang, Shih-Lin Chang, Yu-Feng Hu, Yu-Feng Hu, Ta-Chuan Tuan, Ta-Chuan Tuan, Tze-Fan Chao, Tze-Fan Chao, Jo-Nan Liao, Jo-Nan Liao, Ling Kuo, Ling Kuo, Chih-Min Liu, Chih-Min Liu, Shin-Huei Liu, Shin-Huei Liu, Cheng-I Wu, Cheng-I Wu, Ming-Jen Kuo, Guan-Yi Li, Yu-Shan Huang, Shang-Ju Wu, Shang-Ju Wu, Yoon Kee Siow, Yoon Kee Siow, Jose Antonio L. Bautista, Jose Antonio L. Bautista, Dat Tran Cao, Dat Tran Cao, Shih-Ann Chen, Shih-Ann Chen, Shih-Ann Chen, Shih-Ann Chen

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Clinical significance of substrate characteristics and ablation outcomes in patients with atrial fibrillation and significant functional mitral regurgitation by Jose Antonio L. Bautista, Jose Antonio L. Bautista, Chin-Yu Lin, Chin-Yu Lin, Chi-Ting Lu, Li-Wei Lo, Li-Wei Lo, Yenn-Jiang Lin, Yenn-Jiang Lin, Shih-Lin Chang, Shih-Lin Chang, Yu-Feng Hu, Yu-Feng Hu, Fa-Po Chung, Fa-Po Chung, Ta-Chuan Tuan, Ta-Chuan Tuan, Tze-Fan Chao, Tze-Fan Chao, Jo-Nan Liao, Jo-Nan Liao, Ting-Yung Chang, Ting-Yung Chang, Ling Kuo, Ling Kuo, Chih-Min Liu, Chih-Min Liu, Shin-Huei Liu, Shin-Huei Liu, Cheng-I Wu, Cheng-I Wu, Ming-Jen Kuo, Ming-Jen Kuo, Ming-Jen Kuo, Guan-Yi Li, Yu-Shan Huang, Shang-Ju Wu, Shang-Ju Wu, Yoon Kee Siow, Yoon Kee Siow, Ngoc Nguyen Dinh Son, Ngoc Nguyen Dinh Son, Dat Cao Tran, Dat Cao Tran, Shih-Ann Chen, Shih-Ann Chen, Shih-Ann Chen, Shih-Ann Chen

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The burden and management competency of cardiomyopathies in China: a nationwide survey studyResearch in context by Yu Zhang, Minghao Liu, Peijin Li, Likun Ma, Lixue Yin, Yinghua Cui, Kai Huang, Wei Li, Hui Xin, Meixiang Xiang, Cuilian Dai, Mulei Chen, Jinping Feng, Zeqi Zheng, Yawei Xu, Yihan Chen, Xuejun Jiang, Genshan Ma, Ping Yang, Fang Wang, Xinli Li, Wei Jin, Hong Chen, Rutai Hui, Lian Wang, Hongyan Xiao, Liwen Liu, Yubao Zou, Lei Song

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Management of Inherited Arrhythmia Syndromes: A HiRO Consensus Handbook on Process of Care by Mikyla L. Janzen, MSc, Brianna Davies, MSc, Zachary W.M. Laksman, MD, Jason D. Roberts, MD, Shubhayan Sanatani, MD, Christian Steinberg, MD, Rafik Tadros, MD, Julia Cadrin-Tourigny, MD, Ciorsti MacIntyre, MD, Joseph Atallah, MD, Anne Fournier, MD, Martin S. Green, MD, Robert Hamilton, MD, Habib R. Khan, MBBS, PhD, Shane Kimber, MD, Steven White, MD, PhD, Jacqueline Joza, MD, Bhavanesh Makanjee, MD, Erkan Ilhan, MD, David Lee, MD, Simon Hansom, MD, Alexios Hadjis, MD, Laura Arbour, MD, Richard Leather, MD, Colette Seifer, MD, Paul Angaran, MD, Christopher S. Simpson, MD, Jeffrey S. Healey, MD, Martin Gardner, MD, Mario Talajic, MD, Andrew D. Krahn, MD

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Bmal1 knockdown in the left stellate ganglion inhibits neural activity and prevents ventricular arrhythmias after myocardial ischemia by Zhongyang Yu, Zhongyang Yu, Zhongyang Yu, Zhongyang Yu, Zhongyang Yu, Zhongyang Yu, Zhihao Liu, Zhihao Liu, Zhihao Liu, Zhihao Liu, Zhihao Liu, Zhihao Liu, Liying Jiao, Liying Jiao, Liying Jiao, Liying Jiao, Liying Jiao, Liying Jiao, Song Zhang, Song Zhang, Song Zhang, Song Zhang, Song Zhang, Song Zhang, Liqing Nie, Liqing Nie, Liqing Nie, Liqing Nie, Liqing Nie, Liqing Nie, Yueyi Wang, Yueyi Wang, Yueyi Wang, Yueyi Wang, Yueyi Wang, Yueyi Wang, Liping Zhou, Liping Zhou, Liping Zhou, Liping Zhou, Liping Zhou, Liping Zhou, Yuhong Wang, Yuhong Wang, Yuhong Wang, Yuhong Wang, Yuhong Wang, Yuhong Wang, Zhihao Liu, Zhihao Liu, Zhihao Liu, Zhihao Liu, Zhihao Liu, Zhihao Liu, Zihan Liu, Zihan Liu, Zihan Liu, Zihan Liu, Zihan Liu, Zihan Liu, Xiao Xu, Xiao Xu, Xiao Xu, Xiao Xu, Xiao Xu, Xiao Xu, Zeyan Li, Zeyan Li, Zeyan Li, Zeyan Li, Zeyan Li, Zeyan Li, Yuyang Zhou, Yuyang Zhou, Yuyang Zhou, Yuyang Zhou, Yuyang Zhou, Yuyang Zhou, Huixin Zhou, Huixin Zhou, Huixin Zhou, Huixin Zhou, Huixin Zhou, Huixin Zhou, Rui Li, Rui Li, Rui Li, Rui Li, Rui Li, Rui Li, Chen Peng, Chen Peng, Chen Peng, Chen Peng, Chen Peng, Chen Peng, Lilei Yu, Lilei Yu, Lilei Yu, Lilei Yu, Lilei Yu, Lilei Yu, Hong Jiang, Hong Jiang, Hong Jiang, Hong Jiang, Hong Jiang, Hong Jiang

“…Therefore, we aimed to investigate the influence of Bmal1 knockdown in the LSG on its neural activity and cardiac electrophysiology and to explore the mechanisms.Materials and methodsWe used adeno-associated virus (AAV) to knock down Bmal1 in the LSG. …”
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Prognostic impact of acute pulmonary triggers in patients with takotsubo syndrome: new insights from the International Takotsubo Registry by Ken Kato, Victoria L. Cammann, L. Christian Napp, Konrad A. Szawan, Jozef Micek, Sara Dreiding, Rena A. Levinson, Vanya Petkova, Michael Würdinger, Alexandru Patrascu, Rafael Sumalinog, Sebastiano Gili, Christian F. Clarenbach, Malcolm Kohler, Manfred Wischnewsky, Rodolfo Citro, Carmine Vecchione, Eduardo Bossone, Michael Neuhaus, Jennifer Franke, Benjamin Meder, Milosz Jaguszewski, Michel Noutsias, Maike Knorr, Susanne Heiner, Fabrizio D'Ascenzo, Wolfgang Dichtl, Christof Burgdorf, Behrouz Kherad, Carsten Tschöpe, Annahita Sarcon, Jerold Shinbane, Lawrence Rajan, Guido Michels, Roman Pfister, Alessandro Cuneo, Claudius Jacobshagen, Mahir Karakas, Wolfgang Koenig, Alexander Pott, Philippe Meyer, Marco Roffi, Adrian Banning, Mathias Wolfrum, Florim Cuculi, Richard Kobza, Thomas A. Fischer, Tuija Vasankari, K.E. Juhani Airaksinen, Monika Budnik, Rafal Dworakowski, Philip MacCarthy, Christoph Kaiser, Stefan Osswald, Leonarda Galiuto, Christina Chan, Paul Bridgman, Daniel Beug, Clément Delmas, Olivier Lairez, Ekaterina Gilyarova, Alexandra Shilova, Mikhail Gilyarov, Ibrahim El‐Battrawy, Ibrahim Akin, Martin Kozel, Petr Tousek, David E. Winchester, Jan Galuszka, Christian Ukena, Gregor Poglajen, Pedro Carrilho‐Ferreira, Christian Hauck, Carla Paolini, Claudio Bilato, Masanori Sano, Iwao Ishibashi, Masayuki Takahara, Toshiharu Himi, Yoshio Kobayashi, Abhiram Prasad, Charanjit S. Rihal, Kan Liu, P. Christian Schulze, Matteo Bianco, Lucas Jörg, Hans Rickli, Gonçalo Pestana, Thanh H. Nguyen, Michael Böhm, Lars S. Maier, Fausto J. Pinto, Petr Widimský, Stephan B. Felix, Grzegorz Opolski, Ruediger C. Braun‐Dullaeus, Wolfgang Rottbauer, Gerd Hasenfuß, Burkert M. Pieske, Heribert Schunkert, Martin Borggrefe, Holger Thiele, Johann Bauersachs, Hugo A. Katus, John D. Horowitz, Carlo Di Mario, Thomas Münzel, Filippo Crea, Jeroen J. Bax, Thomas F. Lüscher, Frank Ruschitzka, Jelena R. Ghadri, Christian Templin

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Acute effects of smoking on QT dispersion in healthy males by Mohammad Ali Akbarzadeh, Shahrooz Yazdani, Mohamad Esmail Ghaidari, Mohammad Asadpour-Piranfar, Negar Bahrololoumi-Bafruee, Allahyar Golabchi, Amirhossein Azhari

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Cardiomyocyte electrophysiology and its modulation: current views and future prospects by Huang, CL-H, Lei, M

“…The findings contained in these articles translate naturally into recent classifications of cardiac electrophysiological targets and drug actions, thereby encouraging future iterations of experimental cardiac electrophysiological discovery, and testing directed towards clinical management.…”

Cardiac Conduction Velocity, Remodeling and Arrhythmogenesis by Bo Han, Mark L. Trew, Callum M. Zgierski-Johnston

“…Cardiac electrophysiological disorders, in particular arrhythmias, are a key cause of morbidity and mortality throughout the world. …”
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Credibility assessment of patient-specific computational modeling using patient-specific cardiac modeling as an exemplar by Suran Galappaththige, Richard A. Gray, Caroline Mendonca Costa, Steven Niederer, Pras Pathmanathan

“…We achieve this through a detailed analysis of the activities required to evaluate cardiac electrophysiological models, chosen as an exemplar field due to its maturity and the complexity of such models. …”
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Heart-on-a-chip systems with tissue-specific functionalities for physiological, pathological, and pharmacological studies by Bingsong Gu, Kang Han, Hanbo Cao, Xinxin Huang, Xiao Li, Mao Mao, Hui Zhu, Hu Cai, Dichen Li, Jiankang He

“…For another, the development of techniques for real-time monitoring of biophysical and biochemical signals from cardiac microtissues on heart-on-a-chip systems is introduced, incorporating cardiac electrophysiological signals, contractile activity, and biomarkers. …”
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Atrial standstill associated with lamin A/C mutation: A case report by Yujiao Zhang, Yong Zhang, Manyi Ren, Minghua Xue, Chunying Hu, Yinglong Hou, Zhiyuan Li, Haiyan Qu, Paulo Moreira

“…Unexpectedly, multiple arterial embolization in the patient was due to atrial standstill by transthoracic echocardiography and cardiac electrophysiological study. An additional family investigation revealed that the patient’s brother and sister also suffered from this disease. …”
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Cardiac Rhythm Monitoring Using Wearables for Clinical Guidance before and after Catheter Ablation by Henrike Aenne Katrin Hillmann, Samira Soltani, Johanna Mueller-Leisse, Stephan Hohmann, David Duncker

“…This review aims to describe and to elaborate a potential workflow for the role of wearables for cardiac rhythm monitoring regarding detection and management of arrhythmias before and after cardiac electrophysiological procedures.…”
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Estimation of Activation Times in Cardiac Tissue Using Graph Based Methods by Wallman, M, Smith, N, Rodriguez, B

“…The bidomain and monodomain equations are well established as the standard set of equations for the simulation of cardiac electrophysiological behaviour. However, the computational cost of detailed bidomain/monodomain simulations limits their applicability to scenarios in which results are needed in real time (e.g. clinical scenarios). …”

Modeling cardiac ischemia. by Rodríguez, B, Trayanova, N, Noble, D

“…Over the last decade, computer simulations have demonstrated the ability to provide insight, with high spatiotemporal resolution, into ischemic abnormalities in cardiac electrophysiological behavior from the ionic channel to the whole organ. …”

Electrocardiographic Patch Devices and Contemporary Wireless Cardiac Monitoring by Erik eFung, Erik eFung, Erik eFung, Erik eFung, Marjo-Riitta eJärvelin, Marjo-Riitta eJärvelin, Marjo-Riitta eJärvelin, Marjo-Riitta eJärvelin, Rahul N Doshi, Jerold S Shinbane, Steven K Carlson, Luanda P Grazette, Philip M Chang, Philip M Chang, Rajbir S Sangha, Rajbir S Sangha, Heikki Veli Huikuri, Nicholas S Peters, Nicholas S Peters

“…Cardiac electrophysiologic derangements often coexist with disorders of the circulatory system. …”
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Targeting p21-activated kinase 1 for development of a novel anti-arrhythmic drug class. by He, Y, Grassam-Rowe, A, Lei, M, Bae, JSH

“…The present article provides an updated review of recent findings regarding the role of PAK1 in maintaining normal cardiac electrophysiological function through its regulation of membrane and Ca2+ clocks. …”

Electrocardiographic Alterations in Patients with Common Variable Immune Deficiency by Yakup Alsancak, Fatih Çölkesen

“…In addition, the QT interval and corrected QT interval, T peak-to-end interval were higher in the CVID arm, and the index of cardiac electrophysiological balance value obtained with the QT/QRS ratio was also higher in the CVID group. …”
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