Modulation of Trans-Synaptic Neurexin–Neuroligin Interaction in Pathological Pain by Huili Li, Ruijuan Guo, Yun Guan, Junfa Li, Yun Wang

“…The structural and functional characteristics of synapses are highly dynamic, exhibiting extensive plasticity that is shaped by neural activity and regulated primarily by trans-synaptic cell-adhesion molecules (CAMs). Prototypical trans-synaptic CAMs, such as neurexins (Nrxs) and neuroligins (Nlgs), directly regulate the assembly of presynaptic and postsynaptic molecules, including synaptic vesicles, active zone proteins, and receptors. …”
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Distinct roles for extracellular and intracellular domains in neuroligin function at inhibitory synapses by Quynh-Anh Nguyen, Meryl E Horn, Roger A Nicoll

“…Neuroligins (NLGNs) are postsynaptic cell adhesion molecules that interact trans-synaptically with neurexins to mediate synapse development and function. …”
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The activation of dormant ependymal cells following spinal cord injury by Francisco Javier Rodriguez-Jimenez, Pavla Jendelova, Slaven Erceg

“…We review our current understanding of the signaling pathways and molecular events that mediate the SCI-induced activation of ependymal cells by focusing on the roles of some cell adhesion molecules, cellular membrane receptors, ion channels (and their crosstalk), and transcription factors. …”
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Micro-PET Imaging of αβ-Integrin Expression with F-Labeled Dimeric RGD Peptide by Xiaoyuan Chen, Michel Tohme, Ryan Park, Yingping Hou, James R. Bading, Peter S. Conti

“…The α v integrins, which act as cell adhesion molecules, are closely involved with tumor invasion and angiogenesis. …”
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Genetic atlas of hygro-and thermosensory cells in the vinegar fly Drosophila melanogaster by Kristina Corthals, Vilma Andersson, Allison Churcher, Johan Reimegård, Anders Enjin

“…We found that each cell type could be characterized by a unique expression profile of ion channels, GPCR signaling molecules, synaptic vesicle cycle proteins, and cell adhesion molecules. Our findings provide valuable insights into the molecular basis of hygro- and thermosensation. …”
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A quest for genetic causes underlying signaling pathways associated with neural tube defects by Sunil Rai, Larissa Leydier, Shivani Sharma, Jigar Katwala, Anurag Sahu

“…Additionally, we also shine a light on the role of folate and cell adhesion molecules (CAMs) in neural tube defects.…”
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The Regulatory Roles of Cerebellar Glycosphingolipid Microdomains/Lipid Rafts by Keisuke Komatsuya, Norihito Kikuchi, Tetsuya Hirabayashi, Kohji Kasahara

“…Furthermore, the functional roles of cerebellar raft-binding proteins including cell adhesion molecule L1, heterotrimeric G protein Gsα, and L-type voltage-dependent calcium channels are discussed.…”
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Mechanistic Pathogenesis of Endothelial Dysfunction in Diabetic Nephropathy and Retinopathy by Jing Yang, Jing Yang, Jing Yang, Jing Yang, Zhangsuo Liu, Zhangsuo Liu, Zhangsuo Liu, Zhangsuo Liu

“…In addition, DN and DR diseases development are involved in several critical regulators including the cell adhesion molecules (CAMs), the vascular endothelial growth factor (VEGF) family and the Notch signal. …”
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Adhesion Deregulation in Acute Myeloid Leukaemia by Alicja M. Gruszka, Debora Valli, Cecilia Restelli, Myriam Alcalay

“…Cell adhesion is a process through which cells interact with and attach to neighboring cells or matrix using specialized surface cell adhesion molecules (AMs). Adhesion plays an important role in normal haematopoiesis and in acute myeloid leukaemia (AML). …”
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Intratumoral lymphatics are essential for the metastatic spread and prognosis in squamous cell carcinomas of the head and neck region. by Maula, S, Luukkaa, M, Grénman, R, Jackson, D, Jalkanen, S, Ristamäki, R

“…To investigate the possible mechanisms involved, we studied the expression of cancer cell adhesion molecules together with lymphatic vascular and blood vascular markers in a panel of 97 primary HNSCC tumors and correlated expression levels with conventional clinicopathological parameters and with long-term prognosis. …”

Molecular and cellular effects of hydrogen peroxide on human lung cancer cells: potential therapeutic implications by Vilema-Enríquez, MG, Arroyo, A, Grijalva, M, Amador-Zafra, RI, Camacho, J

“…H2O2 produces both nuclear and mitochondrial DNA lesions, increases the expression of cell adhesion molecules, and increases p53 activity and other transcription factors orchestrating cancer cell death. …”

Blocking development of a CD8+ T cell response by targeting lymphatic recruitment of APC. by Teoh, D, Johnson, L, Hanke, T, Mcmichael, A, Jackson, D

“…In this study, we have explored such possibilities using an F(5) TCR-transgenic mouse model to assess the contribution of lymphatic cell adhesion molecules in the CD8(+) T cell response to influenza virus nucleoprotein (NP). …”

Association study of endometriosis and intercellular adhesion molecule-1 (ICAM-1) gene polymorphisms in a Japanese population. by Yamashita, M, Yoshida, S, Kennedy, S, Ohara, N, Motoyama, S, Maruo, T

“… OBJECTIVE: Endometriosis is an immune-related, chronic inflammatory disease with polygenic predisposition. Cell adhesion molecules are expressed in endometriotic lesions, and in cells and tissues that are involved in the development and progression of the disease. …”

The NH2-terminal domain of rat CD2 binds rat CD48 with a low affinity and binding does not require glycosylation of CD2. by van der Merwe, P, McPherson, D, Brown, M, Barclay, A, Cyster, J, Williams, A, Davis, S

“…CD2, CD48 and CD58 are structurally similar cell adhesion-molecules forming a subset of the immunoglobulin superfamily (IgSF). …”

An integrated study of glutamine alleviates enteritis induced by glycinin in hybrid groupers using transcriptomics, proteomics and microRNA analyses by Yuanfa He, Yuanfa He, Xiaohui Dong, Xiaohui Dong, Qihui Yang, Qihui Yang, Hongyu Liu, Hongyu Liu, Shuang Zhang, Shuang Zhang, Shiwei Xie, Shiwei Xie, Shuyan Chi, Shuyan Chi, Beiping Tan, Beiping Tan

“…In conclusion, ECM-receptor interaction, tight junction, and cell adhesion molecules pathways play a key role in glutamine alleviation of hybrid grouper enteritis induced by high-dose glycinin, in which miRNAs and target mRNAs/proteins participated cooperatively. …”
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Adipocytes Promote Early Steps of Breast Cancer Cell Dissemination via Interleukin-8 by Gabriela Vazquez Rodriguez, Gabriela Vazquez Rodriguez, Annelie Abrahamsson, Annelie Abrahamsson, Lasse Dahl Ejby Jensen, Charlotta Dabrosin, Charlotta Dabrosin

“…Mechanistically, overexpression of cell-adhesion molecules in BCC and neutrophils via IL-8 increased the dissemination of BCC. …”
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Identification and comparative analysis of the protocadherin cluster in a reptile, the green anole lizard. by Xiao-Juan Jiang, Shaobing Li, Vydianathan Ravi, Byrappa Venkatesh, Wei-Ping Yu

“…BACKGROUND:The vertebrate protocadherins are a subfamily of cell adhesion molecules that are predominantly expressed in the nervous system and are believed to play an important role in establishing the complex neural network during animal development. …”
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Synapse maintenance and restoration in the retina by NGL2 by Florentina Soto, Lei Zhao, Daniel Kerschensteiner

“…Synaptic cell adhesion molecules (CAMs) promote synapse formation in the developing nervous system. …”
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Cornering metastases: therapeutic targeting of circulating tumor cells and stem cells. by Bishoy eFaltas

“…Selectin-coated tubes that target cell adhesion molecules, immuno-magnetic separators and in-vivo photoacoustic flow cytometers are currently being developed for this purpose. …”
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Cancer-Associated Angiogenesis: The Endothelial Cell as a Checkpoint for Immunological Patrolling by Antonio Giovanni Solimando, Simona De Summa, Angelo Vacca, Domenico Ribatti

“…This is achieved, in part, via the directed chemokines’ expression and cell adhesion molecules on the endothelial cell surface that attract and retain circulating leukocytes. …”
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