Effect of statins on inflammation and cardiac function in patients with chronic Chagas disease: A protocol for pathophysiological studies in a multicenter, placebo-controlled, proo... by Carolina Campos-Estrada, Edurne Urarte, Marisol Denegri, Litzi Villalón, Fabiola González-Herrera, Ulrike Kemmerling, Juan D Maya

“…Efficacy will be determined by measuring changes in plasma levels of anti-inflammatory and pro-inflammatory cytokines, soluble cell adhesion molecules, BNP, and cTnT. Also, the resting 12-lead ECG and a 2D-echocardiogram will be obtained to evaluate cardiac function.…”
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Nrf2 Activator PB125^® as a Potential Therapeutic Agent against COVID-19 by Joe M. McCord, Brooks M. Hybertson, Adela Cota-Gomez, Kara P. Geraci, Bifeng Gao

“…These include IL-1-beta, IL-6, TNF-α, the cell adhesion molecules ICAM-1, VCAM-1, and E-selectin, and a group of IFN-γ-induced genes. …”
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The NMR studies of CMP inhibition of polysialylation by Bo Lu, Si-Ming Liao, Xue-Hui Liu, Shi-Jie Liang, Jun Huang, Mei Lin, Li Meng, Qing-Yan Wang, Ri-Bo Huang, Guo-Ping Zhou

“…AbstractThe overexpression of polysialic acid (polySia) on neural cell adhesion molecules (NCAM) promotes hypersialylation, and thus benefits cancer cell migration and invasion. …”
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Single-cell transcriptome profiles of Drosophila fruitless-expressing neurons from both sexes by Colleen M Palmateer, Catherina Artikis, Savannah G Brovero, Benjamin Friedman, Alexis Gresham, Michelle N Arbeitman

“…Marker gene analyses also show that genes that encode members of the immunoglobulin superfamily of cell adhesion molecules, transcription factors, neuropeptides, neuropeptide receptors, and Wnts have unique patterns of enriched expression across the clusters. …”
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Mapping the transcriptional diversity of genetically and anatomically defined cell populations in the mouse brain by Ken Sugino, Erin Clark, Anton Schulmann, Yasuyuki Shima, Lihua Wang, David L Hunt, Bryan M Hooks, Dimitri Tränkner, Jayaram Chandrashekar, Serge Picard, Andrew L Lemire, Nelson Spruston, Adam W Hantman, Sacha B Nelson

“…Long neuronal effector genes, such as channels and cell adhesion molecules, contribute disproportionately to neuronal diversity, based on their patterns rather than robustness of expression differences. …”
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The Blockade of Mitogen-Activated Protein Kinase 14 Activation by Marine Natural Product Crassolide Triggers ICD in Tumor Cells and Stimulates Anti-Tumor Immunity by Keng-Chang Tsai, Chia-Sheng Chen, Jui-Hsin Su, Yu-Ching Lee, Yu-Hwei Tseng, Wen-Chi Wei

“…In this study, we investigated the effects of crassolide on the induction of ICD, the expression of immune checkpoint molecules and cell adhesion molecules, as well as tumor growth in a murine 4T1 mammary carcinoma model. …”
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Sesamol inhibits LPS induced angiogenesis via downregulating VEGFA/VEGFR2 signalling both in vitro and in vivo by Aparna N S, Aswani S S, Mithra S Mohan, Boban P T, Saja Kamalamma

“…Western blot, ELISA and qPCR analysis were carried out to study the expression of proangiogenic factors such as VEGFA, VEGFR2, MMP-9 and cell adhesion molecules. Results: Sesamol downregulated the LPS induced tube formation and cell migration in RAEC. …”
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Exploring Relevant mRNAs and miRNAs in Injured Urethral Tissues of Rats with High-Throughput Sequencing by Han Lin, Shiyong Guo, Song Li, Jihong Shen, Jianfeng He, Yun Zheng, Zhenhua Gao

“…The differentially expressed mRNAs were mainly involved in the positive regulation of epithelial cell differentiation, focal adhesion, cell adhesion molecules, protein activation cascade, complement activation, complement and coagulation cascades, and chemokine-mediated signaling pathway. …”
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Identify differential gene expressions in fatty infiltration process in rotator cuff by Pengfei Hu, Lifeng Jiang, Lidong Wu

“…Significantly enriched KEGG pathways associated with these DEGs included the phagosome, cell adhesion molecules, tuberculosis, and osteoclast differentiation. …”
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Effects of Bovine Colostrum with or without Egg on In Vitro Bacterial-Induced Intestinal Damage with Relevance for SIBO and Infectious Diarrhea by Raymond J. Playford, Naheed Choudhry, Paul Kelly, Tania Marchbank

“…Adding bacteria to monolayers reduced TEER and (with minor variations among species) increased bacterial translocation, increased monolayer apoptosis (increased caspase-3 and Baxα, reduced Bcl2), increased intercellular adhesion molecule 1 (ICAM-1), and reduced cell adhesion molecules zonulin1 (ZO1) and claudin-1. BC, egg, or the combination reduced these effects (all <i>p</i> < 0.01) and caused additional increases in vascular endothelial growth factor (VEGF) and Heat Shock Protein 70 (Hsp70) expression. …”
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Priming a vascular-selective cytokine response permits CD8+ T-cell entry into tumors by Dae Joong Kim, Swetha Anandh, Jamie L. Null, Piotr Przanowski, Sanchita Bhatnagar, Pankaj Kumar, Sarah E. Shelton, Erin E. Grundy, Katherine B. Chiappinelli, Roger D. Kamm, David A. Barbie, Andrew C. Dudley

“…Dnmt1 deletion in endothelial cells (ECs) impairs tumor growth while priming expression of cytokine-driven cell adhesion molecules and chemokines important for CD8+ T-cell trafficking across the vasculature; consequently, the efficacy of immune checkpoint blockade (ICB) is enhanced. …”
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Identification of key differential genes in intimal hyperplasia induced by left carotid artery ligation by Lina Zhang, Jianjun Gu, Sichuan Wang, Fuming He, Kaizheng Gong

“…These DEGs were significantly enriched in biological processes, including immune system process, cell adhesion, and several pathways, which were mainly associated with cell adhesion molecules and the regulation of the actin cytoskeleton. …”
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CD44 Can Compensate for IgSF11 Deficiency by Associating with the Scaffold Protein PSD-95 during Osteoclast Differentiation by Hyunsoo Kim, Noriko Takegahara, Matthew C. Walsh, Yongwon Choi

“…Additional signaling from cell surface receptors, such as cell adhesion molecules (CAMs), is also required for osteoclast maturation. …”
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Evolution of host-microbe cell adherence by receptor domain shuffling by EmilyClare P Baker, Ryan Sayegh, Kristin M Kohler, Wyatt Borman, Claire K Goodfellow, Eden R Brush, Matthew F Barber

“…Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) encompass a multifunctional family of vertebrate cell surface proteins which are recurrent targets of bacterial adhesins at epithelial barriers. …”
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NOG-Derived Peptides Can Restore Neuritogenesis on a CRASH Syndrome Cell Model by Matteo Gasparotto, Yuriko Suemi Hernandez Gomez, Daniele Peterle, Alessandro Grinzato, Federica Zen, Giulia Pontarollo, Laura Acquasaliente, Giorgia Scapin, Elisabetta Bergantino, Vincenzo De Filippis, Francesco Filippini

“…Homo- and heterophilic binding mediated by the immunoglobulin (Ig)-like repeats of cell adhesion molecules play a pivotal role in cell-cell and cell-extracellular matrix interactions. …”
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Single-cell transcriptomics reveals functionally specialized vascular endothelium in brain by Hyun-Woo Jeong, Rodrigo Diéguez-Hurtado, Hendrik Arf, Jian Song, Hongryeol Park, Kai Kruse, Lydia Sorokin, Ralf H Adams

“…Through single-cell RNA sequencing of non-neuronal cell populations of the murine cerebral cortex during development, adulthood, ageing, and neuroinflammation, we identify reactive endothelial venules, a compartment of specialized postcapillary endothelial cells that are characterized by consistent expression of cell adhesion molecules, preferential leukocyte transmigration, association with perivascular macrophage populations, and endothelial activation initiating CNS immune responses. …”
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Therapeutic potential of catechin as an IKK-β inhibitor for the management of arthritis: In vitro and In vivo approach by Gourav Goyal, Harikesh Kalonia, Viney Lather

“…A range of cytokines, cell adhesion molecules, and enzymes that are implicated in the debilitating effects of RA are transcribed by nuclear factor kappa. …”
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LncRNAs regulate the cyclic growth and development of hair follicles in Dorper sheep by Haoran Sun, Ke Meng, Yifan Wang, Yayan Wang, Xiaochun Yuan, Xinhai Li

“…Gene Ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses revealed that the target genes were largely enriched in the Estrogen signaling pathway, PI3K-Akt signaling pathway, Fc gamma R-mediated phagocytosis, and cell adhesion molecules (CAMs), which are associated with hair follicle cyclic growth and development-related pathways. …”
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Autism and Intellectual Disability-Associated KIRREL3 Interacts with Neuronal Proteins MAP1B and MYO16 with Potential Roles in Neurodevelopment. by Ying F Liu, Sarah M Sowell, Yue Luo, Alka Chaubey, Richard S Cameron, Hyung-Goo Kim, Anand K Srivastava

“…Cell-adhesion molecules of the immunoglobulin superfamily play critical roles in brain development, as well as in maintaining synaptic plasticity, the dysfunction of which is known to cause cognitive impairment. …”
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Chromatin accessibility and cell cycle progression are controlled by the HDAC-associated Sin3B protein in murine hematopoietic stem cells by Alexander Calderon, Tamara Mestvirishvili, Francesco Boccalatte, Kelly V. Ruggles, Gregory David

“…Single cell transcriptional profiling of hematopoietic stem and progenitor cells (HSPCs) inactivated for Sin3B reveals aberrant progression through the G1 phase of the cell cycle, which correlates with the engagement of specific signaling pathways, including aberrant expression of cell adhesion molecules and the interferon signaling program in LT-HSCs. …”
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