The isolation of VCAM-1+ endothelial cell-derived extracellular vesicles using microfluidics by Akbar, N, Luciani, EG, Ahmad, R, Lee, D, Veiga, S, Rabe, DC, Stott, SL

“…<p><strong>Background:</strong>&nbsp;Vascular cell adhesion molecule-1 (VCAM-1⁺) endothelial cell-derived extracellular vesicles (EC-EVs) are augmented in cardiovascular disease, where they can signal the deployment of immune cells from the splenic reserve. …”

Application of Proteomics Approaches in the Identification of New Markers and Therapeutic Targets for Breast Cancer by Moh’d Hamadneh, Lama Abdel Qader

“…Tumor rejection antigen (gp96), heat shock protein 90α, nucleosome assembly protein 1-like 1 and opioid-binding cell adhesion molecule precursor were identified and found to be upregulated in breast cancer cell lines when compared to the normal breast cell line. …”
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Regulatory effects of Zishen Yutai Pill on endometrial epithelial response in vitro in immunology microenvironment by Xiaoli Chen, Yanxin Xie, Lin Li, Shumin Chen, Miao Ding, Na Ning, Qiuling Huang, Xiufei Pang, Jiewen Zhou, Dongzi Yang

“…Expression of intercellular cell adhesion molecule-1 (ICAM-1) was determined using Western blotting (WB). …”
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A single dose of exenatide had no effect on blood flow velocity in the middle cerebral artery in elderly healthy volunteers: Randomized, placebo-controlled, double-blind clinical t... by Joakim Ölmestig, Joakim Ölmestig, Ida R. Marlet, Tina Vilsbøll, Tina Vilsbøll, Jørgen Rungby, Jørgen Rungby, Egill Rostrup, Kate L. Lambertsen, Kate L. Lambertsen, Kate L. Lambertsen, Christina Kruuse, Christina Kruuse

“…No differences between exenatide and placebo group were seen regarding VMCA (p = 0.058), systolic ABI (p = 0.71), plethysmography (p = 0.45), tumor necrosis factor (p = 0.33), interleukin-6 (p = 0.11), interleukin-1β (p = 0.34), vascular cell adhesion molecule 1 (p = 0.73), intercellular adhesion molecule 1 (p = 0.74), or E-selectin (p = 0.31). …”
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High Plasma Angiopoietin-2 Levels Predict the Need to Initiate Dialysis within Two Years in Patients with Chronic Kidney Disease by Anna Szymczak, Mariusz Kusztal, Tomasz Gołębiowski, Krzysztof Letachowicz, Anna Goździk, Katarzyna Kościelska-Kasprzak, Andrzej Tukiendorf, Magdalena Krajewska

“…Plasma levels of angiopoietin (Ang)-2, Vascular Endothelial Growth Factor-C (VEGF-C), Vascular Cell Adhesion Molecule-1 (VCAM-1), Copeptin (CPP), beta-trace protein (BTP), brain natriuretic peptide (BNP), and cardiac troponin I (cTnI) were all measured. …”
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The Identification of Large Rearrangements Involving Intron 2 of the <i>CDH1</i> Gene in <i>BRCA1/2</i> Negative and Breast Cancer Susceptibility by Jihenne Ben Aissa-Haj, Hugo Pinheiro, François Cornelis, Molka Sebai, Didier Meseure, Adrien Briaux, Philippe Berteaux, Cedric Lefol, Gaëtan Des Guetz, Martine Trassard, Denise Stevens, François Vialard, Ivan Bieche, Catherine Noguès, Roseline Tang, Carla Oliveira, Dominique Stoppat-Lyonnet, Rosette Lidereau, Etienne Rouleau

“…E-cadherin, a <i>CDH1</i> gene product, is a calcium-dependent cell–cell adhesion molecule playing a critical role in the establishment of epithelial architecture, maintenance of cell polarity, and differentiation. …”
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Immunologic and vascular biomarkers of mortality in critical COVID-19 in a South African cohort by Jane Alexandra Shaw, Maynard Meiring, Candice Snyders, Frans Everson, Lovemore Nyasha Sigwadhi, Veranyay Ngah, Gerard Tromp, Gerard Tromp, Gerard Tromp, Brian Allwood, Coenraad F. N. Koegelenberg, Elvis M. Irusen, Usha Lalla, Nicola Baines, Annalise E. Zemlin, Rajiv T. Erasmus, Zivanai C. Chapanduka, Tandi E. Matsha, Gerhard Walzl, Hans Strijdom, Nelita du Plessis, Alimuddin Zumla, Alimuddin Zumla, Novel Chegou, Stephanus T. Malherbe, Peter S. Nyasulu, Peter S. Nyasulu

“…Procalcitonin (PCT), C-reactive protein, Endothelin-1 and vascular cell adhesion molecule-1 were elevated in those who died.DiscussionThese results show the pattern of dysregulation in critical COVID-19 in a Sub-Saharan African cohort. …”
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Clusterin and Related Scoring Index as Potential Early Predictors of Response to Sorafenib in Hepatocellular Carcinoma by Satoshi Narahara, Takehisa Watanabe, Katsuya Nagaoka, Nahoko Fujimoto, Yoki Furuta, Kentaro Tanaka, Takayuki Tokunaga, Takeshi Kawasaki, Yoko Yoshimaru, Hiroko Setoyama, Kentaro Oniki, Junji Saruwatari, Masakuni Tateyama, Hideaki Naoe, Motohiko Tanaka, Yasuhito Tanaka, Yutaka Sasaki

“…Using high‐throughput screening and subsequent multivariate analysis in the derivation cohort, we found that changes in the concentrations of CLU, vascular cell adhesion molecule‐1 (VCAM1), and α‐fetoprotein were significantly associated with response to SFN. …”
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Exposure to radial extracorporeal shock waves modulates viability and gene expression of human skeletal muscle cells: a controlled in vitro study by Stefan G. Mattyasovszky, Eva K. Langendorf, Ulrike Ritz, Christoph Schmitz, Irene Schmidtmann, Tobias E. Nowak, Daniel Wagner, Alexander Hofmann, Pol M. Rommens, Philipp Drees

“…Cell viability and gene expression of the paired box protein 7 (Pax7), neural cell adhesion molecule (NCAM), and myogenic factor 5 (Myf5) and MyoD as muscle cell markers were compared to non-treated muscle cells that served as controls. …”
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Impact of Intratracheal Administration of Polyethylene Glycol-Coated Silver Nanoparticles on the Heart of Normotensive and Hypertensive Mice by Abderrahim Nemmar, Suhail Al-Salam, Yaser E. Greish, Sumaya Beegam, Nur E. Zaaba, Badreldin H. Ali

“…Similarly, the concentrations of endothelin-1, P-selectin, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 in heart homogenates were significantly higher than in the other two groups when HT mice were exposed to PEG–AgNPs. …”
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Impact of TNF and IL-33 Cytokines on Mast Cells in Neuroinflammation by Pio Conti, Gianpaolo Ronconi, Dorina Lauritano, Filiberto Mastrangelo, Alessandro Caraffa, Carla E. Gallenga, Ilias Frydas, Spyridon K. Kritas, Francesco Carinci, Federico Gaudelli, Ciro Annicchiarico, Cristian D’Ovidio

“…After its release into brain tissue, TNF rapidly induces the adhesion molecules endothelial leukocyte adhesion molecule 1 (ELAM-1), intercellular adhesion molecule 1 (ICAM-1), and vascular cell adhesion molecule 1 (VCAM-1) in endothelial cells. TNF causes the chemoattraction of neutrophils by inducing several molecules, including CXC chemokines (IL-8). …”
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CEACAM1 Is Associated With the Suppression of Natural Killer Cell Function in Patients With Chronic Hepatitis C by Takahiro Suda, Tomohide Tatsumi, Akira Nishio, Tadashi Kegasawa, Teppei Yoshioka, Ryoko Yamada, Kunimaro Furuta, Takahiro Kodama, Minoru Shigekawa, Hayato Hikita, Ryotaro Sakamori, Takasuke Fukuhara, Yoshiharu Matsuura, Tetsuo Takehara

“…In this study, we focused on carcinoembryonic antigen–related cell‐adhesion molecule 1 (CEACAM1). CEACAM1 is thought to suppress NK cell function. …”
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Arctium lappa L. roots inhibit the intestinal inflammation of dietary obese rats through TLR4/NF-κB pathway by Feng Zeng, Ying Li, Xiaoxiao Zhang, Jin Feng, Wen Gu, Li Shen, Wuyang Huang

“…These cytokines included interleukin (IL)-1β, IL-8, IL-6, tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1. The inhibition rates for all these cytokines exceeded 88 %. …”
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Feasibility of Imaging EpCAM Expression in Ovarian Cancer Using Radiolabeled DARPin Ec1 by Anzhelika Vorobyeva, Elena Konovalova, Tianqi Xu, Alexey Schulga, Mohamed Altai, Javad Garousi, Sara S. Rinne, Anna Orlova, Vladimir Tolmachev, Sergey Deyev

“…Epithelial cell adhesion molecule (EpCAM) is overexpressed in 55%–75% of ovarian carcinomas (OC). …”
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Gintonin Alleviates HCl/Ethanol- and Indomethacin-Induced Gastric Ulcers in Mice by Han-Sung Cho, Tae Woo Kwon, Ji-Hun Kim, Rami Lee, Chun-Sik Bae, Hyoung-Chun Kim, Jong-Hoon Kim, Sun-Hye Choi, Ik-Hyun Cho, Seung-Yeol Nah

“…The platelet endothelial cell adhesion molecule (PECAM-1), Evans blue, and occludin levels in gastric tissues were measured using immunofluorescence analysis. …”
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Clinicopathological and immunological profiles of prostate adenocarcinoma and neuroendocrine prostate cancer by Gang Huang, Huaru Zhang, Haoqing Shi, Wenhui Zhang, Tao Wang, Ziwei Wang, Qing Chen, Bijun Lian, Jing Li, Guosheng Yang

“…PCa samples from the 66 patients were analyzed using immunohistochemical staining for the detection of chromogranin, neural cell adhesion molecule 1, and synaptophysin. For tumor-associated immune microenvironment analysis, PD-L1, CD3, and CD8 were labeled in tissue slides. …”
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Circulating tumor cells as a prognostic biomarker in patients with hepatocellular carcinoma by Thaninee Prasoppokakorn, Areeya Buntho, Praewphan Ingrungruanglert, Thodsawit Tiyarattanachai, Tassanan Jaihan, Kittipat Kulkraisri, Darlene Ariyaskul, Chonlada Phathong, Nipan Israsena, Rungsun Rerknimitr, Sombat Treeprasertsuk, Roongruedee Chaiteerakij

“…CTCs were detected by immunoaffinity-based method using epithelial cell adhesion molecule (EpCAM) and mucin1 (MUC1). The CTCs detection rates of BCLC stages A, B, and C patients were 65.4% (17/26), 77.3% (17/22), and 96% (24/25), respectively, p = 0.018. …”
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Combined Targeting of AKT and mTOR Inhibits Tumor Formation of EpCAM⁺ and CD90⁺ Human Hepatocellular Carcinoma Cells in an Orthotopic Mouse Model by Mohamed Moustafa, Katarzyna-Krystyna Dähling, Armin Günther, Leonie Riebandt, Daniel J. Smit, Kristoffer Riecken, Carina Schröder, Ruimeng Zhuang, Till Krech, Malte Kriegs, Boris Fehse, Jakob R. Izbicki, Lutz Fischer, Björn Nashan, Jun Li, Manfred Jücker

“…The epithelial cell adhesion molecule (EpCAM) and Thy-1 cell surface antigen (CD90) have been implicated as cancer stem cell (CSC) markers in hepatocellular carcinoma (HCC). …”
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Human Amnion Epithelial Cells and Their Derived Exosomes Alleviate Sepsis-Associated Acute Kidney Injury via Mitigating Endothelial Dysfunction by Dongxuan Chi, Ying Chen, Ying Chen, Ying Chen, Ying Chen, Ying Chen, Chengang Xiang, Chengang Xiang, Chengang Xiang, Chengang Xiang, Chengang Xiang, Weijian Yao, Weijian Yao, Weijian Yao, Hui Wang, Xizi Zheng, Xizi Zheng, Xizi Zheng, Xizi Zheng, Xizi Zheng, Damin Xu, Damin Xu, Damin Xu, Damin Xu, Damin Xu, Nan Li, Min Xie, Suxia Wang, Gang Liu, Gang Liu, Gang Liu, Gang Liu, Gang Liu, Shuangling Li, Li Yang, Li Yang, Li Yang, Li Yang, Li Yang

“…Expression of phosphor-p65 (p-p65), p65, vascular cell adhesion molecule-1 (VCAM-1), and ZO-1 in the kidney were determined by Western blot.ResultshAECs decreased the mortality of CLP mice, ameliorated septic injury in the kidney, and improved kidney function. …”
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The Regulation of Endothelin-1 in Pregnancies Complicated by Gestational Diabetes: Uncovering the Vascular Effects of Insulin by Bianca R. Fato, Sally Beard, Natalie K. Binder, Natasha Pritchard, Tu’uhevaha J. Kaitu’u-Lino, Natasha de Alwis, Natalie J. Hannan

“…Human omental arteries from healthy pregnancies and those complicated by GDM were dissected from omental fat biopsies and collected at cesarean section. mRNA expression of ET-1 and its receptors, ET_A and ET_B, in addition to vascular cell adhesion molecule-1 (VCAM1) and intercellular adhesion molecule-1 (ICAM1) were assessed by qPCR (<i>n</i> = 28). …”
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