Showing 1 - 20 results of 138 for search '"cardiogenesis"', query time: 0.16s Refine Results
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    Understanding Epicardial Cell Heterogeneity during Cardiogenesis and Heart Regeneration by Cristina Sanchez-Fernandez, Lara Rodriguez-Outeiriño, Lidia Matias-Valiente, Felicitas Ramírez de Acuña, Diego Franco, Amelia Eva Aránega

    Published 2023-09-01
    “…Despite its quiescent state during adulthood, the adult epicardium reactivates and recapitulates many aspects of embryonic cardiogenesis in response to cardiac injury, thereby supporting cardiac tissue remodeling. …”
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    Article
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    Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling by Congwu Chi, Walter E. Knight, Andrew S. Riching, Zhen Zhang, Roubina Tatavosian, Yonghua Zhuang, Radu Moldovan, Angela L. Rachubinski, Dexiang Gao, Hongyan Xu, Joaquin M. Espinosa, Kunhua Song

    Published 2023-07-01
    “…Furthermore, genetic and pharmacological normalization of IFN signaling restored canonical WNT signaling and rescued defects in cardiogenesis in DS in vitro and in vivo. Our findings provide insights into mechanisms underlying abnormal cardiogenesis in DS, ultimately aiding the development of therapeutic strategies.…”
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    Article
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    Wnt2 is a direct downstream target of GATA6 during early cardiogenesis. by Alexandrovich, A, Arno, M, Patient, R, Shah, A, Pizzey, J, Brewer, A

    Published 2006
    “…However, little is known of the immediate downstream targets of GATA-factor regulation during the earliest stages of cardiogenesis. Using the P19-CL6 embryonal carcinoma (EC) cell line as an in vitro model of cardiogenesis, we show that GATA6 is the most abundantly expressed of the GATA factors in presumptive cardiac cells. …”
    Journal article
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    An EGFP Knock-in Zebrafish Experimental Model Used in Evaluation of the Amantadine Drug Safety During Early Cardiogenesis by Shi Ouyang, Shi Ouyang, Wu-Ming Qin, Wu-Ming Qin, Yu-Juan Niu, Yu-Juan Niu, Yong-He Ding, Yong-He Ding, Yun Deng, Yun Deng

    Published 2022-04-01
    “…Specifically, this study identified teratogenic effects of amantadine drug during early cardiogenesis dose dependent, which could be likely conveyed by inhibiting expression of key genes required for cardiac myocardium differentiation and LR asymmetry.…”
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    Dynamic BAF chromatin remodeling complex subunit inclusion promotes temporally distinct gene expression programs in cardiogenesis by Hota, SK, Johnson, JR, Verschueren, E, Thomas, R, Blotnick, AM, Zhu, Y, Sun, X, Pennacchio, LA, Krogan, NJ, Bruneau, BG

    Published 2019
    “…Thus, dynamic interdependent BAF complex subunit assembly modulates chromatin states and thereby participates in directing temporal gene expression programs in cardiogenesis.…”
    Journal article
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    Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis. by Keiko Uchida, Megumi Aramaki, Maki Nakazawa, Chihiro Yamagishi, Shinji Makino, Keiichi Fukuda, Takeshi Nakamura, Takao Takahashi, Katsuhiko Mikoshiba, Hiroyuki Yamagishi

    Published 2010-01-01
    “…CONCLUSIONS/SIGNIFICANCE: Our results suggest an essential role for IP3Rs in cardiogenesis in part through the regulation of calcineurin-NFAT signaling.…”
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    Hyaluronan esters drive Smad gene expression and signaling enhancing cardiogenesis in mouse embryonic and human mesenchymal stem cells. by Margherita Maioli, Sara Santaniello, Andrea Montella, Pasquale Bandiera, Silvia Cantoni, Claudia Cavallini, Francesca Bianchi, Vincenzo Lionetti, Flavio Rizzolio, Irene Marchesi, Luigi Bagella, Carlo Ventura

    Published 2010-01-01
    “…Smad4 silencing by the aid of lentiviral-mediated Smad4 shRNA confirmed a dominant role of Smad4 in HBR-induced cardiogenesis. CONCLUSIONS/SIGNIFICANCE: The use of HBR may pave the way to novel combinatorial strategies of molecular and stem cell therapy based on fine tuning of targeted Smad transciption and signaling leading to a high-throughput of cardiogenesis without the needs of gene transfer technologies.…”
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    Morphological features of atrial myocardium embryonic development and its changes caused by hypoxia effect by K. M. Shevchenko

    Published 2019-03-01
    Subjects: “…cardiogenesis; atria; ultrastructure of cardiomyocytes; rats.…”
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    Article