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Hydrogen peroxide probes directed to different cellular compartments.
Published 2011-01-01“…When targeted to various cellular compartments, HyPer occurred in the reduced state in the nucleus, cytosol, peroxisomes, mitochondrial intermembrane space and mitochondrial matrix, but low levels of the oxidized form of the biosensor were also observed in each of these compartments, consistent with a low peroxide tone in mammalian cells. …”
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When Place Matters: Shuttling of Enolase-1 Across Cellular Compartments
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Metabolic and Cellular Compartments of Acetyl-CoA in the Healthy and Diseased Brain
Published 2022-09-01“…It is also used for hundreds of acetylation reactions, including N-acetyl aspartate synthesis in neuronal mitochondria, acetylcholine synthesis in cholinergic neurons, as well as divergent acetylations of several proteins, peptides, histones and low-molecular-weight species in all cellular compartments. Therefore, acetyl-CoA should be considered as the central point of metabolism maintaining equilibrium between anabolic and catabolic pathways in the brain. …”
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Overcoming Chemoresistance: Altering pH of Cellular Compartments by Chloroquine and Hydroxychloroquine
Published 2021-02-01“…The present review summarizes effects of CQ, HCQ and proton pump inhibitors on pH of various cellular compartments and discuss potential mechanisms underlying their pH-dependent anti-cancer effects. …”
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HyPer as a tool to determine the reductive activity in cellular compartments
Published 2024-04-01“…Here, we advocate for repurposing HyPer1, initially designed as a fluorescent probe for H2O2 levels, as a tool to measure the reductive power in various cellular compartments. The response of HyPer1 depends on kinetics between thiol oxidation and reduction in its OxyR sensing domain. …”
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Bridging the gap: linking molecular simulations and systemic descriptions of cellular compartments.
Published 2010-01-01“…Such an analysis identifies the crucial system parameters and guides the setup of new experiments that would add most knowledge for a systemic understanding of cellular compartments. The successful combination of the molecular model and the systemic parametrization presented here on the example of the simple machinery for bacterial photosynthesis shows that it is actually possible to combine molecular and systemic modeling. …”
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Cellular compartments cause multistability and allow cells to process more information.
Published 2013Journal article -
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Internuclear diffusion of histone H1 within cellular compartments of Aspergillus nidulans.
Published 2018-01-01“…In time-lapse analyses, we observed stochastic exchange of photoactivated Dendra2-histone H1 protein between nuclei within the same cellular compartment. We also observed exchange of histones between genetically distinct nuclei in a heterokaryon derived from fusion of strains carrying histone H1-RFP or H1-GFP. …”
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Non-coding RNA Regulated Cross-Talk Between Mitochondria and Other Cellular Compartments
Published 2021-08-01“…In addition, mitochondria have to quickly respond to changes inside and outside the cells and have their own functional states reported to the nucleus and other cellular compartments. The underlying molecular mechanisms of these complex regulations have not been well understood. …”
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Prospects of electron cryotomography to visualize macromolecular complexes inside cellular compartments: implications of crowding.
Published 2003“…Second, electron cryotomography offers an incisive probe to examine crowding in different cellular compartments.…”
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MyD88 signalling from distinct cellular compartments drives intestinal inflammation
Published 2008Conference item -
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Calciprotein Particles Induce Cellular Compartment-Specific Proteome Alterations in Human Arterial Endothelial Cells
Published 2023-12-01“…Here, we performed a pathway enrichment analysis of cellular compartment-specific proteomes in primary human coronary artery ECs (HCAEC) and human internal thoracic artery ECs (HITAEC) treated with primary (amorphous) or secondary (crystalline) CPPs (CPP-P and CPPs, respectively). …”
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Fluctuations in cell density alter protein markers of multiple cellular compartments, confounding experimental outcomes.
Published 2019-01-01“…On the other hand, allometric scaling of cellular compartments in growing cell populations resulted in biochemically detectable changes in the plasma membrane proteins Na+K+-ATPase and cadherin, and nuclear proteins HDAC1 and Lamin B1. …”
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Distinct redox regulation in sub-cellular compartments in response to various stress conditions in Saccharomyces cerevisiae.
Published 2013-01-01“…This study presents the first direct measurement of pH-adjusted redox state in sub-cellular compartments during growth and stress conditions. …”
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Coral lipid bodies as the relay center interconnecting diel-dependent lipidomic changes in different cellular compartments
Published 2017-06-01“…Using the scleractinian Euphyllia glabrescens collected across the diel cycle, we observed temporally dynamic lipid profiles in three cellular compartments: host coral gastrodermal cells, LBs, and in hospite Symbiodinium. …”
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