Amelogenesis Imperfecta; Genes, Proteins, and Pathways. by Smith, C, Poulter, J, Antanaviciute, A, Kirkham, J, Brookes, S, Inglehearn, C, Mighell, A

“…Some of the encoded proteins have well documented roles in amelogenesis, acting as enamel matrix proteins or the proteases that degrade them, cell adhesion molecules or regulators of calcium homeostasis. …”

Targeting the VLA-4/VCAM-1 interaction for the diagnosis and prevention of brain metastases by Cheng, V

“…The late stage of diagnosis and the difficulty in defining the tumour boundary both contribute to the lethality of brain metastases. Cell adhesion molecules (CAMs), such as very late antigen-4 (VLA-4) and its ligand vascular cell adhesion molecule-1 (VCAM-1), have been implicated in the metastatic process. …”

Magnetic resonance imaging of endothelial adhesion molecules in mouse atherosclerosis using dual-targeted microparticles of iron oxide. by McAteer, M, Schneider, J, Ali, Z, Warrick, N, Bursill, C, von zur Muhlen, C, Greaves, D, Neubauer, S, Channon, K, Choudhury, R

“…We hypothesized that antibody-conjugated MPIO would enable magnetic resonance imaging (MRI) of endothelial cell adhesion molecules in mouse atherosclerosis. METHODS AND RESULTS: MPIO (4.5 microm) were conjugated to monoclonal antibodies against vascular cell adhesion molecule-1 (VCAM-MPIO) or P-selectin (P-selectin-MPIO). …”

Transcriptional profiling of mycobacterial antigen-induced responses in infants vaccinated with BCG at birth by Fletcher, H, Keyser, A, Bowmaker, M, Sayles, P, Kaplan, G, Hussey, G, Hill, A, Hanekom, W

“…Further analysis revealed a decrease in the expression of cell adhesion molecules (CAMs), including integrin alpha M (ITGAM), which is known to be important for entry of mycobacteria into the macrophage. …”

Nodal-paranodal antibodies in HIV-immune mediated radiculo-neuropathies: clinical phenotypes and relevance by Moodley, K, Patel, VB, Moodley, AA, Bill, PLA, Kajee, A, Mgbachi, V, Fehmi, J, Rinaldi, S

“…</p> <p><strong>Methods:</strong> HIV-infected patients who met the inclusion criteria for chronic IMRN were screened for immunoglobulin G (IgG) antibodies directed against nodal (neurofascin (NF)186) and paranodal (NF155, contactin-1 (CNTN1) and contactin-associated protein(Caspr1)) cell adhesion molecules, using a live, cell-based assay.</p> <p>To explore potential pathogenicity, binding of human IgG to myelinated co-cultures was assessed by incubation with patients' sera positive for nodal or paranodal antibodies. …”

ZNF185 is a p63 target gene critical for epidermal differentiation and squamous cell carcinoma development by Smirnov, A, Lena, A, Cappello, A, Panatta, E, Anemona, L, Bischetti, S, Annicchiarico-Petruzzelli, M, Mauriello, A, Melino, G, Candi, E

“…However, limited knowledge exists on the relevant cell–cell adhesion molecules involved in physiological epithelial formation. …”

Angiogenesis in human cancer by Fox, S

“…To investigate further ECtumour matrix interactions, the expression of cell adhesion molecules (CAMs) was examined. CAM expression mirrored that of EC proliferation with preferential expression on endothelium at the tumour periphery: expression of CAMs was also present on neoplastic cells. …”

Relationship between duration of brain death and hemodynamic (in)stability on progressive dysfunction and increased immunologic activation of donor kidneys. by van der Hoeven, J, Molema, G, Ter Horst, G, Freund, R, Wiersema, J, van Schilfgaarde, R, Leuvenink, H, Ploeg, R

“…Expression of cell adhesion molecules [intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1)] and the influx of leukocytes in the kidney assessed the immunologic status of the kidney. …”

Phenotypic screen of sixty-eight colorectal cancer cell lines identifies CEACAM6 and CEACAM5 as markers of acid-resistance by Michl, J, White, B, Monterisi, S, Bodmer, W, Swietach, P

“…Strikingly, acid resistance was associated with the expression of CEACAM6 and CEACAM5 genes coding for two related cell-adhesion molecules, and among pH-regulating genes, of CA12. …”

Donor brain death aggravates chronic rejection after lung transplantation in rats. by Zweers, N, Petersen, A, van der Hoeven, J, de Haan, A, Ploeg, R, de Leij, L, Prop, J

“…RESULTS: After 6 hr of brain death, influx of polymorphonuclear cells and macrophages and expression of vascular cell adhesion molecule-1 in the donor lungs was increased. …”

The evolving role of nucleotide-binding oligomerisation domain-like receptor Pyrin Domain 3 inflammasome activation in vascular endothelial cells: a review by Abas, Razif, Basir, Rusliza, Mohd Thani, Suryati, Salihan, Safuraa, Saat, Azmah, Mohamad Zainal, Nurul Hayati, Mohamad Asri, Siti Fadziyah, Ab Razak, Nur Izah, Mohd Nor, Nurul Huda, Kamaruddin, Nur Aqilah

“…Molecular changes in the expression of chemokines and cell adhesion molecules ensure protective responses against infection and injury. …”

Xeno-free culture of human pluripotent stem cells on oligopeptide-grafted hydrogels with various molecular designs by Chen, Yen-Ming, Chen, Li-Hua, Li, Meng-Pei, Li, Hsing-Fen, Higuchi, Akon, Kumar, S. Suresh, Ling, Qing-Dong, Alarfaj, Abdullah A., Munusamy, Murugan A., Chang, Yung, Benelli, Giovanni, Murugan, Kadarkarai, Umezawa, Akihiro

“…The dual chain and/or joint segment with cell adhesion molecules on the hydrogels facilitated the proliferation and pluripotency of human ES and iPS cells.…”
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<i>TRPC6</i> Deletion Enhances eNOS Expression and Reduces LPS—Induced Acute Lung Injury by Mengyuan Wang, Xingfang Zhang, Juan Guo, Shangze Yang, Fang Yang, Xingjuan Chen

“…RNA sequencing analysis suggested that downregulated cell adhesion molecules in <i>TRPC6^-/-</i> lungs may be responsible for their resistance to LPS—induced injury. …”
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Thymoquinone (TQ) Inhibits Inflammation and Migration of THP-1 Macrophages: Mechanistic Insights into the Prevention of Atherosclerosis Using In-Vitro and In-Silico Analysis by Etimad Huwait, Nouf Al-Gharawi, Maryam A. Al-Ghamdi, Mamdooh Gari, Alexandre Prola, Peter Natesan Pushparaj, Gauthaman Kalamegam

“…Atherosclerosis is an inflammatory disease mediated by interferon (IFN-γ) in concert with cell adhesion molecules and chemokines. Thymoquinone (TQ), a flavonoid derived from <i>Nigella sativa</i>, is reported to have anti-inflammatory, antioxidant, and cardiovascular protective properties. …”
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The Risk Genes for Neuropsychiatric Disorders <i>negr1</i> and <i>opcml</i> Are Expressed throughout Zebrafish Brain Development by Judith Habicher, Ilaria Sanvido, Anja Bühler, Samuele Sartori, Giovanni Piccoli, Matthias Carl

“…The immunoglobulin LAMP/OBCAM/NTM (IgLON) family of cell adhesion molecules comprises five members known for their involvement in establishing neural circuit connectivity, fine-tuning, and maintenance. …”
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Cancer-associated fibroblasts refine the classifications of gastric cancer with distinct prognosis and tumor microenvironment characteristics by Lei Gu, Dan Ding, Cuicui Wei, Donglei Zhou, Donglei Zhou

“…GSEA revealed significant enrichment of cell adhesion molecules, extracellular matrix receptors and focal adhesions in patients at a high risk of CAF.ConclusionThe CAF signature refines the classifications of GC with distinct prognosis and clinicopathological indicators. …”
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In Vitro Analysis of Matched Isolates from Localized and Disseminated Gonococcal Infections Suggests That Opa Expression Impacts Clinical Outcome by Cheng-Tai Wu, Po-Wei Huang, Chia-Hsuan Lin, Daniel C. Stein, Wenxia Song, Sung-Pin Tseng, Liang-Chun Wang

“…The local cervical isolates recruited the host receptors of gonococcal Opa proteins carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) on epithelial cells. However, the transmigrated cervical isolate and the disseminated blood isolates recruit CEACAMs significantly less often. …”
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Cytokine-Mediated Dysregulation of Signaling Pathways in the Pathogenesis of Multiple Myeloma by Sabah Akhtar, Tayyiba A. Ali, Ammara Faiyaz, Omar S. Khan, Syed Shadab Raza, Michal Kulinski, Halima El Omri, Ajaz A. Bhat, Shahab Uddin

“…The interaction of MM cells with the bone marrow (BM) microenvironment through soluble factors and cell adhesion molecules causes pathogenesis of the disease through activation of multiple signaling pathways, including NF-κβ, PI3K/AKT and JAK/STAT. …”
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Antitumor Effect of Poplar Propolis on Human Cutaneous Squamous Cell Carcinoma A431 Cells by Chuang Zhang, Yuanyuan Tian, Ao Yang, Weihua Tan, Xiaoqing Liu, Wenchao Yang

“…The main three activated and suppressed Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were extracellular matrix (ECM)-receptor interaction, amoebiasis, cell adhesion molecules (CAMs), nonalcoholic fatty liver disease (NAFLD), retrograde endocannabinoid signaling, and Alzheimer’s disease. …”
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DC-SIGN Receptor Level in Rheumatoid Arthritis Patients in Baghdad; Serological study by Hayam A. Mohammed, Zahra’a A. Ahmed, Aymen A. Othman Alrawi

“…DC-SIGN are important types of C-type lectin receptors (CLRs), expressed on dendritic cells and macrophages, and have a central role in regulating innate and adaptive immunity, function as pattern recognition receptors, and as cell adhesion molecules. Recent evidence has demonstrated that DC-SIGN is involved in the pathophysiological of chronic inflammation, so DC-SIGN has been linked to several autoimmune and may play an essential indicator in the pathogenesis and progression of RA. …”
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