Influenza Virus Infections in Polarized Cells by Beatriz Praena, Xiu-Feng Wan

“…Furthermore, correct cell polarity and directional trafficking of molecules are essential for the orderly development of the system and affect successful influenza infection; on the other hand, influenza infection can also change cell polarity. …”
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Geometry Adaptation of Protrusion and Polarity Dynamics in Confined Cell Migration by David B. Brückner, Matthew Schmitt, Alexandra Fink, Georg Ladurner, Johannes Flommersfeld, Nicolas Arlt, Edouard Hannezo, Joachim O. Rädler, Chase P. Broedersz

“…However, it remains poorly understood how the dynamic interplay of these components and the cell polarity determine the emergent migration behavior at the cellular scale. …”
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Junctional Adhesion Molecules (JAMs): The JAM-Integrin Connection by Daniel Kummer, Klaus Ebnet

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ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development. by Sottocornola, R, Royer, C, Vives, V, Tordella, L, Zhong, S, Wang, Y, Ratnayaka, I, Shipman, M, Cheung, A, Gaston-Massuet, C, Ferretti, P, Molnár, Z, Lu, X

“…Cell polarity plays a key role in the development of the central nervous system (CNS). …”

Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton. by Dawe, H, Adams, M, Wheway, G, Szymanska, K, Logan, C, Noegel, A, Gull, K, Johnson, C

“…However, in ciliated-cell models, meckelin and nesprin-2 isoforms colocalized at filopodia prior to the establishment of cell polarity and ciliogenesis. Loss of nesprin-2 and nesprin-1 shows that both mediate centrosome migration and are then essential for ciliogenesis, but do not otherwise affect apical-basal polarity. …”

The polarity protein Baz forms a platform for the centrosome orientation during asymmetric stem cell division in the Drosophila male germline by Mayu Inaba, Zsolt G Venkei, Yukiko M Yamashita

“…Our work provides a foundation for understanding how the correct cell polarity may be recognized by the cell to ensure productive ACD.…”
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Formation of polarity convergences underlying shoot outgrowths by Katie Abley, Susanna Sauret-Güeto, Athanasius FM Marée, Enrico Coen

“…The development of outgrowths from plant shoots depends on formation of epidermal sites of cell polarity convergence with high intracellular auxin at their centre. …”
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The Rb tumor suppressor regulates epithelial cell migration and polarity by Parisi, Tiziana, Balsamo, Michele, Gertler, Frank, Lees, Jacqueline

“…Altered cell polarity and migration are hallmarks of cancer and metastases. …”
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Investigation of Par3 and RASSF7 interaction by Seah, Pei Ying

“…Cell polarity is regulated by a complex network of interactions between different polarity proteins. …”
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Impact of HCV Infection on Hepatocyte Polarity and Plasticity by Jean Agnetti, Christophe Desterke, Ama Gassama-Diagne

“…The hepatitis C virus (HCV) is an oncogenic virus that alters the cell polarization machinery in order to enter the hepatocyte and replicate. …”
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Rho and Rab Family Small GTPases in the Regulation of Membrane Polarity in Epithelial Cells by Klaus Ebnet, Klaus Ebnet, Klaus Ebnet, Volker Gerke, Volker Gerke, Volker Gerke

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Protein Phosphatase 2A: More Than a Passenger in the Regulation of Epithelial Cell–Cell Junctions by Diana Schuhmacher, Jean-Marie Sontag, Jean-Marie Sontag, Estelle Sontag, Estelle Sontag

“…Cell–cell adhesion plays a key role in the maintenance of the epithelial barrier and apicobasal cell polarity, which is crucial for homeostasis. Disruption of cell–cell adhesion is a hallmark of numerous pathological conditions, including invasive carcinomas. …”
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Synaptic asymmetry to go. by Dustin, M

“…Cell polarity is critical for T lymphocyte movement during their hunt for antigen-bearing cells and for infected target cells. …”

Efficiency of transcription and translation of cell-free protein synthesis systems in cell-sized lipid vesicles with changing lipid composition determined by fluorescence measureme... by Akari Miwa, Masatoshi Wakamori, Tetsuro Ariyoshi, Yasushi Okada, Mikako Shirouzu, Takashi Umehara, Koki Kamiya

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<i>LLGL2</i> Inhibits Ovarian Cancer Metastasis by Regulating Cytoskeleton Remodeling via <i>ACTN1</i> by Qiu-Ying Gu, Yue-Xi Liu, Jin-Long Wang, Xiao-Lan Huang, Ruo-Nan Li, Hua Linghu

“…<i>LLGL2</i>, as a cell polarity factor, is involved in maintaining cell polarity and asymmetric cell division. …”
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Afadin couples RAS GTPases to the polarity rheostat Scribble by Marilyn Goudreault, Valérie Gagné, Chang Hwa Jo, Swati Singh, Ryan C. Killoran, Anne-Claude Gingras, Matthew J. Smith

“…Goudreault et al. investigate the role of Afadin downstream of RAS GTPases, substantiating this cell adhesion protein as a true RAS effector that couples its activation to cell polarity through the Scribble protein.…”
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Golgi Complex: A Signaling Hub in Cancer by Daniela Spano, Antonino Colanzi

“…In addition, it is an active signaling hub involved in the regulation of multiple cellular processes, including cell polarity, motility, growth, autophagy, apoptosis, inflammation, DNA repair and stress responses. …”
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p21-activated kinase 1: PAK'ed with potential. by Ong, C, Jubb, A, Zhou, W, Haverty, P, Harris, A, Belvin, M, Friedman, L, Koeppen, H, Hoeflich, K

“…The p21-activated kinases (PAKs) are central players in growth factor signaling networks and morphogenetic processes that control proliferation, cell polarity, invasion and actin cytoskeleton organization. …”

Extracellular Matrix components regulate cellular polarity and tissue structure in the developing and mature Retina by Shweta Varshney, Dale D Hunter, William J Brunken

“…In addition to their effects on the developing retina, laminins play a role in maintaining Müller cell polarity and compartmentalization, thereby contributing to retinal homeostasis. …”
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Cell-cell interactions that drive tumorigenesis in Drosophila by Masato Enomoto, Tatsushi Igaki

“…This led to the identification of oncogenic cell-cell interactions triggered by endocytic dysregulation, mitochondrial dysfunction, cell polarity defects, or Src activation in Drosophila imaginal epithelia. …”
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