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521
Integrated Bioinformatics Analysis to Screen Hub Gene Signatures for Fetal Growth Restriction
Published 2023-01-01“…Single-gene GSEA results showed that all three core genes activated “hematopoietic cell lineage” and “cell adhesion molecules” and inhibited the “cGMP-PKG signaling pathway” in the development of FGR. …”
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522
Exploring shared pathways and the shared biomarker ERRFI1 in Obstructive sleep apnoea and atherosclerosis using integrated bioinformatics analysis
Published 2023-09-01“…Changes in immune pathways, inflammatory processes, and cell adhesion molecules may underlie the pathogenesis of both diseases, and ERRFI1 may be a potential diagnostic marker for patients with OSA and AS.…”
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523
Role of Delta/Notch-like EGF-related receptor in blood glucose homeostasis
Published 2023-05-01“…Contact-dependent interactions between β-cells are mediated by gap junctions and cell adhesion molecules such as E-cadherin and N-CAM. Recent genome-wide studies have implicated Delta/Notch-like EGF-related receptor (Dner) as a potential susceptibility locus for Type 2 Diabetes in humans. …”
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524
PCF11, a Novel CD44-Downstream Transcriptional Target, Linking Its 3’-End Polyadenylation Function to Tumor Cell Metastasis
Published 2022-06-01“…Tumor cell invasion requires cell adhesion molecules (CAMs), and alterations in CAMs is considered as an initiating event in metastasis. …”
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525
Retinal astrocytes transcriptome reveals Cyp1b1 regulates the expression of genes involved in cell adhesion and migration.
Published 2020-01-01“…These genes included those of axon guidance, extracellular matrix proteins and their receptors, cancer, cell adhesion molecules, TGF-β signaling, and the focal adhesion modulation. …”
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526
Identification of RFX5 as prognostic biomarker and associated with immune infiltration in stomach adenocarcinoma
Published 2022-08-01“…Functional enrichment analysis revealed that RFX5 and its related genes were mainly involved in T cell activation, antigen receptor-mediated signaling pathway, cell adhesion molecules, and Th17 cell differentiation. Validation study further verified the expression and prognosis of RFX5 in STAD. …”
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527
CEACAM expression in an in-vitro prostatitis model
Published 2023-08-01“…Carcinoembryogenic antigen-related cell adhesion molecules (CEACAMs) are deregulated in inflammation and in PCa. …”
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528
Size Matters: The Functional Role of the CEACAM1 Isoform Signature and Its Impact for NK Cell-Mediated Killing in Melanoma
Published 2019-03-01“…Various types of cell adhesion molecules have been implicated in tumor progression in melanoma. …”
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529
Polysialylation in a DISC1 Mutant Mouse
Published 2022-05-01“…Polysialylation represents a unique posttranslational modification of a protein, and such changes in neural cell adhesion molecules (NCAMs) have been reported in postmortem brains from patients with psychiatric disorders. …”
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530
Regulation and functions of integrin α2 in cell adhesion and disease
Published 2019-03-01“…Integrins are cell adhesion molecules that are composed of an alpha (α) subunit and a beta (β) subunit with affinity for different extracellular membrane components. …”
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531
The Functional Crosstalk between Myeloid-Derived Suppressor Cells and Regulatory T Cells within the Immunosuppressive Tumor Microenvironment
Published 2021-01-01“…This review aims to outline the current knowledge on the crosstalk between these two cell populations, issuing particularly the potential role of cell adhesion molecules. In this regard, we further discuss the relevance of β2 integrins, which are essential for the differentiation and function of leukocytes as well as for MDSC–Treg interaction. …”
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532
Effect of glycosoaminoglycans on the clinical course of diabetic nephropathy at the stage of microalbuminuria in patients with type 2 diabetes mellitus
Published 2010-06-01“…A total of 30 patients with DM2 and MAU were examined 15 of whom were given sulodexide (200 mg daily) for 6 months.The following parameters were measured before, 3 and 6 months after the onset of therapy: HbA1c level, biochemical characteristics, highly sensitiveCRB, MAU in morning urine samples, soluble intercellular and vascular cell adhesion molecules-1, blood coagulation and anticoagulation factors(PTI, fibrinogen, thrombin time, coagulation factors VII, VIII, X, Willebrand factor), tissue plasminogen activator, and its inhibitor. …”
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533
DIFFERENTIAL LEVELS OF CYTOKINES AND INTERCELLULAR ADHESION MOLECULES AND THEIR DIAGNOSTIC EFFICIENCY IN AUTOIMMUNE AND ONCOLOGICAL THYROID DISEASES
Published 2014-07-01“…The article presents novel data concerning measurements of cytokine levels (IFNγ, IL-4, IL-6, IL-10, TNFβ, MCP-1), and cell adhesion molecules (sE-Selectin, sICAM-1) in blood plasma, llike as parameters of their diagnostic efficiency in the patients with thyroid autoimmune diseases (TAD), thyroid adenoma and cancer. …”
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534
pH-Channeling in Cancer: How pH-Dependence of Cation Channels Shapes Cancer Pathophysiology
Published 2020-09-01“…The cell membrane and integral membrane proteins commonly act as important sensors and transducers of altered pH. Cell adhesion molecules and cation channels are prominent membrane proteins, the majority of which is regulated by protons. …”
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535
Protocadherin 11X/Y a human-specific gene pair: an immunohistochemical survey of fetal and adult brains
Published 2013“…<p>Protocadherins 11X and 11Y are cell adhesion molecules of the δ1-protocadherin family. Pcdh11X is present throughout the mammalian radiation; however, 6 million years ago (MYA), a reduplicative translocation of the Xq21.3 block onto what is now human Yp11 created the <em>Homo sapiens</em>-specific PCDH11Y. …”
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536
Intravascular haemolysis in severe Plasmodium knowlesi malaria: association with endothelial activation, microvascular dysfunction, and acute kidney injury
Published 2018“…As with angiopoietin-2, osteoprotegerin was increased in proportion to disease severity, and independently associated with severity markers including creatinine, lactate, interleukin-6, endothelial cell adhesion molecules ICAM-1 and E-selectin, and impaired microvascular reactivity. …”
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537
Localization of the putative sialic acid-binding site on the immunoglobulin superfamily cell-surface molecule CD22.
Published 1996“…Our results provide further evidence that immunoglobulin superfamily cell adhesion molecules use the GFCC'C" beta-sheet of membrane-distal V-set domains to bind structurally diverse ligands, suggesting that this surface is favored for cell-cell recognition.…”
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538
Prefrontal Cortex Response to Prenatal Insult and Postnatal Opioid Exposure
Published 2022-07-01“…Gene networks that integrate gene connectivity and expression profiles displayed the impact of morphine-by-MIA interaction effects on the pathways. The cell adhesion molecules and long-term depression networks presented an antagonistic effect between morphine and MIA. …”
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539
ADHESION MOLECULES IN INTESTINAL DESTRUCTIVE-INFLAMMATORY PROCESS IN THE CHILDREN WITH ULCERATIVE COLITIS
Published 2013-07-01“…Aim: to study the content of serum soluble cell adhesion molecules in children with ulcerative colitis that mediate the initial and final stages of the migration of leukocytes to the focus of inflammation: sP-selectin (soluble platelet selectin) and Specam-1 (soluble platelet-endothelial cell adhesion molecule 1) as well some earlier unexplored factors associated with their level. …”
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540
Identification of diagnostic biomarkers for osteoarthritis through bioinformatics and machine learning
Published 2024-03-01“…Gene set enrichment analysis revealed that in the OA group, signaling pathways such as AMPK, B cell receptor, IL-17, and PPAR were downregulated, while calcium signaling pathway, cell adhesion molecules, ECM-receptor interaction, TGF-β signaling pathway, and Wnt signaling pathway were upregulated. …”
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