Accurate diagnosis of bronchopulmonary Talaromyces marneffei infection in an anti-IFN-γ autoantibodies positive patient assisted by endobronchial ultrasound-guided TBNA and mNGS: a... by Guirong Chen, Nan Ma, Donglan Zhu, Huaihai Zhou, Qiumei Liang, Jianfeng Meng, Yin Shen, Hang Liu, Liu Liu, Zhiyi He, Zhiqiang Qin

“…Patient concerns: A 56-year-old Chinese man presented with a 5-month history of intermittent low or high fever and dry cough, followed by fatigue, night sweating, and chest pain when coughing. A large hilar lesion in the left lung and multiple mediastinal lymph node enlargements were found on his chest CT scan. …”
Get full text

Hybrid‐Mobile Stroke Unit: Opening the Indication Spectrum for Stroke Mimics and Beyond by Klaus Fassbender, Daniel J. Phillips, Iris Q. Grunwald, Andrea Schottek, Sajid Alam, Saman Perera, Annie Chakrabarti, Robert Moon, Martin Lesmeister, Viola Wagner, Damon Wheddon, David Dommett, Brittany Wells, Rheanne Middleton, Robert Willis, Monika Bachhuber, Fatma Merzou, Stefan Wagenpfeil, Jineesh Thottath, Thomas Bertsch, Silke Walter

“…Apart from patients with a dispatch code for “stroke”, the ambulance was also dispatched to those with codes for “seizures”, “falls with head trauma”, “headache”, “unconsciousness”, “infection and pandemic”, “chest pain”, and “breathing problems”. Results For 250 patients treated by the Hybrid‐MSU, but not for 250 conventionally treated patients, the prehospital diagnostic workup allowed, apart from treatment with stroke thrombolytics (n=15), prehospital administration of specific anticonvulsants (n=15), antibiotics (n=5), early secondary stroke prophylaxis with aspirin (n=49), and the Sepsis Six bundle (n=2). …”
Get full text

Exposure to echimidine impairs the heart development and function of zebrafish larvae by Tingting Lin, Li Zhou, Zhibin Chen, Luanjin Wang, Jian Yang, Sheng Wang, Xintan Chen, Zhenghong Zuo, Chengyong He, Lanping Guo

Get full text

A Prospective Multicenter Longitudinal Analysis of Suicidal Ideation among Long-COVID-19 Patients by Alessandra Costanza, Andrea Amerio, Andrea Aguglia, Luca Magnani, Jacques Alexander, Alessandra Maiorano, Hélène Richard-Lepouriel, Elena Portacolone, Isabella Berardelli, Maurizio Pompili, Gianluca Serafini, Mario Amore, Khoa D. Nguyen

“…Baseline and SI-onset levels of inflammatory mediators in plasma samples, along with 12 long-COVID-19 features (post-exertional malaise, fatigue, brain fog, dizziness, gastrointestinal disturbance, palpitations, changes in sexual desire/capacity, loss/change of smell/taste, thirst, chronic cough, chest pain, and abnormal movements) will be collected for SI risk analysis. …”
Get full text

Prevalence and determinants of healthcare avoidance during the COVID-19 pandemic: A population-based cross-sectional study. by Marije J Splinter, Premysl Velek, M Kamran Ikram, Brenda C T Kieboom, Robin P Peeters, Patrick J E Bindels, M Arfan Ikram, Frank J Wolters, Maarten J G Leening, Evelien I T de Schepper, Silvan Licher

“…Of those, 414 participants (36.3%) reported symptoms that potentially warranted urgent evaluation, including limb weakness (13.6%), palpitations (10.8%), and chest pain (10.2%). Determinants related to avoidance were older age (adjusted OR 1.14 [95% confidence interval (CI) 1.08 to 1.21]), female sex (1.58 [1.38 to 1.82]), low educational level (primary education versus higher vocational/university 1.21 [1.01 to 1.46), poor self-appreciated health (per level decrease 2.00 [1.80 to 2.22]), unemployment (versus employed 2.29 [1.54 to 3.39]), smoking (1.34 [1.08 to 1.65]), concern about contracting COVID-19 (per level increase 1.28 [1.19 to 1.38]) and symptoms of depression (per point increase 1.13 [1.11 to 1.14]) and anxiety (per point increase 1.16 [1.14 to 1.18]). …”
Get full text

An Artificial Intelligence-Based Alarm Strategy Facilitates Management of Acute Myocardial Infarction by Wen-Cheng Liu, Chin Lin, Chin-Sheng Lin, Min-Chien Tsai, Sy-Jou Chen, Shih-Hung Tsai, Wei-Shiang Lin, Chia-Cheng Lee, Tien-Ping Tsao, Cheng-Chung Cheng

“…The components of AI-S consisted of chest pain symptoms, a 12-lead ECG, and high-sensitivity troponin I. …”
Get full text

Vitamin D: A Role Also in Long COVID-19? by Luigi Barrea, Ludovica Verde, William B. Grant, Evelyn Frias-Toral, Gerardo Sarno, Claudia Vetrani, Florencia Ceriani, Eloisa Garcia-Velasquez, José Contreras-Briceño, Silvia Savastano, Annamaria Colao, Giovanna Muscogiuri

“…Common symptoms include fatigue, shortness of breath, cough, joint pain, chest pain, muscle aches, headaches, and so on. Vitamin D is an immunomodulatory hormone with proven efficacy against various upper respiratory tract infections. …”
Get full text

Sex and gender differences in myocarditis and dilated cardiomyopathy: An update by DeLisa Fairweather, DeLisa Fairweather, DeLisa Fairweather, Danielle J. Beetler, Danielle J. Beetler, Danielle J. Beetler, Nicolas Musigk, Bettina Heidecker, Melissa A. Lyle, Leslie T. Cooper, Katelyn A. Bruno, Katelyn A. Bruno

“…In a small study, more men with myocarditis presented with symptoms of chest pain while women presented with dyspnea. Men with myocarditis have been found to have higher levels of heart failure biomarkers soluble ST2, creatine kinase, myoglobin and T helper 17-associated cytokines while women develop a better regulatory immune response. …”
Get full text

Use of a Smartphone Self-assessment App for a Tobacco-Induced Disease (COPD, Cardiovascular Diseases, Cancer) Screening Strategy and to Encourage Smoking Cessation: Observational S... by Edouard Stavaux, François Goupil, Guillaume Barreau, Anne Lise Septans, Bertrand Dautzenberg, Armelle Foulet-Rogé, Norbert Padilla, Thierry Urban, Fabrice Denis

“…The most frequent symptoms triggering the notifications were fatigue (2023/5671, 35.7%), cough (1658/5671, 29.2%), dyspnea (1502/5671, 26.5%), and persistent chest pain (1286/5671, 22.7%). Of the current smokers, 14.0% (515/3679) showed symptoms suggesting COPD, 15.5% (571/3679) showed symptoms suggesting stable angina, 12.4% (455/3679) probably had lower extremity artery disease, and 6.8% (249/3679) had possible cancer. …”
Get full text

Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disea... by Peter Loof Møller, Palle Duun Rohde, Jonathan Nørtoft Dahl, Laust Dupont Rasmussen, Louise Nissen, Samuel Emil Schmidt, Victoria McGilligan, Daniel F. Gudbjartsson, Kari Stefansson, Hilma Holm, Jacob Fog Bentzon, Morten Bøttcher, Simon Winther, Mette Nyegaard

“…Methods Consecutive chest pain patients (n = 1462) undergoing CCTA to diagnose obstructive coronary artery disease (CAD) were included. …”
Get full text

Clinical Predictors of Mortality in Prehospital Distress Calls by Emergency Medical Service Subscribers by Gabby Elbaz-Greener, Shemy Carasso, Elad Maor, Lior Gallimidi, Merav Yarkoni, Harindra C. Wijeysundera, Yitzhak Abend, Yinon Dagan, Amir Lerman, Offer Amir

“…Age above 80 years (OR 3.34; 95% CI 3.03–3.69, <i>p</i> < 0.005), first EMS SBP ≤ 130 mm Hg (OR 2.61; 95% CI 2.36–2.88, <i>p</i> < 0.005), dyspnea at presentation (OR 2.55; 95% CI 2.29–2.83, <i>p</i> < 0001), and chest pain with ischemic ECG changes (OR 1.95; 95% CI 1.71–2.23, <i>p</i> < 0.001) were the highest predictors of 1 month mortality and remained so for mortality at 3 and 12 months. …”
Get full text

Russian register of acute pulmonary embolism SIRENA: characteristics of patients and in-hospital treatment by A. D. Erlikh, A. N. Atakanova, A. G. Neeshpapa, N. A. Cherepanova, I. S. Mullova, O. L. Barbarash, S. A. Berns, E. A. Shmidt, D. V. Duplyakov

“…Shortness of breath, syncope/presyncope, chest pain/discomfort, cough, leg pain or lower extremity asymmetry and hemoptysis were noted in 88,7%, 30,0%, 29,8%, 17,3%, 9,4% and 8,5% of patients, respectively. …”
Get full text

Autoimmune polyendocrine syndrome II presenting paradoxically as Takotsubo cardiomyopathy: a case report and reappraisal of pathophysiology by Akash Batta, Amit Kumar Gupta, Gautam Singal, Bishav Mohan, Sushil Kumar, Bhavuk Jaiswal, Juniali Hatwal, Rohit Tandon, Gurbhej Singh, Abhishek Goyal, Bhupinder Singh, Naveen Mittal, Shibba Takkar Chhabra, Naved Aslam, Gurpreet Singh Wander

“…Case presentation A 50-year-old woman with past history of hypothyroidism presented to emergency department with history of acute chest pain and syncope. There was no significant drug history or history of an emotional or physical stimulus prior to admission. …”
Get full text

Clinical effectiveness of rehabilitation in ambulatory care for patients with persisting symptoms after COVID-19: a systematic review by Hannelore Dillen, Geertruida Bekkering, Sofie Gijsbers, Yannick Vande Weygaerde, Maarten Van Herck, Sarah Haesevoets, David A G Bos, Ann Li, Wim Janssens, Rik Gosselink, Thierry Troosters, Jan Y Verbakel

“…Physical training and breathing exercises may reduce fatigue, dyspnoea, and chest pain and may improve physical capacity and quality of life, but the evidence is very weak (based on 6 RCTs and 12 cohort studies). …”
Get full text

Assessment of mitral annular velocities by Doppler tissue imaging in predicting left ventricular thrombus formation after first anterior acute myocardial infarction by Ahmed Fathy, Ghada Ibrahim, Ahmed Shaker

“…Patients and methods: Patients included in our study represented by first time anterior wall acute myocardial infarction who met the following criteria; chest pain lasting more than 30 min, ST segment elevation greater than 2 mm in two consecutive anterior electrographic leads and transient elevation of biochemical cardiac markers. …”
Get full text

Clinical profile and 30-day outcome of patients with acute coronary syndrome by Sumi Dutta, Naruttam Sonowal, Kaberi Mech, Alokjyoti Malakar, Himavathy Kodandarao Gara, Dharma Rao Vanamali

“…Hypertension, obesity, smoking, and family history of ACS were reported by 40%, 30%, 30%, and 27.27% of patients, respectively. Chest pain was the commonest symptom, followed by sweating and radiating pain. …”
Get full text

Abstract 152: Exploring Age‐related Changes in Brain Metabolism among Individuals with Cardiovascular Risk Factors: An FDG‐PET Analysis by Eric M. Teichner, Robert C. Subtirelu, Tom Werner, Abass Alavi

“…Participants were recruited from a group of patients with chest pain syndromes who were referred for coronary CT angiography. …”
Get full text

Synthetic Cannabinoids (SCs) K2 clinical manifestation-A literature review by S. Kamrun, T. Sultana, F. A. Faruki, S. Goddu

“…Cross-sectional study on 50 male cases showed altered perception 68%, including auditory and visual hallucination, dizziness and loss of consciousness, palpitation 76%, chest pain 12%, panic attack, and convulsion [Abdelmoneim WM et al. …”
Get full text

Clinical Method Applied to Focused Ultrasound: The Case of Wells’ Score and Echocardiography in the Emergency Department: A Systematic Review and a Meta-Analysis by Lorenzo Falsetti, Vincenzo Zaccone, Alberto M. Marra, Nicola Tarquinio, Giovanna Viticchi, Mattia Sampaolesi, Francesca Riccomi, Laura Giovenali, Consuelo Ferrini, Gianluca Moroncini, Cinzia Nitti, Aldo Salvi

“…However, a focused cardiac and thoracic ultrasound investigation is useful for the differential diagnosis of dyspnea and chest pain in the ED.…”
Get full text

Exploring long COVID condition in Latin America: Its impact on patients’ activities and associated healthcare use by Adriana Angarita-Fonseca, Adriana Angarita-Fonseca, Adriana Angarita-Fonseca, Rodrigo Torres-Castro, Vicente Benavides-Cordoba, Santos Chero, Mauricio Morales-Satán, Bricia Hernández-López, Rafael Salazar-Pérez, Santiago Larrateguy, Santiago Larrateguy, Diana C. Sanchez-Ramirez

“…LCC respondents who reduced their activities reported more difficulty sleeping, chest pain with activity, depression, and problems with concentration, thinking, and memory, while those who needed help with ADLs were more likely to have difficulty walking, and shortness of breath at rest. …”
Get full text