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Post-Transcriptional Regulation of Molecular Determinants during Cardiogenesis
Published 2022-03-01Get full text
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Geterogenety walls of heart on stages of early human cardiogenesis.
Published 2007-01-01Subjects: “…cardiogenesis…”
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Ultrastructural characteristics of mitochondria in rat cardiomyocytes in the early cardiogenesis.
Published 2012-01-01Subjects: Get full text
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Desmosomes in Cell Fate Determination: From Cardiogenesis to Cardiomyopathy
Published 2023-08-01Subjects: Get full text
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Understanding Epicardial Cell Heterogeneity during Cardiogenesis and Heart Regeneration
Published 2023-09-01“…Despite its quiescent state during adulthood, the adult epicardium reactivates and recapitulates many aspects of embryonic cardiogenesis in response to cardiac injury, thereby supporting cardiac tissue remodeling. …”
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Distinct myocardial lineages break atrial symmetry during cardiogenesis in zebrafish
Published 2018-05-01Get full text
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Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling
Published 2023-07-01“…Furthermore, genetic and pharmacological normalization of IFN signaling restored canonical WNT signaling and rescued defects in cardiogenesis in DS in vitro and in vivo. Our findings provide insights into mechanisms underlying abnormal cardiogenesis in DS, ultimately aiding the development of therapeutic strategies.…”
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Wnt2 is a direct downstream target of GATA6 during early cardiogenesis.
Published 2006“…However, little is known of the immediate downstream targets of GATA-factor regulation during the earliest stages of cardiogenesis. Using the P19-CL6 embryonal carcinoma (EC) cell line as an in vitro model of cardiogenesis, we show that GATA6 is the most abundantly expressed of the GATA factors in presumptive cardiac cells. …”
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GATA factors lie upstream of Nkx 2.5 in the transcriptional regulatory cascade that effects cardiogenesis.
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An EGFP Knock-in Zebrafish Experimental Model Used in Evaluation of the Amantadine Drug Safety During Early Cardiogenesis
Published 2022-04-01“…Specifically, this study identified teratogenic effects of amantadine drug during early cardiogenesis dose dependent, which could be likely conveyed by inhibiting expression of key genes required for cardiac myocardium differentiation and LR asymmetry.…”
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Efectos de la obesidad materna sobre el patrón de apoptosis en la cardiogénesis tardía
Published 2018-01-01Subjects: Get full text
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Dynamic BAF chromatin remodeling complex subunit inclusion promotes temporally distinct gene expression programs in cardiogenesis
Published 2019“…Thus, dynamic interdependent BAF complex subunit assembly modulates chromatin states and thereby participates in directing temporal gene expression programs in cardiogenesis.…”
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Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis.
Published 2010-01-01“…CONCLUSIONS/SIGNIFICANCE: Our results suggest an essential role for IP3Rs in cardiogenesis in part through the regulation of calcineurin-NFAT signaling.…”
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Hyaluronan esters drive Smad gene expression and signaling enhancing cardiogenesis in mouse embryonic and human mesenchymal stem cells.
Published 2010-01-01“…Smad4 silencing by the aid of lentiviral-mediated Smad4 shRNA confirmed a dominant role of Smad4 in HBR-induced cardiogenesis. CONCLUSIONS/SIGNIFICANCE: The use of HBR may pave the way to novel combinatorial strategies of molecular and stem cell therapy based on fine tuning of targeted Smad transciption and signaling leading to a high-throughput of cardiogenesis without the needs of gene transfer technologies.…”
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MODERN VIEWS ON THE GENE NOTCH1 MUTATIONS ROLE FOR AORTIC COARCTATION
Published 2014-10-01Subjects: Get full text
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NKX2-5 mutations causative for congenital heart disease retain functionality and are directed to hundreds of targets
Published 2015-07-01Subjects: “…cardiogenesis…”
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MORPHOMETRY OF MYOFIBRILES AND CONCLUSIVE APPARATUS IN THE PERIOD OF POSTPATAL MATURATION OF CARDIOMYOCYTES
Published 2022-03-01Subjects: “…cardiogenesis…”
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Morphological features of atrial myocardium embryonic development and its changes caused by hypoxia effect
Published 2019-03-01Subjects: “…cardiogenesis; atria; ultrastructure of cardiomyocytes; rats.…”
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