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Conformational Dynamics Related to Membrane Fusion Observed in Single Ebola GP Molecules
Published 2020-06-01“…Thus, the GP senses the cellular environment to protect against triggering prior to the arrival of EBOV in a permissive cellular compartment.…”
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102
Eukaryotic protein production in designed storage organelles
Published 2009-01-01“…Recombinant protein encapsulation in these PBs facilitates stable accumulation of proteins in a protected sub-cellular compartment which results in an enhancement of protein production without affecting the viability and development of stably transformed hosts. …”
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103
Interaction of client—the scaffold on which FeS clusters are build—with J-domain protein Hsc20 and its evolving Hsp70 partners
Published 2022-10-01“…Analysis of this switching of Hsp70 partners has provided insight into the insulation of JDP/Hsp70 systems from one another that can occur when more than one Hsp70 is present in a cellular compartment, as well as how competition among JDPs is balanced when an Hsp70 partner is shared amongst a number of JDPs. …”
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104
Phenotypic variability in synthetic biology applications: dealing with noise in microbial gene expression.
Published 2016-04-01“…The stochasticity due to the infrequent collisions among low copy-number molecules within the crowded cellular compartment is a feature of living systems. Single cell variability in gene expression within an isogenic population (i.e. biological noise) is usually described as the sum of two independent components: intrinsic and extrinsic stochasticity. …”
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105
Toll-like receptors and their soluble forms differ in the knee and thumb basal osteoarthritic joints
Published 2017-05-01“…Results — In contrast to knee OA, TLR expression in CMC-I OA did not show grade-dependent overall profile changes, but PCA revealed that TLR expression profiles clustered according to their cellular compartment organization. Protein levels of TLR4 were substantially higher in knee OA than in CMC-I OA, while the opposite was the case at the mRNA level. …”
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106
Pharmacokinetics, biological effects, and distribution of (1→3)-β-D-glucan in blood and organs in rabbits
Published 1997-01-01“…Less than 3% of the 125I-(1→3)-β-D-glucan was initially associated with the cellular compartment, and this value decreased further during the 2-h period following administration (P = 0.0001). …”
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107
Lysosomal hydrolases, from waste-bags effectors to essential multipurpose enzymes in liver fibrosis
Published 2023-02-01“…There are more than 50 different lysosomal hydrolases that display optimal activity in the pH present in the acidic cellular compartment but can also be found in other cellular locations. …”
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108
Donor hematopoietic stem cells confer long-term marrow reconstitution by self-renewal divisions exceeding to that of host cells.
Published 2012-01-01“…The proliferation of LSK cells was associated with the onset of colossal expression of different hematopoietic growth factor genes in non-hematopoietic cellular compartment. Activation of donor LSK cells was found to be dynamically controlled by BM cellularity. …”
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109
Toll-interacting protein modulates colitis susceptibility in mice
Published 2014“…Bone marrow chimeras were generated to identify the cellular compartment, whereby Tollip may negatively regulate intestinal inflammation in response to DSS. …”
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110
Proteomic analysis of the cell-surface membrane in chronic lymphocytic leukemia: identification of two novel proteins, BCNP1 and MIG2B.
Published 2003“…Using this method, many known B-cell surface antigens were detected, but also known proteins not previously described in this disease or in this cellular compartment, including cell surface receptors, membrane-associated enzymes and secreted proteins, and completely unknown proteins. …”
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111
Effect of osmotic dehydration on kiwifruit: Results of a multianalytical approach to structural study
Published 2011-01-01“…This paper presents the results of the comparison of different analytical techniques (Differential Scanning Calorimetry - DSC, Low Field Nuclear Magnetic Resonance - LF-NMR, Light Microscopy - LM and Transmission Electron Microscopy - TEM) in order to evaluate the mass transfer, water status and cellular compartment modifications of the kiwifruit outer pericarp tissue during osmotic dehydration treatment (OD). …”
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112
Urokinase plasminogen activator inhibits HIV virion release from macrophage-differentiated chronically infected cells via activation of RhoA and PKCε.
Published 2011-01-01“…Interaction of urokinase-type plasminogen activator (uPA) with its cell surface receptor (uPAR) has been shown to favor virion accumulation in such sub-cellular compartment in primary monocyte-derived macrophages and chronically infected promonocytic U1 cells differentiated into macrophage-like cells by stimulation with phorbol myristate acetate (PMA). …”
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113
Characterization of a Novel Endoplasmic Reticulum Protein Involved in Tubercidin Resistance in Leishmania major.
Published 2016-09-01“…TRP immunolocalization revealed that it was co-localized to the endoplasmic reticulum (ER), a cellular compartment with many functions. In silico predictions indicated that TRP contains only a hypothetical transmembrane domain. …”
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114
Understanding the role of potential biomarkers in attenuating multiple sclerosis progression via multiomics and network-based approach.
Published 2024-01-01“…WGCN revealed a total of 122 hub DEGs of which most significant pathway, gene ontology (GO)-biological process (BP), GO-molecular function (MF) and GO-cellular compartment (CC) terms were assembly and cell surface presentation of N-methyl-D-aspartate (NMDA) receptors, regulation of catabolic process, NAD(P)H oxidase H2O2 forming activity, postsynaptic recycling endosome. …”
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115
Role of NR4A family members in myeloid cells and leukemia
Published 2022-01-01“…The myeloid cellular compartment comprises monocytes, dendritic cells (DCs), macrophages and granulocytes. …”
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A histochemical reporter system to study extracellular ATP response in plants
Published 2023-06-01“…When cells experience acute mechanical distress, they release ATP from their cellular compartment into the surrounding microenvironment. …”
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118
Generation of bovine decellularized testicular bio-scaffolds as a 3D platform for testis bioengineering
Published 2025-01-01“…In particular, bovine testes are subjected to three different decellularization protocols. Cellular compartment removal and extracellular matrix preservation are evaluated. …”
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119
Proteomic interrogation of the meninges reveals the molecular identities of structural components and regional distinctions along the CNS axis
Published 2023-10-01“…This pattern was also seen when total proteins were subdivided by cellular compartment, except in the case of the ECM category where brain and spinal meninges each had near equal number of unique proteins, and Type V and type III collagen registered exclusively in the spine. …”
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Simultaneous production of DHA and squalene from Aurantiochytrium sp. grown on forest biomass hydrolysates
Published 2019-10-01“…Thraustochytrids are heterotrophic marine oleaginous microorganisms capable of synthesizing high amounts of DHA, as well as other nutraceutical compounds such as squalene, in their cellular compartment. Squalene is a natural triterpene and an important biosynthetic precursor to all human steroids. …”
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