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81
Plastoglobules: a new address for targeting recombinant proteins in the chloroplast
Published 2007-01-01“…Chloroplasts have proven a useful cellular compartment for protein accumulation owing to their large size and number, as well as the possibility for organellar transformation. …”
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82
Identification of a foetal epigenetic compartment in adult human kidney
Published 2022-03-01“…FCO associated genes also mapped to medullary nephron segments in mouse and rat, suggesting evolutionary conservation of this cellular compartment. Renal cancer patients whose tumours contained non-zero FCO scores survived longer. …”
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83
CELLO2GO: a web server for protein subCELlular LOcalization prediction with functional gene ontology annotation.
Published 2014-01-01“…When homologs for the query sequence have been identified, the number of terms found for each of their GO categories, i.e., cellular compartment, molecular function, and biological process, are summed and presented as pie charts representing possible functional annotations for the queried protein. …”
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84
An FPT approach for predicting protein localization from yeast genomic data.
Published 2011-01-01“…Accurately predicting the localization of proteins is of paramount importance in the quest to determine their respective functions within the cellular compartment. Because of the continuous and rapid progress in the fields of genomics and proteomics, more data are available now than ever before. …”
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85
Prospects of Using Protein Engineering for Selective Drug Delivery into a Specific Compartment of Target Cells
Published 2023-03-01“…However, proteins, like other macromolecules, cannot, as a rule, freely penetrate into the desired cellular compartment. Recent studies allow us to design multifunctional proteins that solve these problems. …”
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86
Computational Analysis of Chromophore Tripeptides FollowingFusion of Enhanced Green Fluorescent Protein and Cell-FollowingFusion of Enhanced Green Fluorescent Protein and Cell-pene...
Published 2020-12-01“…Cell-penetrating peptides (CPPs) are small peptides that can transfer other materials into a cellular compartment. In this research, we studied the effect of fusion of new CPPs to the N-terminal of enhanced Green Fluorescent Protein eGFP on the ability of the latter to fluoresce. …”
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87
Why Corals Care About Ocean Acidification: Uncovering the Mechanism
Published 2009-12-01“…The concentration of carbonate ions relative to other carbonate species in seawater is rather low, so corals expend energy to raise the pH of seawater sequestered in an isolated, extra-cellular compartment where crystal growth occurs. This action converts plentiful bicarbonate ions to the carbonate ions required for calcification, allowing corals to produce CaCO3 about 100 times faster than it could otherwise form. …”
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88
Genetically Encoded ATP Biosensors for Direct Monitoring of Cellular ATP Dynamics
Published 2022-06-01“…It is suggested that ATP from different cellular compartments can dynamically communicate and coordinate to adapt to the needs in each cellular compartment. …”
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89
An Overview of Current Pretreatment Methods Used to Improve Lipid Extraction from Oleaginous Micro-Organisms
Published 2018-06-01“…Lipids are synthesized in the cellular compartment of oleaginous microorganisms in the form of lipid droplets, so it is necessary to disrupt the cells prior to lipid extraction in order to improve the extraction yields. …”
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90
The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells.
Published 2008-02-01“…The endoplasmic reticulum (ER) is a cellular compartment for the biosynthesis and folding of newly synthesized secretory proteins such as insulin. …”
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91
ALA6, a P4-type ATPase, Is Involved in Heat Stress Responses in Arabidopsis thaliana
Published 2017-10-01“…The differentially expressed genes are involved primarily in the physiological processes of stress response, cellular compartment maintenance, macromolecule stability and energy production. …”
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92
Genome-wide study of mRNA degradation and transcript elongation in Escherichia coli
Published 2018“…An essential part of gene expression is the coordination of RNA synthesis and degradation, which occurs in the same cellular compartment in bacteria. Here, we report a genome‐wide RNA degradation study in Escherichia coli using RNA‐seq, and present evidence that the stereotypical exponential RNA decay curve obtained using initiation inhibitor, rifampicin, consists of two phases: residual RNA synthesis, a delay in the interruption of steady state that is dependent on distance relative to the mRNA's 5′ end, and the exponential decay. …”
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93
Behavioral and Cellular Tagging in Young and in Early Cognitive Aging
Published 2022-02-01“…Here, we investigated in male rats how sub-regions of the hippocampus are involved in memory representation in behavioral tagging and how early aging affects such representation by combining behavioral training in appetitive delayed-matching-to-place tasks with the “cellular compartment analysis of temporal activity by fluorescence in situ hybridization” technique. …”
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94
Conformational Dynamics Related to Membrane Fusion Observed in Single Ebola GP Molecules
Published 2020-06-01“…Thus, the GP senses the cellular environment to protect against triggering prior to the arrival of EBOV in a permissive cellular compartment.…”
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95
Aging is associated with increased brain iron through cortex-derived hepcidin expression
Published 2022-01-01“…However, the mechanism for this increase in iron with aging, and whether this increase is localized to specific cellular compartment(s), are not known. Here, we measured the levels of iron in different tissues of aged mice, and demonstrated that while cytosolic non-heme iron is increased in the liver and muscle tissue, only the aged brain cortex exhibits an increase in both the cytosolic and mitochondrial non-heme iron. …”
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96
Dual targeting of peroxisomal proteins
Published 2013-10-01“…While some metabolic reactions are specific to a single organelle, others occur in more than one cellular compartment. Specific targeting of proteins to compartments inside of eukaryotic cells is mediated by defined sequence motifs. …”
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97
Heterogeneity in neutrophil responses to immune complexes
Published 2019-10-01“…Examination of individuals at the extremes of reactivity (high vs low) shows that phenotypic variation resides in the cellular compartment and is correlated with host white blood cell count and absolute neutrophil count, but not age, sex, race, polymorphisms in neutrophil Fcγ receptors, or CR1, CR3, and Fcγ receptor expression on neutrophils. …”
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98
Broadening the functionality of a J-protein/Hsp70 molecular chaperone system.
Published 2017-10-01“…Targeting to specific locations within a cellular compartment and binding of specific substrates for delivery to Hsp70 have been identified as modes of J-protein specialization. …”
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99
Role of CXCR5+ CD8+ T cells in human immunodeficiency virus-1 infection
Published 2022-11-01“…Memory CD4+ T cell subsets, especially T follicular helper (TFH) cells that reside in B-cell follicles within lymphoid tissues, are regarded as the predominant cellular compartment of the HIV reservoir. Substantial evidence indicates that HIV-specific CD8+ T cell-mediated cellular immunity can sustain long-term disease-free and transmission-free HIV control in elite controllers. …”
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100
Fluid mechanics of luminal transport in actively contracting endoplasmic reticulum
Published 2024-12-01“…The endoplasmic reticulum (ER), the largest cellular compartment, harbours the machinery for the biogenesis of secretory proteins and lipids, calcium storage/mobilisation, and detoxification. …”
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